Symbols / QNCX $1.37 +2.24% Quince Therapeutics, Inc.

Healthcare • Biotechnology • United States • NMS
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About

Quince Therapeutics, Inc., a biopharmaceutical company, focuses on acquiring, developing, and commercializing therapeutics for patients with debilitating and rare diseases. The company's lead asset candidature comprises EryDex for the treatment of rare pediatric neurodegenerative disease, including A-T, an inherited autosomal recessive neurodegenerative and immunodeficiency disorder caused by mutations in ATM gene. Its AIDE technology platform, a drug/device combination platform that uses an automated process to encapsulate a drug into a patient's own red blood cells, as well as consists of an automated equipment the RCL, a sterile single-use consumable treatment kit comprising kit medical devices, syringe kit, and process solutions. The company was formerly known as Cortexyme, Inc. and changed its name to Quince Therapeutics, Inc. in August 2022. The company was incorporated in 2012 and is headquartered in South San Francisco, California.

Fundamentals
Scroll to Statements
Market Cap 22.33M Enterprise Value 23.05M Income -83.98M Sales — Book/sh -6.41 Cash/sh 1.09
Dividend Yield — Payout 0.00% Employees 38 IPO — P/E — Forward P/E -1.17
PEG — P/S — P/B -0.21 P/C — EV/EBITDA -0.46 EV/Sales —
Quick Ratio 0.49 Current Ratio 0.53 Debt/Eq — LT Debt/Eq — EPS (ttm) -16.80 EPS next Y -1.17
EPS Growth — Revenue Growth — Earnings 2026-05-13 ROA -30.31% ROE — ROIC —
Gross Margin 0.00% Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 16.30M Shs Float 15.71M Short Float 27.67%
Short Ratio 0.39 Short Interest — 52W High 45.50 52W Low 0.80 Beta 1.33 Avg Volume 10.59M
Volume 1.49M Target Price $0.00 Recom None Prev Close $1.34 Price $1.37 Change 2.24%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
—
Mean price target
2. Current target
$1.37
Latest analyst target
3. DCF / Fair value
$-12.35
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.37
Low
—
High
—
Mean
—

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-30 down Citizens Market Outperform → Market Perform —
2026-01-30 down D. Boral Capital Buy → Hold —
2026-01-29 main D. Boral Capital Buy → Buy $5
2025-12-15 main D. Boral Capital Buy → Buy $5
2025-11-13 main D. Boral Capital Buy → Buy $4
2025-09-26 main D. Boral Capital Buy → Buy $4
2025-08-15 main D. Boral Capital Buy → Buy $4
2025-08-12 main JMP Securities Market Outperform → Market Outperform $8
2025-08-05 init JMP Securities — → Market Outperform $9
2025-07-17 main D. Boral Capital Buy → Buy $4
2025-06-13 main D. Boral Capital Buy → Buy $4
2025-06-04 main D. Boral Capital Buy → Buy $4
2025-03-25 main D. Boral Capital Buy → Buy $4
2025-03-24 init Oppenheimer — → Outperform $10
2025-02-05 main D. Boral Capital Buy → Buy $12
2025-01-02 main D. Boral Capital Buy → Buy $12
2024-12-18 init Brookline Capital — → Buy $9
