CSTL Chart
About

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), uveal melanoma, and mental health conditions. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the risk of metastasis for patients with uveal melanoma; DecisionDx-SCC, a risk stratification test for cutaneous squamous cell carcinoma; MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a risk stratification spatial-omics test to predict future development of progression of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma; and IDgenetix, a pharmacogenomic test that helps guide optimal drug treatment for patients diagnosed with major depressive disorder, schizophrenia, bipolar disorder, anxiety disorders, social phobia, obsessive-compulsive personality disorder, post-traumatic stress disorder, and attention deficit hyperactivity disorder. The company offers its products to skin cancer and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Diagnostics & Research Market Cap 873.91M
Enterprise Value 594.32M Income -12.24M Sales 343.53M
Book/sh 16.02 Cash/sh 9.85 Dividend Yield —
Payout 0.00% Employees 823 IPO —
P/E — Forward P/E -23.30 PEG —
P/S 2.54 P/B 1.87 P/C —
EV/EBITDA 75.91 EV/Sales 1.73 Quick Ratio 6.12
Current Ratio 6.46 Debt/Eq 7.95 LT Debt/Eq —
EPS (ttm) -0.44 EPS next Y -1.28 EPS Growth —
Revenue Growth -3.20% Earnings 2026-02-26 ROA -1.72%
ROE -2.70% ROIC — Gross Margin 79.94%
Oper. Margin -8.19% Profit Margin -3.56% Shs Outstand 29.19M
Shs Float 24.57M Short Float 5.94% Short Ratio 4.06
Short Interest — 52W High 44.28 52W Low 14.59
Beta 1.05 Avg Volume 393.82K Volume 526.29K
Target Price $48.12 Recom Strong_buy Prev Close $28.94
Price $29.94 Change 3.46%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$48.13
Mean price target
2. Current target
$29.94
Latest analyst target
3. DCF / Fair value
$17.94
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$29.94
Low
$41.00
High
$52.00
Mean
$48.13

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-26 main Guggenheim Buy → Buy $47
2026-01-12 main Lake Street Buy → Buy $52
2026-01-05 main Guggenheim Buy → Buy $43
2025-12-22 main Canaccord Genuity Buy → Buy $50
2025-12-12 main BTIG Buy → Buy $50
2025-11-05 main BTIG Buy → Buy $38
2025-11-04 main Baird Outperform → Outperform $41
2025-09-09 main Canaccord Genuity Buy → Buy $37
2025-05-21 main Scotiabank Sector Outperform → Sector Outperform $40
2025-05-06 main Lake Street Buy → Buy $35
2025-05-06 main Canaccord Genuity Buy → Buy $37
2025-02-28 main Baird Outperform → Outperform $37
2025-01-02 reit Stephens & Co. Overweight → Overweight $41
2024-11-06 main Scotiabank Sector Outperform → Sector Outperform $44
2024-11-05 main Lake Street Buy → Buy $40
2024-11-05 main Keybanc Overweight → Overweight $36
2024-11-05 main Baird Outperform → Outperform $39
2024-10-29 main Canaccord Genuity Buy → Buy $42
2024-10-14 main BTIG Buy → Buy $40
2024-08-06 reit Stephens & Co. Overweight → Overweight $37
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 4017 158757.0 — Sale at price 37.82 - 39.91 per share. MAETZOLD DEREK J Chief Executive Officer — 2026-02-04 00:00:00 D
