Symbols / APRE Stock $0.90 -3.26% Aprea Therapeutics, Inc.

Healthcare • Biotechnology • United States • NCM
APRE (Stock) Chart
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Stock Fundamentals
Scroll to Statements
Index EQUITY
Sector Healthcare
Industry Biotechnology
CEO Dr. Oren Gilad Ph.D.
Exch · Country NCM · United States
Market Cap 11.14M
Enterprise Value -3.56M
Income -12.60M
Sales 285.76K
FCF (ttm) -8.56M
Book/sh 1.52
Cash/sh 1.27
Employees 8
Insider 10d
IPO Oct 03, 2019
Div forward ($/yr)
Div TTM ($/yr)
Dividend Yield
Ex-Div Date
5Y Avg Yield
Yield vs 5Y Avg
Payout 0.00%
P/E
Forward P/E -1.36
PEG
P/S 39.00
P/B 0.59
P/C
EV/EBITDA 0.27
EV/Sales -12.47
Quick Ratio 5.28
Current Ratio 5.63
Debt/Eq
LT Debt/Eq
EPS (ttm) -1.93
EPS next Y -0.66
EPS Growth
Revenue Growth -98.40%
EPS Gr Q/Q
Rev Gr Q/Q
Earnings (next) 2026-03-16
Earnings (prior) 2026-03-16
ROA -41.45%
ROE -74.58%
ROIC
Gross Margin 0.00%
Oper. Margin -792.06%
Profit Margin 0.00%
Shs Outstand 12.38M
Shs Float 7.93M
Insider Own 11.56%
Instit Own 18.86%
Short Float 0.88%
Short Ratio 0.13
Short Interest 103.02K
52W High 2.22
vs 52W High -59.46%
52W Low 0.55
vs 52W Low 64.23%
Beta 1.52
Impl. Vol.
Rel Volume 0.16
Avg Volume 459.17K
Volume 71.61K
Target (mean) $4.40
Tgt Median $5.00
Tgt Low $1.20
Tgt High $7.00
# Analysts 3
Recom None
Prev Close $0.93
Price $0.90
Change -3.26%
About

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.

Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus Mean price target
2. Current target Latest analyst target
3. DCF / Fair value Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$0.90
Low
$1.20
High
$7.00
Mean
$4.40

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-05-07 init Oppenheimer — → Outperform $5
2026-03-31 reit Wedbush Outperform → Outperform $7
2026-03-31 main HC Wainwright & Co. Buy → Buy $1
2026-02-10 main Wedbush Outperform → Outperform $7
2026-01-29 main HC Wainwright & Co. Buy → Buy $4
2025-12-18 main HC Wainwright & Co. Buy → Buy $5
2025-01-15 reit HC Wainwright & Co. Buy → Buy $20
2024-12-17 reit HC Wainwright & Co. Buy → Buy $20
2024-11-18 reit HC Wainwright & Co. Buy → Buy $20
2024-10-24 reit HC Wainwright & Co. Buy → Buy $20
2024-08-13 reit Wedbush Outperform → Outperform $11
2024-08-12 reit HC Wainwright & Co. Buy → Buy $20
2024-06-24 reit HC Wainwright & Co. Buy → Buy $20
2024-06-17 reit HC Wainwright & Co. Buy → Buy $20
2024-05-14 reit HC Wainwright & Co. Buy → Buy $20
2024-03-27 main Wedbush Outperform → Outperform $11
2024-03-26 main HC Wainwright & Co. Buy → Buy $20
2023-11-01 reit HC Wainwright & Co. Buy → Buy $20
2023-09-13 reit HC Wainwright & Co. Buy → Buy $20
2023-08-10 reit HC Wainwright & Co. Buy → Buy $20
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-03-12 HAMILL JOHN P Chief Financial Officer 10,095 $0.00 $0
2026-03-12 GILAD OREN PH.D. Chief Executive Officer 20,175 $0.00 $0