2024-11-14 main D. Boral Capital Buy → Buy $12
2024-11-12 main D. Boral Capital Buy → Buy $12
2024-11-07 init Maxim Group — → Buy $6
News
RSS: Latest QNCX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2025-12-26 LUCA BENATTI Director — 50,000 $3.47 $173,500
2025-12-10 THYE DIRK Chief Executive Officer — 739,885 — —
2025-12-05 HANNAH BRENDAN Chief Operating Officer — 27,551 $0.55 $25,012
2025-06-18 RYAN CHARLES S President — 7,548 $1.20 $9,058
2025-06-18 THYE DIRK Chief Executive Officer — 150,944 $1.20 $181,133
2025-06-18 HANNAH BRENDAN Chief Operating Officer — 37,736 $1.20 $45,283
2024-08-30 THYE DIRK Chief Executive Officer — 154,500 $0.69 $107,375
2024-08-21 HANNAH BRENDAN Chief Operating Officer — 38,924 $0.58 $24,166
2024-08-20 RYAN CHARLES S President — 48,387 $0.65 $31,452
2024-06-04 HANNAH BRENDAN Chief Operating Officer — 56,061 $0.55 $30,834
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
50.43
+39.42%
36.17
+33.26%
27.14
-46.98%
51.19
Research And Development
35.38
+90.33%
18.59
+96.78%
9.45
-62.48%
25.18
Selling General And Administration
15.05
-14.41%
17.58
-0.65%
17.70
-31.97%
26.01
General And Administrative Expense
15.05
-14.41%
17.58
-0.65%
17.70
-31.97%
26.01
Other Gand A
15.05
-14.41%
17.58
-0.65%
17.70
-31.97%
26.01
Total Expenses
50.43
+39.42%
36.17
+33.26%
27.14
-46.98%
51.19
Operating Income
-50.43
-39.42%
-36.17
-33.26%
-27.14
+46.98%
-51.19
Total Operating Income As Reported
-58.07
-1.37%
-57.28
-65.47%
-34.62
+33.44%
-52.02
EBITDA
-50.29
-39.75%
-35.98
-34.17%
-26.82
+47.40%
-50.99
Normalized EBITDA
-20.26
-36.28%
-14.87
+23.13%
-19.34
+61.44%
-50.16
Reconciled Depreciation
0.14
-23.66%
0.19
-42.24%
0.32
+57.84%
0.20
EBIT
-50.43
-39.42%
-36.17
-33.26%
-27.14
+46.98%
-51.19
Total Unusual Items
-30.02
-42.19%
-21.11
-182.36%
-7.48
-806.42%
-0.82
Total Unusual Items Excluding Goodwill
-30.02
-42.19%
-21.11
-182.36%
-7.48
-806.42%
-0.82
Special Income Charges
-7.64
+63.82%
-21.11
-182.36%
-7.48
-806.42%
-0.82
Impairment Of Capital Assets
0.00
-100.00%
17.13
+190.34%
5.90
+615.15%
0.82
Restructuring And Mergern Acquisition
7.64
+91.69%
3.98
+152.53%
1.58
0.00
Net Income
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Pretax Income
-80.77
-42.34%
-56.74
-79.66%
-31.58
+39.20%
-51.94
Net Non Operating Interest Income Expense
1.24
-57.53%
2.93
-15.78%
3.48
+225.66%
1.07
Net Interest Income
1.24
-57.53%
2.93
-15.78%
3.48
+225.66%
1.07
Interest Income Non Operating
1.24
-57.53%
2.93
-15.78%
3.48
+225.66%
1.07
Interest Income
1.24
-57.53%
2.93
-15.78%
3.48
+225.66%
1.07
Other Income Expense
-31.58
-34.38%
-23.50
-196.79%
-7.92
-334.58%
-1.82
Other Non Operating Income Expenses
-1.56
+34.72%
-2.38
-442.05%
-0.44
+55.87%
-1.00
Gain On Sale Of Security
-22.38
—
—
—
Tax Provision
3.21
+3594.25%
0.09
+144.16%
-0.20
+30.63%
-0.28
Tax Rate For Calcs
0.00
+0.00%
0.00
+3287.10%
0.00
+12.73%
0.00
Tax Effect Of Unusual Items
-6.30
-42.19%
-4.43
-9463.86%
-0.05
