Symbols / PLRX Stock $1.26 -2.33% Pliant Therapeutics, Inc.

Healthcare • Biotechnology • United States • NMS
PLRX (Stock) Chart
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About

Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company's lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of avß8 and avß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

Stock Fundamentals
Scroll to Statements
Market Cap 78.01M Enterprise Value -83.83M Income -149.34M Sales — Book/sh 2.95 Cash/sh 3.08
Dividend Yield — Payout 0.00% Employees 49 IPO — P/E — Forward P/E -1.04
PEG — P/S — P/B 0.43 P/C — EV/EBITDA 0.56 EV/Sales —
Quick Ratio 11.72 Current Ratio 12.00 Debt/Eq 16.06 LT Debt/Eq — EPS (ttm) -2.43 EPS next Y -1.22
EPS Growth — Revenue Growth — Earnings 2026-05-07 ROA -30.15% ROE -61.55% ROIC —
Gross Margin 0.00% Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 61.91M Shs Float 60.23M Short Float 6.66%
Short Ratio 7.56 Short Interest — 52W High 1.95 52W Low 1.09 Beta 1.25 Avg Volume 665.35K
Volume 432.23K Target Price $2.67 Recom None Prev Close $1.29 Price $1.26 Change -2.33%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$2.67
Mean price target
2. Current target
$1.26
Latest analyst target
3. DCF / Fair value
$-24.58
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.26
Low
$2.00
High
$3.00
Mean
$2.67

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-13 main Canaccord Genuity Hold → Hold $3
2026-03-12 main Piper Sandler Overweight → Overweight $3
2025-11-07 main RBC Capital Sector Perform → Sector Perform $2
2025-10-10 down JP Morgan Neutral → Underweight —
2025-08-08 main Piper Sandler Overweight → Overweight $4
2025-03-18 reit HC Wainwright & Co. Neutral → Neutral —
2025-03-04 reit HC Wainwright & Co. Neutral → Neutral —
2025-03-04 main Citigroup Neutral → Neutral $2
2025-03-04 main RBC Capital Sector Perform → Sector Perform $3
2025-03-04 main Wells Fargo Equal-Weight → Equal-Weight $3
2025-03-04 down Needham Buy → Hold $10
2025-03-03 down Leerink Partners Outperform → Market Perform $2
2025-02-14 reit HC Wainwright & Co. Neutral → Neutral —
2025-02-14 reit Needham Buy → Buy $10
2025-02-10 down JP Morgan Overweight → Neutral —
2025-02-10 down RBC Capital Outperform → Sector Perform $4
2025-02-10 down Canaccord Genuity Buy → Hold $4
2025-02-10 down Wells Fargo Overweight → Equal-Weight $4
2025-02-10 down Citigroup Buy → Neutral $4
2025-02-10 main Needham Buy → Buy $10
News
RSS: Latest PLRX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-01-20 COULIE BERNARD J Chief Executive Officer — 89,375 $1.28 $114,400
2026-01-20 CUMMINGS KEITH LAMONT Chief Financial Officer — 24,002 $1.28 $30,723
2026-01-20 CHEUNG LILY Officer — 7,534 $1.28 $9,644
2026-01-20 KUO MINNIE Chief Operating Officer — 6,917 $1.28 $8,854
2025-01-23 LEFEBVRE ERIC Officer — 45,650 $0.00 $0
2025-01-23 HULL JOHANNES P. Officer — 40,150 $0.00 $0
2025-01-23 COULIE BERNARD J Chief Executive Officer — 162,500 $0.00 $0
2025-01-23 CUMMINGS KEITH LAMONT Chief Financial Officer — 56,650 $0.00 $0
2025-01-23 OUIMETTE MICHAEL General Counsel — 35,000 $0.00 $0
2025-01-23 CHEUNG LILY Officer — 25,875 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
-100.00%
1.58
-83.69%
9.69
Operating Revenue
0.00
0.00
-100.00%
1.58
-83.69%
9.69
Operating Expense
