TRVI Chart
About

Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of investigational therapy for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF) and non-IPF interstitial lung disease, and refractory chronic cough. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase 2b Cough Reduction in IPF with nalbuphine ER clinical trial for treatment of chronic cough in patients with IPF; phase 2 clinical trial in patients with pruritus; and phase 2b/3 clinical trial in patients with prurigo nodularis. Trevi Therapeutics, Inc. has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in various formulations. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 1.45B
Enterprise Value 1.25B Income -45.86M Sales —
Book/sh 1.48 Cash/sh 1.52 Dividend Yield —
Payout 0.00% Employees 34 IPO —
P/E — Forward P/E -25.21 PEG —
P/S — P/B 7.62 P/C —
EV/EBITDA -24.46 EV/Sales — Quick Ratio 21.69
Current Ratio 21.93 Debt/Eq 0.43 LT Debt/Eq —
EPS (ttm) -0.37 EPS next Y -0.45 EPS Growth —
Revenue Growth — Earnings 2026-03-17 ROA -23.93%
ROE -36.87% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 128.23M
Shs Float 103.76M Short Float 13.90% Short Ratio 10.42
Short Interest — 52W High 14.39 52W Low 4.09
Beta 0.96 Avg Volume 1.76M Volume 1.12M
Target Price $21.55 Recom Strong_buy Prev Close $11.10
Price $11.28 Change 1.62%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$21.55
Mean price target
2. Current target
$11.28
Latest analyst target
3. DCF / Fair value
$-4.05
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$11.28
Low
$16.00
High
$27.00
Mean
$21.55

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-09 reit HC Wainwright & Co. Buy → Buy $21
2026-01-08 main D. Boral Capital Buy → Buy $19
2025-12-19 main Stifel Buy → Buy $18
2025-11-20 main Leerink Partners Outperform → Outperform $16
2025-11-14 main D. Boral Capital Buy → Buy $19
2025-11-14 main Oppenheimer Outperform → Outperform $24
2025-11-14 main Morgan Stanley Overweight → Overweight $19
2025-11-14 main Clear Street Buy → Buy $21
2025-08-21 init Morgan Stanley — → Overweight $18
2025-08-08 main Raymond James Strong Buy → Strong Buy $27
2025-08-08 main Needham Buy → Buy $22
2025-07-01 init Cantor Fitzgerald — → Overweight $25
2025-06-02 main D. Boral Capital Buy → Buy $21
2025-05-28 init HC Wainwright & Co. — → Buy $21
2025-05-20 reit Needham Buy → Buy $24
2025-04-08 reit Needham Buy → Buy $24
2025-03-19 reit B. Riley Securities Buy → Buy $20
2025-03-19 main Needham Buy → Buy $24
2025-03-19 main D. Boral Capital Buy → Buy $21
2025-03-19 reit HC Wainwright & Co. Buy → Buy $13
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 4225 2159 — Conversion of Exercise of derivative security at price 0.51 per share. GALLETTA CHRISTOPHER Officer — 2025-12-02 00:00:00 D
1 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. BASKETT FOREST Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
2 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. WALKER PAUL EDWARD Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
3 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. FLORENCE ANTHONY A JR Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
4 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. BEHBAHANI ALI Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
5 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. MAKHZOUMI MOHAMAD Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
6 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. NEW ENTERPRISE ASSOCIATES 16, L.P. Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
