Symbols / OBIO Stock $4.20 -0.24% Orchestra BioMed Holdings, Inc.

Healthcare • Biotechnology • United States • NGM
OBIO (Stock) Chart
O: — H: — L: — C: — V: —
SMA 20: — SMA 50: — SMA 200: —
About

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a bioelectronic product candidate that aims to reduce chronic sympathetic nervous system activity in heart failure. In addition, the company offers FreeHold devices and additional minimally invasive surgery enabling devices; and Pure-Vu system, a medical device to facilitate the cleansing of a poorly prepared gastrointestinal tract during colonoscopy and upper gastrointestinal endoscopy procedures. It has a collaboration agreement with Medtronic, Inc. for the development of AVIM therapy for the treatment of HTN in pacemaker-indicated patients; and a strategic collaboration with Terumo Corporation and Terumo Medical Corporation for the development and commercialization of Virtue SAB for the treatment of coronary and peripheral vascular disease. Orchestra BioMed Holdings, Inc. was founded in 2018 and is headquartered in New Hope, Pennsylvania.

Stock Fundamentals
Scroll to Statements
Market Cap 245.79M Enterprise Value 165.62M Income -52.95M Sales 33.48M Book/sh 0.94 Cash/sh 1.82
Dividend Yield — Payout 0.00% Employees 86 IPO — P/E — Forward P/E -2.47
PEG — P/S 7.34 P/B 4.47 P/C — EV/EBITDA -3.22 EV/Sales 4.95
Quick Ratio 6.37 Current Ratio 6.45 Debt/Eq 25.17 LT Debt/Eq — EPS (ttm) -1.11 EPS next Y -1.70
EPS Growth — Revenue Growth 121.20% Earnings 2026-05-08 ROA -33.90% ROE -109.41% ROIC —
Gross Margin 99.43% Oper. Margin 21.85% Profit Margin -157.40% Shs Outstand 58.52M Shs Float 32.49M Short Float 2.46%
Short Ratio 3.91 Short Interest — 52W High 5.42 52W Low 2.20 Beta 0.60 Avg Volume 201.13K
Volume 10.83K Target Price $12.43 Recom Strong_buy Prev Close $4.21 Price $4.20 Change -0.24%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$12.43
Mean price target
2. Current target
$4.20
Latest analyst target
3. DCF / Fair value
$-6.23
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$4.20
Low
$9.00
High
$20.00
Mean
$12.43

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-12 main Chardan Capital Buy → Buy $20
2026-01-09 main Barclays Overweight → Overweight $12
2025-12-10 init TD Cowen — → Buy $15
2025-11-13 main Chardan Capital Buy → Buy $20
2025-11-12 main Barclays Overweight → Overweight $11
2025-09-04 main HC Wainwright & Co. Buy → Buy $10
2025-08-20 down BTIG Buy → Neutral —
2025-08-13 main Chardan Capital Buy → Buy $20
2025-08-07 main Chardan Capital Buy → Buy $20
2025-05-13 main Chardan Capital Buy → Buy $20
2025-05-05 main Barclays Overweight → Overweight $12
2025-04-22 main Chardan Capital Buy → Buy $20
2025-04-04 main HC Wainwright & Co. Buy → Buy $12
2025-04-01 main Chardan Capital Buy → Buy $20
2025-03-20 init BTIG — → Buy $12
2025-03-10 reit HC Wainwright & Co. Buy → Buy $14