-921.79%
-0.00
Net Income Including Noncontrolling Interests
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Net Income From Continuing Operation Net Minority Interest
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Net Income From Continuing And Discontinued Operation
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Net Income Continuous Operations
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Normalized Income
-60.26
-50.10%
-40.15
-67.61%
-23.95
+52.88%
-50.84
Net Income Common Stockholders
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Diluted EPS
—
-13.10
-55.95%
-8.40
+45.45%
-15.40
Basic EPS
—
-13.10
-55.95%
-8.40
+45.45%
-15.40
Basic Average Shares
—
4.33
+16.18%
3.72
+11.17%
3.35
Diluted Average Shares
—
4.33
+16.18%
3.72
+11.17%
3.35
Diluted NI Availto Com Stockholders
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
93.52
-18.30%
114.48
-31.82%
167.90
+61.58%
103.91
Current Assets
22.90
-48.01%
44.04
-43.14%
77.44
-17.40%
93.75
Cash Cash Equivalents And Short Term Investments
17.75
-56.47%
40.78
-45.66%
75.06
-16.77%
90.18
Cash And Cash Equivalents
5.81
-6.49%
6.21
-70.07%
20.75
-53.45%
44.58
Cash Equivalents
4.40
+18.91%
3.70
-80.75%
19.23
-52.62%
40.59
Cash Financial
1.41
-43.94%
2.51
+65.02%
1.52
-61.84%
3.99
Other Short Term Investments
11.94
-65.45%
34.57
-36.34%
54.31
+19.09%
45.60
Receivables
3.62
+310.66%
0.88
-11.18%
0.99
-1.00%
1.00
Taxes Receivable
3.62
+310.66%
0.88
-11.18%
0.99
-1.00%
1.00
Prepaid Assets
1.47
-35.78%
2.29
+74.90%
1.31
-42.88%
2.29
Other Current Assets
0.05
-35.71%
0.08
+3.70%
0.08
-70.65%
0.28
Total Non Current Assets
70.63
+0.26%
70.44
-22.13%
90.46
+790.18%
10.16
Net PPE
1.05
+28.91%
0.81
+31.34%
0.62
-9.50%
0.68
Gross PPE
1.89
+30.30%
1.45
+28.95%
1.13
+29.57%
0.87
Accumulated Depreciation
-0.84
-32.08%
-0.64
-26.04%
-0.51
-174.05%
-0.18
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
0.33
+14.04%
0.28
+30.14%
0.22
+1116.67%
0.02
Other Properties
1.53
+34.95%
1.13
+30.08%
0.87
+4.94%
0.83
Leases
0.04
+11.76%
0.03
-5.56%
0.04
+71.43%
0.02
Goodwill And Other Intangible Assets
67.82
+12.95%
60.05
-26.14%
81.30
+1277.92%
5.90
Goodwill
—
0.00
-100.00%
17.62
0.00
Other Intangible Assets
67.82
+12.95%
60.05
-5.70%
63.67
+979.19%
5.90
Investments And Advances
0.08
+0.00%
0.08
+0.00%
0.08
-97.82%
3.58
Non Current Accounts Receivable
1.68
-82.31%
9.51
+12.42%
8.46
—
Other Non Current Assets
—
—
0.01
—
Total Liabilities Net Minority Interest
129.24
+53.25%
84.33
+1.83%
82.82
+2396.71%
3.32
Current Liabilities
43.23
+493.93%
7.28
-23.97%
9.57
+211.89%
3.07
Payables And Accrued Expenses
12.51
+81.96%
6.87
+33.53%
5.15
+111.76%
2.43
Payables
2.22
-23.42%
2.90
+42.79%
2.03
+256.67%
0.57
Accounts Payable
2.22
-23.42%
2.90
+42.79%
2.03
+256.67%
0.57
Current Accrued Expenses
10.29
+159.00%
3.97
+27.48%
3.12
+67.38%
1.86
Current Debt And Capital Lease Obligation
18.14
+18796.88%
0.10
+50.00%
0.06
-85.87%
0.45
Current Debt
