DTIL Chart
About

Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-3243 for the treatment of m.3243 associated mitochondrial myopathy. In addition, the company develops PBGENE-NVS (insertion) for sickle cell and beta thalassemia diseases; PBGENE-DMD (excision) for duchenne muscular dystrophy; PBGENE-LIVER (insertion), a liver directed target; PBGENE-CNS (excision), a central nervous system directed target; and iECURE-OTC (insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with Novartis Pharma AG to discover and develop in vivo gene editing products; TG Cell Therapy, Inc. to develop, manufacture, and commercialize azer-cel for autoimmune diseases and other indications outside of cancer; and iECURE, Inc. to develop ARCUS-based gene-insertion therapies. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 96.29M
Enterprise Value 37.29M Income -83.60M Sales 698.00K
Book/sh 1.38 Cash/sh 3.38 Dividend Yield —
Payout 0.00% Employees 67 IPO —
P/E — Forward P/E -1.29 PEG —
P/S 137.95 P/B 2.90 P/C —
EV/EBITDA -0.42 EV/Sales 53.42 Quick Ratio 2.99
Current Ratio 3.45 Debt/Eq 175.11 LT Debt/Eq —
EPS (ttm) -8.96 EPS next Y -3.11 EPS Growth —
Revenue Growth -97.70% Earnings 2026-03-31 ROA -45.34%
ROE -205.16% ROIC — Gross Margin 100.00%
Oper. Margin -1589.77% Profit Margin 0.00% Shs Outstand 24.07M
Shs Float 10.17M Short Float 5.81% Short Ratio 5.67
Short Interest — 52W High 8.82 52W Low 3.53
Beta 1.31 Avg Volume 218.70K Volume 93.48K
Target Price $32.50 Recom None Prev Close $3.95
Price $4.00 Change 1.27%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$32.50
Mean price target
2. Current target
$4.00
Latest analyst target
3. DCF / Fair value
$-27.98
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$4.00
Low
$19.00
High
$60.00
Mean
$32.50

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-05-21 reit HC Wainwright & Co. Buy → Buy $60
2025-03-28 reit HC Wainwright & Co. Buy → Buy $60
2025-03-19 reit HC Wainwright & Co. Buy → Buy $60
2025-02-19 reit HC Wainwright & Co. Buy → Buy $60
2025-01-10 reit HC Wainwright & Co. Buy → Buy $60
2025-01-10 up BMO Capital Market Perform → Outperform $34
2024-05-30 reit HC Wainwright & Co. Buy → Buy $60
2024-05-16 reit HC Wainwright & Co. Buy → Buy $60
2024-04-30 init Guggenheim — → Buy $19
2024-04-17 reit HC Wainwright & Co. Buy → Buy $60
2024-03-28 main HC Wainwright & Co. Buy → Buy $60
2024-02-14 reit HC Wainwright & Co. Buy → Buy $3
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 4925 18912.0 — Sale at price 3.84 per share. SMITH J JEFFERSON Officer — 2026-02-18 00:00:00 D
1 4925 18912.0 — Sale at price 3.84 per share. SCIMECA DARIO JOSEPH General Counsel — 2026-02-18 00:00:00 D
2 20559 78947.0 — Sale at price 3.84 per share. AMOROSO MICHAEL Chief Executive Officer — 2026-02-18 00:00:00 D