2025-01-02 init Barclays — → Overweight $16
2024-11-15 reit HC Wainwright & Co. Buy → Buy $14
2024-11-13 main Chardan Capital Buy → Buy $20
2024-08-22 init HC Wainwright & Co. — → Buy $14
News
RSS: Latest OBIO news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-03-13 HOCHMAN DAVID P Chief Executive Officer — 10,000 $4.29 $42,900
2026-02-12 SHERMAN DARREN President — 397,000 $0.00 $0
2026-02-12 TAYLOR ANDREW LAWRENCE Chief Financial Officer — 181,000 $0.00 $0
2026-02-12 HOCHMAN DAVID P Chief Executive Officer — 504,000 $0.00 $0
2025-11-14 HOCHMAN DAVID P Chief Executive Officer — 5,000 $4.07 $20,350
2025-09-19 ARYEH JASON M Director — 1,000 $2.45 $2,450
2025-08-25 FAIN ERIC S Director — 5,760 $2.61 $15,034
2025-08-25 SHERMAN DARREN President — 3,000 $2.62 $7,860
2025-08-25 TAYLOR ANDREW LAWRENCE Chief Financial Officer — 2,000 $2.55 $5,100
2025-08-21 HOCHMAN DAVID P Chief Executive Officer — 6,000 $2.49 $14,940
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
33.48
+1169.22%
2.64
-4.42%
2.76
-21.88%
3.53
Operating Revenue
33.48
+1169.22%
2.64
-4.42%
2.76
-21.88%
3.53
Cost Of Revenue
0.19
-6.86%
0.20
+9.68%
0.19
-11.85%
0.21
Reconciled Cost Of Revenue
0.19
-6.86%
0.20
+9.68%
0.19
-11.85%
0.21
Gross Profit
33.29
+1267.79%
2.43
-5.44%
2.57
-22.52%
3.32
Operating Expense
85.10
+27.52%
66.73
+23.40%
54.08
+50.31%
35.98
Research And Development
58.19
+35.93%
42.80
+26.56%
33.82
+54.12%
21.95
Selling General And Administration
26.91
+12.47%
23.93
+18.13%
20.26
+44.35%
14.03
Total Expenses
85.29
+27.41%
66.94
+23.35%
54.27
+49.95%
36.19
Operating Income
-51.81
+19.43%
-64.30
-24.84%
-51.51
-57.72%
-32.66
Total Operating Income As Reported
-51.81
+19.43%
-64.30
-24.84%
-51.51
-57.72%
-32.66
EBITDA
-51.23
+19.95%
-63.99
-24.94%
-51.22
-57.91%
-32.44
Normalized EBITDA
-51.48
+19.47%
-63.92
-28.48%
-49.76
-58.29%
-31.43
Reconciled Depreciation
0.33
+6.17%
0.31
+7.32%
0.29
+29.28%
0.22
EBIT
-51.55
+19.83%
-64.30
-24.84%
-51.51
-57.72%
-32.66
Total Unusual Items
0.25
+473.53%
-0.07
+95.35%
-1.46
-46.15%
-1.00
Total Unusual Items Excluding Goodwill
0.25
+473.53%
-0.07
+95.35%
-1.46
-46.15%
-1.00
Special Income Charges
—
0.00
+100.00%
-1.15
-68.77%
-0.68
Other Special Charges
—
—
1.15
+68.77%
0.68
Net Income
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Pretax Income
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Net Non Operating Interest Income Expense
-1.15
-134.21%
3.36
-12.81%
3.85
+7598.00%
0.05
Interest Expense Non Operating
1.15
—
—
—
Net Interest Income
-1.15
-134.21%
3.36
-12.81%
3.85
+7598.00%
0.05
Interest Expense
1.15
—
—
—
Interest Income Non Operating
—
3.36
-12.81%
3.85
+7598.00%
0.05
Interest Income
—
3.36
-12.81%
3.85
+7598.00%
0.05
Other Income Expense
0.25
+421.52%
-0.08
+94.60%
-1.46
-46.15%
-1.00
Other Non Operating Income Expenses
—
-0.01
—
—
Gain On Sale Of Security
0.25
+473.53%
-0.07
+78.21%
-0.31
+2.19%
-0.32