156.37
-31.52%
228.37
+22.96%
185.72
+35.68%
136.88
Research And Development
109.16
-35.53%
169.31
+32.48%
127.80
+31.84%
96.94
Selling General And Administration
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
General And Administrative Expense
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
Other Gand A
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
Total Expenses
156.37
-31.52%
228.37
+22.96%
185.72
+35.68%
136.88
Operating Income
-156.37
+31.52%
-228.37
-24.01%
-184.15
-44.77%
-127.20
Total Operating Income As Reported
-156.37
+31.52%
-228.37
-24.01%
-184.15
-44.77%
-127.20
EBITDA
-145.09
+29.28%
-205.16
-29.66%
-158.23
-31.08%
-120.71
Normalized EBITDA
-143.26
+30.17%
-205.16
-29.66%
-158.23
-31.08%
-120.71
Reconciled Depreciation
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
EBIT
-146.78
+29.19%
-207.28
-29.49%
-160.07
-30.64%
-122.53
Total Unusual Items
-1.83
0.00
—
—
Total Unusual Items Excluding Goodwill
-1.83
0.00
—
—
Special Income Charges
-1.83
0.00
—
—
Other Special Charges
1.83
—
—
—
Net Income
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Pretax Income
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Non Operating Interest Income Expense
8.86
-50.96%
18.06
-20.82%
22.81
+488.01%
3.88
Interest Expense Non Operating
2.56
-15.38%
3.02
+138.67%
1.27
+60.18%
0.79
Net Interest Income
8.86
-50.96%
18.06
-20.82%
22.81
+488.01%
3.88
Interest Expense
2.56
-15.38%
3.02
+138.67%
1.27
+60.18%
0.79
Interest Income Non Operating
11.42
-45.86%
21.09
-12.42%
24.08
+415.55%
4.67
Interest Income
11.42
-45.86%
21.09
-12.42%
24.08
+415.55%
4.67
Other Income Expense
-1.83
—
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income From Continuing Operation Net Minority Interest
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income From Continuing And Discontinued Operation
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income Continuous Operations
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Normalized Income
-147.52
+29.86%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income Common Stockholders
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Diluted EPS
-2.43
+29.97%
-3.47
-26.18%
-2.75
+6.46%
-2.94
Basic EPS
-2.43
+29.97%
-3.47
-26.18%
-2.75
+6.46%
-2.94
Basic Average Shares
61.37
+1.37%
60.54
+3.10%
58.72
+39.75%
42.02
Diluted Average Shares
61.37
+1.37%
60.54
+3.10%
58.72
+39.75%
42.02
Diluted NI Availto Com Stockholders
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Total Other Finance Cost
—
—
—
—
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
225.23
-43.26%
396.95
-22.49%
512.15
+46.07%
350.61
Current Assets
196.45
-45.77%
362.26
-28.34%
505.50
+48.54%
340.31
Cash Cash Equivalents And Short Term Investments
190.94
-46.32%
355.72
-28.03%
494.25
+49.23%
331.19
Cash And Cash Equivalents
45.45
-36.16%
71.19
+12.58%
63.23
+87.72%
33.69
Other Short Term Investments
145.50
-48.86%
284.54
-33.98%
431.01
+44.88%
297.50
Receivables
0.82
-64.25%
2.30
-23.19%
3.00
-4.68%
3.14
Accounts Receivable
—
—
0.00
-100.00%
1.98
Taxes Receivable
—
—
0.00
-100.00%
0.08
Accrued Interest Receivable
0.82
-64.25%
2.30
-23.19%
3.00
+178.01%
1.08
Prepaid Assets
3.55
-12.91%
4.08
-41.69%
6.99
+20.34%
5.81
Assets Held For Sale Current
1.04
0.00
—
—
Other Current Assets