3 8149 31292.0 — Sale at price 3.84 per share. KELLY JOHN ALEXANDER Chief Financial Officer — 2026-02-18 00:00:00 D
4 16667 nan — — SMITH J JEFFERSON Officer — 2026-02-17 00:00:00 D
5 16667 nan — — SCIMECA DARIO JOSEPH General Counsel — 2026-02-17 00:00:00 D
6 67797 nan — — AMOROSO MICHAEL Chief Executive Officer — 2026-02-17 00:00:00 D
7 27584 nan — — KELLY JOHN ALEXANDER Chief Financial Officer — 2026-02-17 00:00:00 D
8 34799 145112.0 — Sale at price 4.17 per share. AMOROSO MICHAEL Chief Executive Officer — 2026-01-22 00:00:00 D
9 10200 41106.0 — Sale at price 4.03 per share. SMITH J JEFFERSON Officer — 2026-01-21 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-15.65M-31.58M-51.41M-28.79M
TotalUnusualItems29.17M-461.00K-11.38M8.51M
TotalUnusualItemsExcludingGoodwill29.17M-461.00K-11.38M8.51M
NetIncomeFromContinuingOperationNetMinorityInterest7.17M-42.53M-72.91M-30.60M
ReconciledDepreciation4.58M8.26M9.00M10.20M
EBITDA13.53M-32.04M-62.79M-20.27M
EBIT8.95M-40.30M-71.80M-30.47M
NetInterestIncome4.98M5.46M2.36M76.00K
InterestExpense1.78M2.23M1.11M132.00K
InterestIncome6.76M7.69M3.47M208.00K
NormalizedIncome-22.01M-42.07M-61.52M-39.12M
NetIncomeFromContinuingAndDiscontinuedOperation7.17M-61.32M-111.64M-30.60M
TotalExpenses94.86M92.46M87.41M154.91M
TotalOperatingIncomeAsReported-26.16M-43.74M-62.31M-39.38M
DilutedAverageShares6.88M3.84M2.93M1.96M
BasicAverageShares6.83M3.84M2.93M1.96M
DilutedEPS1.04-15.96-38.10-15.60
BasicEPS1.05-15.96-38.10-15.60
DilutedNIAvailtoComStockholders7.17M-61.32M-111.64M-30.60M
NetIncomeCommonStockholders7.17M-61.32M-111.64M-30.60M
NetIncome7.17M-61.32M-111.64M-30.60M
NetIncomeIncludingNoncontrollingInterests7.17M-61.32M-111.64M-30.60M
NetIncomeDiscontinuousOperations0.00-18.79M-38.73M
NetIncomeContinuousOperations7.17M-42.53M-72.91M-30.60M
PretaxIncome7.17M-42.53M-72.91M-30.60M
OtherIncomeExpense28.35M-4.25M-12.96M8.70M
OtherNonOperatingIncomeExpenses258.00K1.15M
SpecialIncomeCharges-436.00K-461.00K-10.87M5.96M
GainOnSaleOfPPE-436.00K-461.00K-30.00K-26.00K
GainOnSaleOfBusiness0.005.99M
WriteOff0.0010.84M0.00
EarningsFromEquityInterest-1.08M-4.93M-1.58M184.00K
GainOnSaleOfSecurity29.61M1.15M-510.00K2.56M
NetNonOperatingInterestIncomeExpense4.98M5.46M2.36M76.00K
InterestExpenseNonOperating1.78M2.23M1.11M132.00K
InterestIncomeNonOperating6.76M7.69M3.47M208.00K
OperatingIncome-26.16M-43.74M-62.31M-39.38M
OperatingExpense94.86M92.46M87.41M154.91M
ResearchAndDevelopment59.56M53.38M46.12M115.24M
SellingGeneralAndAdministration35.30M39.09M41.28M39.67M
GeneralAndAdministrativeExpense35.30M39.09M41.28M39.67M
OtherGandA35.30M39.09M41.28M39.67M
TotalRevenue68.70M48.73M25.10M115.53M
OperatingRevenue68.70M48.73M25.10M115.53M
Line Item2024-12-312023-12-312022-12-312021-12-31
TreasurySharesNumber27.02K27.01K27.02K27.02K
OrdinarySharesNumber8.20M4.16M3.70M2.03M
ShareIssued8.23M4.19M3.73M2.06M
TotalDebt30.05M31.27M24.96M9.11M
