PMN Chart
About

ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS and Collective Coordinates algorithms to predict novel targets known as disease specific epitopes on the molecular surface of misfolded proteins. Its lead product candidates comprise of PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer's Disease; PMN267 for treatment of amyotrophic lateral sclerosis; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils for treating multiple system atrophy. The company also develops PNM440, an alpha-synuclein vaccine for treating multiple synucleinopathies; and PMN311, an amyloid-beta vaccine for treatment of Alzheimer's. In addition, it is developing therapies for frontotemporal lobar degeneration, Huntington's disease, progressive supranuclear palsy, corticobasal degeneration, and schizophrenia. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. is headquartered in Toronto, Canada.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 43.39M
Enterprise Value 27.96M Income -29.28M Sales
Book/sh 4.27 Cash/sh 7.17 Dividend Yield
Payout 0.00% Employees 7 IPO
P/E Forward P/E -33.05 PEG
P/S P/B 4.72 P/C
EV/EBITDA EV/Sales Quick Ratio 1.27
Current Ratio 1.76 Debt/Eq LT Debt/Eq
EPS (ttm) -20.00 EPS next Y -0.61 EPS Growth
Revenue Growth Earnings 2025-11-12 07:00 ROA -85.38%
ROE -3.56% ROIC Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 2.15M
Shs Float 1.27M Short Float 5.47% Short Ratio 0.25
Short Interest 52W High 39.75 52W Low 6.27
Beta -0.40 Avg Volume 179.58K Volume 88.91K
Target Price $34.42 Recom None Prev Close $18.15
Price $20.16 Change 11.07%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$34.43
Mean price target
2. Current target
$20.16
Latest analyst target
3. DCF / Fair value
$-99.13
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$20.16
Low
$18.20
High
$49.44
Mean
$34.43

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-02-06 main Guggenheim Buy → Buy $35
2025-12-01 main HC Wainwright & Co. Buy → Buy $18
2025-11-21 reit HC Wainwright & Co. Buy → Buy $4
2025-11-18 main Guggenheim Buy → Buy $5
2025-07-14 init HC Wainwright & Co. — → Buy $4
2025-05-12 init Maxim Group — → Buy $3
2025-04-01 reit Guggenheim Buy → Buy $6
2025-02-26 reit Guggenheim Buy → Buy
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 2000 48800.0 Purchase at price 24.40 per share. WILLIAMS EUGENE WARREN Director 2026-03-05 00:00:00 D
1 4000 92420.0 Purchase at price 21.89 - 24.00 per share. WILLIAMS EUGENE WARREN Director 2026-03-04 00:00:00 D
2 1629 25005.0 Purchase at price 15.35 per share. KAPLAN JOHANNE Officer 2026-02-19 00:00:00 D
3 6183 98310.0 Stock Award(Grant) at price 15.90 per share. WARMA NEIL K Chief Executive Officer 2026-02-03 00:00:00 D
4 3050 48495.0 Stock Award(Grant) at price 15.90 per share. KIRWIN PATRICK D Director 2026-02-03 00:00:00 D
5 6595 104860.0 Stock Award(Grant) at price 15.90 per share. MILBURY MAX A. Officer 2026-02-03 00:00:00 D
6 2060 32754.0 Stock Award(Grant) at price 15.90 per share. KAPLAN JOHANNE Officer 2026-02-03 00:00:00 D
7 4122 65540.0 Stock Award(Grant) at price 15.90 per share. CASHMAN NEIL Officer and Director 2026-02-03 00:00:00 I
8 700741 11141782.0 Purchase at price 15.90 per share. ABG MANAGEMENT, LTD. Beneficial Owner of more than 10% of a Class of Security 2026-02-03 00:00:00 I
9 30392 14929.0 Purchase at price 0.49 per share. MILBURY MAX A. Officer 2025-10-03 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems3.39M0.000.000.00
TaxRateForCalcs0.150.000.000.00
NormalizedEBITDA-19.73M-13.86M-23.25M-8.23M
TotalUnusualItems22.58M866.74K5.48M-1.10M
TotalUnusualItemsExcludingGoodwill22.58M866.74K5.48M-1.10M
NetIncomeFromContinuingOperationNetMinorityInterest2.78M-13.21M-18.06M-9.79M
ReconciledDepreciation0.0021.16K11.22K45.83K
EBITDA2.86M-12.99M-17.77M-9.33M
EBIT2.86M-13.01M-17.78M-9.37M
NetInterestIncome-76.78K-201.39K-282.06K-416.29K
InterestExpense76.78K201.39K282.06K416.29K
InterestIncome4.73K
NormalizedIncome-16.42M-14.08M-23.55M-8.69M
NetIncomeFromContinuingAndDiscontinuedOperation2.78M-13.21M-18.06M-9.79M
TotalExpenses16.83M14.26M23.38M8.29M
TotalOperatingIncomeAsReported-16.83M-14.26M-23.38M-8.29M
DilutedAverageShares1.06M491.71K300.10K231.42K
