OLMA Chart
About

Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. The company's lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors palbociclib and ribociclib, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, and with an mTOR inhibitor everolimus that is in Phase 1/2 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive human epidermal growth factor receptor 2-negative breast cancer. It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 for patients with ER+/HER2- metastatic breast cancer and other cancers which is in Phase 1 clinical trial. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009. Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 1.98B
Enterprise Value 1.37B Income -149.96M Sales —
Book/sh 4.48 Cash/sh 4.79 Dividend Yield —
Payout 0.00% Employees 122 IPO —
P/E — Forward P/E -10.69 PEG —
P/S — P/B 5.51 P/C —
EV/EBITDA -8.57 EV/Sales — Quick Ratio 7.97
Current Ratio 8.03 Debt/Eq 1.46 LT Debt/Eq —
EPS (ttm) -1.76 EPS next Y -2.31 EPS Growth —
Revenue Growth — Earnings 2026-03-24 ROA -34.41%
ROE -59.23% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 80.16M
Shs Float 55.33M Short Float 13.68% Short Ratio 8.67
Short Interest — 52W High 36.26 52W Low 2.86
Beta 1.92 Avg Volume 1.95M Volume 1.61M
Target Price $46.09 Recom Strong_buy Prev Close $24.36
Price $24.69 Change 1.35%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$46.09
Mean price target
2. Current target
$24.69
Latest analyst target
3. DCF / Fair value
$-16.03
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$24.69
Low
$38.00
High
$60.00
Mean
$46.09

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-02-11 init Stifel — → Buy $48
2026-01-07 init UBS — → Buy $45
2026-01-07 init Piper Sandler — → Overweight —
2025-12-12 main Citigroup Buy → Buy $60
2025-12-11 main Oppenheimer Outperform → Outperform $48
2025-12-11 main Goldman Sachs Buy → Buy $38
2025-12-11 main HC Wainwright & Co. Buy → Buy $45
2025-11-21 main Goldman Sachs Buy → Buy $26
2025-11-18 main Oppenheimer Outperform → Outperform $45
2025-11-18 main HC Wainwright & Co. Buy → Buy $36
2025-11-18 main JP Morgan Overweight → Overweight $32
2025-10-20 reit HC Wainwright & Co. Buy → Buy $28
2025-10-08 init Guggenheim — → Buy $20
2025-09-03 main Oppenheimer Outperform → Outperform $22
2025-08-14 main JP Morgan Overweight → Overweight $29
2025-08-12 main Citigroup Buy → Buy $21
2025-05-14 main Goldman Sachs Buy → Buy $18
2025-05-14 main Oppenheimer Outperform → Outperform $22
2025-04-28 reit HC Wainwright & Co. Buy → Buy $30
2025-03-28 main JP Morgan Overweight → Overweight $28
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 11700 — — Stock Award(Grant) at price 0.00 per share. AUSTIN SASHA LU Officer — 2026-02-02 00:00:00 D
1 10000 268800 — Sale at price 26.88 per share. HARMON CYRUS Director — 2026-01-20 00:00:00 D
2 103822 2980054 — Sale at price 28.01 - 28.73 per share. KOVACS SHANE WILLIAM CHARLES Chief Operating Officer — 2026-01-15 00:00:00 D
3 3489 101600 — Sale at price 29.12 per share. HARMON CYRUS Director — 2026-01-14 00:00:00 D
4 110000 3107229 — Sale at price 27.60 - 28.99 per share. MYLES DAVID C Officer — 2026-01-14 00:00:00 D/I
5 100000 487000 — Conversion of Exercise of derivative security at price 4.87 per share. MYLES DAVID C Officer — 2026-01-14 00:00:00 D
