Symbols / LXRX $1.56 +2.98% Lexicon Pharmaceuticals, Inc.

Healthcare • Biotechnology • United States • NCM
LXRX Chart
About

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 658.82M
Enterprise Value 605.76M Income -50.34M Sales 49.80M
Book/sh 0.30 Cash/sh 0.23 Dividend Yield —
Payout 0.00% Employees 81 IPO —
P/E — Forward P/E -7.47 PEG —
P/S 13.23 P/B 5.25 P/C —
EV/EBITDA -12.54 EV/Sales 12.16 Quick Ratio 4.73
Current Ratio 4.88 Debt/Eq 57.87 LT Debt/Eq —
EPS (ttm) -0.14 EPS next Y -0.21 EPS Growth —
Revenue Growth -79.30% Earnings 2026-05-12 ROA -12.65%
ROE -39.72% ROIC — Gross Margin 86.82%
Oper. Margin -269.07% Profit Margin -101.08% Shs Outstand 423.68M
Shs Float 417.80M Short Float 10.56% Short Ratio 9.50
Short Interest — 52W High 1.83 52W Low 0.36
Beta 1.01 Avg Volume 2.93M Volume 1.34M
Target Price $3.36 Recom Buy Prev Close $1.51
Price $1.55 Change 2.98%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$3.36
Mean price target
2. Current target
$1.56
Latest analyst target
3. DCF / Fair value
$-2.03
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.56
Low
$1.00
High
$6.00
Mean
$3.36

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-23 reit HC Wainwright & Co. Buy → Buy $6
2026-03-10 main Citigroup Buy → Buy $2
2026-03-05 main HC Wainwright & Co. Buy → Buy $6
2025-09-02 reit HC Wainwright & Co. Buy → Buy $4
2025-08-07 main Citigroup Buy → Buy $2
2025-06-24 reit HC Wainwright & Co. Buy → Buy $4
2025-03-28 reit HC Wainwright & Co. Buy → Buy $4
2025-03-07 main Piper Sandler Overweight → Overweight $6
2025-03-07 reit Needham Hold → Hold —
2025-03-07 reit HC Wainwright & Co. Buy → Buy $4
2025-03-04 down Leerink Partners Outperform → Market Perform $1
2025-03-03 reit HC Wainwright & Co. Buy → Buy $4
2025-03-03 reit Needham Hold → Hold —
2025-01-29 reit HC Wainwright & Co. Buy → Buy $4
2025-01-29 reit Needham Hold → Hold —
2024-12-23 reit Needham Hold → Hold —
2024-11-25 reit Needham — → Hold —
2024-11-22 reit Needham — → Hold —
2024-11-13 reit HC Wainwright & Co. Buy → Buy $6
2024-11-13 reit Needham — → Hold —
News
RSS: Latest LXRX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-02-27 COIANTE SCOTT M Chief Financial Officer — 160,237 — —
2026-02-27 CRUM BRIAN T General Counsel — 273,006 — —
2026-02-27 DEFRANCESCO LISA Officer — 152,864 — —
2026-02-27 GRANOWITZ CRAIG B. M.D., PH.D. Officer — 312,276 — —
2026-02-27 MCDERMOTT WENDY Officer — 224,406 — —
2026-02-27 EXTON MICHAEL Chief Executive Officer — 503,263 — —
2026-02-27 MARTENS RACHEL YAP Officer — 67,090 — —
2026-02-27 GOPINATHAN SUMA Officer — 99,950 — —
2026-02-25 DEBBANE RAYMOND Director — 2,000 $1.49 $2,980
2026-02-23 DEBBANE RAYMOND Director — 100,000 $1.47 $147,000
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
49.80
+60.24%
31.08
+2481.48%
1.20
+766.19%
0.14
Operating Revenue
49.80
+60.24%
31.08
+2481.48%
1.20
+766.19%
0.14
Cost Of Revenue
0.27
-55.52%
0.62
+624.71%
0.09
0.00
Reconciled Cost Of Revenue
0.27
-55.52%
0.62
+624.71%
0.09
0.00
Gross Profit
49.53
+62.58%
30.46
+2622.52%
1.12
+705.04%
0.14
Operating Expense
98.44
-56.75%
227.58
+31.65%
172.87
+71.33%
100.90
Research And Development
61.12
-27.65%
84.48
+43.46%
58.89
+11.49%
52.82
Selling General And Administration
37.32
-73.92%
143.10
+25.55%
113.98
+137.05%
48.08
Total Expenses
