Symbols / PBYI Stock $7.17 +1.27% Puma Biotechnology, Inc.
PBYI (Stock) Chart
Stock Fundamentals
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About
Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. It sells its products through specialty pharmacy and distributor networks. The company has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Puma Biotechnology, Inc. was founded in 2010 and is headquartered in Los Angeles, California.
Ratings
Latest analyst rating changes
| Date | Action | Analyst | Rating Change | Price Target |
|---|---|---|---|---|
| 2025-02-28 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-12-23 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-11-20 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-11-08 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-08-02 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-07-26 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-06-04 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-06-03 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-05-20 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-05-03 | reit | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-03-01 | main | HC Wainwright & Co. | Buy → Buy | $7 |
| 2024-02-13 | reit | HC Wainwright & Co. | Buy → Buy | $8 |
| 2023-09-20 | reit | HC Wainwright & Co. | Buy → Buy | $8 |
| 2023-08-04 | reit | HC Wainwright & Co. | Buy → Buy | $8 |
| 2023-06-05 | reit | HC Wainwright & Co. | Buy → Buy | $8 |
| 2023-05-05 | reit | HC Wainwright & Co. | — → Buy | $8 |
| 2023-03-06 | reit | HC Wainwright & Co. | — → Buy | $8 |
| 2022-08-05 | main | HC Wainwright & Co. | — → Buy | $8 |
| 2022-05-06 | main | HC Wainwright & Co. | — → Buy | $12 |
| 2021-09-28 | up | Citigroup | Neutral → Buy | — |
- Puma Biotechnology, Inc. (NASDAQ:PBYI) Analysts Are Pretty Bullish On The Stock After Recent Results - simplywall.st Mon, 11 May 2026 13
- PBYI Q1 earnings & sales beat estimates, 2026 guidance raised - MSN ue, 12 May 2026 00
- Cancer drug NERLYNX demand pushes Puma to raise 2026 outlook - Stock Titan hu, 07 May 2026 20
- $PBYI stock is down 12% today. Here's what we see in our data. - Quiver Quantitative Fri, 27 Feb 2026 08
- Earnings Update: Here's Why Analysts Just Lifted Their Puma Biotechnology, Inc. (NASDAQ:PBYI) Price Target To US$5.00 - Yahoo Finance Mon, 11 May 2026 13
- Puma Biotechnology (PBYI) Net Margin Steady At 13.6% Challenges Bearish Earnings Narratives - Sahm Sat, 09 May 2026 07
- Six new Puma hires get stock awards covering 59,750 shares - Stock Titan Wed, 06 May 2026 21
- Puma Biotech (PBYI) Reports Q1 Loss, Tops Revenue Estimates - Yahoo Finance hu, 07 May 2026 23
- CRMD vs. PBYI: Which Small-Cap Biotech Stock Is the Better Buy? - Yahoo Finance Wed, 17 Dec 2025 08
- Is Puma Biotechnology, Inc.'s (NASDAQ:PBYI) Stock's Recent Performance Being Led By Its Attractive Financial Prospects? - simplywall.st Fri, 07 Nov 2025 08
- [ARS] PUMA BIOTECHNOLOGY, INC. SEC Filing - Stock Titan ue, 28 Apr 2026 07
