Symbols / PRQR Stock $1.63 -6.86% ProQR Therapeutics N.V.

Healthcare • Biotechnology • Netherlands • NCM
PRQR (Stock) Chart
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About

ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs. Its lead product candidate, AX-0810, targets na-taurocholate cotransporting polypeptide (NTCP) for the treatment of cholestatic diseases. The company also develops AX-2402, which targets methyl CpG binding protein 2 mutations for Rett syndrome; AX-2911, which targets PNPLA3 for metabolic dysfunction-associated steatohepatitis; and AX-1412, which targets the B4GALT1 gene for cardiovascular diseases. It has a research and collaboration agreement with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.

Stock Fundamentals
Scroll to Statements
Market Cap 171.74M Enterprise Value 107.93M Income -42.18M Sales 16.35M Book/sh 0.55 Cash/sh 0.88
Dividend Yield — Payout 0.00% Employees 186 IPO — P/E — Forward P/E -3.47
PEG — P/S 10.51 P/B 2.97 P/C — EV/EBITDA -2.54 EV/Sales 6.60
Quick Ratio 3.00 Current Ratio 3.09 Debt/Eq 32.33 LT Debt/Eq — EPS (ttm) -0.47 EPS next Y -0.47
EPS Growth — Revenue Growth 6.10% Earnings 2026-05-07 ROA -19.35% ROE -61.17% ROIC —
Gross Margin 100.00% Oper. Margin -192.90% Profit Margin -258.05% Shs Outstand 105.36M Shs Float 64.35M Short Float 2.33%
Short Ratio 4.24 Short Interest — 52W High 3.10 52W Low 1.33 Beta 0.09 Avg Volume 470.07K
Volume 710.40K Target Price $8.88 Recom Strong_buy Prev Close $1.75 Price $1.63 Change -6.86%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$8.88
Mean price target
2. Current target
$1.63
Latest analyst target
3. DCF / Fair value
$-5.47
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.63
Low
$4.00
High
$14.00
Mean
$8.88

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-04-09 main Chardan Capital Buy → Buy $4
2025-11-04 main Chardan Capital Buy → Buy $4
2025-08-08 main Chardan Capital Buy → Buy $4
2025-06-27 reit Cantor Fitzgerald Overweight → Overweight $8
2025-06-27 reit JMP Securities Market Outperform → Market Outperform $8
2025-05-13 main Oppenheimer Outperform → Outperform $9
2025-04-29 init Evercore ISI Group — → Outperform $5
2025-03-14 main Chardan Capital Buy → Buy $4
2025-03-14 main HC Wainwright & Co. Buy → Buy $12
2025-02-12 init Jones Trading — → Buy $11
2024-12-12 reit JMP Securities Market Outperform → Market Outperform $8
2024-12-12 main Chardan Capital Buy → Buy $4
2024-12-12 reit HC Wainwright & Co. Buy → Buy $10
2024-11-08 main HC Wainwright & Co. Buy → Buy $10
2024-10-29 up Raymond James Outperform → Strong Buy $14
2024-05-10 main Chardan Capital Buy → Buy $3
2024-05-10 reit HC Wainwright & Co. Buy → Buy $5
2024-04-18 main Citigroup Neutral → Neutral $2
2024-03-14 reit HC Wainwright & Co. Buy → Buy $5
2024-03-14 main Chardan Capital Buy → Buy $3
News
RSS: Latest PRQR news
Insider Transactions

No recent insider transactions.

Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
15.91
-15.86%
18.91
+190.22%
6.51
+81.25%
3.59
Operating Revenue
15.91
-15.86%
18.91
+190.22%
6.51
+81.25%
3.59
Operating Expense
59.35
+20.20%
49.38
+19.55%
41.30
-39.92%
68.75
Research And Development
44.73
+23.04%
36.36
+44.57%
25.15
-50.56%
50.87
Selling General And Administration
15.06
+10.24%
13.66
-15.86%
16.24
-12.95%
18.65
General And Administrative Expense
15.06
+10.24%
13.66
-15.86%
16.24
-12.95%
18.65
Other Gand A
15.06
+10.24%
13.66
-15.86%
16.24
-12.95%
18.65
Other Operating Expenses
-0.44
+31.09%
-0.64
-700.00%
-0.08
+89.54%
-0.77
Total Expenses
59.35
+20.20%
49.38
+19.55%
41.30
-39.92%
68.75
Operating Income
-43.45
-42.58%
-30.47
+12.41%
-34.79
+46.61%
-65.16
Total Operating Income As Reported
-43.45
-42.58%
-30.47
+4.35%
-31.86
+51.11%
-65.16
EBITDA
-38.53
-59.74%
-24.12
-0.10%
-24.10
+57.32%
-56.46
Normalized EBITDA
-38.17
-58.30%
-24.11
+16.07%
-28.73
+51.98%
-59.83
Reconciled Depreciation
2.70
-2.10%
2.76
+9.87%
2.51
-0.32%
2.52
EBIT
-41.24
-53.39%
-26.88
-1.03%
-26.61
+54.88%
-58.98
Total Unusual Items
-0.36
-5014.29%
-0.01
-100.15%
4.63
+37.63%
3.37
Total Unusual Items Excluding Goodwill
-0.36
-5014.29%
-0.01
-100.15%
4.63
+37.63%
3.37
Special Income Charges
0.00
0.00
-100.00%
4.89
+451.73%
-1.39
Other Special Charges
—
—
-1.87
-234.24%
1.39
Net Income
-42.18
-51.94%
-27.76
+1.27%
-28.12
+56.35%
-64.42
Pretax Income
-42.16
-50.80%
-27.96
-0.53%
-27.81
+56.62%
-64.11
Net Non Operating Interest Income Expense
1.40
-35.42%
2.17
+56.40%
1.39
+127.68%
-5.02
Interest Expense Non Operating
0.93
-13.74%
1.08
-10.47%
1.20
-76.54%
5.13
Net Interest Income
1.40
-35.42%
2.17
+56.40%
1.39
+127.68%
-5.02
Interest Expense
0.93
-13.74%
1.08
-10.47%
1.20
-76.54%
5.13
Interest Income Non Operating
2.33
-28.24%
3.25
+25.38%
2.59
+2346.23%
0.11
Interest Income
2.33
-28.24%
3.25
+25.38%
2.59
+2346.23%
0.11
Other Income Expense
-0.12
-136.39%
0.34
-93.95%
5.59
-7.99%
6.07
Other Non Operating Income Expenses
0.23
-31.88%
0.34
-63.80%
0.95
-64.87%
2.71
Gain On Sale Of Security
-0.36
-5014.29%
-0.01
+97.25%
-0.26
-105.36%
4.76
Gain On Sale Of Business
0.00
0.00
-100.00%
0.09
0.00
Tax Provision
0.02
+109.64%
-0.20
-152.56%
-0.08
-181.25%
0.10
Tax Rate For Calcs
0.00
+2900.00%
0.00
+133.33%
0.00
-98.57%
0.00
Tax Effect Of Unusual Items
-0.08
-153328.57%
-0.00
-100.35%
0.01
-98.03%
0.71
Net Income Including Noncontrolling Interests
-42.18
-51.94%
-27.76
-0.10%
-27.73
+56.80%
-64.20
Net Income From Continuing Operation Net Minority Interest
-42.18
-51.94%
-27.76
+1.27%
-28.12
+56.35%
-64.42
Net Income From Continuing And Discontinued Operation
-42.18
-51.94%
-27.76
+1.27%
-28.12
+56.35%
-64.42
Net Income Continuous Operations