98.71
-56.74%
228.20
+31.94%
172.95
+71.41%
100.90
Operating Income
-48.91
+75.19%
-197.12
-14.77%
-171.75
-70.45%
-100.76
Total Operating Income As Reported
-48.91
+75.19%
-197.12
-14.77%
-171.75
-70.45%
-100.76
EBITDA
-41.38
+77.55%
-184.29
-12.74%
-163.46
-65.55%
-98.74
Normalized EBITDA
-41.38
+77.55%
-184.29
-12.74%
-163.46
-65.55%
-98.74
Reconciled Depreciation
0.62
+16.29%
0.53
-3.61%
0.55
+29.74%
0.43
EBIT
-42.00
+77.27%
-184.82
-12.69%
-164.02
-65.40%
-99.16
Total Unusual Items
—
—
—
0.00
Total Unusual Items Excluding Goodwill
—
—
—
0.00
Special Income Charges
—
—
—
0.00
Impairment Of Capital Assets
—
—
—
0.00
Net Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Pretax Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Non Operating Interest Income Expense
-1.43
+56.48%
-3.29
+38.80%
-5.37
-353.46%
-1.18
Interest Expense Non Operating
8.34
-46.47%
15.58
+18.91%
13.10
+371.26%
2.78
Net Interest Income
-1.43
+56.48%
-3.29
+38.80%
-5.37
-353.46%
-1.18
Interest Expense
8.34
-46.47%
15.58
+18.91%
13.10
+371.26%
2.78
Interest Income Non Operating
6.91
-43.80%
12.29
+58.99%
7.73
+384.46%
1.60
Interest Income
6.91
-43.80%
12.29
+58.99%
7.73
+384.46%
1.60
Gain On Sale Of Business
—
—
—
0.00
Tax Provision
—
—
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income From Continuing Operation Net Minority Interest
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income From Continuing And Discontinued Operation
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income Continuous Operations
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Normalized Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income Common Stockholders
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Diluted EPS
—
-0.63
+20.25%
-0.79
-27.42%
-0.62
Basic EPS
—
-0.63
+20.25%
-0.79
-27.42%
-0.62
Basic Average Shares
—
320.03
+44.73%
221.13
+33.43%
165.73
Diluted Average Shares
—
320.03
+44.73%
221.13
+33.43%
165.73
Diluted NI Availto Com Stockholders
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
184.99
-38.01%
298.42
+30.07%
229.43
+18.08%
194.30
Current Assets
101.89
-58.61%
246.19
+39.45%
176.55
+25.33%
140.87
Cash Cash Equivalents And Short Term Investments
96.23
-59.56%
237.96
+39.95%
170.03
+22.89%
138.36
Cash And Cash Equivalents
34.33
-48.50%
66.66
+196.71%
22.46
-51.53%
46.34
Other Short Term Investments
61.90
-63.86%
171.30
+16.09%
147.56
+60.37%
92.01
Receivables
2.38
-31.36%
3.47
+243.86%
1.01
+3507.14%
0.03
Accounts Receivable
2.38
-31.36%
3.47
+243.86%
1.01
+3507.14%
0.03
Inventory
0.28
+21.65%
0.23
-39.37%
0.38
0.00
Raw Materials
—
0.10
0.00
0.00
Work In Process
—
0.00
-100.00%
0.10
0.00
Finished Goods
—
0.13
-54.45%
0.28
0.00
Prepaid Assets
—
—
—
—
Other Current Assets
3.00
-33.80%
4.53
-11.66%
5.13
+106.77%
2.48
Total Non Current Assets
83.09
+59.10%
52.23
-1.24%
52.88
-1.03%
53.43
Net PPE
9.18
+25.49%
7.32
-2.60%
7.51
-11.41%
8.48
Gross PPE
11.89
+26.44%
9.40
-21.97%
12.05
-3.31%
12.46
Accumulated Depreciation
-2.71
-29.77%
-2.09
+54.03%
-4.54
-13.91%
-3.98
Properties
0.00
0.00
0.00
0.00
Buildings And Improvements
7.32
+51.45%
4.83
-12.53%
5.52
-13.78%
6.41
Machinery Furniture Equipment
2.39
+0.00%
2.39
-44.97%
4.35
+8.59%
4.00
Other Properties
—
—
—
6.82
Leases
2.18
+0.00%
2.18
+0.00%
2.18
+6.14%
2.05
