Symbols / TECX Stock $28.44 -0.21% Tectonic Therapeutic, Inc.

Healthcare • Biotechnology • United States • NGM
TECX (Stock) Chart
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About

Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines. The company's lead product is TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone, and relaxin. It is also developing TX2100 for the treatment of hereditary hemorrhagic telangiectasia; GPCR modulator bispecific for treating fibrosis; and other GPCR modulators. The company is headquartered in Watertown, Massachusetts.

Stock Fundamentals
Scroll to Statements
Market Cap 534.01M Enterprise Value 282.61M Income -74.15M Sales — Book/sh 13.41 Cash/sh 13.52
Dividend Yield — Payout 0.00% Employees 60 IPO — P/E — Forward P/E -6.08
PEG — P/S — P/B 2.12 P/C — EV/EBITDA -3.42 EV/Sales —
Quick Ratio 26.26 Current Ratio 26.62 Debt/Eq 0.51 LT Debt/Eq — EPS (ttm) -4.05 EPS next Y -4.68
EPS Growth — Revenue Growth — Earnings 2026-05-07 ROA -25.38% ROE -37.82% ROIC —
Gross Margin 0.00% Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 18.78M Shs Float 11.18M Short Float 22.56%
Short Ratio 7.54 Short Interest — 52W High 36.03 52W Low 14.39 Beta — Avg Volume 370.54K
Volume 323.12K Target Price $77.89 Recom Strong_buy Prev Close $28.50 Price $28.44 Change -0.21%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$77.89
Mean price target
2. Current target
$28.44
Latest analyst target
3. DCF / Fair value
$-37.61
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$28.44
Low
$60.00
High
$101.00
Mean
$77.89

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-04-14 init Stifel — → Buy $75
2026-01-08 main Truist Securities Buy → Buy $60
2025-09-03 init Oppenheimer — → Outperform $80
2025-07-21 init Truist Securities — → Buy $64
2025-06-06 init LifeSci Capital — → Outperform $87
2025-05-15 main Mizuho Outperform → Outperform $85
2025-04-21 init Mizuho — → Outperform $51
2025-03-21 main Wells Fargo Overweight → Overweight $101
2025-01-31 main Wells Fargo Overweight → Overweight $112
2024-11-20 init Raymond James — → Outperform $65
2024-11-12 main Wells Fargo Overweight → Overweight $79
2024-11-11 main Leerink Partners Outperform → Outperform $69
2024-08-22 init Wells Fargo — → Overweight $55
2024-07-24 init Leerink Partners — → Outperform $49
2024-06-26 init Piper Sandler — → Overweight $76
2024-06-24 init TD Cowen — → Buy —
News
RSS: Latest TECX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-04-01 RUDDY MARCELLA KUHLMAN M.D. Officer — 1,000 $31.05 $31,050
2026-03-06 MCNAMARA PETER Officer — 6,262 $30.00 $188,935
2026-03-06 MCNAMARA PETER Officer — 2,715 $2.38 $9,113
2026-03-06 RUDDY MARCELLA KUHLMAN M.D. Officer — 10,000 $30.00 $300,000
2026-03-04 REICIN ALISE S Chief Executive Officer — 76,500 $0.00 $0
2026-03-04 LOCHNER DANIEL J. Chief Financial Officer — 26,500 $0.00 $0
2026-03-04 MCNAMARA PETER Officer — 23,000 $0.00 $0
2026-03-04 MCNAMARA PETER Officer — 3,299 $22.06 $77,627
2026-03-04 SCHWABISH MARC PH.D. Officer — 19,500 $0.00 $0
2026-03-04 RUDDY MARCELLA KUHLMAN M.D. Officer — 26,500 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
