Symbols / SANA $3.69 -0.27% Sana Biotechnology, Inc.

Healthcare • Biotechnology • United States • NMS
SANA Chart
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About

Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline includes UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SG293 and SG299, a CD8-targeted fusosome for the treatment of B cell hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company has a strategic collaboration with Mayo Clinic for the development of SC451, a hypoimmune-modified pancreatic islet cell therapy for type 1 diabetes. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.

Fundamentals
Scroll to Statements
Market Cap 984.74M Enterprise Value 932.62M Income -244.17M Sales Book/sh 0.60 Cash/sh 0.52
Dividend Yield Payout 0.00% Employees 142 IPO P/E Forward P/E -6.95
PEG P/S P/B 6.12 P/C EV/EBITDA -5.23 EV/Sales
Quick Ratio 1.76 Current Ratio 1.89 Debt/Eq 53.62 LT Debt/Eq EPS (ttm) -0.96 EPS next Y -0.53
EPS Growth Revenue Growth Earnings 2026-05-07 ROA -26.00% ROE -118.70% ROIC
Gross Margin 0.00% Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 266.87M Shs Float 179.72M Short Float 40.10%
Short Ratio 13.11 Short Interest 52W High 6.55 52W Low 1.60 Beta 2.06 Avg Volume 2.86M
Volume 2.29M Target Price $8.57 Recom Strong_buy Prev Close $3.70 Price $3.69 Change -0.27%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$8.57
Mean price target
2. Current target
$3.69
Latest analyst target
3. DCF / Fair value
$-3.61
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$3.69
Low
$7.00
High
$12.00
Mean
$8.57

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-04-14 main Wedbush Outperform → Outperform $7
2026-03-04 main HC Wainwright & Co. Buy → Buy $7
2026-01-06 main B of A Securities Buy → Buy $7
2025-11-07 main Wedbush Outperform → Outperform $6
2025-11-07 main HC Wainwright & Co. Buy → Buy $9
2025-10-30 main Citizens Market Outperform → Market Outperform $8
2025-09-24 init Wedbush — → Outperform $5
2025-06-24 reit JMP Securities Market Outperform → Market Outperform $5
2025-04-24 reit HC Wainwright & Co. Buy → Buy $11
2025-03-18 up Citizens Capital Markets Market Perform → Market Outperform $5
2025-03-18 reit HC Wainwright & Co. Buy → Buy $11
2025-03-14 init Jefferies — → Buy $7
2025-01-08 main HC Wainwright & Co. Buy → Buy $11
2025-01-08 up TD Cowen Hold → Buy
2024-11-27 reit HC Wainwright & Co. Buy → Buy $8
2024-11-11 reit HC Wainwright & Co. Buy → Buy $8
2024-11-05 main HC Wainwright & Co. Buy → Buy $8
2024-11-05 down JMP Securities Market Outperform → Market Perform
2024-08-09 main Citigroup Buy → Buy $15
2024-08-09 main HC Wainwright & Co. Buy → Buy $11
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-04-06 BISHOP HANS EDGAR Director 7,763 $0.00 $0
2026-03-06 WYRICK SUSAN D Officer 13,666
2026-03-06 HARR STEVEN D Chief Executive Officer 91,666
2026-03-02 WYRICK SUSAN D Officer 1,525
2026-01-05 BISHOP HANS EDGAR Director 6,157 $0.00 $0
2026-01-02 WYRICK SUSAN D Chief Financial Officer 7,500
2025-12-12 WYRICK SUSAN D Chief Financial Officer 3,400
2025-12-03 WYRICK SUSAN D Chief Financial Officer 20,000
2025-10-06 BISHOP HANS EDGAR Director 5,628 $0.00 $0