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Net Income From Continuing Operation Net Minority Interest
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Net Income From Continuing And Discontinued Operation
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Net Income Continuous Operations
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Normalized Income
-52.95
+13.13%
-60.96
-27.91%
-47.66
-46.16%
-32.61
Net Income Common Stockholders
-52.95
+13.22%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Diluted EPS
—
-1.66
-12.16%
-1.48
-39.22%
-1.06
Basic EPS
—
-1.66
-12.16%
-1.48
-39.22%
-1.06
Basic Average Shares
—
36.82
+10.82%
33.23
+5.10%
31.61
Diluted Average Shares
—
36.82
+10.82%
33.23
+5.10%
31.61
Diluted NI Availto Com Stockholders
-52.95
+13.22%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Preferred Stock Dividends
0.25
—
—
—
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
114.86
+50.78%
76.17
-20.00%
95.21
-0.38%
95.57
Current Assets
107.91
+56.01%
69.17
-22.38%
89.11
+5.22%
84.69
Cash Cash Equivalents And Short Term Investments
106.51
+59.42%
66.81
-23.73%
87.59
+4.55%
83.78
Cash And Cash Equivalents
34.69
+55.83%
22.26
-27.15%
30.56
+54.46%
19.78
Other Short Term Investments
71.82
+61.21%
44.55
-21.89%
57.04
-10.88%
64.00
Receivables
0.10
+3.26%
0.09
-7.07%
0.10
+3.13%
0.10
Accounts Receivable
0.10
+3.26%
0.09
-7.07%
0.10
+3.13%
0.10
Inventory
0.31
+79.19%
0.17
+18.49%
0.15
-47.10%
0.28
Prepaid Assets
—
—
—
—
Other Current Assets
0.99
-52.53%
2.09
+64.36%
1.27
+139.02%
0.53
Total Non Current Assets
6.95
-0.80%
7.00
+14.82%
6.10
-43.96%
10.88
Net PPE
3.21
-7.92%
3.49
+23.04%
2.83
-22.91%
3.68
Gross PPE
4.84
+1.09%
4.79
+23.52%
3.88
-12.93%
4.45
Accumulated Depreciation
-1.63
-25.17%
-1.30
-24.81%
-1.04
-34.19%
-0.78
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
0.44
+0.00%
0.44
+29.45%
0.34
-5.77%
0.36
Construction In Progress
—
—
—
—
Other Properties
4.24
+1.24%
4.19
+25.66%
3.33
-14.54%
3.90
Leases
0.16
+0.00%
0.16
-21.67%
0.20
+6.28%
0.19
Investments And Advances
2.50
+0.00%
2.50
+0.00%
2.50
+0.00%
2.50
Non Current Prepaid Assets
—
—
—
—
Other Non Current Assets
1.24
+21.57%
1.02
+32.64%
0.77
-83.68%
4.71
Total Liabilities Net Minority Interest
61.29
+41.82%
43.22
+59.06%
27.17
-36.87%
43.04
Current Liabilities
16.74
+3.26%
16.21
+44.60%
11.21
-39.63%
18.57
Payables And Accrued Expenses
11.82
+37.40%
8.61
+59.73%
5.39
-21.50%
6.86
Payables
6.09
+18.72%
5.13
+77.03%
2.90
-26.92%
3.97
Accounts Payable
6.09
+18.72%
5.13
+77.03%
2.90
-26.92%
3.97
Current Accrued Expenses
5.73
+65.03%
3.47
+39.55%
2.49
-14.09%
2.90
Pensionand Other Post Retirement Benefit Plans Current
4.16
+59.26%
2.61
-1.84%
2.66
+7.30%
2.48
Total Tax Payable
—
—
—
—
Current Debt And Capital Lease Obligation
0.75
+36.55%
0.55
-15.25%
0.65
-6.89%
0.70
Current Debt
—
—
—
—
Other Current Borrowings
—
—
—
—
Current Capital Lease Obligation
0.75
+36.55%
0.55
-15.25%