0.09
-43.56%
0.16
-87.19%
1.27
+635.26%
0.17
Total Non Current Assets
28.78
-17.02%
34.69
+421.42%
6.65
-35.43%
10.30
Net PPE
26.91
-17.89%
32.77
+585.81%
4.78
-51.78%
9.91
Gross PPE
37.77
-13.31%
43.58
+223.74%
13.46
-19.64%
16.75
Accumulated Depreciation
-10.87
-0.57%
-10.81
-24.48%
-8.68
-26.91%
-6.84
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
2.94
+1.98%
2.88
+2222.58%
0.12
+313.33%
0.03
Construction In Progress
0.15
-55.78%
0.35
+565.38%
0.05
-21.21%
0.07
Other Properties
32.53
-14.91%
38.23
+228.98%
11.62
-22.54%
15.00
Leases
2.16
+1.79%
2.12
+27.36%
1.66
+0.79%
1.65
Other Non Current Assets
1.87
-2.24%
1.92
+2.29%
1.87
+375.63%
0.39
Total Liabilities Net Minority Interest
44.02
-52.60%
92.87
+140.73%
38.58
+3.51%
37.27
Current Liabilities
16.36
-50.73%
33.22
+16.46%
28.52
+19.28%
23.91
Payables And Accrued Expenses
6.62
-69.24%
21.52
+18.49%
18.16
+27.41%
14.26
Payables
0.48
-91.95%
5.96
+31.54%
4.53
+186.77%
1.58
Accounts Payable
0.48
-91.95%
5.96
+31.54%
4.53
+186.77%
1.58
Current Accrued Expenses
6.14
-60.54%
15.56
+14.15%
13.63
+7.55%
12.68
Pensionand Other Post Retirement Benefit Plans Current
8.30
-25.61%
11.15
+23.36%
9.04
+25.58%
7.20
Current Debt And Capital Lease Obligation
1.45
+166.97%
0.54
-58.88%
1.32
-46.36%
2.46
Current Capital Lease Obligation
1.45
+166.97%
0.54
-58.88%
1.32
-46.36%
2.46
Current Deferred Liabilities
—
—
—
—
Total Non Current Liabilities Net Minority Interest
27.66
-53.63%
59.65
+493.30%
10.05
-24.73%
13.36
Long Term Debt And Capital Lease Obligation
27.66
-53.63%
59.65
+493.30%
10.05
-24.73%
13.36
Long Term Debt
—
30.21
+200.49%
10.05
+1.26%
9.93
Long Term Capital Lease Obligation
27.66
-6.05%
29.44
0.00
-100.00%
3.43
Non Current Deferred Liabilities
—
—
—
—
Stockholders Equity
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Common Stock Equity
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Capital Stock
0.01
+0.00%
0.01
+0.00%
0.01
+20.00%
0.01
Common Stock
0.01
+0.00%
0.01
+0.00%
0.01
+20.00%
0.01
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
61.45
+0.97%
60.86
+1.57%
59.92
+22.43%
48.94
Ordinary Shares Number
61.45
+0.97%
60.86
+1.57%
59.92
+22.43%
48.94
Additional Paid In Capital
1,040.61
+2.64%
1,013.81
+4.20%
972.97
+48.84%
653.71
Retained Earnings
-859.40
-21.03%
-710.05
-42.08%
-499.75
-47.67%
-338.41
Gains Losses Not Affecting Retained Earnings
-0.01
-104.67%
0.32
-6.96%
0.34
+117.62%
-1.96
Other Equity Adjustments
-0.01
-104.67%
0.32
-6.96%
0.34
+117.62%
-1.96
Total Equity Gross Minority Interest
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Total Capitalization
181.21
-45.79%
334.29
-30.88%
483.63
+49.61%
323.27
Working Capital
180.08
-45.27%
329.05
-31.01%
476.98
+50.75%
316.40
Invested Capital
181.21
-45.79%
334.29
-30.88%
483.63
+49.61%
323.27
Total Debt
29.11
-51.65%
60.19
+429.30%
11.37
-28.09%
15.81
Capital Lease Obligations
29.11
-2.92%
29.98
+2174.73%
1.32
-77.61%
5.89
Net Tangible Assets
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Tangible Book Value
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-128.34
+17.47%
-155.50
-33.64%
-116.36
-22.96%
-94.63
Cash Flow From Continuing Operating Activities
-128.34
+17.47%
-155.50
-33.64%
-116.36
-22.96%
-94.63
Net Income From Continuing Operations