2026-01-30 HAMILL JOHN P Chief Financial Officer 5,700 $0.89 $5,073
2026-01-30 GILAD OREN PH.D. Chief Executive Officer 28,100 $0.89 $25,009
2025-12-10 HAMILL JOHN P Chief Financial Officer 5,000 $0.91 $4,561
2025-12-10 DUEY MARC Director 21,459 $0.91 $19,575
2025-06-05 PAMAKCU RIFAT Director 1,045 $0.00 $0
2025-06-05 HENNEMAN JOHN BELL III Director 1,045 $0.00 $0
2025-06-05 BIZZARI JEAN-PIERRE Director 1,045 $0.00 $0
2025-06-05 PETERS RICHARD Director 1,045 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
13.23
-7.58%
14.32
-7.45%
15.47
-58.60%
37.37
Research And Development
7.04
-24.78%
9.36
+22.76%
7.63
-53.50%
16.40
Selling General And Administration
6.48
+0.28%
6.46
-23.36%
8.43
-59.81%
20.97
General And Administrative Expense
6.48
+0.28%
6.46
-23.36%
8.43
-59.81%
20.97
Other Gand A
6.48
+0.28%
6.46
-23.36%
8.43
-59.81%
20.97
Other Operating Expenses
-0.29
+80.98%
-1.50
-157.63%
-0.58
Total Expenses
13.23
-7.58%
14.32
-7.45%
15.47
-58.60%
37.37
Operating Income
-13.23
+7.58%
-14.32
+7.45%
-15.47
+58.60%
-37.37
Total Operating Income As Reported
-13.23
+7.58%
-14.32
+7.45%
-15.47
+86.36%
-113.39
EBITDA
-13.21
+7.59%
-14.30
+7.55%
-15.46
+58.41%
-37.19
Normalized EBITDA
-13.12
+8.72%
-14.37
+6.85%
-15.43
-140.01%
38.55
Reconciled Depreciation
0.02
-2.70%
0.02
+216.48%
0.01
-96.22%
0.19
EBIT
-13.23
+7.58%
-14.32
+7.45%
-15.47
+58.60%
-37.37
Total Unusual Items
-0.10
-232.76%
0.07
+284.45%
-0.04
+99.95%
-75.74
Total Unusual Items Excluding Goodwill
-0.10
-232.76%
0.07
+284.45%
-0.04
+99.95%
-75.74
Special Income Charges
0.00
+100.00%
-76.02
Other Special Charges
76.02
Net Income
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Pretax Income
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Net Non Operating Interest Income Expense
0.65
-49.42%
1.29
+5.31%
1.22
+172.84%
0.45
Net Interest Income
0.65
-49.42%
1.29
+5.31%
1.22
+172.84%
0.45
Interest Income Non Operating
0.65
-49.42%
1.29
+5.31%
1.22
+172.84%
0.45
Interest Income
0.65
-49.42%
1.29
+5.31%
1.22
+172.84%
0.45
Other Income Expense
-0.02
-124.82%
0.07
+284.45%
-0.04
+99.95%
-75.74
Other Non Operating Income Expenses
0.08
Gain On Sale Of Security
-0.10
-232.76%
0.07
+284.45%
-0.04
-113.83%
0.28
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Net Income From Continuing Operation Net Minority Interest
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Net Income From Continuing And Discontinued Operation
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Net Income Continuous Operations
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Normalized Income
-12.50
+4.04%
-13.03
+8.54%
-14.25
+61.41%
-36.92
Net Income Common Stockholders
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Diluted EPS
-2.35
+40.51%
-3.95
+94.19%
-67.99
Basic EPS
-2.35
+40.51%
-3.95
+94.19%
-67.99
Basic Average Shares
5.51
+52.31%
3.62
+118.32%
1.66
Diluted Average Shares