18.03
—
—
—
Other Current Borrowings
18.03
—
—
—
Current Capital Lease Obligation
0.12
+19.79%
0.10
+50.00%
0.06
-85.87%
0.45
Other Current Liabilities
12.58
+3983.44%
0.31
-92.94%
4.36
+2256.76%
0.18
Total Non Current Liabilities Net Minority Interest
86.01
+11.62%
77.05
+5.20%
73.24
+29433.87%
0.25
Long Term Debt And Capital Lease Obligation
0.33
-97.76%
14.71
+7.02%
13.75
0.00
Long Term Debt
—
14.32
+6.64%
13.43
—
Long Term Capital Lease Obligation
0.33
-16.24%
0.39
+22.74%
0.32
0.00
Non Current Deferred Liabilities
0.00
-100.00%
4.96
-6.43%
5.30
+2038.71%
0.25
Non Current Deferred Taxes Liabilities
0.00
-100.00%
4.96
-6.43%
5.30
+2038.71%
0.25
Other Non Current Liabilities
53.53
-6.70%
57.38
+5.88%
54.19
—
Stockholders Equity
-35.71
-218.47%
30.15
-64.57%
85.08
-15.42%
100.59
Common Stock Equity
-35.71
-218.47%
30.15
-64.57%
85.08
-15.42%
100.59
Capital Stock
0.06
+25.00%
0.04
+2.33%
0.04
+19.44%
0.04
Common Stock
0.06
+25.00%
0.04
+2.33%
0.04
+19.44%
0.04
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
5.57
+26.64%
4.40
+2.39%
4.30
+18.92%
3.61
Ordinary Shares Number
5.57
+26.64%
4.40
+2.39%
4.30
+18.92%
3.61
Additional Paid In Capital
418.93
+3.03%
406.61
+1.24%
401.64
+3.22%
389.11
Retained Earnings
-460.45
-22.31%
-376.47
-17.78%
-319.64
-10.89%
-288.26
Gains Losses Not Affecting Retained Earnings
5.75
+16528.57%
-0.04
-101.15%
3.05
+1154.33%
-0.29
Other Equity Adjustments
5.75
+16528.57%
-0.04
-101.15%
3.05
+1154.33%
-0.29
Total Equity Gross Minority Interest
-35.71
-218.47%
30.15
-64.57%
85.08
-15.42%
100.59
Total Capitalization
-35.71
-180.32%
44.47
-54.86%
98.51
-2.07%
100.59
Working Capital
-20.33
-155.31%
36.76
-45.84%
67.87
-25.16%
90.68
Invested Capital
-17.69
-139.78%
44.47
-54.86%
98.51
-2.07%
100.59
Total Debt
18.47
+24.71%
14.81
+7.22%
13.81
+2949.45%
0.45
Net Debt
12.22
+50.66%
8.11
—
—
Capital Lease Obligations
0.45
-9.18%
0.49
+27.27%
0.39
-15.01%
0.45
Net Tangible Assets
-103.53
-246.28%
-29.90
-889.52%
3.79
-96.00%
94.69
Tangible Book Value
-103.53
-246.28%
-29.90
-889.52%
3.79
-96.00%
94.69
Available For Sale Securities
0.08
+0.00%
0.08
+0.00%
0.08
-97.82%
3.58
Derivative Product Liabilities
32.15
0.00
—
—
Investmentin Financial Assets
0.08
+0.00%
0.08
+0.00%
0.08
-97.82%
3.58
Non Current Accrued Expenses
—
—
53.60
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-41.42
-29.84%
-31.90
-74.42%
-18.29
+58.46%
-44.04
Cash Flow From Continuing Operating Activities
-41.42
-29.84%
-31.90
-74.42%
-18.29
+58.46%
-44.04
Net Income From Continuing Operations
-83.98
-47.78%
-56.83
-81.07%
-31.39
+39.25%
-51.66
Depreciation Amortization Depletion
0.14
-23.66%
0.19
-42.24%
0.32
+57.84%
0.20
Depreciation And Amortization
0.14
-23.66%
0.19
-42.24%
0.32
+57.84%
0.20
Other Non Cash Items
8.97
+57.55%
5.69
+241.37%
1.67
+632.91%
-0.31
Stock Based Compensation
5.11
+7.56%
4.75
-9.08%
5.22
-68.59%
16.62
Asset Impairment Charge
0.00
-100.00%
17.13
+187.13%
5.97
+520.81%