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Depreciation Amortization Depletion
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Depreciation
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Depreciation And Amortization
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Other Non Cash Items
3.28
-5.04%
3.45
+44.39%
2.39
+28.63%
1.86
Stock Based Compensation
26.23
-30.28%
37.63
-15.41%
44.48
+96.84%
22.60
Operating Gains Losses
1.78
—
—
—
Gain Loss On Sale Of PPE
-0.04
0.00
—
—
Change In Working Capital
-15.94
-275.37%
9.09
+626.54%
1.25
-70.33%
4.22
Change In Receivables
—
0.00
-100.00%
1.98
+13120.00%
0.01
Changes In Account Receivables
—
0.00
-100.00%
1.98
+13120.00%
0.01
Change In Prepaid Assets
2.54
-46.13%
4.72
+226.29%
-3.73
-1170.41%
-0.29
Change In Payables And Accrued Expense
-17.65
-437.10%
5.24
-8.96%
5.75
-12.25%
6.55
Change In Accrued Expense
-12.17
-419.60%
3.81
+36.89%
2.78
-64.82%
7.90
Change In Payable
-5.48
-483.75%
1.43
-51.90%
2.97
+319.76%
-1.35
Change In Account Payable
-5.48
-483.75%
1.43
-51.90%
2.97
+319.76%
-1.35
Change In Other Current Assets
0.04
+200.00%
-0.04
0.00
-100.00%
0.20
Change In Other Current Liabilities
-0.88
-6.83%
-0.82
+70.15%
-2.75
-21.66%
-2.26
Investing Cash Flow
134.29
-4.31%
140.34
+210.49%
-127.01
+15.44%
-150.20
Cash Flow From Continuing Investing Activities
134.29
-4.31%
140.34
+210.49%
-127.01
+15.44%
-150.20
Net PPE Purchase And Sale
-0.22
+94.31%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Purchase Of PPE
-0.37
+90.28%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Sale Of PPE
0.15
0.00
—
—
Capital Expenditure
-0.37
+90.28%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Net Investment Purchase And Sale
134.51
-6.71%
144.19
+214.35%
-126.09
+15.06%
-148.44
Purchase Of Investment
-203.40
+3.73%
-211.28
+63.76%
-583.07
-79.01%
-325.72
Sale Of Investment
337.91
-4.94%
355.47
-22.21%
456.98
+157.78%
177.27
Financing Cash Flow
-31.70
-237.12%
23.12
-91.58%
274.40
+20.96%
226.85
Cash Flow From Continuing Financing Activities
-31.70
-237.12%
23.12
-91.58%
274.40
+20.96%
226.85
Net Issuance Payments Of Debt
-32.27
-262.06%
19.91
0.00
-100.00%
9.85
Issuance Of Debt
0.00
-100.00%
19.91
0.00
-100.00%
9.85
Repayment Of Debt
-32.27
0.00
—
—
Long Term Debt Issuance
0.00
-100.00%
19.91
0.00
-100.00%
9.85
Long Term Debt Payments
-32.27
0.00
—
—
Net Long Term Debt Issuance
-32.27
-262.06%
19.91
0.00
-100.00%
9.85
Net Common Stock Issuance
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Net Other Financing Charges
—
—
-0.85
-52.06%
-0.56
Changes In Cash
-25.74
-423.65%
7.95
-74.37%
31.03
+272.58%
-17.98
Beginning Cash Position
72.67
+12.29%
64.72
+92.13%
33.68
-34.80%
51.66
End Cash Position
46.93
-35.42%
72.67
+12.29%
64.72
+92.13%
33.68
Free Cash Flow
-128.71
+19.23%
-159.35
-35.87%
-117.28
-21.67%
-96.39
Interest Paid Supplemental Data
2.54
-3.09%
2.62
+128.02%
1.15
+86.83%
0.61
Amortization Of Securities
3.96
+57.61%
2.51
+150.30%
-4.99
-176.30%
-1.81
Common Stock Issuance
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Issuance Of Capital Stock
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Net Preferred Stock Issuance
—
—
—
—
Preferred Stock Issuance
—
—
—
—
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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