2025-07-07 BISHOP HANS EDGAR Director 7,842 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
205.71
-24.05%
270.83
-5.35%
286.13
+4.98%
272.56
Research And Development
161.41
-21.94%
206.79
-2.84%
212.83
+5.88%
201.00
Selling General And Administration
44.30
-30.83%
64.04
-12.63%
73.30
+2.43%
71.56
General And Administrative Expense
44.30
-30.83%
64.04
-12.63%
73.30
+2.43%
71.56
Other Gand A
44.30
-30.83%
64.04
-12.63%
73.30
+2.43%
71.56
Total Expenses
205.71
-24.05%
270.83
-5.35%
286.13
+4.98%
272.56
Operating Income
-205.71
+24.05%
-270.83
+5.35%
-286.13
-4.98%
-272.56
Total Operating Income As Reported
-250.32
+8.21%
-272.72
+6.97%
-293.14
-7.55%
-272.56
EBITDA
-192.96
+24.43%
-255.33
+4.93%
-268.58
-4.53%
-256.94
Normalized EBITDA
-148.35
+41.47%
-253.44
+3.11%
-261.57
-1.80%
-256.94
Reconciled Depreciation
12.75
-17.74%
15.50
-11.65%
17.54
+12.28%
15.62
EBIT
-205.71
+24.05%
-270.83
+5.35%
-286.13
-4.98%
-272.56
Total Unusual Items
-44.61
-2259.12%
-1.89
+73.04%
-7.01
Total Unusual Items Excluding Goodwill
-44.61
-2259.12%
-1.89
+73.04%
-7.01
Special Income Charges
-44.61
-2259.12%
-1.89
+73.04%
-7.01
Impairment Of Capital Assets
44.61
+2259.12%
1.89
-73.04%
7.01
Net Income
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Pretax Income
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Net Non Operating Interest Income Expense
3.85
-63.25%
10.47
+5.36%
9.94
+164.17%
3.76
Net Interest Income
3.85
-63.25%
10.47
+5.36%
9.94
+164.17%
3.76
Interest Income Non Operating
3.85
-63.25%
10.47
+5.36%
9.94
+164.17%
3.76
Interest Income
3.85
-63.25%
10.47
+5.36%
9.94
+164.17%
3.76
Other Income Expense
-42.31
-561.24%
-6.40
+9.45%
-7.07
-948.37%
-0.67
Other Non Operating Income Expenses
2.31
+151.14%
-4.51
-8567.31%
-0.05
+92.28%
-0.67
Tax Provision
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Net Income From Continuing Operation Net Minority Interest
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Net Income From Continuing And Discontinued Operation
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Net Income Continuous Operations
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Normalized Income
-199.56
+24.66%
-264.87
+4.12%
-276.24
-2.51%
-269.48
Net Income Common Stockholders
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Diluted EPS
-1.16
+20.55%
-1.46
-2.10%
-1.43
Basic EPS
-1.16
+20.55%
-1.46
-2.10%
-1.43
Basic Average Shares
230.89
+18.69%
194.54
+3.29%
188.34
Diluted Average Shares
230.89
+18.69%
194.54
+3.29%
188.34
Diluted NI Availto Com Stockholders
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
416.89
-16.79%
501.02
-11.37%
565.30
-31.29%
822.72
Current Assets
148.68
-7.54%
160.81
-24.69%
213.51
-51.96%
444.44
Cash Cash Equivalents And Short Term Investments
138.38
-9.26%
152.50
-25.68%
205.19
-51.60%
423.96
Cash And Cash Equivalents
71.87
-43.66%
127.57
-4.46%
133.52
-24.47%
176.76
Other Short Term Investments
66.51
+166.78%
24.93
-65.22%
71.68
-71.00%
247.20
Prepaid Assets
Restricted Cash
4.20
+9.47%
3.83
+0.00%
3.83
-37.18%
6.10
Other Current Assets
6.10
+36.17%
4.48
-0.20%
4.49
-68.78%
14.37
Total Non Current Assets
268.21
-21.16%
340.21
-3.29%
351.78
-7.01%
378.28
Net PPE
65.22
-51.79%
135.27
-7.09%
145.59
-8.66%
159.40
Gross PPE
119.97
-36.67%
189.44