7 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. CHANG CARMEN Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
8 1851852 2537037 — Conversion of Exercise of derivative security at price 1.37 per share. SANDELL SCOTT D Beneficial Owner of more than 10% of a Class of Security — 2025-04-17 00:00:00 I
9 2631 17365 — Sale at price 6.60 per share. SCIASCIA THOMAS R Officer — 2025-03-25 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.00-147.0082.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-47.79M-28.58M-27.84M-32.79M
TotalUnusualItems-147.00K82.00K
TotalUnusualItemsExcludingGoodwill-147.00K82.00K
NetIncomeFromContinuingOperationNetMinorityInterest-47.91M-29.07M-29.15M-33.94M
ReconciledDepreciation147.00K123.00K43.00K50.00K
EBITDA-47.79M-28.58M-27.98M-32.71M
EBIT-47.94M-28.71M-28.02M-32.76M
NetInterestIncome3.60M4.36M577.00K-1.19M
InterestExpense4.00K391.00K1.16M1.20M
InterestIncome3.60M4.75M1.74M10.00K
NormalizedIncome-47.91M-29.07M-29.01M-34.02M
NetIncomeFromContinuingAndDiscontinuedOperation-47.91M-29.07M-29.15M-33.94M
TotalExpenses51.52M33.92M29.91M32.48M
TotalOperatingIncomeAsReported-51.52M-33.92M-29.91M-32.48M
DilutedAverageShares101.97M99.03M64.54M22.84M
BasicAverageShares101.97M99.03M64.54M22.84M
DilutedEPS-0.47-0.29-0.45-1.49
BasicEPS-0.47-0.29-0.45-1.49
DilutedNIAvailtoComStockholders-47.91M-29.07M-29.15M-33.94M
NetIncomeCommonStockholders-47.91M-29.07M-29.15M-33.94M
NetIncome-47.91M-29.07M-29.15M-33.94M
NetIncomeIncludingNoncontrollingInterests-47.91M-29.07M-29.15M-33.94M
NetIncomeContinuousOperations-47.91M-29.07M-29.15M-33.94M
TaxProvision-30.00K-32.00K-36.00K-21.00K
PretaxIncome-47.94M-29.10M-29.19M-33.96M
OtherIncomeExpense-15.00K469.00K142.00K-293.00K
OtherNonOperatingIncomeExpenses-15.00K469.00K289.00K-375.00K
GainOnSaleOfSecurity-147.00K82.00K
NetNonOperatingInterestIncomeExpense3.60M4.36M577.00K-1.19M
TotalOtherFinanceCost383.00K474.00K
InterestExpenseNonOperating4.00K391.00K1.16M1.20M
InterestIncomeNonOperating3.60M4.75M1.74M10.00K
OperatingIncome-51.52M-33.92M-29.91M-32.48M
OperatingExpense51.52M33.92M29.91M32.48M
ResearchAndDevelopment39.38M23.68M19.83M22.98M
SellingGeneralAndAdministration12.15M10.24M10.07M9.49M
GeneralAndAdministrativeExpense12.15M10.24M10.07M9.49M
OtherGandA12.15M10.24M10.07M9.49M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2024-12-312023-12-312022-12-312021-12-31
OrdinarySharesNumber93.60M68.28M59.94M28.51M
ShareIssued93.60M68.28M59.94M28.51M
TotalDebt1.03M1.34M9.18M14.63M
TangibleBookValue99.64M82.55M107.46M17.07M
InvestedCapital99.64M82.55M116.61M31.56M
WorkingCapital98.92M81.72M109.22M25.23M
NetTangibleAssets99.64M82.55M107.46M17.07M
CapitalLeaseObligations1.03M1.34M27.00K144.00K
CommonStockEquity99.64M82.55M107.46M17.07M
TotalCapitalization99.64M82.55M109.61M25.73M
TotalEquityGrossMinorityInterest99.64M82.55M107.46M17.07M
StockholdersEquity99.64M82.55M107.46M17.07M
GainsLossesNotAffectingRetainedEarnings61.00K-29.00K-122.00K0.00
OtherEquityAdjustments61.00K-29.00K-122.00K
RetainedEarnings-287.05M-239.13M-210.07M-180.92M
AdditionalPaidInCapital386.53M321.64M317.59M197.96M
CapitalStock94.00K68.00K60.00K29.00K
CommonStock94.00K68.00K60.00K29.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest11.26M6.86M15.56M21.40M
TotalNonCurrentLiabilitiesNetMinorityInterest747.00K1.03M2.16M8.68M
OtherNonCurrentLiabilities3.00K
DerivativeProductLiabilities0.00
LongTermDebtAndCapitalLeaseObligation747.00K1.03M2.15M8.68M
LongTermCapitalLeaseObligation747.00K1.03M2.00K24.00K
LongTermDebt2.15M8.65M