0.96
Deferred Tax
-4.96
0.00
—
—
Deferred Income Tax
-4.96
0.00
—
—
Operating Gains Losses
21.47
—
-0.04
-143.62%
0.09
Gain Loss On Investment Securities
21.47
—
—
—
Gain Loss On Sale Of PPE
—
0.00
+100.00%
-0.04
-143.62%
0.09
Change In Working Capital
12.84
+2753.51%
-0.48
-124.48%
1.98
+120.11%
-9.83
Change In Prepaid Assets
2.96
+272.82%
-1.71
-140.30%
4.25
+64.57%
2.58
Change In Payables And Accrued Expense
4.84
+142.53%
1.99
+188.23%
-2.26
+82.07%
-12.60
Change In Accrued Expense
5.78
+441.33%
1.07
+154.11%
-1.97
+70.39%
-6.66
Change In Payable
-0.94
-201.40%
0.93
+421.88%
-0.29
+95.15%
-5.94
Change In Account Payable
-0.94
-201.40%
0.93
+421.88%
-0.29
+95.15%
-5.94
Change In Other Working Capital
—
-0.14
—
—
Change In Other Current Assets
4.31
+591.78%
-0.88
-9633.33%
-0.01
-104.64%
0.19
Change In Other Current Liabilities
0.74
+580.73%
0.11
—
—
Investing Cash Flow
23.23
+6.02%
21.91
+480.48%
-5.76
-131.99%
18.00
Cash Flow From Continuing Investing Activities
23.23
+6.02%
21.91
+480.48%
-5.76
-131.99%
18.00
Net PPE Purchase And Sale
-0.35
-36.96%
-0.26
-60.62%
-0.16
-20.30%
-0.13
Purchase Of PPE
-0.35
-36.96%
-0.26
-60.62%
-0.16
-20.30%
-0.13
Capital Expenditure
-0.35
-36.96%
-0.26
-60.62%
-0.16
-20.30%
-0.13
Net Investment Purchase And Sale
23.58
+6.38%
22.16
+961.78%
-2.57
-134.42%
7.47
Purchase Of Investment
-34.42
+61.57%
-89.56
+21.29%
-113.78
-51.67%
-75.02
Sale Of Investment
58.00
-48.09%
111.73
+0.47%
111.21
+34.81%
82.49
Net Business Purchase And Sale
—
0.00
+100.00%
-2.12
-119.98%
10.59
Purchase Of Business
—
0.00
+100.00%
-2.12
0.00
Net Other Investing Changes
—
—
-0.91
-1400.00%
0.07
Financing Cash Flow
17.91
+475.06%
-4.78
-3439.16%
0.14
-79.77%
0.71
Cash Flow From Continuing Financing Activities
17.91
+475.06%
-4.78
-3439.16%
0.14
-79.77%
0.71
Net Issuance Payments Of Debt
—
0.00
+100.00%
-0.01
+87.76%
-0.05
Repayment Of Debt
—
0.00
+100.00%
-0.01
+87.76%
-0.05
Long Term Debt Payments
—
0.00
+100.00%
-0.01
+87.76%
-0.05
Net Long Term Debt Issuance
—
0.00
+100.00%
-0.01
+87.76%
-0.05
Net Common Stock Issuance
17.69
0.00
0.00
-100.00%
0.61
Proceeds From Stock Option Exercised
0.22
-2.22%
0.23
+51.01%
0.15
+0.68%
0.15
Net Other Financing Charges
—
-5.00
—
—
Changes In Cash
-0.29
+98.04%
-14.77
+38.21%
-23.91
+5.61%
-25.33
Effect Of Exchange Rate Changes
-0.11
-149.35%
0.23
+188.75%
0.08
-56.52%
0.18
Beginning Cash Position
6.21
-70.07%
20.75
-53.45%
44.58
-36.06%
69.72
End Cash Position
5.81
-6.49%
6.21
-70.07%
20.75
-53.45%
44.58
Free Cash Flow
-41.78
-29.90%
-32.16
-74.30%
-18.45
+58.23%
-44.17
Interest Paid Supplemental Data
0.23
0.00
—
—
Amortization Of Securities
-1.01
+56.81%
-2.35
-16.30%
-2.02
-1686.73%
-0.11
Common Stock Issuance
17.69
0.00
0.00
-100.00%
0.61
Issuance Of Capital Stock
17.69
0.00
0.00
-100.00%
0.61
Sale Of Business
—
—
0.00
-100.00%
10.59
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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