+1.11%
187.36
-3.11%
193.38
Accumulated Depreciation
-54.76
-1.09%
-54.17
-29.67%
-41.77
-22.94%
-33.98
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
4.14
-14.43%
4.84
+54.80%
3.12
+7.21%
2.91
Construction In Progress
0.00
-100.00%
40.34
+53.19%
26.33
+1438.98%
1.71
Other Properties
76.78
-30.78%
110.92
-12.35%
126.55
-18.00%
154.33
Leases
39.06
+17.15%
33.34
+6.32%
31.36
-8.91%
34.43
Goodwill And Other Intangible Assets
199.82
+0.00%
199.82
+0.00%
199.82
+0.00%
199.82
Goodwill
140.63
+0.00%
140.63
+0.00%
140.63
+0.00%
140.63
Other Intangible Assets
59.20
+0.00%
59.20
+0.00%
59.20
+0.00%
59.20
Investments And Advances
0.00
-100.00%
10.05
Other Non Current Assets
3.17
-38.04%
5.12
-19.61%
6.37
-29.28%
9.01
Total Liabilities Net Minority Interest
256.01
+2.19%
250.52
-9.82%
277.79
-14.10%
323.40
Current Liabilities
78.73
+73.28%
45.43
-29.55%
64.49
-42.17%
111.50
Payables And Accrued Expenses
11.86
-44.76%
21.47
-31.85%
31.51
+39.92%
22.52
Payables
1.67
-67.97%
5.21
+26.83%
4.11
+43.79%
2.86
Accounts Payable
1.67
-67.97%
5.21
+26.83%
4.11
+43.79%
2.86
Current Accrued Expenses
10.19
-37.33%
16.26
-40.65%
27.40
+39.36%
19.66
Pensionand Other Post Retirement Benefit Plans Current
11.73
+2.63%
11.43
-42.24%
19.79
-6.89%
21.25
Current Debt And Capital Lease Obligation
14.94
+19.18%
12.53
-5.01%
13.20
+6.47%
12.39
Current Capital Lease Obligation
14.94
+19.18%
12.53
-5.01%
13.20
+6.47%
12.39
Other Current Liabilities
40.20
55.34
Total Non Current Liabilities Net Minority Interest
177.28
-13.56%
205.08
-3.86%
213.31
+0.66%
211.90
Long Term Debt And Capital Lease Obligation
63.92
-21.72%
81.66
-10.16%
90.90
-5.17%
95.86
Long Term Capital Lease Obligation
63.92
-21.72%
81.66
-10.16%
90.90
-5.17%
95.86
Other Non Current Liabilities
113.36
-8.15%
123.42
+0.83%
122.41
+5.48%
116.04
Stockholders Equity
160.88
-35.78%
250.50
-12.87%
287.51
-42.42%
499.31
Common Stock Equity
160.88
-35.78%
250.50
-12.87%
287.51
-42.42%
499.31
Capital Stock
0.03
+22.73%
0.02
+10.00%
0.02
+5.26%
0.02
Common Stock
0.03
+22.73%
0.02
+10.00%
0.02
+5.26%
0.02
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
266.73
+19.12%
223.92
+13.17%
197.86
+3.58%
191.02
Ordinary Shares Number
266.73
+19.12%
223.92
+13.17%
197.86
+3.58%
191.02
Additional Paid In Capital
2,009.85
+8.33%
1,855.32
+14.13%
1,625.64
+4.31%
1,558.46
Retained Earnings
-1,849.02
-15.21%
-1,604.85
-19.94%
-1,338.09
-26.85%
-1,054.84
Gains Losses Not Affecting Retained Earnings
0.03
+100.00%
0.01
+123.33%
-0.06
+98.61%
-4.33
Other Equity Adjustments
0.03
+100.00%
0.01
+123.33%
-0.06
+98.61%
-4.33
Total Equity Gross Minority Interest
160.88
-35.78%
250.50
-12.87%
287.51
-42.42%
499.31
Total Capitalization
160.88
-35.78%
250.50
-12.87%
287.51
-42.42%
499.31
Working Capital
69.95
-39.37%
115.38
-22.58%
149.03
-55.24%
332.93
Invested Capital
160.88
-35.78%
250.50
-12.87%
287.51
-42.42%
499.31
Total Debt
78.86
-16.28%
94.20
-9.51%
104.10
-3.84%
108.25
Capital Lease Obligations
78.86
-16.28%
94.20
-9.51%
104.10
-3.84%
108.25
Net Tangible Assets
-38.94
-176.83%
50.68
-42.20%
87.68
-70.72%
299.49
Tangible Book Value
-38.94
-176.83%
50.68
-42.20%
87.68
-70.72%
299.49
Available For Sale Securities
10.05
Investmentin Financial Assets