Goodwill And Other Intangible Assets
44.54
+0.00%
44.54
+0.00%
44.54
+0.00%
44.54
Goodwill
44.54
+0.00%
44.54
+0.00%
44.54
+0.00%
44.54
Other Non Current Assets
29.37
+7880.43%
0.37
-55.56%
0.83
+100.97%
0.41
Total Liabilities Net Minority Interest
77.45
-49.20%
152.47
+11.85%
136.32
+76.64%
77.17
Current Liabilities
20.87
-53.88%
45.25
+43.43%
31.55
+36.14%
23.17
Payables And Accrued Expenses
8.21
-72.02%
29.36
+42.09%
20.66
+47.06%
14.05
Payables
3.08
-79.17%
14.80
+2.86%
14.39
+38.42%
10.39
Accounts Payable
3.08
-79.17%
14.80
+2.86%
14.39
+38.42%
10.39
Current Accrued Expenses
5.13
-64.75%
14.56
+132.03%
6.28
+71.64%
3.66
Pensionand Other Post Retirement Benefit Plans Current
6.42
-56.40%
14.71
+53.39%
9.59
+22.49%
7.83
Current Debt And Capital Lease Obligation
6.24
+430.81%
1.18
-8.99%
1.29
+0.00%
1.29
Current Debt
4.59
—
—
—
Other Current Borrowings
4.59
—
—
—
Current Capital Lease Obligation
1.64
+39.74%
1.18
-8.99%
1.29
+0.00%
1.29
Total Non Current Liabilities Net Minority Interest
56.58
-47.23%
107.22
+2.34%
104.77
+94.01%
54.00
Long Term Debt And Capital Lease Obligation
56.58
-47.23%
107.22
+2.34%
104.77
+94.01%
54.00
Long Term Debt
49.41
-50.74%
100.30
+0.79%
99.51
+104.84%
48.58
Long Term Capital Lease Obligation
7.17
+3.61%
6.92
+31.51%
5.26
-2.93%
5.42
Stockholders Equity
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Common Stock Equity
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Capital Stock
0.37
+0.83%
0.36
+48.16%
0.24
+29.63%
0.19
Common Stock
0.37
+0.83%
0.36
+48.16%
0.24
+29.63%
0.19
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
365.85
+0.78%
363.02
+47.69%
245.79
+29.90%
189.21
Ordinary Shares Number
363.47
+0.55%
361.49
+47.59%
244.92
+29.78%
188.73
Treasury Shares Number
2.38
+55.89%
1.53
+76.04%
0.87
+77.86%
0.49
Additional Paid In Capital
2,129.91
+0.59%
2,117.32
+13.68%
1,862.56
+8.98%
1,709.14
Retained Earnings
-2,017.58
-2.56%
-1,967.24
-11.34%
-1,766.84
-11.14%
-1,589.72
Gains Losses Not Affecting Retained Earnings
0.03
-74.79%
0.12
+283.87%
0.03
+107.24%
-0.43
Treasury Stock
5.19
+12.39%
4.62
+59.97%
2.88
+39.98%
2.06
Other Equity Adjustments
0.03
-74.79%
0.12
+283.87%
0.03
+107.24%
-0.43
Total Equity Gross Minority Interest
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Total Capitalization
156.95
-36.27%
246.25
+27.84%
192.62
+16.24%
165.70
Working Capital
81.03
-59.68%
200.94
+38.58%
145.00
+23.20%
117.69
Invested Capital
161.54
-34.40%
246.25
+27.84%
192.62
+16.24%
165.70
Total Debt
62.82
-42.05%
108.40
+2.20%
106.06
+91.82%
55.29
Net Debt
19.68
-41.51%
33.64
-56.33%
77.04
+3348.66%
2.23
Capital Lease Obligations
8.82
+8.85%
8.10
+23.54%
6.56
-2.37%
6.71
Net Tangible Assets
62.99
-37.88%
101.41
+108.80%
48.57
-33.09%
72.58
Tangible Book Value
62.99
-37.88%
101.41
+108.80%
48.57
-33.09%
72.58
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-67.85
+62.05%
-178.78
-10.43%
-161.90
-82.21%
-88.85
Cash Flow From Continuing Operating Activities
-67.85
+62.05%
-178.78
-10.43%
-161.90
-82.21%
-88.85
Net Income From Continuing Operations
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Depreciation Amortization Depletion
0.62
+16.29%
0.53
-3.61%
0.55
+29.74%
0.43
Depreciation And Amortization
0.62
+16.29%
0.53
-3.61%
0.55
+29.74%
0.43
Other Non Cash Items
-0.04