- With 60% ownership of the shares, Puma Biotechnology, Inc. (NASDAQ:PBYI) is heavily dominated by institutional owners - Yahoo Finance Sun, 30 Nov 2025 08
- Puma Biotechnology stock declines more than 9% in a month: Here's why - MSN Sat, 25 Apr 2026 12
- What Do Analysts Think About Puma Biotechnology (PBYI)? - Yahoo Finance Wed, 17 Sep 2025 07
- IRWD vs. PBYI: Which Small-Cap Biotech Stock Is a Better Buy? - Zacks Investment Research hu, 12 Mar 2026 07
Insider Transactions
Financials
| Line Item | Trend | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|---|
| Total Revenue |
|
228.37
-0.91%
|
230.47
-2.19%
|
235.64
+3.34%
|
228.03
|
| Operating Revenue |
|
228.37
-0.91%
|
230.47
-2.19%
|
235.64
+3.34%
|
228.03
|
| Cost Of Revenue |
|
58.16
-9.70%
|
64.40
+2.75%
|
62.68
+13.77%
|
55.09
|
| Reconciled Cost Of Revenue |
|
58.16
-9.70%
|
64.40
+2.75%
|
62.68
+13.77%
|
55.09
|
| Gross Profit |
|
170.21
+2.50%
|
166.06
-3.98%
|
172.96
+0.01%
|
172.94
|
| Operating Expense |
|
132.91
-1.62%
|
135.10
-3.72%
|
140.31
-1.34%
|
142.22
|
| Research And Development |
|
62.07
+12.98%
|
54.94
+9.04%
|
50.38
-3.56%
|
52.24
|
| Selling General And Administration |
|
71.21
-11.74%
|
80.68
-10.29%
|
89.93
-0.05%
|
89.98
|
| General And Administrative Expense |
|
71.21
-11.74%
|
80.68
-8.76%
|
88.43
-1.72%
|
89.98
|
| Salaries And Wages |
|
38.95
+4.91%
|
37.12
-7.99%
|
40.34
+6.23%
|
37.98
|
| Other Gand A |
|
32.26
-25.93%
|
43.56
-9.40%
|
48.08
-7.53%
|
52.00
|
| Total Expenses |
|
191.07
-4.23%
|
199.50
-1.72%
|
203.00
+2.88%
|
197.31
|
| Operating Income |
|
37.30
+20.45%
|
30.97
-5.13%
|
32.64
+6.25%
|
30.72
|
| Total Operating Income As Reported |
|
37.30
+20.45%
|
30.97
-5.13%
|
32.64
+37.61%
|
23.72
|
| EBITDA |
|
53.34
+10.95%
|
48.08
+1.16%
|
47.52
+117.11%
|
21.89
|
| Normalized EBITDA |
|
53.34
+10.95%
|
48.08
+1.16%
|
47.52
+14.94%
|
41.34
|
| Reconciled Depreciation |
|
10.94
-5.09%
|
11.52
+0.04%
|
11.52
+17.06%
|
9.84
|
| EBIT |
|
42.40
+16.01%
|
36.55
+1.52%
|
36.00
+198.81%
|
12.05
|
| Total Unusual Items |
|
—
|
0.00
+100.00%
|
-0.62
+96.79%
|
-19.46
|
| Total Unusual Items Excluding Goodwill |
|
—
|
0.00
+100.00%
|
-0.62
+96.79%
|
-19.46
|
| Special Income Charges |
|
—
|
0.00
+100.00%
|
-0.62
+96.79%
|
-19.46
|
| Other Special Charges |
|
—
|
—
|
—
|
19.46
|
| Restructuring And Mergern Acquisition |
|
—
|
—
|
0.00
-100.00%
|
7.00
|
| Write Off |
|
—
|
0.00
-100.00%
|
0.62
|
0.00
|
| Net Income |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Pretax Income |
|
35.78
+48.47%
|
24.10
+6.29%
|
22.67
+4861.49%
|
0.46
|
| Net Non Operating Interest Income Expense |
|
-2.54
+67.08%
|
-7.73
+27.94%
|
-10.72
+0.50%
|
-10.78
|
| Interest Expense Non Operating |
|
6.62
-46.82%
|
12.45
-6.59%
|
13.33
+14.99%
|
11.59
|
| Net Interest Income |
|
-2.54
+67.08%
|
-7.73
+27.94%
|
-10.72
+0.50%
|
-10.78
|
| Interest Expense |
|
6.62
-46.82%
|
12.45
-6.59%
|
13.33
+14.99%
|
11.59
|
| Interest Income Non Operating |
|
4.08
-13.67%
|
4.72
+81.34%
|
2.60
+220.42%
|
0.81
|
| Interest Income |
|
4.08
-13.67%
|
4.72
+81.34%
|
2.60
+220.42%
|
0.81
|
| Other Income Expense |
|
1.03