0.00
-100.00%
10.05
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-143.83
+35.55%
-223.15
+12.00%
-253.58
+12.57%
-290.05
Cash Flow From Continuing Operating Activities
-143.83
+35.55%
-223.15
+12.00%
-253.58
+12.57%
-290.05
Net Income From Continuing Operations
-244.17
+8.47%
-266.76
+5.82%
-283.25
-5.11%
-269.48
Depreciation Amortization Depletion
12.75
-17.74%
15.50
-11.65%
17.54
+12.28%
15.62
Depreciation
12.75
-17.74%
15.50
-11.65%
17.54
+12.28%
15.62
Depreciation And Amortization
12.75
-17.74%
15.50
-11.65%
17.54
+12.28%
15.62
Other Non Cash Items
27.63
+368.80%
-10.28
+79.04%
-49.03
+40.27%
-82.08
Stock Based Compensation
25.46
-32.42%
37.68
+6.04%
35.53
-7.31%
38.34
Asset Impairment Charge
44.61
+2259.12%
1.89
-73.04%
7.01
Deferred Tax
Deferred Income Tax
Change In Working Capital
-10.11
-753.50%
-1.19
-106.37%
18.61
+146.76%
7.54
Change In Prepaid Assets
1.17
+133.16%
-3.51
-143.14%
8.14
+235.99%
-5.99
Change In Payables And Accrued Expense
-8.28
-18.09%
-7.01
-1328.31%
-0.49
-104.10%
11.97
Change In Accrued Expense
-4.74
+43.54%
-8.39
-452.70%
-1.52
-113.91%
10.91
Change In Payable
-3.54
-357.44%
1.38
+34.08%
1.03
-2.93%
1.06
Change In Account Payable
-3.54
-357.44%
1.38
+34.08%
1.03
-2.93%
1.06
Change In Other Working Capital
-3.00
-132.08%
9.34
-14.76%
10.96
+601.60%
1.56
Investing Cash Flow
-40.24
-330.55%
17.45
-89.85%
172.01
-18.31%
210.56
Cash Flow From Continuing Investing Activities
-40.24
-330.55%
17.45
-89.85%
172.01
-18.31%
210.56
Net PPE Purchase And Sale
-0.94
+97.19%
-33.43
-66.88%
-20.03
+4.04%
-20.88
Purchase Of PPE
-0.94
+97.19%
-33.43
-66.88%
-20.03
+4.04%
-20.88
Capital Expenditure
-0.94
+97.19%
-33.43
-66.88%
-20.03
+4.04%
-20.88
Net Investment Purchase And Sale
-40.73
-180.05%
50.88
-73.50%
192.04
-17.02%
231.44
Purchase Of Investment
-87.29
+61.39%
-226.06
-43.31%
-157.74
-100.47%
-78.69
Sale Of Investment
46.56
-83.19%
276.95
-20.82%
349.79
+12.79%
310.13
Net Business Purchase And Sale
Purchase Of Business
Net Other Investing Changes
1.43
Financing Cash Flow
128.73
-35.55%
199.75
+531.20%
31.65
+544.13%
4.91
Cash Flow From Continuing Financing Activities
128.73
-35.55%
199.75
+531.20%
31.65
+544.13%
4.91
Net Issuance Payments Of Debt
126.06
-33.21%
188.74
+598.53%
27.02
0.00
Issuance Of Debt
126.40
-33.03%
188.74
+598.53%
27.02
0.00
Repayment Of Debt
-0.35
Long Term Debt Issuance
126.40
-33.03%
188.74
+598.53%
27.02
0.00
Long Term Debt Payments
-0.35
Net Long Term Debt Issuance
126.06
-33.21%
188.74
+598.53%
27.02
0.00
Net Common Stock Issuance
181.00
+471.95%
31.65
+5165.56%
0.60
Proceeds From Stock Option Exercised
2.68
-75.68%
11.01
+137.89%
4.63
+7.28%
4.31
Changes In Cash
-55.33
-829.81%
-5.95
+88.08%
-49.92
+33.06%
-74.58
Beginning Cash Position
131.40
-4.33%
137.35
-26.66%
187.27
-28.48%
261.85
End Cash Position
76.06
-42.11%
131.40
-4.33%
137.35
-26.66%
187.27
Free Cash Flow
-144.77
+43.58%
-256.58
+6.22%
-273.61
+12.00%
-310.93
Common Stock Issuance
181.00
+471.95%
31.65
+5165.56%
0.60
Issuance Of Capital Stock
181.00
+471.95%
31.65
+5165.56%
0.60
Net Preferred Stock Issuance
0.00
Preferred Stock Issuance
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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