1 4017 160732.0 — Sale at price 40.01 per share. MAETZOLD DEREK J Chief Executive Officer — 2026-01-20 00:00:00 D
2 8124 — — Stock Award(Grant) at price 0.00 per share. STOKES FRANKLIN M. Chief Financial Officer — 2026-01-12 00:00:00 D
3 9207 — — Stock Award(Grant) at price 0.00 per share. OELSCHLAGER KRISTEN M Chief Operating Officer — 2026-01-12 00:00:00 D
4 9207 — — Stock Award(Grant) at price 0.00 per share. JUVENAL TOBIN W Officer — 2026-01-12 00:00:00 D
5 62219 — — Stock Award(Grant) at price 0.00 per share. MAETZOLD DEREK J Chief Executive Officer — 2026-01-12 00:00:00 D
6 4017 155694.0 — Sale at price 38.09 - 40.10 per share. MAETZOLD DEREK J Chief Executive Officer — 2026-01-06 00:00:00 D
7 830 33490.0 — Sale at price 40.35 per share. MAETZOLD DEREK J Chief Executive Officer — 2025-12-22 00:00:00 D
8 14888 585292.0 — Sale at price 39.31 per share. OELSCHLAGER KRISTEN M Chief Operating Officer — 2025-12-17 00:00:00 D
9 509 20380.0 — Sale at price 40.04 per share. MAETZOLD DEREK J Chief Executive Officer — 2025-12-17 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.00468.69K0.00
TaxRateForCalcs0.150.210.030.22
NormalizedEBITDA38.14M-45.02M-76.63M-36.60M
TotalUnusualItems0.000.0018.29M0.00
TotalUnusualItemsExcludingGoodwill0.000.0018.29M0.00
NetIncomeFromContinuingOperationNetMinorityInterest18.25M-57.47M-67.14M-31.29M
ReconciledDepreciation16.00M12.33M10.54M3.41M
ReconciledCostOfRevenue55.31M41.66M29.73M14.37M
EBITDA38.14M-45.02M-58.34M-36.60M
EBIT22.14M-57.35M-68.89M-40.01M
NetInterestIncome12.34M10.61M3.95M67.00K
InterestExpense577.00K11.00K17.00K1.00K
InterestIncome12.92M10.62M3.97M68.00K
NormalizedIncome18.25M-57.47M-84.96M-31.29M
NetIncomeFromContinuingAndDiscontinuedOperation18.25M-57.47M-67.14M-31.29M
TotalExpenses323.40M287.76M228.18M134.16M
TotalOperatingIncomeAsReported8.67M-67.98M-72.86M-40.08M
DilutedAverageShares29.25M26.80M26.05M25.14M
BasicAverageShares27.78M26.80M26.05M25.14M
DilutedEPS0.62-2.14-2.58-1.24
BasicEPS0.66-2.14-2.58-1.24
DilutedNIAvailtoComStockholders18.25M-57.47M-67.14M-31.29M
NetIncomeCommonStockholders18.25M-57.47M-67.14M-31.29M
NetIncome18.25M-57.47M-67.14M-31.29M
NetIncomeIncludingNoncontrollingInterests18.25M-57.47M-67.14M-31.29M
NetIncomeContinuousOperations18.25M-57.47M-67.14M-31.29M
TaxProvision3.32M101.00K-1.77M-8.72M
PretaxIncome21.56M-57.37M-68.90M-40.01M
OtherIncomeExpense555.00K18.29M
OtherNonOperatingIncomeExpenses555.00K
SpecialIncomeCharges0.000.0018.29M0.00
RestructuringAndMergernAcquisition0.000.00-18.29M0.00
NetNonOperatingInterestIncomeExpense12.34M10.61M3.95M67.00K
InterestExpenseNonOperating577.00K11.00K17.00K1.00K
InterestIncomeNonOperating12.92M10.62M3.97M68.00K
OperatingIncome8.67M-67.98M-91.14M-40.08M
OperatingExpense263.19M242.78M196.17M118.34M
DepreciationAmortizationDepletionIncomeStatement11.11M9.01M8.27M1.96M
DepreciationAndAmortizationInIncomeStatement11.11M9.01M8.27M1.96M
Amortization11.11M9.01M8.27M1.96M
AmortizationOfIntangiblesIncomeStatement11.11M9.01M8.27M1.96M
