MGTX Chart
About

MeiraGTx Holdings plc, a clinical stage genetics medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also developing AAV-AQP1 in Phase 2 trial for radiation-induced grade 2/3 radiation-induced xerostomia, as well as in Phase ½ trial for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase 2 trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 633.87M
Enterprise Value 693.00M Income -168.69M Sales 27.42M
Book/sh -0.50 Cash/sh 0.18 Dividend Yield —
Payout 0.00% Employees 409 IPO —
P/E — Forward P/E -3.14 PEG —
P/S 23.12 P/B -15.62 P/C —
EV/EBITDA -4.58 EV/Sales 25.28 Quick Ratio 0.17
Current Ratio 0.22 Debt/Eq — LT Debt/Eq —
EPS (ttm) -2.11 EPS next Y -2.51 EPS Growth —
Revenue Growth -96.20% Earnings 2026-03-12 ROA -41.91%
ROE -6.11% ROIC — Gross Margin 41.01%
Oper. Margin -112.32% Profit Margin 0.00% Shs Outstand 80.49M
Shs Float 41.37M Short Float 10.50% Short Ratio 13.07
Short Interest — 52W High 9.73 52W Low 4.55
Beta 1.38 Avg Volume 472.11K Volume 95.11K
Target Price $26.75 Recom None Prev Close $7.70
Price $7.88 Change 2.27%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$26.75
Mean price target
2. Current target
$7.88
Latest analyst target
3. DCF / Fair value
$-13.61
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$7.88
Low
$14.00
High
$50.00
Mean
$26.75

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-11-24 init HC Wainwright & Co. — → Buy $20
2025-11-14 main RBC Capital Outperform → Outperform $16
2025-11-14 main Chardan Capital Buy → Buy $35
2025-11-11 main Piper Sandler Overweight → Overweight $30
2025-11-11 main Chardan Capital Buy → Buy $35
2025-10-21 init Raymond James — → Strong Buy $29
2025-08-15 main Chardan Capital Buy → Buy $35
2025-05-14 main Chardan Capital Buy → Buy $35
2025-03-17 main RBC Capital Outperform → Outperform $13
2025-02-24 main Chardan Capital Buy → Buy $36
2024-11-18 main Chardan Capital Buy → Buy $36
2024-11-14 main RBC Capital Outperform → Outperform $11
2024-08-13 main RBC Capital Outperform → Outperform $9
2024-07-31 main Chardan Capital Buy → Buy $36
2024-03-15 reit RBC Capital Outperform → Outperform $11
2023-08-11 main RBC Capital Outperform → Outperform $11
2023-08-11 reit Chardan Capital Buy → Buy $41
2023-05-12 main Piper Sandler Overweight → Overweight $25
2023-03-16 main Chardan Capital — → Buy $41
2023-03-15 main RBC Capital — → Outperform $22
Insider Transactions
Date Shares Url Text Insider Position Transaction Start Date Ownership Value
0 62500 — — FORBES ALEXANDRIA Chief Executive Officer — 2026-02-20 00:00:00 D nan
1 7500 — — ZELDIN ROBERT K Officer — 2026-02-20 00:00:00 D nan
2 60000 — — GIROUX RICHARD Chief Operating Officer — 2026-02-20 00:00:00 D nan
3 25000 — — NAYLOR STUART Officer — 2026-02-20 00:00:00 D nan
