Symbols / TNYA $0.74 +6.22% Tenaya Therapeutics, Inc.

Healthcare • Biotechnology • United States • NMS
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About

Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.

Fundamentals
Scroll to Statements
Market Cap 159.73M Enterprise Value 70.02M Income -90.60M Sales — Book/sh 0.57 Cash/sh 0.46
Dividend Yield — Payout 0.00% Employees 70 IPO — P/E — Forward P/E -1.63
PEG — P/S — P/B 1.29 P/C — EV/EBITDA -0.82 EV/Sales —
Quick Ratio 6.51 Current Ratio 6.84 Debt/Eq 8.79 LT Debt/Eq — EPS (ttm) -0.59 EPS next Y -0.45
EPS Growth — Revenue Growth — Earnings 2026-05-13 ROA -43.72% ROE -83.84% ROIC —
Gross Margin 0.00% Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 217.00M Shs Float 166.77M Short Float 22.22%
Short Ratio 4.50 Short Interest — 52W High 2.35 52W Low 0.36 Beta 3.00 Avg Volume 4.42M
Volume 2.91M Target Price $9.00 Recom Strong_buy Prev Close $0.69 Price $0.74 Change 6.22%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$9.00
Mean price target
2. Current target
$0.74
Latest analyst target
3. DCF / Fair value
$-3.10
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$0.74
Low
$2.00
High
$40.00
Mean
$9.00

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-12 main Chardan Capital Buy → Buy $8
2025-12-18 main Canaccord Genuity Buy → Buy $5
2025-12-12 main HC Wainwright & Co. Buy → Buy $3
2025-12-12 main Chardan Capital Buy → Buy $8
2025-11-10 main Chardan Capital Buy → Buy $9
2025-09-02 reit HC Wainwright & Co. Buy → Buy $5
2025-08-27 reit HC Wainwright & Co. Buy → Buy $5
2025-08-07 main Chardan Capital Buy → Buy $9
2025-05-09 main Chardan Capital Buy → Buy $9
2025-04-25 reit HC Wainwright & Co. Buy → Buy $5
2025-03-31 reit HC Wainwright & Co. Buy → Buy $5
2025-03-13 main Canaccord Genuity Buy → Buy $6
2025-03-12 main Morgan Stanley Overweight → Overweight $5
2025-03-12 main Chardan Capital Buy → Buy $9
2025-03-11 main HC Wainwright & Co. Buy → Buy $5
2025-02-03 reit HC Wainwright & Co. Buy → Buy $18
2025-01-14 reit HC Wainwright & Co. Buy → Buy $18
2024-12-18 main Chardan Capital Buy → Buy $18
2024-12-18 reit HC Wainwright & Co. Buy → Buy $18
2024-11-26 reit HC Wainwright & Co. Buy → Buy $18
News
RSS: Latest TNYA news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-02-25 COLUMN GROUP III GP, L.P Beneficial Owner of more than 10% of a Class of Security — 4,170,266 $0.56 $2,380,189
2026-02-23 COLUMN GROUP III GP, L.P Beneficial Owner of more than 10% of a Class of Security — 829,734 $0.60 $504,787
2026-02-17 ALI FARAZ Chief Executive Officer — 14,862 $0.64 $9,557
2026-02-17 TINGLEY WHITTEMORE PH.D., M.D. Officer — 5,160 $0.64 $3,319
2026-02-17 HIGA TOMOHIRO Officer — 3,469 $0.64 $2,231
2026-02-11 COLUMN GROUP III GP, L.P Beneficial Owner of more than 10% of a Class of Security — 4,400,290 $0.68 $3,042,222
2026-02-03 ALI FARAZ Chief Executive Officer — 158,600 $0.00 $0
2026-02-03 TINGLEY WHITTEMORE PH.D., M.D. Officer — 48,750 $0.00 $0
2026-02-03 HIGA TOMOHIRO Officer — 29,250 $0.00 $0
2025-11-17 ALI FARAZ Chief Executive Officer — 3,126 $1.33 $4,158
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
93.33
-19.51%
115.95
-11.62%
131.19
+4.44%
125.62
Research And Development
68.61
-20.91%
86.74
-11.52%
98.04
+3.70%
94.54
Selling General And Administration
24.72
-15.35%
29.21
-11.91%
33.16
+6.66%
31.08
General And Administrative Expense
24.72
-15.35%
29.21
-11.91%
33.16
+6.66%
31.08
Other Gand A