-42.18
-51.94%
-27.76
-0.10%
-27.73
+56.80%
-64.20
Minority Interests
0.00
0.00
+100.00%
-0.38
-74.55%
-0.22
Normalized Income
-41.90
-50.96%
-27.76
+15.22%
-32.74
+51.20%
-67.08
Net Income Common Stockholders
-42.18
-51.94%
-27.76
+1.27%
-28.12
+56.35%
-64.42
Diluted EPS
—
-0.32
+8.57%
-0.35
+61.11%
-0.90
Basic EPS
—
-0.32
+8.57%
-0.35
+61.11%
-0.90
Basic Average Shares
—
86.09
+6.26%
81.01
+13.08%
71.64
Diluted Average Shares
—
86.09
+6.26%
81.01
+13.08%
71.64
Diluted NI Availto Com Stockholders
-42.18
-51.94%
-27.76
+1.27%
-28.12
+56.35%
-64.42
Earnings From Equity Interest
—
0.00
0.00
+100.00%
-0.01
Gain On Sale Of PPE
0.00
0.00
-100.00%
2.93
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
112.76
-32.87%
167.96
+21.81%
137.88
-19.52%
171.32
Current Assets
100.13
-34.92%
153.84
+27.16%
120.99
-21.67%
154.46
Cash Cash Equivalents And Short Term Investments
92.41
-38.15%
149.41
+25.63%
118.92
+25.48%
94.78
Cash And Cash Equivalents
92.41
-38.15%
149.41
+25.63%
118.92
+25.48%
94.78
Cash Equivalents
54.66
-27.33%
75.21
+27.15%
59.15
0.00
Cash Financial
37.76
-49.12%
74.20
+24.13%
59.77
-36.93%
94.78
Receivables
5.09
+150.91%
2.03
+59.86%
1.27
-97.78%
57.24
Accounts Receivable
3.36
0.00
—
—
Other Receivables
0.81
-39.04%
1.34
+79.46%
0.74
-98.68%
56.63
Taxes Receivable
0.91
+32.32%
0.69
+31.93%
0.52
-13.84%
0.61
Prepaid Assets
2.63
+9.00%
2.41
+203.91%
0.79
-67.62%
2.45
Total Non Current Assets
12.63
-10.51%
14.11
-16.48%
16.90
+0.21%
16.86
Net PPE
12.63
-10.51%
14.11
-16.48%
16.90
+4.05%
16.24
Gross PPE
33.29
+3.80%
32.07
-0.07%
32.09
+10.23%
29.11
Accumulated Depreciation
-20.66
-15.05%
-17.96
-18.17%
-15.20
-18.03%
-12.87
Properties
24.19
+1.67%
23.79
-3.96%
24.77
+8.36%
22.86
Other Properties
9.10
+9.93%
8.28
+13.11%
7.32
+17.05%
6.25
Investments And Advances
0.00
0.00
0.00
-100.00%
0.62
Long Term Equity Investment
—
—
—
0.00
Total Liabilities Net Minority Interest
63.38
-20.17%
79.40
-17.72%
96.49
-7.79%
104.64
Current Liabilities
32.44
-16.61%
38.90
+13.74%
34.20
+62.96%
20.99
Payables And Accrued Expenses
0.30
-80.05%
1.49
-53.31%
3.20
+111.92%
1.51
Payables
0.30
-80.05%
1.49
-53.31%
3.20
+111.92%
1.51
Accounts Payable
0.30
+1762.50%
0.02
-98.96%
1.54
+293.11%
0.39
Pensionand Other Post Retirement Benefit Plans Current
—
—
—
—
Total Tax Payable
0.00
-100.00%
1.48
-10.91%
1.66
+48.39%
1.12
Current Debt And Capital Lease Obligation
6.42
+4.36%
6.15
+280.98%
1.61
-58.48%
3.89
Current Debt
4.87
+6.33%
4.58
—
2.50
Other Current Borrowings
4.87
+6.33%
4.58
—
2.50
Current Capital Lease Obligation
1.54
-1.40%
1.57
-2.91%
1.61
+16.37%
1.39
Current Deferred Liabilities
17.55
-20.01%
21.94
+6.68%
20.57
+264.63%
5.64
Current Deferred Revenue
17.55
-20.01%