6 8500 — — Stock Gift at price 0.00 per share. BOHEN SEAN Chief Executive Officer — 2025-12-26 00:00:00 D
7 269509 7530148 — Sale at price 27.66 - 28.93 per share. ZOJWALLA NASEEM M.D. Officer — 2025-12-23 00:00:00 D
8 140000 1664392 — Conversion of Exercise of derivative security at price 7.02 - 15.25 per share. ZOJWALLA NASEEM M.D. Officer — 2025-12-23 00:00:00 D
9 2881 82195 — Sale at price 28.53 per share. HARMON CYRUS Director — 2025-12-22 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-141.87M-104.58M-106.63M-71.33M
NetIncomeFromContinuingOperationNetMinorityInterest-129.47M-96.66M-104.79M-71.10M
ReconciledDepreciation393.00K377.00K357.00K163.00K
EBITDA-141.87M-104.58M-106.63M-71.33M
EBIT-142.26M-104.96M-106.99M-71.49M
NetInterestIncome12.68M8.32M2.23M442.00K
InterestExpense0.00
InterestIncome12.68M8.32M2.23M442.00K
NormalizedIncome-129.47M-96.66M-104.79M-71.10M
NetIncomeFromContinuingAndDiscontinuedOperation-129.47M-96.66M-104.79M-71.10M
TotalExpenses142.26M104.96M106.99M71.49M
TotalOperatingIncomeAsReported-142.26M-104.96M-106.99M-71.49M
DilutedAverageShares58.74M45.25M40.00M39.52M
BasicAverageShares58.74M45.25M40.00M39.52M
DilutedEPS-2.20-2.14-2.62-1.80
BasicEPS-2.20-2.14-2.62-1.80
DilutedNIAvailtoComStockholders-129.47M-96.66M-104.79M-71.10M
NetIncomeCommonStockholders-129.47M-96.66M-104.79M-71.10M
OtherunderPreferredStockDividend0.00
NetIncome-129.47M-96.66M-104.79M-71.10M
NetIncomeIncludingNoncontrollingInterests-129.47M-96.66M-104.79M-71.10M
NetIncomeContinuousOperations-129.47M-96.66M-104.79M-71.10M
PretaxIncome-129.47M-96.66M-104.79M-71.10M
OtherIncomeExpense102.00K-19.00K-27.00K-47.00K
OtherNonOperatingIncomeExpenses102.00K-19.00K-27.00K-47.00K
NetNonOperatingInterestIncomeExpense12.68M8.32M2.23M442.00K
InterestExpenseNonOperating0.00
InterestIncomeNonOperating12.68M8.32M2.23M442.00K
OperatingIncome-142.26M-104.96M-106.99M-71.49M
OperatingExpense142.26M104.96M106.99M71.49M
ResearchAndDevelopment124.52M86.14M82.27M51.10M
SellingGeneralAndAdministration17.74M18.82M24.71M20.39M
GeneralAndAdministrativeExpense17.74M18.82M24.71M20.39M
OtherGandA17.74M18.82M24.71M20.39M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2023-12-31
TreasurySharesNumber104.33K
OrdinarySharesNumber74.31M54.99M40.29M39.80M
ShareIssued74.31M55.10M40.29M39.80M
TotalDebt1.43M2.42M2.56M3.29M
TangibleBookValue408.96M253.90M197.55M284.57M
InvestedCapital408.96M253.90M197.55M284.57M
WorkingCapital396.71M244.89M192.35M281.67M
NetTangibleAssets408.96M253.90M197.55M284.57M
CapitalLeaseObligations1.43M2.42M2.56M3.29M
CommonStockEquity408.96M253.90M197.55M284.57M
TotalCapitalization408.96M253.90M197.55M284.57M
TotalEquityGrossMinorityInterest408.96M253.90M197.55M284.57M
StockholdersEquity408.96M253.90M197.55M284.57M
GainsLossesNotAffectingRetainedEarnings143.00K347.00K-1.81M-149.00K
OtherEquityAdjustments143.00K347.00K-1.81M-149.00K
RetainedEarnings-435.11M-305.63M-208.98M-104.19M
AdditionalPaidInCapital843.92M559.18M408.33M388.90M
CapitalStock6.00K4.00K3.00K3.00K
CommonStock6.00K4.00K3.00K3.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest42.02M23.05M18.10M11.38M
TotalNonCurrentLiabilitiesNetMinorityInterest257.00K1.43M1.55M2.36M
LongTermDebtAndCapitalLeaseObligation257.00K1.43M1.55M2.36M
LongTermCapitalLeaseObligation257.00K1.43M1.55M2.36M