84.04
+44.85%
58.02
+29.94%
44.65
+36.00%
32.83
Research And Development
63.49
+53.49%
41.36
+11.90%
36.97
+44.09%
25.65
Selling General And Administration
20.55
+23.40%
16.65
+116.75%
7.68
+7.05%
7.18
General And Administrative Expense
20.55
+23.40%
16.65
+116.75%
7.68
+7.05%
7.18
Salaries And Wages
11.55
+46.91%
7.86
+99.34%
3.94
+0.18%
3.94
Other Gand A
9.00
+2.37%
8.79
+135.13%
3.74
+15.41%
3.24
Total Expenses
84.04
+44.85%
58.02
+29.94%
44.65
+36.00%
32.83
Operating Income
-84.04
-44.85%
-58.02
-29.94%
-44.65
-36.00%
-32.83
Total Operating Income As Reported
-84.04
-44.85%
-58.02
-29.94%
-44.65
-36.00%
-32.83
EBITDA
-71.48
-27.13%
-56.23
-36.50%
-41.19
-32.75%
-31.03
Normalized EBITDA
-71.48
-35.85%
-52.62
-23.96%
-42.45
-34.02%
-31.67
Reconciled Depreciation
1.38
-16.41%
1.65
+11.30%
1.48
+46.92%
1.01
EBIT
-72.86
-25.89%
-57.88
-35.63%
-42.67
-33.20%
-32.04
Total Unusual Items
—
-3.61
-387.65%
1.25
+95.18%
0.64
Total Unusual Items Excluding Goodwill
—
-3.61
-387.65%
1.25
+95.18%
0.64
Net Income
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Pretax Income
-72.92
-25.76%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Net Non Operating Interest Income Expense
11.23
+170.44%
4.15
+868.30%
0.43
+8480.00%
0.01
Interest Expense Non Operating
0.06
-41.12%
0.11
-29.61%
0.15
+5.56%
0.14
Net Interest Income
11.23
+170.44%
4.15
+868.30%
0.43
+8480.00%
0.01
Interest Expense
0.06
-41.12%
0.11
-29.61%
0.15
+5.56%
0.14
Interest Income Non Operating
11.30
+165.13%
4.26
+633.39%
0.58
+289.93%
0.15
Interest Income
11.30
+165.13%
4.26
+633.39%
0.58
+289.93%
0.15
Other Income Expense
-0.12
+97.11%
-4.12
-395.20%
1.40
+116.43%
0.65
Other Non Operating Income Expenses
-0.12
+76.71%
-0.51
-462.41%
0.14
+6950.00%
0.00
Gain On Sale Of Security
—
-3.61
-387.65%
1.25
+95.18%
0.64
Tax Provision
1.23
0.00
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Net Income From Continuing Operation Net Minority Interest
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Net Income From Continuing And Discontinued Operation
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Net Income Continuous Operations
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Normalized Income
-74.15
-36.38%
-54.37
-23.35%
-44.08
-34.29%
-32.82
Net Income Common Stockholders
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Diluted EPS
—
-6.83
-135.00%
-2.91
-33.07%
-2.18
Basic EPS
—
-6.83
-135.00%
-2.91
-33.07%
-2.18
Basic Average Shares
—
8.49
-42.38%
14.73
+0.00%
14.73
Diluted Average Shares
—
8.49
-42.38%
14.73
+0.00%
14.73
Diluted NI Availto Com Stockholders
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
261.04
+70.72%
152.91
+288.09%
39.40
-16.54%
47.21
Current Assets
257.36
+75.24%
146.86
+375.51%
30.88
-16.62%
37.04
Cash Cash Equivalents And Short Term Investments
253.80
+79.69%
141.24
+390.94%
28.77
-20.01%
35.97
Cash And Cash Equivalents
253.80
+79.69%
141.24
+390.94%
28.77
-20.01%
35.97
Restricted Cash
0.59
0.00
—
—
Other Current Assets
2.97
-47.06%
5.62
+165.63%
2.12
+96.56%
1.08
Total Non Current Assets
3.68
-39.17%
6.05
-28.97%
8.52
-16.25%
10.17
Net PPE
2.55
-51.86%