-101.58%
2.66
-19.14%
3.29
+343.45%
0.74
Stock Based Compensation
12.52
-7.27%
13.50
-5.86%
14.34
+24.48%
11.52
Asset Impairment Charge
—
—
—
0.00
Deferred Tax
—
—
—
—
Deferred Income Tax
—
—
—
—
Operating Gains Losses
—
—
—
0.00
Gain Loss On Sale Of PPE
—
0.00
0.00
-100.00%
0.00
Change In Working Capital
-26.89
-288.89%
14.24
+435.46%
2.66
+561.44%
0.40
Change In Receivables
1.09
+144.21%
-2.46
-150.81%
-0.98
-6914.29%
-0.01
Changes In Account Receivables
1.09
+144.21%
-2.46
-150.81%
-0.98
-6914.29%
-0.01
Change In Inventory
-0.05
-133.33%
0.15
+139.37%
-0.38
0.00
Change In Prepaid Assets
1.53
+156.19%
0.60
+120.63%
-2.90
-817.41%
-0.32
Change In Payables And Accrued Expense
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Payable
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Account Payable
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Other Current Assets
0.76
-34.29%
1.15
+146.68%
0.47
-28.81%
0.66
Investing Cash Flow
113.02
+834.95%
-15.38
+69.21%
-49.94
+29.73%
-71.08
Cash Flow From Continuing Investing Activities
113.02
+834.95%
-15.38
+69.21%
-49.94
+29.73%
-71.08
Net PPE Purchase And Sale
0.00
+100.00%
-1.03
-119.36%
-0.47
+64.56%
-1.33
Purchase Of PPE
0.00
+100.00%
-1.03
-119.36%
-0.47
+64.56%
-1.33
Sale Of PPE
—
—
—
0.00
Capital Expenditure
—
-1.03
-119.36%
-0.47
+64.56%
-1.33
Net Investment Purchase And Sale
113.02
+887.76%
-14.35
+71.00%
-49.47
+29.07%
-69.75
Purchase Of Investment
-139.84
+57.46%
-328.75
-47.19%
-223.34
-66.74%
-133.95
Sale Of Investment
252.86
-19.57%
314.40
+80.82%
173.87
+170.84%
64.20
Net Business Purchase And Sale
—
—
—
0.00
Gain Loss On Sale Of Business
—
—
—
0.00
Financing Cash Flow
-48.50
-120.35%
238.35
+26.81%
187.96
+32.17%
142.21
Cash Flow From Continuing Financing Activities
-48.50
-120.35%
238.35
+26.81%
187.96
+32.17%
142.21
Net Issuance Payments Of Debt
-48.00
0.00
-100.00%
49.96
+2.24%
48.87
Issuance Of Debt
0.00
0.00
-100.00%
49.96
+2.24%
48.87
Repayment Of Debt
-48.00
0.00
0.00
—
Long Term Debt Issuance
0.00
0.00
-100.00%
49.96
+2.24%
48.87
Long Term Debt Payments
-48.00
0.00
0.00
—
Net Long Term Debt Issuance
-48.00
0.00
-100.00%
49.96
+2.24%
48.87
Net Common Stock Issuance
-0.57
+66.94%
-1.73
-101.25%
138.00
+47.84%
93.34
Common Stock Payments
-0.57
+66.94%
-1.73
-109.95%
-0.82
+4.63%
-0.86
Repurchase Of Capital Stock
-0.57
+66.94%
-1.73
-109.95%
-0.82
+4.63%
-0.86
Proceeds From Stock Option Exercised
0.07
+14.06%
0.06
0.00
0.00
Net Other Financing Charges
—
-1.31
—
—
Changes In Cash
-3.33
-107.54%
44.19
+285.05%
-23.88
-34.76%
-17.72
Beginning Cash Position
66.66
+196.71%
22.46
-51.53%
46.34
-27.66%
64.06
End Cash Position
63.33
-5.00%
66.66
+196.71%
22.46
-51.53%
46.34
Free Cash Flow
-67.85
+62.27%
-179.81
-10.74%
-162.37
-80.05%
-90.18
Interest Paid Supplemental Data
8.33
-35.52%
12.92
+28.46%
10.06
+339.36%
2.29
Amortization Of Securities
-3.71
+60.11%
-9.30
-65.66%
-5.62
0.00
Common Stock Issuance
0.00
0.00
-100.00%
138.82
+47.36%
94.20
Issuance Of Capital Stock
0.00
-100.00%
241.32
+73.83%
138.82
+47.36%
94.20
Net Preferred Stock Issuance
0.00
-100.00%
241.32
0.00
0.00
Preferred Stock Issuance
0.00
-100.00%
241.32
0.00
0.00
Sale Of Business
—
—
—
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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