21.94
+6.68%
20.57
+264.63%
5.64
Other Current Liabilities
8.17
-12.27%
9.32
+5.63%
8.82
-11.36%
9.95
Total Non Current Liabilities Net Minority Interest
30.94
-23.59%
40.50
-34.99%
62.29
-25.54%
83.65
Long Term Debt And Capital Lease Obligation
9.55
-13.73%
11.07
-38.92%
18.12
+0.20%
18.08
Long Term Debt
—
—
4.29
+0.49%
4.27
Long Term Capital Lease Obligation
9.55
-13.73%
11.07
-19.97%
13.83
+0.11%
13.81
Non Current Deferred Liabilities
21.39
-27.30%
29.43
-33.37%
44.17
-32.63%
65.57
Non Current Deferred Revenue
21.39
-27.30%
29.43
-33.37%
44.17
-32.63%
65.57
Stockholders Equity
49.37
-44.25%
88.56
+113.96%
41.39
-38.28%
67.06
Common Stock Equity
49.37
-44.25%
88.56
+113.96%
41.39
-38.28%
67.06
Capital Stock
4.31
+0.00%
4.31
+27.83%
3.37
+0.00%
3.37
Common Stock
4.31
+0.00%
4.31
+27.83%
3.37
+0.00%
3.37
Share Issued
107.71
+0.00%
107.71
+27.85%
84.25
+0.00%
84.25
Ordinary Shares Number
105.36
+0.14%
105.21
+29.33%
81.35
+0.67%
80.82
Treasury Shares Number
2.35
-5.95%
2.50
-13.66%
2.89
-15.63%
3.43
Additional Paid In Capital
483.88
+0.01%
483.81
+17.18%
412.89
+0.09%
412.54
Retained Earnings
-467.51
-9.45%
-427.16
-6.56%
-400.85
-5.73%
-379.11
Gains Losses Not Affecting Retained Earnings
28.69
+3.96%
27.60
+6.24%
25.98
-14.17%
30.26
Minority Interest
0.00
0.00
0.00
+100.00%
-0.38
Total Equity Gross Minority Interest
49.37
-44.25%
88.56
+113.96%
41.39
-37.93%
66.68
Total Capitalization
49.37
-44.25%
88.56
+93.86%
45.68
-35.96%
71.34
Working Capital
67.69
-41.11%
114.94
+32.45%
86.78
-34.98%
133.47
Invested Capital
54.25
-41.76%
93.14
+103.89%
45.68
-38.13%
73.84
Total Debt
15.96
-7.27%
17.22
-12.76%
19.73
-10.18%
21.97
Capital Lease Obligations
11.09
-12.21%
12.63
-18.18%
15.44
+1.59%
15.20
Net Tangible Assets
49.37
-44.25%
88.56
+113.96%
41.39
-38.28%
67.06
Tangible Book Value
49.37
-44.25%
88.56
+113.96%
41.39
-38.28%
67.06
Investmentin Financial Assets
0.00
0.00
0.00
-100.00%
0.62
Investmentsin Associatesat Cost
—
—
—
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-52.79
-45.06%
-36.39
-268.89%
21.55
+131.45%
-68.51
Cash Flow From Continuing Operating Activities
-52.79
-45.06%
-36.39
-268.89%
21.55
+131.45%
-68.51
Net Income From Continuing Operations
-42.18
-51.94%
-27.76
-0.10%
-27.73
+56.80%
-64.20
Depreciation Amortization Depletion
2.70
-2.10%
2.76
+9.87%
2.51
-0.32%
2.52
Depreciation
2.70
-2.10%
2.76
+9.87%
2.51
-0.32%
2.52
Depreciation And Amortization
2.70
-2.10%
2.76
+9.87%
2.51
-0.32%
2.52
Other Non Cash Items
-1.49
+47.03%
-2.81
+53.31%
-6.01
-463.48%
1.65
Stock Based Compensation
4.01
+57.78%
2.54
-18.09%
3.11
+8.26%
2.87
Deferred Tax
0.02
+109.64%
-0.20
-152.56%
-0.08
-181.25%
0.10
Deferred Income Tax
0.02
+109.64%
-0.20
-152.56%
-0.08