4 11250 — — WOLLIN ROBERT J General Counsel — 2026-02-20 00:00:00 D nan
5 310000 — — FORBES ALEXANDRIA Chief Executive Officer — 2026-01-16 00:00:00 D nan
6 35000 — — ZELDIN ROBERT K Officer — 2026-01-16 00:00:00 D nan
7 310000 — — GIROUX RICHARD Chief Operating Officer — 2026-01-16 00:00:00 D nan
8 75000 — — NAYLOR STUART Officer — 2026-01-16 00:00:00 D nan
9 50000 — — WOLLIN ROBERT J General Counsel — 2026-01-16 00:00:00 D nan
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-147.39M-120.57M-106.97M-64.67M
TotalUnusualItems25.55M63.51M-9.09M-6.73M
TotalUnusualItemsExcludingGoodwill25.55M63.51M-9.09M-6.73M
NetIncomeFromContinuingOperationNetMinorityInterest-147.79M-84.03M-129.62M-79.56M
ReconciledDepreciation12.68M13.72M8.60M7.87M
ReconciledCostOfRevenue23.79M0.00
EBITDA-121.84M-57.06M-116.07M-71.40M
EBIT-134.52M-70.78M-124.67M-79.27M
NetInterestIncome-9.13M-10.97M-4.17M-76.00K
InterestExpense13.27M13.24M4.95M288.00K
InterestIncome4.14M2.27M777.00K212.00K
NormalizedIncome-173.34M-147.53M-120.52M-72.83M
NetIncomeFromContinuingAndDiscontinuedOperation-147.79M-84.03M-129.62M-79.56M
TotalExpenses197.49M151.08M132.28M110.46M
TotalOperatingIncomeAsReported-164.21M-137.06M-116.36M-72.76M
DilutedAverageShares69.82M56.49M45.18M44.14M
BasicAverageShares69.82M56.49M45.18M44.14M
DilutedEPS-2.12-1.49-2.87-1.80
BasicEPS-2.12-1.49-2.87-1.80
DilutedNIAvailtoComStockholders-147.79M-84.03M-129.62M-79.56M
NetIncomeCommonStockholders-147.79M-84.03M-129.62M-79.56M
NetIncome-147.79M-84.03M-129.62M-79.56M
NetIncomeIncludingNoncontrollingInterests-147.79M-84.03M-129.62M-79.56M
NetIncomeContinuousOperations-147.79M-84.03M-129.62M-79.56M
PretaxIncome-147.79M-84.03M-129.62M-79.56M
OtherIncomeExpense25.55M64.01M-9.09M-6.73M
OtherNonOperatingIncomeExpenses499.00K361.00K-434.00K
SpecialIncomeCharges28.43M54.21M0.00
GainOnSaleOfPPE28.43M54.21M0.00
GainOnSaleOfSecurity-2.89M9.30M-9.09M-6.73M
NetNonOperatingInterestIncomeExpense-9.13M-10.97M-4.17M-76.00K
InterestExpenseNonOperating13.27M13.24M4.95M288.00K
InterestIncomeNonOperating4.14M2.27M777.00K212.00K
OperatingIncome-164.21M-137.06M-116.36M-72.76M
OperatingExpense173.70M151.08M132.28M110.46M
ResearchAndDevelopment119.48M103.78M85.72M66.69M
SellingGeneralAndAdministration54.22M47.29M46.55M43.77M
GeneralAndAdministrativeExpense54.22M47.29M46.55M43.77M
OtherGandA54.22M47.29M46.55M43.77M
GrossProfit9.49M14.02M
CostOfRevenue23.79M0.00
TotalRevenue33.28M14.02M15.92M37.70M
OperatingRevenue33.28M14.02M15.92M37.70M
Line Item2023-12-31
TreasurySharesNumber0.00
OrdinarySharesNumber78.40M63.60M48.48M44.55M
ShareIssued78.40M63.60M48.48M44.55M
TotalDebt84.80M89.26M92.25M23.73M
TangibleBookValue67.01M137.06M115.66M182.83M
InvestedCapital141.05M210.30M188.77M185.40M