CurrentLiabilities10.51M5.82M13.40M12.72M
OtherCurrentLiabilities114.00K
CurrentDebtAndCapitalLeaseObligation285.00K306.00K7.03M5.95M
CurrentCapitalLeaseObligation285.00K306.00K25.00K120.00K
CurrentDebt7.00M5.83M
OtherCurrentBorrowings7.00M5.83M
PensionandOtherPostRetirementBenefitPlansCurrent2.54M1.61M1.51M1.25M
PayablesAndAccruedExpenses7.69M3.90M4.87M5.41M
CurrentAccruedExpenses4.27M2.10M2.01M2.56M
Payables3.41M1.81M2.86M2.85M
AccountsPayable3.41M1.81M2.86M2.85M
TotalAssets110.90M89.40M123.02M38.48M
TotalNonCurrentAssets1.47M1.86M399.00K518.00K
OtherNonCurrentAssets243.00K297.00K205.00K334.00K
NetPPE1.23M1.56M194.00K184.00K
AccumulatedDepreciation-228.00K-134.00K-225.00K-182.00K
GrossPPE1.46M1.69M419.00K366.00K
Leases29.00K29.00K130.00K130.00K
ConstructionInProgress7.00K17.00K53.00K0.00
OtherProperties1.07M1.34M24.00K131.00K
MachineryFurnitureEquipment349.00K304.00K212.00K105.00K
Properties0.000.000.000.00
CurrentAssets109.43M87.55M122.62M37.96M
OtherCurrentAssets867.00K955.00K1.31M241.00K
PrepaidAssets939.00K3.62M795.00K886.00K
Receivables241.00K
TaxesReceivable241.00K
CashCashEquivalentsAndShortTermInvestments107.62M82.97M120.51M36.83M
OtherShortTermInvestments73.53M50.57M107.92M0.00
CashAndCashEquivalents34.10M32.40M12.59M36.83M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-38.29M-31.85M-28.33M-28.95M
RepaymentOfDebt-126.00K-9.50M-5.83M0.00
IssuanceOfDebt0.00
IssuanceOfCapitalStock61.15M1.71M105.41M21.18M
CapitalExpenditure-35.00K-137.00K-159.00K
InterestPaidSupplementalData4.00K331.00K594.00K603.00K
EndCashPosition34.10M32.40M12.59M36.83M
BeginningCashPosition32.40M12.59M36.83M45.00M
ChangesInCash1.70M19.81M-24.24M-8.17M
FinancingCashFlow61.48M-7.91M111.31M20.77M
CashFlowFromContinuingFinancingActivities61.48M-7.91M111.31M20.77M
NetOtherFinancingCharges-258.00K-247.00K-450.00K
ProceedsFromStockOptionExercised464.00K142.00K11.98M42.00K
NetCommonStockIssuance61.15M1.71M105.41M21.18M
CommonStockIssuance61.15M1.71M105.41M21.18M
NetIssuancePaymentsOfDebt-126.00K-9.50M-5.83M0.00
NetShortTermDebtIssuance0.00-9.41M
ShortTermDebtPayments0.00-9.41M
NetLongTermDebtIssuance-126.00K-9.50M-5.83M0.00
LongTermDebtPayments-126.00K-9.50M-5.83M0.00
LongTermDebtIssuance0.00
InvestingCashFlow-21.53M59.43M-107.37M0.00
CashFlowFromContinuingInvestingActivities-21.53M59.43M-107.37M0.00
NetInvestmentPurchaseAndSale-21.49M59.56M-107.21M0.00
SaleOfInvestment76.97M69.50M19.00M0.00
PurchaseOfInvestment-98.46M-9.93M-126.22M0.00
NetPPEPurchaseAndSale-35.00K-137.00K-159.00K0.00
PurchaseOfPPE-35.00K-137.00K-159.00K0.00
OperatingCashFlow-38.26M-31.71M-28.18M-28.95M
CashFlowFromContinuingOperatingActivities-38.26M-31.71M-28.18M-28.95M
ChangeInWorkingCapital6.83M-3.85M-1.23M1.51M
ChangeInPayablesAndAccruedExpense4.17M-997.00K-630.00K1.17M
ChangeInAccruedExpense2.56M52.00K-639.00K336.00K
ChangeInPayable1.60M-1.05M9.00K831.00K
ChangeInAccountPayable1.60M-1.05M9.00K831.00K
ChangeInPrepaidAssets2.66M-2.85M-601.00K342.00K
OtherNonCashItems460.00K947.00K520.00K974.00K
StockBasedCompensation3.59M2.25M2.33M2.54M
AssetImpairmentCharge0.00390.00K0.00
AmortizationOfSecurities-1.37M-2.12M-829.00K0.00
DepreciationAmortizationDepletion147.00K123.00K43.00K50.00K
DepreciationAndAmortization147.00K123.00K43.00K50.00K
Depreciation43.00K50.00K
OperatingGainsLosses10.00K147.00K-82.00K
GainLossOnInvestmentSecurities147.00K-82.00K
GainLossOnSaleOfPPE0.0010.00K0.00
NetIncomeFromContinuingOperations-47.91M-29.07M-29.15M-33.94M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for TRVI
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