+19.14%
|
0.86
+13.57%
|
0.76
+103.90%
|
-19.48
|
| Other Non Operating Income Expenses |
|
1.03
+19.14%
|
0.86
+13.57%
|
0.76
+2810.71%
|
-0.03
|
| Tax Provision |
|
4.67
+175.61%
|
-6.18
-670.45%
|
1.08
+138.02%
|
0.46
|
| Tax Rate For Calcs |
|
0.00
-37.62%
|
0.00
+339.66%
|
0.00
-77.26%
|
0.00
|
| Tax Effect Of Unusual Items |
|
0.00
|
0.00
|
0.00
+100.00%
|
-4.09
|
| Net Income Including Noncontrolling Interests |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Net Income From Continuing Operation Net Minority Interest |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Net Income From Continuing And Discontinued Operation |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Net Income Continuous Operations |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Normalized Income |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+40.45%
|
15.37
|
| Net Income Common Stockholders |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Diluted EPS |
|
0.61
-1.61%
|
0.62
+37.78%
|
0.45
|
0.00
|
| Basic EPS |
|
0.62
+0.00%
|
0.62
+34.78%
|
0.46
|
0.00
|
| Basic Average Shares |
|
50.01
+2.80%
|
48.65
+3.21%
|
47.13
+5.51%
|
44.67
|
| Diluted Average Shares |
|
50.65
+3.16%
|
49.10
+3.26%
|
47.55
+5.83%
|
44.93
|
| Diluted NI Availto Com Stockholders |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Provision For Doubtful Accounts |
|
-0.36
+30.25%
|
-0.52
-158.91%
|
0.88
|
0.00
|
| Line Item | Trend | 2023-12-31 |
|---|---|---|
| Total Assets |
|
230.53
|
| Current Assets |
|
156.19
|
| Cash Cash Equivalents And Short Term Investments |
|
95.94
|
| Cash And Cash Equivalents |
|
84.58
|
| Other Short Term Investments |
|
11.35
|
| Receivables |
|
47.84
|
| Accounts Receivable |
|
47.84
|
| Gross Accounts Receivable |
|
48.72
|
| Allowance For Doubtful Accounts Receivable |
|
-0.88
|
| Other Receivables |
|
0.65
|
| Inventory |
|
7.08
|
| Raw Materials |
|
5.69
|
| Work In Process |
|
0.82
|
| Finished Goods |
|
0.57
|
| Prepaid Assets |
|
3.02
|
| Restricted Cash |
|
—
|
| Other Current Assets |
|
2.31
|
| Total Non Current Assets |
|
74.34
|
| Net PPE |
|
8.65
|
| Gross PPE |
|
16.33
|
| Accumulated Depreciation |
|
-7.68
|
| Properties |
|
0.00
|
| Buildings And Improvements |
|
7.79
|
| Machinery Furniture Equipment |
|
4.76
|
| Other Properties |
|
0.30
|
| Leases |
|
3.78
|
| Goodwill And Other Intangible Assets |
|
60.87
|
| Other Intangible Assets |
|
60.87
|
| Non Current Deferred Assets |
|
0.00
|
| Non Current Deferred Taxes Assets |
|
0.00
|
| Non Current Prepaid Assets |
|
0.21
|
| Other Non Current Assets |
|
4.62
|
| Total Liabilities Net Minority Interest |
|
177.09
|
| Current Liabilities |
|
99.38
|
| Payables And Accrued Expenses |
|
49.33
|
| Payables |
|
6.89
|
| Accounts Payable |
|
6.89
|
| Current Accrued Expenses |
|
42.44
|
| Pensionand Other Post Retirement Benefit Plans Current |
|
10.28
|
| Current Debt And Capital Lease Obligation |
|
38.80
|
| Current Debt |
|
34.00
|
| Other Current Borrowings |
|
34.00
|
| Current Capital Lease Obligation |
|
4.80
|
| Other Current Liabilities |