TangibleBookValue55.77M18.46M59.70M89.12M
InvestedCapital78.71M41.27M82.66M93.65M
WorkingCapital80.01M86.37M139.44M125.77M
NetTangibleAssets55.77M18.46M59.70M89.12M
CapitalLeaseObligations7.72M8.86M2.74M6.63M
CommonStockEquity56.39M18.86M60.43M91.17M
TotalCapitalization78.71M18.86M82.66M93.65M
TotalEquityGrossMinorityInterest56.39M18.86M60.43M91.17M
StockholdersEquity56.39M18.86M60.43M91.17M
TreasuryStock952.00K952.00K952.00K952.00K
RetainedEarnings-482.46M-489.63M-428.31M-316.68M
AdditionalPaidInCapital539.81M509.44M489.70M408.80M
CapitalStock1.00K1.00K1.00K0.00
CommonStock1.00K1.00K1.00K0.00
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest80.00M140.92M177.74M120.33M
TotalNonCurrentLiabilitiesNetMinorityInterest65.02M90.93M118.07M84.35M
OtherNonCurrentLiabilities194.00K128.00K201.00K44.00K
LiabilitiesHeldforSaleNonCurrent128.00K1.72M
DerivativeProductLiabilities2.80M0.00
NonCurrentDeferredLiabilities33.30M83.08M92.87M77.02M
NonCurrentDeferredRevenue33.30M83.08M92.87M77.02M
LongTermDebtAndCapitalLeaseObligation28.73M7.72M23.28M7.29M
LongTermCapitalLeaseObligation6.40M7.72M1.06M4.81M
LongTermDebt22.32M22.22M2.48M
CurrentLiabilities14.98M49.99M59.66M35.98M
OtherCurrentLiabilities2.19M4.90M4.21M977.00K
CurrentDeferredLiabilities2.96M12.04M46.19M21.24M
CurrentDeferredRevenue2.96M12.04M46.19M21.24M
CurrentDebtAndCapitalLeaseObligation1.32M23.55M1.68M1.82M
CurrentCapitalLeaseObligation1.32M1.13M1.68M1.82M
CurrentDebt22.41M
OtherCurrentBorrowings22.41M
PensionandOtherPostRetirementBenefitPlansCurrent5.18M4.98M5.10M6.76M
PayablesAndAccruedExpenses3.33M4.53M2.48M5.17M
CurrentAccruedExpenses2.02M1.56M1.83M4.03M
Payables1.31M2.97M653.00K1.14M
AccountsPayable1.31M2.97M653.00K1.14M
TotalAssets136.39M159.78M238.17M211.50M
TotalNonCurrentAssets41.40M23.42M39.06M49.74M
OtherNonCurrentAssets22.79M225.00K12.57M4.64M
NonCurrentNoteReceivables4.60M4.99M7.23M6.88M
InvestmentsAndAdvances3.21M3.21M4.75M6.84M
InvestmentinFinancialAssets3.21M3.21M2.58M3.09M
AvailableForSaleSecurities3.21M3.21M2.58M3.09M
LongTermEquityInvestment0.002.17M3.75M
InvestmentsInOtherVenturesUnderEquityMethod3.75M
GoodwillAndOtherIntangibleAssets622.00K400.00K731.00K2.05M
OtherIntangibleAssets622.00K400.00K731.00K2.05M
NetPPE10.18M14.60M13.78M29.33M
AccumulatedDepreciation-28.08M-25.49M-21.87M-23.91M
GrossPPE38.26M40.09M35.65M53.25M
Leases12.03M11.95M11.95M22.78M
ConstructionInProgress9.00K70.00K520.00K3.04M
OtherProperties22.18M24.12M19.23M23.47M
MachineryFurnitureEquipment4.04M3.96M3.95M3.95M
Properties0.000.000.000.00
CurrentAssets94.99M136.36M199.10M161.75M
OtherCurrentAssets369.00K419.00K1.23M169.00K
AssetsHeldForSaleCurrent169.00K487.00K1.56M
PrepaidAssets6.44M5.98M6.03M17.43M
Receivables1.70M12.80M720.00K488.00K
OtherReceivables1.47M
NotesReceivable0.0011.90M0.00
AccountsReceivable229.00K901.00K720.00K488.00K