WorkingCapital62.73M92.54M72.27M115.11M
NetTangibleAssets67.01M137.06M115.66M182.83M
CapitalLeaseObligations11.58M17.14M21.21M23.73M
CommonStockEquity67.83M138.18M117.74M185.40M
TotalCapitalization141.05M210.30M188.77M185.40M
TotalEquityGrossMinorityInterest67.83M138.18M117.74M185.40M
StockholdersEquity67.83M138.18M117.74M185.40M
GainsLossesNotAffectingRetainedEarnings-3.72M-1.44M6.05M-2.67M
OtherEquityAdjustments-3.72M-1.44M6.05M-2.67M
RetainedEarnings-702.02M-554.23M-470.20M-340.59M
AdditionalPaidInCapital773.57M693.84M581.89M528.66M
CapitalStock3.00K2.00K2.00K2.00K
CommonStock3.00K2.00K2.00K2.00K
TotalLiabilitiesNetMinorityInterest201.92M188.57M200.50M134.76M
TotalNonCurrentLiabilitiesNetMinorityInterest141.14M121.49M118.43M66.64M
OtherNonCurrentLiabilities262.00K953.00K
NonCurrentDeferredLiabilities57.58M34.02M27.62M43.24M
NonCurrentDeferredRevenue57.58M34.02M27.44M43.05M
NonCurrentDeferredTaxesLiabilities0.00186.00K196.00K
LongTermDebtAndCapitalLeaseObligation80.74M85.07M88.36M20.36M
LongTermCapitalLeaseObligation7.52M12.95M17.33M20.36M
LongTermDebt73.22M72.12M71.03M
LongTermProvisions2.82M2.40M2.18M2.08M
CurrentLiabilities60.78M67.08M82.07M68.13M
OtherCurrentLiabilities903.00K1.28M6.63M
CurrentDeferredLiabilities4.83M2.93M15.12M21.82M
CurrentDeferredRevenue4.83M2.93M15.12M21.82M
CurrentDebtAndCapitalLeaseObligation4.05M4.19M3.88M3.37M
CurrentCapitalLeaseObligation4.05M4.19M3.88M3.37M
PensionandOtherPostRetirementBenefitPlansCurrent11.20M12.13M9.60M6.03M
PayablesAndAccruedExpenses39.80M46.55M46.83M36.91M
CurrentAccruedExpenses16.22M30.51M30.22M21.56M
InterestPayable0.002.94M0.00
Payables23.59M16.04M16.62M15.35M
AccountsPayable23.59M16.04M16.62M15.35M
TotalAssets269.75M326.74M318.24M320.16M
TotalNonCurrentAssets146.23M167.12M163.90M136.92M
OtherNonCurrentAssets3.01M3.00M1.40M1.40M
InvestmentsAndAdvances6.75M6.77M6.33M6.66M
LongTermEquityInvestment6.75M6.77M6.33M6.66M
GoodwillAndOtherIntangibleAssets821.00K1.12M2.08M2.57M
OtherIntangibleAssets821.00K1.12M2.08M2.57M
NetPPE135.65M156.24M154.09M126.29M
AccumulatedDepreciation-42.30M-33.33M-20.39M-14.48M
GrossPPE177.96M189.56M174.49M140.77M
Leases99.37M103.08M91.05M60.88M
OtherProperties70.53M78.38M76.00M73.45M
MachineryFurnitureEquipment8.05M8.10M7.43M6.44M
Properties0.000.000.000.00
CurrentAssets123.52M159.62M154.34M183.24M
OtherCurrentAssets2.02M1.02M1.67M2.42M
PrepaidAssets6.83M5.62M8.13M8.10M
Inventory385.00K0.00
Receivables10.63M23.41M29.02M35.02M
OtherReceivables950.00K
TaxesReceivable8.97M13.28M7.69M12.63M
AccountsReceivable707.00K10.14M21.33M22.38M
CashCashEquivalentsAndShortTermInvestments103.66M129.57M115.52M137.70M
CashAndCashEquivalents103.66M129.57M115.52M137.70M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-109.45M-125.54M-118.06M-65.75M