0.65
-6.89%
0.70
Current Deferred Liabilities
0.00
-100.00%
4.44
+76.85%
2.51
-61.00%
6.44
Current Deferred Revenue
0.00
-100.00%
4.44
+76.85%
2.51
-61.00%
6.44
Other Current Liabilities
—
—
—
2.09
Total Non Current Liabilities Net Minority Interest
44.55
+64.95%
27.01
+69.21%
15.96
-34.78%
24.47
Long Term Debt And Capital Lease Obligation
15.20
-4.85%
15.98
+1439.40%
1.04
-90.71%
11.17
Long Term Debt
14.27
-0.17%
14.29
—
9.49
Long Term Capital Lease Obligation
0.94
-44.52%
1.69
+62.52%
1.04
-38.32%
1.68
Non Current Deferred Liabilities
0.00
-100.00%
10.99
-26.36%
14.92
+13.89%
13.10
Non Current Deferred Revenue
0.00
-100.00%
10.99
-26.36%
14.92
+13.89%
13.10
Other Non Current Liabilities
16.79
+41875.00%
0.04
—
0.20
Preferred Securities Outside Stock Equity
9.81
0.00
—
—
Stockholders Equity
53.57
+62.54%
32.96
-51.56%
68.04
+29.52%
52.53
Common Stock Equity
53.57
+62.54%
32.96
-51.56%
68.04
+29.52%
52.53
Capital Stock
0.01
+50.00%
0.00
+0.00%
0.00
+100.00%
0.00
Common Stock
0.01
+50.00%
0.00
+0.00%
0.00
+100.00%
0.00
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
57.03
+49.32%
38.19
+6.76%
35.78
+13.17%
31.61
Ordinary Shares Number
57.03
+49.32%
38.19
+6.76%
35.78
+13.17%
31.61
Additional Paid In Capital
416.08
+21.38%
342.78
+8.17%
316.90
+25.62%
252.27
Retained Earnings
-362.58
-17.01%
-309.88
-24.52%
-248.85
-24.59%
-199.73
Gains Losses Not Affecting Retained Earnings
0.06
+15.38%
0.05
+620.00%
-0.01
-25.00%
-0.01
Other Equity Adjustments
0.06
+15.38%
0.05
+620.00%
-0.01
-25.00%
-0.01
Total Equity Gross Minority Interest
53.57
+62.54%
32.96
-51.56%
68.04
+29.52%
52.53
Total Capitalization
67.84
+43.57%
47.25
-30.56%
68.04
+9.70%
62.02
Working Capital
91.17
+72.15%
52.96
-32.02%
77.91
+17.82%
66.12
Invested Capital
67.84
+43.57%
47.25
-30.56%
68.04
+9.70%
62.02
Total Debt
15.96
-3.47%
16.53
+879.79%
1.69
-85.79%
11.87
Capital Lease Obligations
1.69
-24.59%
2.24
+32.60%
1.69
-29.12%
2.38
Net Tangible Assets
53.57
+62.54%
32.96
-51.56%
68.04
+29.52%
52.53
Tangible Book Value
53.57
+62.54%
32.96
-51.56%
68.04
+29.52%
52.53
Derivative Product Liabilities
2.75
0.00
—
—
Investmentin Financial Assets
2.50
+0.00%
2.50
+0.00%
2.50
+0.00%
2.50
Trading Securities
2.50
+0.00%
2.50
+0.00%
2.50
+0.00%
2.50
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-48.96
+3.15%
-50.56
-9.61%
-46.13
-57.49%
-29.29
Cash Flow From Continuing Operating Activities
-48.96
+3.15%
-50.56
-9.61%
-46.13
-57.49%
-29.29
Net Income From Continuing Operations
-52.70
+13.64%
-61.02
-24.23%
-49.12
-46.16%
-33.61
Depreciation Amortization Depletion
0.33
+6.17%
0.31
+7.32%
0.29
+29.28%
0.22
Depreciation And Amortization
0.33
+6.17%
0.31
+7.32%
0.29
+29.28%
0.22
Other Non Cash Items
2.06
+757.92%
0.24
+107.80%
-3.08
-2394.78%
0.13
Stock Based Compensation
11.98
+12.84%
10.62
+39.21%
7.62
+123.41%
3.41
Operating Gains Losses
-0.25
—
1.45
-28.89%
2.03
Gain Loss On Investment Securities