CashCashEquivalentsAndShortTermInvestments86.31M116.68M189.58M143.66M
OtherShortTermInvestments413.00K0.00
CashAndCashEquivalents85.90M116.68M189.58M143.66M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-58.72M-86.39M-49.07M-16.66M
RepaymentOfDebt-22.50M0.000.00-2.50M
IssuanceOfDebt22.47M0.0019.80M4.97M
IssuanceOfCapitalStock50.24M4.99M74.34M60.48M
CapitalExpenditure-275.00K-2.28M-3.32M-5.80M
InterestPaidSupplementalData1.74M2.02M824.00K68.00K
EndCashPosition108.47M116.68M189.58M143.66M
BeginningCashPosition116.68M189.58M143.66M89.80M
ChangesInCash-8.21M-72.90M45.91M53.87M
FinancingCashFlow50.45M5.39M94.98M70.52M
CashFlowFromContinuingFinancingActivities50.45M5.39M94.98M70.52M
NetOtherFinancingCharges-13.00K
ProceedsFromStockOptionExercised249.00K401.00K835.00K7.59M
NetCommonStockIssuance50.24M4.99M74.34M60.48M
CommonStockIssuance50.24M4.99M74.34M60.48M
NetIssuancePaymentsOfDebt-37.00K0.0019.80M2.47M
NetShortTermDebtIssuance0.0019.80M2.50M
ShortTermDebtIssuance0.0019.80M2.50M
NetLongTermDebtIssuance-37.00K0.000.00-35.00K
LongTermDebtPayments-22.50M0.000.00-2.50M
LongTermDebtIssuance22.47M0.000.002.46M
InvestingCashFlow-215.00K5.83M-3.32M-5.80M
CashFlowFromContinuingInvestingActivities-215.00K5.83M-3.32M-5.80M
NetBusinessPurchaseAndSale0.008.00M0.00
SaleOfBusiness0.008.00M0.00
NetIntangiblesPurchaseAndSale-25.00K-321.00K0.00-750.00K
PurchaseOfIntangibles-25.00K-321.00K0.00-750.00K
NetPPEPurchaseAndSale-190.00K-1.85M-3.32M-5.05M
SaleOfPPE60.00K107.00K0.00
PurchaseOfPPE-250.00K-1.96M-3.32M-5.05M
OperatingCashFlow-58.45M-84.11M-45.75M-10.85M
CashFlowFromContinuingOperatingActivities-58.45M-84.11M-45.75M-10.85M
ChangeInWorkingCapital-54.00M-41.49M24.11M19.58M
ChangeInOtherWorkingCapital-56.87M-43.95M27.36M6.84M
ChangeInOtherCurrentLiabilities-3.26M-1.67M-3.64M-513.00K
ChangeInOtherCurrentAssets-262.00K1.75M1.43M-2.73M
ChangeInPayablesAndAccruedExpense-2.10M1.51M153.00K867.00K
ChangeInPayable-2.10M1.51M153.00K867.00K
ChangeInAccountPayable-2.10M1.51M153.00K867.00K
ChangeInPrepaidAssets-464.00K1.05M-962.00K5.62M
ChangeInReceivables8.95M-181.00K-232.00K9.51M
ChangesInAccountReceivables672.00K-181.00K-232.00K9.51M
OtherNonCashItems-446.00K-147.00K450.00K-20.40M
StockBasedCompensation12.60M14.04M19.20M16.51M
UnrealizedGainLossOnInvestmentSecurities-258.00K-1.15M
AssetImpairmentCharge0.00641.00K11.44M0.00
DepreciationAmortizationDepletion4.58M8.26M9.00M10.20M
DepreciationAndAmortization4.58M8.26M9.00M10.20M
Depreciation4.58M8.26M9.00M10.20M
OperatingGainsLosses-28.09M-2.95M1.69M-6.14M
EarningsLossesFromEquityInvestments1.08M4.93M1.58M-184.00K
GainLossOnInvestmentSecurities-29.61M
GainLossOnSaleOfBusiness0.00-8.45M0.00-5.99M
NetIncomeFromContinuingOperations7.17M-61.32M-111.64M-30.60M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for DTIL
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