RepaymentOfDebt0.00-1.00K
IssuanceOfDebt0.0075.00M0.00
IssuanceOfCapitalStock59.39M91.95M25.00M0.00
CapitalExpenditure-4.96M-20.17M-44.96M-55.22M
InterestPaidSupplementalData12.03M13.05M329.00K139.00K
EndCashPosition105.67M130.65M115.52M137.70M
BeginningCashPosition130.65M115.52M137.70M209.52M
EffectOfExchangeRateChanges1.50M2.44M674.00K-1.28M
ChangesInCash-26.48M12.69M-22.86M-70.54M
FinancingCashFlow54.53M84.02M95.20M1.71M
CashFlowFromContinuingFinancingActivities54.53M84.02M95.20M1.71M
NetOtherFinancingCharges-4.86M-7.94M-5.03M
InterestPaidCFF-2.26M0.00
ProceedsFromStockOptionExercised0.0010.00K231.00K1.71M
CashDividendsPaid0.000.00
NetCommonStockIssuance59.39M91.95M25.00M0.00
CommonStockIssuance59.39M91.95M25.00M0.00
NetIssuancePaymentsOfDebt0.0075.00M-1.00K
NetShortTermDebtIssuance0.0075.00M
ShortTermDebtIssuance0.0075.00M
NetLongTermDebtIssuance75.00M-1.00K
LongTermDebtPayments0.00-1.00K
LongTermDebtIssuance75.00M0.00
InvestingCashFlow23.48M34.03M-44.96M-61.72M
CashFlowFromContinuingInvestingActivities23.48M34.03M-44.96M-61.72M
NetOtherInvestingChanges28.43M54.21M
NetBusinessPurchaseAndSale0.00-6.50M
PurchaseOfBusiness0.00-6.50M
NetIntangiblesPurchaseAndSale54.21M0.000.00
SaleOfIntangibles54.21M0.00
PurchaseOfIntangibles0.00
NetPPEPurchaseAndSale-4.96M-20.17M-44.96M-55.22M
PurchaseOfPPE-4.96M-20.17M-44.96M-55.22M
OperatingCashFlow-104.50M-105.36M-73.10M-10.53M
CashFlowFromContinuingOperatingActivities-104.64M-105.37M-73.22M-10.53M
ChangeInWorkingCapital29.64M-983.00K9.62M31.28M
ChangeInOtherWorkingCapital26.66M-7.51M-15.92M-7.49M
ChangeInOtherCurrentLiabilities32.00K-1.35M4.01M-23.00K
ChangeInOtherCurrentAssets-1.54M-1.59M346.00K1.70M
ChangeInPayablesAndAccruedExpense-3.22M1.95M16.35M21.46M
ChangeInAccruedExpense-13.96M-382.00K12.61M8.12M
ChangeInPayable10.74M2.33M3.74M13.35M
ChangeInAccountPayable10.74M2.33M3.74M13.35M
ChangeInPrepaidAssets-1.33M2.69M-329.00K-1.08M
ChangeInInventory-387.00K0.00
ChangeInReceivables9.43M4.83M5.17M16.70M
ChangesInAccountReceivables6.33M9.97M1.03M16.39M
OtherNonCashItems1.30M545.00K218.00K2.74M
StockBasedCompensation25.19M27.72M28.62M20.78M
AssetImpairmentCharge0.001.15M0.00
DepreciationAmortizationDepletion12.68M13.72M8.60M7.87M
DepreciationAndAmortization12.68M13.72M8.60M7.87M
AmortizationCashFlow300.00K300.00K200.00K
AmortizationOfIntangibles300.00K300.00K200.00K
Depreciation12.38M13.42M8.40M
OperatingGainsLosses-25.52M-63.49M9.45M6.36M
EarningsLossesFromEquityInvestments17.00K6.00K0.009.00K
NetForeignCurrencyExchangeGainLoss2.89M-9.30M9.45M6.29M
GainLossOnSaleOfPPE-28.43M-54.20M0.0056.00K
NetIncomeFromContinuingOperations-147.79M-84.03M-129.62M-79.56M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for MGTX
Date User Asset Broker Type Position Size Entry Price Patterns