CurrentLiabilities41.76M21.62M16.55M9.02M
OtherCurrentLiabilities82.00K206.00K
CurrentDebtAndCapitalLeaseObligation1.17M988.00K1.01M931.00K
CurrentCapitalLeaseObligation1.17M988.00K1.01M931.00K
PensionandOtherPostRetirementBenefitPlansCurrent5.66M5.46M4.52M3.75M
PayablesAndAccruedExpenses34.92M15.17M10.93M4.13M
CurrentAccruedExpenses30.42M12.40M10.49M4.02M
Payables4.50M2.77M442.00K111.00K
TotalTaxPayable41.00K73.00K68.00K88.00K
AccountsPayable4.46M2.70M374.00K23.00K
TotalAssets450.98M276.94M215.65M295.94M
TotalNonCurrentAssets12.51M10.43M6.75M5.26M
OtherNonCurrentAssets698.00K2.77M540.00K
NonCurrentPrepaidAssets9.75M7.17M2.77M
NetPPE2.06M3.26M3.98M4.72M
AccumulatedDepreciation-581.00K-224.00K
GrossPPE2.06M3.26M3.98M4.94M
OtherProperties2.06M3.26M3.98M4.88M
MachineryFurnitureEquipment59.00K59.00K
CurrentAssets438.47M266.51M208.90M290.69M
OtherCurrentAssets366.00K1.68M1.52M223.00K
PrepaidAssets1.90M2.35M2.64M3.31M
Receivables2.12M673.00K319.00K130.00K
AccruedInterestReceivable2.12M673.00K319.00K130.00K
CashCashEquivalentsAndShortTermInvestments434.09M261.81M204.42M287.25M
OtherShortTermInvestments294.61M193.27M180.72M273.44M
CashAndCashEquivalents139.48M68.54M23.70M13.81M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-104.51M-83.73M-82.43M-52.27M
RepurchaseOfCapitalStock0.00
IssuanceOfDebt0.00
IssuanceOfCapitalStock266.29M129.74M0.000.00
CapitalExpenditure-159.00K-363.00K-1.57M
EndCashPosition139.48M68.54M23.70M13.81M
BeginningCashPosition68.54M23.70M13.81M338.55M
ChangesInCash70.94M44.84M9.89M-324.74M
FinancingCashFlow268.82M133.41M476.00K1.39M
CashFlowFromContinuingFinancingActivities268.82M133.41M476.00K1.39M
ProceedsFromStockOptionExercised2.53M3.68M476.00K1.39M
NetPreferredStockIssuance0.00
PreferredStockPayments0.00
PreferredStockIssuance0.00
NetCommonStockIssuance266.29M129.74M0.000.00
CommonStockIssuance266.29M129.74M0.000.00
NetIssuancePaymentsOfDebt0.00
NetLongTermDebtIssuance0.00
LongTermDebtIssuance0.00
InvestingCashFlow-93.53M-4.85M91.48M-275.44M
CashFlowFromContinuingInvestingActivities-93.53M-4.85M91.48M-275.44M
NetInvestmentPurchaseAndSale-93.37M-4.87M91.84M-273.86M
SaleOfInvestment301.59M250.76M305.50M213.10M
PurchaseOfInvestment-394.96M-255.62M-213.66M-486.97M
NetPPEPurchaseAndSale-159.00K14.00K-363.00K-1.57M
SaleOfPPE0.0014.00K0.00
PurchaseOfPPE-159.00K0.00-363.00K-1.57M
OperatingCashFlow-104.35M-83.73M-82.06M-50.69M
CashFlowFromContinuingOperatingActivities-104.35M-83.73M-82.06M-50.69M
ChangeInWorkingCapital9.16M-589.00K3.02M2.83M
ChangeInOtherCurrentLiabilities10.04M1.72M5.74M3.58M
ChangeInOtherCurrentAssets-2.96M-5.32M-1.11M-30.00K
ChangeInPayablesAndAccruedExpense2.51M2.32M351.00K-683.00K
ChangeInPayable2.51M2.32M351.00K-683.00K
ChangeInAccountPayable2.51M2.32M351.00K-683.00K
ChangeInPrepaidAssets-429.00K694.00K-1.96M-40.00K
OtherNonCashItems-7.03M-4.23M514.00K1.22M
StockBasedCompensation22.58M17.26M18.83M15.91M
AmortizationOfSecurities-787.00K276.00K
DepreciationAmortizationDepletion393.00K377.00K357.00K163.00K
DepreciationAndAmortization393.00K377.00K357.00K163.00K
OperatingGainsLosses9.00K111.00K
GainLossOnSaleOfPPE9.00K111.00K0.00
NetIncomeFromContinuingOperations-129.47M-96.66M-104.79M-71.10M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for OLMA
Date User Asset Broker Type Position Size Entry Price Patterns