5.30
-26.60%
7.23
-24.35%
9.55
Gross PPE
5.96
-25.95%
8.05
-11.38%
9.08
-12.91%
10.43
Accumulated Depreciation
-3.41
-24.12%
-2.75
-47.90%
-1.86
-111.63%
-0.88
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
0.28
+0.00%
0.28
-30.62%
0.41
+3.05%
0.39
Construction In Progress
—
0.00
-100.00%
0.04
-22.45%
0.05
Other Properties
5.66
-26.98%
7.74
-10.12%
8.62
-13.53%
9.96
Leases
0.03
+0.00%
0.03
+0.00%
0.03
+0.00%
0.03
Non Current Deferred Assets
—
0.00
-100.00%
0.67
—
Other Non Current Assets
1.12
+51.41%
0.74
+20.23%
0.62
+0.82%
0.61
Total Liabilities Net Minority Interest
9.71
-19.95%
12.13
-90.22%
124.03
+33.57%
92.86
Current Liabilities
9.67
-16.74%
11.61
-71.61%
40.89
+421.73%
7.84
Payables And Accrued Expenses
4.32
-17.52%
5.24
-7.96%
5.69
+52.61%
3.73
Payables
1.09
+11.99%
0.98
+138.63%
0.41
-28.75%
0.57
Accounts Payable
1.09
+11.99%
0.98
+138.63%
0.41
-28.75%
0.57
Current Accrued Expenses
3.23
-24.27%
4.26
-19.30%
5.29
+67.41%
3.16
Pensionand Other Post Retirement Benefit Plans Current
4.11
+14.64%
3.58
+25.53%
2.86
+32.34%
2.16
Current Debt And Capital Lease Obligation
1.23
-55.71%
2.78
+52.72%
1.82
+25.81%
1.45
Current Capital Lease Obligation
1.23
-55.71%
2.78
+52.72%
1.82
+25.81%
1.45
Current Deferred Liabilities
—
—
—
0.00
Other Current Liabilities
—
—
30.52
+6015.23%
0.50
Total Non Current Liabilities Net Minority Interest
0.04
-91.71%
0.52
-99.38%
83.15
-2.21%
85.03
Long Term Debt And Capital Lease Obligation
0.04
-91.71%
0.52
-79.40%
2.52
-41.98%
4.34
Long Term Capital Lease Obligation
0.04
-91.71%
0.52
-79.40%
2.52
-41.98%
4.34
Non Current Deferred Liabilities
—
—
—
0.00
Other Non Current Liabilities
—
—
—
0.06
Preferred Securities Outside Stock Equity
—
0.00
-100.00%
80.63
+0.00%
80.63
Stockholders Equity
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Common Stock Equity
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Capital Stock
0.00
+0.00%
0.00
0.00
0.00
Common Stock
0.00
+0.00%
0.00
0.00
0.00
Preferred Stock
0.00
0.00
0.00
—
Share Issued
18.74
+26.13%
14.86
+0.83%
14.73
+0.00%
14.73
Ordinary Shares Number
18.74
+26.13%
14.86
+0.83%
14.73
+0.00%
14.73
Additional Paid In Capital
474.16
+63.87%
289.35
+4739.45%
5.98
+181.10%
2.13
Retained Earnings
-222.74
-49.90%
-148.59
-63.99%
-90.60
-89.62%
-47.78
Gains Losses Not Affecting Retained Earnings
-0.10
-1166.67%
0.01
+181.82%
-0.01
—
Other Equity Adjustments
-0.10
-1166.67%
0.01
+181.82%
-0.01
—
Total Equity Gross Minority Interest
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Total Capitalization
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Working Capital
247.69
+83.14%
135.25
+1451.93%
-10.00
-134.25%
29.20
Invested Capital
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Total Debt
1.28
-61.37%
3.30
-23.95%
4.34
-25.02%
5.79
Capital Lease Obligations
1.28
-61.37%
3.30
-23.95%
4.34
-25.02%
5.79
Net Tangible Assets
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Tangible Book Value
251.33
+78.53%
140.78
+266.33%
-84.64
-85.39%
-45.65
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-60.08
-1.69%
-59.08
-45.23%
-40.68
-47.20%
-27.64
Cash Flow From Continuing Operating Activities