24.72
-15.35%
29.21
-11.91%
33.16
+6.66%
31.08
Total Expenses
93.33
-19.51%
115.95
-11.62%
131.19
+4.44%
125.62
Operating Income
-93.33
+19.51%
-115.95
+11.62%
-131.19
-4.44%
-125.62
Total Operating Income As Reported
-93.33
+19.51%
-115.95
+11.62%
-131.19
-4.44%
-125.62
EBITDA
-84.89
+21.01%
-107.48
+12.27%
-122.51
-2.81%
-119.15
Normalized EBITDA
-84.89
+21.01%
-107.48
+12.27%
-122.51
-2.81%
-119.15
Reconciled Depreciation
8.44
-0.38%
8.47
-2.52%
8.69
+34.33%
6.47
EBIT
-93.33
+19.51%
-115.95
+11.62%
-131.19
-4.44%
-125.62
Net Income
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Pretax Income
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Net Non Operating Interest Income Expense
2.68
-43.38%
4.74
-32.87%
7.06
+261.11%
1.95
Net Interest Income
2.68
-43.38%
4.74
-32.87%
7.06
+261.11%
1.95
Interest Income Non Operating
2.68
-43.38%
4.74
-32.87%
7.06
+261.11%
1.95
Interest Income
2.68
-43.38%
4.74
-32.87%
7.06
+261.11%
1.95
Other Income Expense
0.05
-36.59%
0.08
+54.72%
0.05
+2550.00%
0.00
Other Non Operating Income Expenses
0.05
-36.59%
0.08
+54.72%
0.05
+2550.00%
0.00
Tax Provision
0.00
0.00
0.00
0.00
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Net Income From Continuing Operation Net Minority Interest
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Net Income From Continuing And Discontinued Operation
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Net Income Continuous Operations
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Normalized Income
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Net Income Common Stockholders
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Diluted EPS
—
-1.31
+22.02%
-1.68
+39.13%
-2.76
Basic EPS
—
-1.31
+22.02%
-1.68
+39.13%
-2.76
Basic Average Shares
—
84.82
+14.96%
73.79
+64.61%
44.82
Diluted Average Shares
—
84.82
+14.96%
73.79
+64.61%
44.82
Diluted NI Availto Com Stockholders
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Line Item Trend 2023-12-31
Total Assets
170.51
Current Assets
111.58
Cash Cash Equivalents And Short Term Investments
104.64
Cash And Cash Equivalents
45.68
Other Short Term Investments
58.96
Receivables
0.00
Taxes Receivable
0.00
Prepaid Assets
5.78
Other Current Assets
1.16
Total Non Current Assets
58.93
Net PPE
53.26
Gross PPE
77.60
Accumulated Depreciation
-24.34
Properties
0.00
Machinery Furniture Equipment
20.31
Construction In Progress
1.73
Other Properties
29.95
Leases
25.61
Investments And Advances
0.00
Other Non Current Assets
5.68
Total Liabilities Net Minority Interest
31.09
Current Liabilities
22.73
Payables And Accrued Expenses
9.24
Payables
5.91
Accounts Payable
5.63
Current Accrued Expenses
3.33
Pensionand Other Post Retirement Benefit Plans Current
8.70
Total Tax Payable
0.28
Current Debt And Capital Lease Obligation
4.32
Current Capital Lease Obligation
4.32
Current Deferred Liabilities
—
Other Current Liabilities
0.48
Total Non Current Liabilities Net Minority Interest
8.36
Long Term Debt And Capital Lease Obligation
8.11
Long Term Capital Lease Obligation
8.11
Non Current Deferred Liabilities
—
Other Non Current Liabilities
0.25
Preferred Securities Outside Stock Equity
—
Stockholders Equity
139.42
Common Stock Equity
139.42
Capital Stock
0.01
Common Stock
0.01
Preferred Stock
0.00
Share Issued
68.33
Ordinary Shares Number
68.33
Treasury Shares Number
0.00
Additional Paid In Capital
542.80
Retained Earnings
-403.28
Gains Losses Not Affecting Retained Earnings