5.51
+52.31%
3.62
+118.32%
1.66
Diluted NI Availto Com Stockholders
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Total Other Finance Cost
-0.45
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
15.93
-33.55%
23.98
+5.87%
22.65
-24.89%
30.16
Current Assets
15.56
-34.00%
23.58
+4.68%
22.52
-25.31%
30.15
Cash Cash Equivalents And Short Term Investments
14.60
-36.11%
22.85
+5.75%
21.61
-24.94%
28.79
Cash And Cash Equivalents
14.60
-36.11%
22.85
+5.75%
21.61
-24.94%
28.79
Prepaid Assets
Other Current Assets
0.96
+32.45%
0.73
-20.57%
0.91
-33.11%
1.37
Total Non Current Assets
0.37
-7.73%
0.40
+212.49%
0.13
+5461.35%
0.00
Net PPE
0.06
-26.64%
0.08
-7.74%
0.09
+3707.07%
0.00
Gross PPE
0.15
+0.00%
0.15
+11.18%
0.14
+205.09%
0.05
Accumulated Depreciation
-0.09
-29.98%
-0.07
-44.53%
-0.05
-16.37%
-0.04
Machinery Furniture Equipment
0.01
+0.00%
0.01
+0.00%
0.01
+0.00%
0.01
Other Properties
0.15
+0.00%
0.15
+11.62%
0.13
+231.96%
0.04
Other Non Current Assets
0.31
-2.95%
0.32
+690.41%
0.04
Total Liabilities Net Minority Interest
3.49
-25.26%
4.67
-17.99%
5.70
+26.25%
4.51
Current Liabilities
2.76
-17.75%
3.36
-23.36%
4.39
+37.00%
3.20
Payables And Accrued Expenses
1.99
-31.15%
2.90
+1.98%
2.84
+57.49%
1.80
Payables
0.71
-47.22%
1.35
-19.05%
1.67
+98.20%
0.84
Accounts Payable
0.71
-47.22%
1.35
-19.05%
1.67
+98.20%
0.84
Current Accrued Expenses
1.28
-17.08%
1.54
+32.02%
1.17
+21.76%
0.96
Pensionand Other Post Retirement Benefit Plans Current
0.77
+65.71%
0.47
-54.27%
1.02
-27.25%
1.40
Current Debt And Capital Lease Obligation
Current Capital Lease Obligation
0.00
Current Deferred Liabilities
0.00
-100.00%
0.53
0.00
Current Deferred Revenue
0.00
-100.00%
0.53
0.00
Total Non Current Liabilities Net Minority Interest
0.73
-44.52%
1.31
+0.00%
1.31
+0.00%
1.31
Long Term Debt And Capital Lease Obligation
0.00
Long Term Capital Lease Obligation
0.00
Preferred Securities Outside Stock Equity
0.73
-44.52%
1.31
+0.00%
1.31
+0.00%
1.31
Stockholders Equity
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Common Stock Equity
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Capital Stock
0.01
+49.46%
0.01
+46.71%
0.00
+40.72%
0.00
Common Stock
0.01
+49.46%
0.01
+46.71%
0.00
+40.72%
0.00
Share Issued
8.19
+49.47%
5.48
+46.68%
3.74
+40.73%
2.66
Ordinary Shares Number
8.19
+49.47%
5.48
+46.68%
3.74
+40.73%
2.66
Additional Paid In Capital
356.71
+1.64%
350.97
+4.57%
335.64
+1.69%
330.06
Retained Earnings
-333.64
-3.92%
-321.04
-4.21%
-308.08
-4.86%
-293.80
Gains Losses Not Affecting Retained Earnings
-10.63
-0.07%
-10.63
-0.15%
-10.61
+0.11%
-10.62
Other Equity Adjustments
-10.63
-0.07%
-10.63
-0.15%
-10.61
+0.11%
-10.62
Total Equity Gross Minority Interest
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Total Capitalization
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Working Capital
12.80
-36.70%
20.22
+11.47%
18.14
-32.71%
26.95