|
0.97
|
| Total Non Current Liabilities Net Minority Interest |
|
77.70
|
| Long Term Debt And Capital Lease Obligation |
|
72.69
|
| Long Term Debt |
|
65.66
|
| Long Term Capital Lease Obligation |
|
7.03
|
| Other Non Current Liabilities |
|
4.89
|
| Stockholders Equity |
|
53.44
|
| Common Stock Equity |
|
53.44
|
| Capital Stock |
|
0.01
|
| Common Stock |
|
0.01
|
| Share Issued |
|
47.65
|
| Ordinary Shares Number |
|
47.65
|
| Treasury Shares Number |
|
0.00
|
| Additional Paid In Capital |
|
1,398.61
|
| Retained Earnings |
|
-1,345.16
|
| Gains Losses Not Affecting Retained Earnings |
|
-0.00
|
| Other Equity Adjustments |
|
-0.00
|
| Total Equity Gross Minority Interest |
|
53.44
|
| Total Capitalization |
|
119.10
|
| Working Capital |
|
56.80
|
| Invested Capital |
|
153.10
|
| Total Debt |
|
111.49
|
| Net Debt |
|
15.07
|
| Capital Lease Obligations |
|
11.83
|
| Net Tangible Assets |
|
-7.43
|
| Tangible Book Value |
|
-7.43
|
| Non Current Accrued Expenses |
|
0.12
|
| Line Item | Trend | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|---|
| Operating Cash Flow |
|
41.80
+7.41%
|
38.92
+44.09%
|
27.01
+270.65%
|
-15.83
|
| Cash Flow From Continuing Operating Activities |
|
41.80
+7.41%
|
38.92
+44.09%
|
27.01
+270.65%
|
-15.83
|
| Net Income From Continuing Operations |
|
31.11
+2.75%
|
30.28
+40.23%
|
21.59
+1079450.00%
|
0.00
|
| Depreciation Amortization Depletion |
|
10.94
-5.09%
|
11.52
+0.04%
|
11.52
+17.06%
|
9.84
|
| Depreciation And Amortization |
|
10.94
-5.09%
|
11.52
+0.04%
|
11.52
+17.06%
|
9.84
|
| Other Non Cash Items |
|
—
|
—
|
—
|
7.00
|
| Stock Based Compensation |
|
6.94
-15.78%
|
8.24
-19.54%
|
10.25
-13.35%
|
11.83
|
| Provisionand Write Offof Assets |
|
-0.36
+30.25%
|
-0.52
-158.91%
|
0.88
|
0.00
|
| Asset Impairment Charge |
|
0.00
|
0.00
-100.00%
|
0.62
|
0.00
|
| Deferred Tax |
|
3.25
+145.87%
|
-7.08
|
0.00
|
—
|
| Deferred Income Tax |
|
3.25
+145.87%
|
-7.08
|
0.00
|
—
|
| Operating Gains Losses |
|
0.00
|
—
|
—
|
0.00
|
| Gain Loss On Sale Of PPE |
|
0.00
|
0.00
|
0.00
-100.00%
|
0.00
|
| Change In Working Capital |
|
-10.08
-185.09%
|
-3.54
+80.20%
|
-17.85
+59.88%
|
-44.50
|
| Change In Receivables |
|
-21.28
-230.20%
|
16.34
+295.33%
|
-8.37
-6.95%
|
-7.82
|
| Changes In Account Receivables |
|
-21.28
-230.20%
|
16.34
+295.33%
|
-8.37
-6.95%
|
-7.82
|
| Change In Inventory |
|
3.21
+295.19%
|
-1.64
+35.63%
|
-2.55
-198.88%
|
2.58
|
| Change In Prepaid Assets |
|
-0.33
-132.50%
|
1.00
+21.95%
|
0.82
-65.36%
|
2.37
|
| Change In Payables And Accrued Expense |
|
12.70
+173.83%
|
-17.20
-141.14%
|
-7.13
+81.13%
|
-37.80
|
| Change In Accrued Expense |
|
13.15
+183.13%
|
-15.82
-108.66%
|
-7.58
+77.07%
|
-33.06
|
| Change In Payable |
|
-0.45
+67.17%
|
-1.38
-407.35%
|
0.45
+109.48%
|
-4.73
|
| Change In Account Payable |
|
-0.45
+67.17%
|
-1.38
-407.35%
|
0.45
+109.48%
|
-4.73
|
| Change In Other Working Capital |
|
-1.80
-13.74%
|
-1.59
-32.80%
|
-1.20
-29.89%
|
-0.92
|
| Change In Other Current Assets |
|
-0.17
-120.10%
|
0.82
-45.88%
|
1.52