-0.11
Other Equity Adjustments
-0.11
Total Equity Gross Minority Interest
139.42
Total Capitalization
139.42
Working Capital
88.85
Invested Capital
139.42
Total Debt
12.42
Capital Lease Obligations
12.42
Net Tangible Assets
139.42
Tangible Book Value
139.42
Available For Sale Securities
—
Investmentin Financial Assets
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-68.26
+24.57%
-90.50
+11.34%
-102.07
+2.25%
-104.42
Cash Flow From Continuing Operating Activities
-68.26
+24.57%
-90.50
+11.34%
-102.07
+2.25%
-104.42
Net Income From Continuing Operations
-90.60
+18.48%
-111.13
+10.44%
-124.08
-0.34%
-123.67
Depreciation Amortization Depletion
8.44
-0.38%
8.47
-2.52%
8.69
+34.33%
6.47
Depreciation
—
8.47
-2.52%
8.69
+34.33%
6.47
Depreciation And Amortization
8.44
-0.38%
8.47
-2.52%
8.69
+34.33%
6.47
Other Non Cash Items
2.90
-23.26%
3.77
+12.69%
3.35
+35.97%
2.46
Stock Based Compensation
13.05
-20.94%
16.50
+7.79%
15.31
+33.50%
11.47
Operating Gains Losses
—
—
—
—
Gain Loss On Sale Of PPE
—
—
—
—
Change In Working Capital
-2.46
+69.03%
-7.93
-40.42%
-5.65
-565.25%
-0.85
Change In Prepaid Assets
0.55
-36.17%
0.86
+748.51%
0.10
+103.44%
-2.93
Change In Payables And Accrued Expense
-0.90
+83.14%
-5.33
-419.10%
-1.03
-117.08%
6.01
Change In Accrued Expense
0.53
+111.21%
-4.75
-310.33%
2.26
-48.11%
4.35
Change In Payable
-1.43
-146.13%
-0.58
+82.30%
-3.28
-297.71%
1.66
Change In Account Payable
-1.43
-146.13%
-0.58
+82.30%
-3.28
-297.71%
1.66
Change In Other Current Assets
0.57
-12.96%
0.66
+209.15%
-0.60
+26.26%
-0.81
Change In Other Current Liabilities
-2.68
+35.02%
-4.12
+0.10%
-4.12
-32.63%
-3.11
Investing Cash Flow
56.08
+4858.71%
1.13
-97.68%
48.72
-41.76%
83.65
Cash Flow From Continuing Investing Activities
56.08
+4858.71%
1.13
-97.68%
48.72
-41.76%
83.65
Net PPE Purchase And Sale
-0.62
+39.71%
-1.02
+17.27%
-1.24
+93.99%
-20.63
Purchase Of PPE
-0.62
+39.71%
-1.02
+17.27%
-1.24
+93.99%
-20.63
Capital Expenditure
-0.62
+39.71%
-1.02
+17.27%
-1.24
+93.99%
-20.63
Net Investment Purchase And Sale
56.70
+2550.82%
2.14
-95.72%
49.98
-52.07%
104.27
Purchase Of Investment
0.00
+100.00%
-87.07
-53.71%
-56.64
+59.68%
-140.48
Sale Of Investment
56.70
-36.44%
89.21
-16.33%
106.62
-56.44%
244.75
Net Other Investing Changes
—
0.02
+168.00%
-0.03
-412.50%
0.01
Financing Cash Flow
108.41
+127.03%
47.75
+1079.28%
4.05
-94.79%
77.77
Cash Flow From Continuing Financing Activities
108.41
+127.03%
47.75
+1079.28%
4.05
-94.79%
77.77
Net Common Stock Issuance
105.98
+126.63%
46.76
+1108.95%
3.87
-95.00%
77.39
Common Stock Payments
—
—
—
0.00
Repurchase Of Capital Stock
—
—
—
0.00
Proceeds From Stock Option Exercised
2.43
+146.00%
0.99
+44.72%
0.68
+79.47%
0.38
Net Other Financing Charges
—
—
-0.50
—
Changes In Cash
96.22
+331.19%
-41.62
+15.59%
-49.31
-186.51%
56.99
Beginning Cash Position
4.74
-89.77%
46.36
-51.54%
95.67
+147.37%
38.68
End Cash Position
100.97
+2029.19%
4.74
-89.77%
46.36
-51.54%
95.67
Free Cash Flow
-68.88
+24.74%
-91.53
+11.41%
-103.31
+17.39%
-125.05
Amortization Of Securities
0.41
+323.37%
-0.18
-158.41%
0.32
+202.61%
-0.31
Common Stock Issuance
105.98
+126.63%
46.76
+1108.95%
3.87
-95.00%
77.39
Issuance Of Capital Stock
105.98
+126.63%
46.76
+1108.95%
3.87
-95.00%
77.39
Net Preferred Stock Issuance
—
—
—
0.00
Preferred Stock Issuance
—
—
—
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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