ResearchAndDevelopment52.04M53.62M44.90M29.65M
SellingGeneralAndAdministration200.05M180.15M143.00M86.74M
SellingAndMarketingExpense123.47M113.66M86.61M
GeneralAndAdministrativeExpense76.58M66.50M56.40M
OtherGandA76.58M66.50M56.40M
GrossProfit271.86M174.81M105.03M78.26M
CostOfRevenue60.20M44.98M32.01M15.82M
TotalRevenue332.07M219.79M137.04M94.08M
OperatingRevenue332.07M219.79M137.04M94.08M
Line Item2024-12-312023-12-312022-12-312021-12-31
OrdinarySharesNumber28.48M27.41M26.55M25.38M
ShareIssued28.48M27.41M26.55M25.38M
TotalDebt26.34M15.34M13.40M8.20M
TangibleBookValue349.61M273.93M272.80M322.82M
InvestedCapital465.86M391.27M399.15M411.74M
WorkingCapital310.76M247.97M256.16M328.86M
NetTangibleAssets349.61M273.93M272.80M322.82M
CapitalLeaseObligations16.32M15.34M13.40M8.20M
CommonStockEquity455.83M391.27M399.15M411.74M
TotalCapitalization465.58M391.27M399.15M411.74M
TotalEquityGrossMinorityInterest455.83M391.27M399.15M411.74M
StockholdersEquity455.83M391.27M399.15M411.74M
GainsLossesNotAffectingRetainedEarnings230.00K136.00K-381.00K0.00
OtherEquityAdjustments230.00K136.00K-381.00K
RetainedEarnings-200.13M-218.37M-160.91M-93.77M
AdditionalPaidInCapital655.70M609.48M560.41M505.48M
CapitalStock28.00K27.00K27.00K25.00K
CommonStock28.00K27.00K27.00K25.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest75.40M62.07M48.18M50.83M
TotalNonCurrentLiabilitiesNetMinorityInterest26.01M14.40M12.05M25.95M
OtherNonCurrentLiabilities18.29M
NonCurrentDeferredLiabilities1.61M206.00K428.00K635.00K
NonCurrentDeferredRevenue0.00
NonCurrentDeferredTaxesLiabilities1.61M206.00K428.00K635.00K
LongTermDebtAndCapitalLeaseObligation24.40M14.20M11.62M7.02M
LongTermCapitalLeaseObligation14.66M14.20M11.62M7.02M
LongTermDebt9.74M
CurrentLiabilities49.39M47.67M36.13M24.89M
OtherCurrentLiabilities774.00K606.00K415.00K663.00K
CurrentDeferredLiabilities0.00
CurrentDeferredRevenue0.00
CurrentDebtAndCapitalLeaseObligation1.94M1.14M1.78M1.18M
CurrentCapitalLeaseObligation1.67M1.14M1.78M1.18M
CurrentDebt278.00K
OtherCurrentBorrowings278.00K
PensionandOtherPostRetirementBenefitPlansCurrent33.78M29.84M25.26M16.24M
PayablesAndAccruedExpenses12.89M16.08M8.68M6.80M
CurrentAccruedExpenses4.92M5.41M3.95M4.25M
Payables7.98M10.67M4.73M2.55M
TotalTaxPayable1.08M401.00K37.00K695.00K
AccountsPayable6.90M10.27M4.73M2.55M
TotalAssets531.24M453.34M447.33M462.57M
TotalNonCurrentAssets171.08M157.71M155.04M108.83M
OtherNonCurrentAssets1.23M1.44M1.11M1.72M
NonCurrentAccountsReceivable918.00K1.19M1.09M1.31M
GoodwillAndOtherIntangibleAssets106.23M117.33M126.35M88.92M
OtherIntangibleAssets95.54M106.64M115.66M88.92M
Goodwill10.69M10.69M10.69M0.00
NetPPE62.71M37.74M26.50M16.88M
AccumulatedDepreciation-12.83M-8.11M-7.85M-3.04M
GrossPPE75.54M45.85M34.34M19.93M
Leases14.62M9.99M5.17M5.04M
ConstructionInProgress9.61M637.00K1.27M27.00K
OtherProperties35.22M28.78M21.90M11.11M
MachineryFurnitureEquipment8.85M6.45M6.00M3.75M
LandAndImprovements7.25M0.00
Properties0.000.000.000.00
CurrentAssets360.15M295.63M292.29M353.74M
OtherCurrentAssets7.67M6.29M6.21M4.81M
PrepaidAssets4.81M
Inventory8.13M7.94M3.98M2.02M