-60.08
-1.69%
-59.08
-45.23%
-40.68
-47.20%
-27.64
Net Income From Continuing Operations
-74.15
-27.89%
-57.98
-35.40%
-42.82
-33.07%
-32.18
Depreciation Amortization Depletion
1.38
-16.41%
1.65
+11.30%
1.48
+46.92%
1.01
Depreciation And Amortization
1.38
-16.41%
1.65
+11.30%
1.48
+46.92%
1.01
Other Non Cash Items
2.12
-47.63%
4.04
+3051.82%
-0.14
-111.18%
1.23
Stock Based Compensation
10.50
+200.69%
3.49
+211.42%
1.12
+0.18%
1.12
Operating Gains Losses
0.15
—
0.26
+141.06%
-0.64
Gain Loss On Investment Securities
—
—
—
-0.64
Gain Loss On Sale Of PPE
0.15
0.00
-100.00%
0.01
—
Change In Working Capital
-0.07
+99.32%
-10.28
-1659.93%
-0.58
-131.81%
1.84
Change In Prepaid Assets
2.64
+182.78%
-3.19
-213.44%
-1.02
-171.01%
-0.38
Change In Payables And Accrued Expense
-0.44
+93.83%
-7.06
-588.45%
1.45
-55.85%
3.27
Change In Accrued Expense
-0.55
+90.22%
-5.64
-450.22%
1.61
-64.27%
4.51
Change In Payable
0.12
+108.16%
-1.42
-761.21%
-0.17
+86.63%
-1.23
Change In Account Payable
0.12
+108.16%
-1.42
-761.21%
-0.17
+86.63%
-1.23
Change In Other Current Assets
0.02
-96.88%
0.54
+10980.00%
-0.01
+64.29%
-0.01
Change In Other Current Liabilities
-2.29
-306.19%
-0.56
+43.84%
-1.01
+4.10%
-1.05
Investing Cash Flow
-0.14
+11.54%
-0.16
+44.09%
-0.28
+86.64%
-2.09
Cash Flow From Continuing Investing Activities
-0.14
+11.54%
-0.16
+44.09%
-0.28
+86.64%
-2.09
Net PPE Purchase And Sale
-0.14
+11.54%
-0.16
+44.09%
-0.28
+86.64%
-2.09
Purchase Of PPE
-0.21
-33.33%
-0.16
+44.09%
-0.28
+86.64%
-2.09
Sale Of PPE
0.07
0.00
—
—
Capital Expenditure
-0.21
-33.33%
-0.16
+44.09%
-0.28
+86.64%
-2.09
Gain Loss On Sale Of Business
—
0.00
-100.00%
0.26
—
Financing Cash Flow
173.35
+0.96%
171.71
+408.83%
33.75
-10.31%
37.63
Cash Flow From Continuing Financing Activities
173.35
+0.96%
171.71
+408.83%
33.75
-10.31%
37.63
Net Issuance Payments Of Debt
-0.49
-2.95%
-0.47
+4.81%
-0.50
-26.97%
-0.39
Issuance Of Debt
—
—
—
0.00
Repayment Of Debt
-0.49
-2.95%
-0.47
+4.81%
-0.50
-26.97%
-0.39
Long Term Debt Issuance
—
—
—
0.00
Long Term Debt Payments
-0.49
-2.95%
-0.47
+4.81%
-0.50
-26.97%
-0.39
Net Long Term Debt Issuance
-0.49
-2.95%
-0.47
+4.81%
-0.50
-26.97%
-0.39
Net Common Stock Issuance
173.10
+82.98%
94.60
+177.22%
34.12
—
Proceeds From Stock Option Exercised
1.23
-24.20%
1.62
+1242.15%
0.12
+2925.00%
0.00
Net Other Financing Charges
-0.48
-100.64%
75.97
—
—
Changes In Cash
113.14
+0.59%
112.48
+1659.38%
-7.21
-191.27%
7.90
Effect Of Exchange Rate Changes
-0.10
-1087.50%
-0.01
-150.00%
0.02
—
Beginning Cash Position
141.83
+383.12%
29.36
-19.69%
36.55
+27.58%
28.65
End Cash Position
254.87
+79.71%
141.83
+383.12%
29.36
-19.69%
36.55
Free Cash Flow
-60.29
-1.77%
-59.24
-44.62%
-40.96
-37.80%
-29.73
Interest Paid Supplemental Data
0.06
-41.12%
0.11
-29.61%
0.15
+5.56%
0.14
Common Stock Issuance
173.10
+82.98%
94.60
+177.22%
34.12
—
Issuance Of Capital Stock
173.10
+82.98%
94.60
+177.22%
34.12
-10.24%
38.02
Net Preferred Stock Issuance
—
—
—
38.02
Preferred Stock Issuance
—
—
—
38.02
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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