+176.54%
|
-1.98
|
| Change In Other Current Liabilities |
|
-2.41
-90.37%
|
-1.27
-34.79%
|
-0.94
-2.06%
|
-0.92
|
| Investing Cash Flow |
|
-36.19
-77.06%
|
-20.44
-6.87%
|
-19.12
-369.21%
|
7.10
|
| Cash Flow From Continuing Investing Activities |
|
-36.19
-77.06%
|
-20.44
-6.87%
|
-19.12
-369.21%
|
7.10
|
| Net PPE Purchase And Sale |
|
-0.07
-26.79%
|
-0.06
+60.00%
|
-0.14
|
0.00
|
| Purchase Of PPE |
|
-0.07
-26.79%
|
-0.06
+60.00%
|
-0.14
|
0.00
|
| Capital Expenditure |
|
-0.07
-26.79%
|
-0.06
+99.56%
|
-12.64
-80.57%
|
-7.00
|
| Net Investment Purchase And Sale |
|
-36.12
-77.20%
|
-20.38
-214.29%
|
-6.49
-145.98%
|
14.10
|
| Purchase Of Investment |
|
-108.14
-41.86%
|
-76.23
-220.12%
|
-23.81
-392.41%
|
-4.84
|
| Sale Of Investment |
|
72.02
+28.96%
|
55.85
+222.30%
|
17.33
-8.51%
|
18.94
|
| Net Intangibles Purchase And Sale |
|
0.00
|
0.00
+100.00%
|
-12.50
-78.57%
|
-7.00
|
| Purchase Of Intangibles |
|
0.00
|
0.00
+100.00%
|
-12.50
-78.57%
|
-7.00
|
| Financing Cash Flow |
|
-45.20
-33.54%
|
-33.85
|
0.00
-100.00%
|
12.22
|
| Cash Flow From Continuing Financing Activities |
|
-45.20
-33.54%
|
-33.85
|
0.00
-100.00%
|
12.22
|
| Net Issuance Payments Of Debt |
|
-44.44
-33.33%
|
-33.33
|
0.00
|
0.00
|
| Issuance Of Debt |
|
—
|
—
|
0.00
|
0.00
|
| Repayment Of Debt |
|
-44.44
-33.33%
|
-33.33
|
0.00
|
0.00
|
| Long Term Debt Issuance |
|
—
|
—
|
0.00
|
0.00
|
| Long Term Debt Payments |
|
-44.44
-33.33%
|
-33.33
|
0.00
|
0.00
|
| Net Long Term Debt Issuance |
|
-44.44
-33.33%
|
-33.33
|
0.00
|
0.00
|
| Net Common Stock Issuance |
|
—
|
0.00
|
0.00
-100.00%
|
12.50
|
| Proceeds From Stock Option Exercised |
|
0.13
-13.33%
|
0.15
|
0.00
|
0.00
|
| Net Other Financing Charges |
|
-0.89
-33.33%
|
-0.67
|
—
|
-0.28
|
| Changes In Cash |
|
-39.58
-157.61%
|
-15.37
-294.90%
|
7.88
+125.26%
|
3.50
|
| Beginning Cash Position |
|
71.31
-17.73%
|
86.68
+10.01%
|
78.79
+4.65%
|
75.29
|
| End Cash Position |
|
31.73
-55.51%
|
71.31
-17.73%
|
86.68
+10.01%
|
78.79
|
| Free Cash Flow |
|
41.73
+7.38%
|
38.86
+170.46%
|
14.37
+162.95%
|
-22.83
|
| Interest Paid Supplemental Data |
|
5.82
-45.97%
|
10.77
-7.39%
|
11.63
+12.69%
|
10.32
|
| Income Tax Paid Supplemental Data |
|
1.52
+25.12%
|
1.22
+65.26%
|
0.74
+91.93%
|
0.38
|
| Common Stock Issuance |
|
—
|
0.00
|
0.00
-100.00%
|
12.50
|
| Issuance Of Capital Stock |
|
—
|
0.00
|
0.00
-100.00%
|
12.50
|
SEC Filings
Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.
- 10-Q2026-05-07 View
- 8-K2026-05-07 View
- 10-K2026-02-26 View
- 8-K2026-02-26 View
- 42026-02-20 View
- 42026-02-20 View
- 42026-02-20 View
- 42026-01-08 View
- 42026-01-08 View
- 42026-01-08 View
- 42025-11-13 View
- 10-Q2025-11-06 View
- 8-K2025-11-06 View
- 10-Q2025-08-07 View
- 8-K2025-08-07 View
- 42025-07-22 View
- 42025-07-10 View
- 42025-07-10 View
- 42025-07-10 View
- 8-K2025-06-24 View
Trades
| Date | User | Broker | Pattern | Type | Position Size | Entry Price | Trade P&L | Status |
|---|
Posts
| Published | Title | Author | Category |
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