Receivables51.22M38.30M23.48M17.28M
AccountsReceivable51.22M38.30M23.48M17.28M
CashCashEquivalentsAndShortTermInvestments293.13M243.10M258.62M329.63M
OtherShortTermInvestments173.42M144.26M135.68M0.00
CashAndCashEquivalents119.71M98.84M122.95M329.63M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow36.54M-19.25M-47.29M-22.47M
RepaymentOfDebt-97.00K-142.00K-122.00K-8.00K
IssuanceOfDebt10.00M0.000.00
IssuanceOfCapitalStock0.00
CapitalExpenditure-28.33M-13.62M-5.63M-3.48M
InterestPaidSupplementalData434.00K11.00K16.00K1.00K
IncomeTaxPaidSupplementalData2.50M198.00K120.00K16.00K
EndCashPosition119.71M98.84M122.95M329.63M
BeginningCashPosition98.84M122.95M329.63M409.85M
ChangesInCash20.87M-24.11M-206.69M-80.22M
FinancingCashFlow6.14M-2.30M1.51M5.42M
CashFlowFromContinuingFinancingActivities6.14M-2.30M1.51M5.42M
NetOtherFinancingCharges-8.76M-5.13M-1.69M-1.12M
ProceedsFromStockOptionExercised5.00M2.98M3.33M6.55M
NetCommonStockIssuance0.00
CommonStockIssuance0.00
NetIssuancePaymentsOfDebt9.90M-142.00K-122.00K-8.00K
NetLongTermDebtIssuance9.90M-142.00K-122.00K-8.00K
LongTermDebtPayments-97.00K-142.00K-122.00K-8.00K
LongTermDebtIssuance10.00M0.000.00
InvestingCashFlow-50.14M-16.18M-166.54M-66.66M
CashFlowFromContinuingInvestingActivities-50.14M-16.18M-166.54M-66.66M
NetOtherInvestingChanges547.00K-63.18M
NetInvestmentPurchaseAndSale-21.83M-2.58M-134.69M0.00
SaleOfInvestment183.90M186.50M0.00
PurchaseOfInvestment-205.73M-189.07M-134.69M0.00
NetBusinessPurchaseAndSale0.000.00-26.97M0.00
PurchaseOfBusiness0.000.00-26.97M0.00
NetPPEPurchaseAndSale-28.31M-13.61M-5.44M-3.47M
SaleOfPPE18.00K13.00K195.00K10.00K
PurchaseOfPPE-28.33M-13.62M-5.63M-3.48M
OperatingCashFlow64.87M-5.63M-41.66M-18.98M
CashFlowFromContinuingOperatingActivities64.87M-5.63M-41.66M-18.98M
ChangeInWorkingCapital-14.12M-6.63M-7.00K-4.10M
ChangeInOtherWorkingCapital4.59M8.49M6.21M
ChangeInOtherCurrentLiabilities-1.29M852.00K-608.00K-1.13M
ChangeInOtherCurrentAssets1.58M-588.00K1.61M751.00K
ChangeInPayablesAndAccruedExpense-442.00K12.43M8.11M8.31M
ChangeInAccruedExpense3.93M6.73M7.53M8.49M
ChangeInPayable-4.37M5.71M582.00K-182.00K
ChangeInAccountPayable-4.37M5.71M582.00K-182.00K
ChangeInPrepaidAssets-1.14M-435.00K-1.22M-7.73M
ChangeInInventory-193.00K-3.96M-1.68M327.00K
ChangeInReceivables-12.64M-14.93M-6.22M-4.63M
ChangesInAccountReceivables-12.64M-14.93M-6.22M-4.63M
OtherNonCashItems268.00K635.00K-18.13M
StockBasedCompensation50.32M51.22M36.32M21.74M
AmortizationOfSecurities-6.68M-5.49M-1.37M0.00
DeferredTax1.40M-223.00K-1.88M-8.74M
DeferredIncomeTax1.40M-223.00K-1.88M-8.74M
DepreciationAmortizationDepletion16.00M12.33M10.54M3.41M
DepreciationAndAmortization16.00M12.33M10.54M3.41M
AmortizationCashFlow11.11M9.01M8.27M1.96M
AmortizationOfIntangibles11.11M9.01M8.27M1.96M
Depreciation4.89M3.32M2.28M1.45M
OperatingGainsLosses-555.00K
GainLossOnInvestmentSecurities-555.00K
NetIncomeFromContinuingOperations18.25M-57.47M-67.14M-31.29M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for CSTL
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