-0.25
—
0.29
-78.22%
1.35
Unrealized Gain Loss On Investment Securities
0.00
-100.00%
0.07
+277.78%
0.02
+101.75%
-1.03
Change In Working Capital
-10.37
-1255.82%
-0.77
+76.87%
-3.31
-633.26%
-0.45
Change In Receivables
-0.00
-113.64%
0.02
+833.33%
-0.00
-112.00%
0.03
Changes In Account Receivables
-0.00
-113.64%
0.02
+833.33%
-0.00
-112.00%
0.03
Change In Inventory
-0.14
-389.29%
-0.03
-121.37%
0.13
+162.98%
-0.21
Change In Prepaid Assets
0.88
+182.17%
-1.07
-37.13%
-0.78
-77.90%
-0.44
Change In Payables And Accrued Expense
4.87
+63.89%
2.97
+1947.59%
0.14
-95.67%
3.35
Change In Payable
—
—
—
—
Change In Account Payable
—
—
—
—
Change In Other Working Capital
-15.43
-669.48%
-2.00
+4.80%
-2.11
+26.42%
-2.86
Change In Other Current Liabilities
-0.55
+15.64%
-0.65
+5.92%
-0.69
-117.24%
-0.32
Investing Cash Flow
-26.94
-305.83%
13.09
+22.48%
10.69
+116.67%
-64.12
Cash Flow From Continuing Investing Activities
-26.94
-305.83%
13.09
+22.48%
10.69
+116.67%
-64.12
Net PPE Purchase And Sale
-0.49
-69.20%
-0.29
-270.51%
-0.08
+86.80%
-0.59
Purchase Of PPE
-0.49
-69.20%
-0.29
-270.51%
-0.08
+86.80%
-0.59
Capital Expenditure
-0.49
-69.20%
-0.29
-270.51%
-0.08
+86.80%
-0.59
Net Investment Purchase And Sale
-26.45
-289.21%
13.98
+29.87%
10.77
+116.94%
-63.53
Purchase Of Investment
-76.31
-5.04%
-72.65
+48.85%
-142.03
-123.56%
-63.53
Sale Of Investment
49.86
-42.44%
86.63
-43.31%
152.80
0.00
Net Other Investing Changes
—
-0.60
—
—
Financing Cash Flow
88.33
+202.81%
29.17
-36.88%
46.22
-55.24%
103.26
Cash Flow From Continuing Financing Activities
88.33
+202.81%
29.17
-36.88%
46.22
-55.24%
103.26
Net Issuance Payments Of Debt
0.00
-100.00%
15.00
+238.26%
-10.85
-405.26%
3.55
Issuance Of Debt
0.00
-100.00%
15.00
0.00
-100.00%
10.00
Repayment Of Debt
—
0.00
+100.00%
-10.85
-68.31%
-6.45
Long Term Debt Issuance
0.00
-100.00%
15.00
0.00
-100.00%
10.00
Long Term Debt Payments
—
0.00
+100.00%
-10.85
-68.31%
-6.45
Net Long Term Debt Issuance
0.00
-100.00%
15.00
+238.26%
-10.85
-405.26%
3.55
Net Common Stock Issuance
59.32
+294.57%
15.04
0.00
-100.00%
109.83
Proceeds From Stock Option Exercised
0.09
-62.08%
0.24
-5.51%
0.25
+33.68%
0.19
Net Other Financing Charges
16.36
+1582.07%
-1.10
-101.94%
56.81
+650.64%
-10.32
Changes In Cash
12.43
+249.78%
-8.30
-177.01%
10.78
+9.44%
9.85
Beginning Cash Position
22.26
-27.15%
30.56
+54.46%
19.78
+99.07%
9.94
End Cash Position
34.69
+55.83%
22.26
-27.15%
30.56
+54.46%
19.78
Free Cash Flow
-49.45
+2.74%
-50.85
-10.05%
-46.20
-54.64%
-29.88
Interest Paid Supplemental Data
1.45
+1318.63%
0.10
-90.88%
1.12
-18.38%
1.37
Common Stock Issuance
59.32
+294.57%
15.04
0.00
-100.00%
109.83
Issuance Of Capital Stock
71.88
+378.08%
15.04
0.00
-100.00%
109.83
Net Preferred Stock Issuance
12.56
0.00
—
—
Preferred Stock Issuance
12.56
0.00
—
—
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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