Invested Capital
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Total Debt
0.00
Capital Lease Obligations
0.00
Net Tangible Assets
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Tangible Book Value
12.44
-35.56%
19.31
+13.88%
16.95
-33.89%
25.64
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-12.89
+4.89%
-13.56
-11.32%
-12.18
+51.31%
-25.01
Cash Flow From Continuing Operating Activities
-12.89
+4.89%
-13.56
-11.32%
-12.18
+51.31%
-25.01
Net Income From Continuing Operations
-12.60
+2.77%
-12.96
+9.30%
-14.29
+87.32%
-112.66
Depreciation Amortization Depletion
0.02
-2.70%
0.02
+216.48%
0.01
-96.22%
0.19
Depreciation
0.01
-96.22%
0.19
Depreciation And Amortization
0.02
-2.70%
0.02
+216.48%
0.01
-96.22%
0.19
Other Non Cash Items
0.04
+123.97%
0.02
72.52
Stock Based Compensation
0.48
-2.31%
0.49
+10.12%
0.44
-97.38%
16.98
Operating Gains Losses
0.10
+232.76%
-0.07
-284.45%
0.04
+113.83%
-0.28
Net Foreign Currency Exchange Gain Loss
0.10
+232.76%
-0.07
-284.45%
0.04
+113.83%
-0.28
Change In Working Capital
-0.93
+11.97%
-1.06
-165.20%
1.62
+192.05%
-1.76
Change In Prepaid Assets
-0.22
-125.40%
-0.10
-121.39%
0.45
-79.36%
2.19
Change In Payables And Accrued Expense
-0.71
-65.49%
-0.43
-167.39%
0.64
+116.95%
-3.76
Change In Accrued Expense
-0.06
+44.19%
-0.12
+39.10%
-0.19
+93.47%
-2.90
Change In Payable
-0.65
-105.82%
-0.31
-137.97%
0.83
+196.38%
-0.86
Change In Account Payable
-0.65
-105.82%
-0.31
-137.97%
0.83
+196.38%
-0.86
Change In Other Working Capital
-0.53
-200.00%
0.53
Change In Other Current Liabilities
0.00
+100.00%
-0.19
Investing Cash Flow
0.00
+100.00%
-0.02
+83.37%
-0.09
0.00
Cash Flow From Continuing Investing Activities
0.00
+100.00%
-0.02
+83.37%
-0.09
0.00
Net PPE Purchase And Sale
0.00
+100.00%
-0.02
+83.37%
-0.09
0.00
Purchase Of PPE
0.00
+100.00%
-0.02
+83.37%
-0.09
0.00
Capital Expenditure
-0.02
+83.37%
-0.09
Financing Cash Flow
4.64
-68.69%
14.82
+188.36%
5.14
+652.59%
0.68
Cash Flow From Continuing Financing Activities
4.64
-68.69%
14.82
+188.36%
5.14
+652.59%
0.68
Net Common Stock Issuance
5.05
-68.73%
16.14
+178.81%
5.79
+747.61%
0.68
Proceeds From Stock Option Exercised
0.00
0.00
0.00
0.00
Net Other Financing Charges
-0.41
+69.10%
-1.32
-103.18%
-0.65
Changes In Cash
-8.25
-760.50%
1.25
+117.53%
-7.13
+70.69%
-24.33
Effect Of Exchange Rate Changes
0.00
+165.16%
-0.01
+14.50%
-0.01
-121.67%
0.04
Beginning Cash Position
22.89
+5.74%
21.65
-24.80%
28.79
-45.76%
53.08
End Cash Position
14.64
-36.04%
22.89
+5.74%
21.65
-24.80%
28.79
Free Cash Flow
-12.89
+4.99%
-13.57
-10.61%
-12.27
+50.94%
-25.01
Common Stock Issuance
5.05
-68.73%
16.14
+178.81%
5.79
+747.61%
0.68
Issuance Of Capital Stock
5.05
-68.73%
16.14
+178.81%
5.79
+747.61%
0.68
Net Preferred Stock Issuance
Preferred Stock Issuance
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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