-181.25%
0.10
Operating Gains Losses
-0.23
+31.88%
-0.34
+68.17%
-1.08
+59.93%
-2.71
Gain Loss On Investment Securities
-0.23
+31.88%
-0.34
+63.80%
-0.95
+64.87%
-2.71
Change In Working Capital
-17.42
-31.31%
-13.26
-127.09%
48.96
+1080.89%
-4.99
Change In Other Working Capital
-17.42
-31.31%
-13.26
-127.09%
48.96
+1080.89%
-4.99
Investing Cash Flow
-1.02
+74.96%
-4.07
-195.21%
4.28
+709.40%
-0.70
Cash Flow From Continuing Investing Activities
-1.02
+74.96%
-4.07
-195.21%
4.28
+709.40%
-0.70
Net PPE Purchase And Sale
-1.02
+28.07%
-1.42
-8.16%
-1.31
-86.75%
-0.70
Purchase Of PPE
-1.02
+28.07%
-1.42
-3.43%
-1.37
-93.64%
-0.71
Sale Of PPE
0.00
0.00
-100.00%
0.06
+900.00%
0.01
Capital Expenditure
-1.02
+28.07%
-1.42
-3.43%
-1.37
-93.64%
-0.71
Net Investment Purchase And Sale
0.00
0.00
0.00
0.00
Purchase Of Investment
0.00
+100.00%
-17.00
0.00
0.00
Sale Of Investment
0.00
-100.00%
17.00
0.00
0.00
Gain Loss On Sale Of Business
0.00
0.00
+100.00%
-0.13
0.00
Net Intangibles Purchase And Sale
0.00
0.00
-100.00%
7.94
0.00
Net Other Investing Changes
—
-2.65
-12.93%
-2.35
—
Financing Cash Flow
-1.84
-102.61%
70.28
+3189.05%
-2.27
+92.64%
-30.89
Cash Flow From Continuing Financing Activities
-1.84
-102.61%
70.28
+3189.05%
-2.27
+92.64%
-30.89
Net Issuance Payments Of Debt
-1.91
-20.42%
-1.58
+39.83%
-2.63
+94.16%
-45.05
Issuance Of Debt
—
—
0.00
0.00
Repayment Of Debt
-1.91
-20.42%
-1.58
+39.83%
-2.63
+94.16%
-45.05
Long Term Debt Issuance
—
—
0.00
0.00
Long Term Debt Payments
-1.91
-20.42%
-1.58
+39.83%
-2.63
+94.16%
-45.05
Net Long Term Debt Issuance
-1.91
-20.42%
-1.58
+39.83%
-2.63
+94.16%
-45.05
Net Common Stock Issuance
0.00
-100.00%
71.64
0.00
-100.00%
14.12
Proceeds From Stock Option Exercised
0.07
-69.06%
0.22
-37.01%
0.35
+941.18%
0.03
Changes In Cash
-55.65
-286.67%
29.81
+26.58%
23.55
+123.53%
-100.10
Effect Of Exchange Rate Changes
-1.35
-300.30%
0.67
+12.35%
0.60
-91.85%
7.35
Beginning Cash Position
149.41
+25.63%
118.92
+25.48%
94.78
-49.46%
187.52
End Cash Position
92.41
-38.15%
149.41
+25.63%
118.92
+25.48%
94.78
Free Cash Flow
-53.81
-42.32%
-37.81
-287.40%
20.18
+129.15%
-69.22
Common Stock Issuance
0.00
-100.00%
71.64
0.00
-100.00%
14.12
Earnings Losses From Equity Investments
—
0.00
0.00
-100.00%
0.01
Interest Paid CFO
-0.52
+32.73%
-0.77
+2.41%
-0.79
+79.00%
-3.76
Interest Received CFO
2.33
-28.24%
3.25
+25.38%
2.59
+2346.23%
0.11
Issuance Of Capital Stock
0.00
-100.00%
71.64
0.00
-100.00%
14.12
Sale Of Intangibles
0.00
0.00
-100.00%
7.94
0.00
Taxes Refund Paid
-0.02
-109.64%
0.20
+152.56%
0.08
+181.25%
-0.10
SEC Filings

No SEC filings found for this symbol (may be non-US or ticker not in SEC index).

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