BasicAverageShares1.04M491.71K300.10K231.42K
DilutedEPS2.75-26.75-60.25-42.25
BasicEPS2.75-26.75-60.25-42.25
DilutedNIAvailtoComStockholders2.78M-13.21M-18.06M-9.79M
NetIncomeCommonStockholders2.78M-13.21M-18.06M-9.79M
NetIncome2.78M-13.21M-18.06M-9.79M
NetIncomeIncludingNoncontrollingInterests2.78M-13.21M-18.06M-9.79M
NetIncomeContinuousOperations2.78M-13.21M-18.06M-9.79M
PretaxIncome2.78M-13.21M-18.06M-9.79M
OtherIncomeExpense19.68M1.25M5.60M-1.08M
OtherNonOperatingIncomeExpenses-2.90M384.90K115.53K12.91K
SpecialIncomeCharges0.001.31M0.00
GainOnSaleOfPPE58.98K
OtherSpecialCharges-1.31M
GainOnSaleOfSecurity22.58M866.74K4.18M-1.10M
NetNonOperatingInterestIncomeExpense-76.78K-201.39K-282.06K-416.29K
InterestExpenseNonOperating76.78K201.39K282.06K416.29K
InterestIncomeNonOperating4.73K
OperatingIncome-16.83M-14.26M-23.38M-8.29M
OperatingExpense16.83M14.26M23.38M8.29M
ResearchAndDevelopment10.64M7.88M16.09M4.63M
SellingGeneralAndAdministration6.19M6.38M7.29M3.66M
GeneralAndAdministrativeExpense6.19M6.38M7.29M3.66M
OtherGandA6.19M6.38M7.29M3.66M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2023-12-31
TreasurySharesNumber0.00
OrdinarySharesNumber1.31M755.41K343.17K287.82K
ShareIssued1.31M755.41K343.17K287.82K
TotalDebt3.91M
TangibleBookValue16.49M3.75M-1.37M5.63M
InvestedCapital16.49M3.75M-1.35M9.57M
WorkingCapital16.69M4.27M490.44K16.79M
NetTangibleAssets16.49M3.75M-1.37M5.63M
CommonStockEquity16.49M3.75M-1.35M5.66M
TotalCapitalization16.49M3.75M-1.35M9.57M
TotalEquityGrossMinorityInterest16.49M3.75M-1.35M5.66M
StockholdersEquity16.49M3.75M-1.35M5.66M
OtherEquityInterest6.93M
GainsLossesNotAffectingRetainedEarnings-371.18K-371.18K-195.37K-187.92K
OtherEquityAdjustments-371.18K-371.18K-195.37K-187.92K
RetainedEarnings-90.69M-93.47M-80.25M-62.19M
AdditionalPaidInCapital107.55M97.59M79.10M68.04M
CapitalStock0.000.000.000.00
CommonStock0.000.000.000.00
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest2.42M9.87M8.27M12.09M
TotalNonCurrentLiabilitiesNetMinorityInterest204.85K516.19K1.86M11.16M
DerivativeProductLiabilities5.59K94.19K1.86M7.25M
EmployeeBenefits199.26K422.00K0.00
LongTermDebtAndCapitalLeaseObligation3.91M
LongTermDebt3.91M
CurrentLiabilities2.22M9.35M6.41M929.07K
CurrentDeferredLiabilities0.00
PensionandOtherPostRetirementBenefitPlansCurrent38.33K518.70K0.00
PayablesAndAccruedExpenses2.18M8.83M6.41M929.07K
CurrentAccruedExpenses442.63K987.82K3.44M520.09K
InterestPayable0.0054.40K
Payables1.74M7.84M2.98M408.98K
AccountsPayable1.74M7.84M2.98M408.98K
TotalAssets18.91M13.62M6.92M17.75M
TotalNonCurrentAssets0.000.0021.16K32.28K
InvestmentsAndAdvances0.00
LongTermEquityInvestment0.00
InvestmentsinJointVenturesatCost0.00
GoodwillAndOtherIntangibleAssets0.0020.84K27.61K
NetPPE0.00321.004.67K
AccumulatedDepreciation-80.00K-79.39K
GrossPPE80.32K84.06K
OtherProperties61.93K66.40K
MachineryFurnitureEquipment18.39K17.66K
CurrentAssets18.91M13.62M6.90M17.71M
OtherCurrentAssets47.28K33.22K4.62K4.39K
CurrentDeferredAssets0.00195.63K0.00
PrepaidAssets5.46M681.15K920.43K684.24K
Receivables78.03K78.64K71.63K48.69K
OtherReceivables4.62K
TaxesReceivable20.48K71.63K48.69K
AccruedInterestReceivable78.03K78.64K0.00
CashCashEquivalentsAndShortTermInvestments13.32M12.63M5.91M16.98M
OtherShortTermInvestments33.05K32.36K31.01K33.25K
CashAndCashEquivalents13.29M12.60M5.88M16.94M
CashFinancial13.29M12.60M5.88M16.94M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-27.18M-10.84M-17.04M-9.31M
RepurchaseOfCapitalStock-1.64M
IssuanceOfDebt0.006.92M
IssuanceOfCapitalStock27.85M17.75M4.97M15.87M
CapitalExpenditure-1.98K-6.04K
InterestPaidSupplementalData76.78K201.39K87.07K
EndCashPosition13.29M12.60M5.88M16.94M
BeginningCashPosition12.60M5.88M16.94M806.89K
EffectOfExchangeRateChanges0.00-181.43K-526.90K-175.02K
ChangesInCash693.02K6.90M-10.54M16.31M
FinancingCashFlow27.88M17.75M6.49M25.52M
CashFlowFromContinuingFinancingActivities27.88M17.75M6.49M25.52M
ProceedsFromStockOptionExercised28.04K3.60K1.52M2.74M
NetCommonStockIssuance27.85M17.75M4.97M15.87M
CommonStockPayments-1.64M
CommonStockIssuance27.85M17.75M4.97M15.87M
NetIssuancePaymentsOfDebt0.006.92M
NetLongTermDebtIssuance0.006.92M
LongTermDebtIssuance0.006.92M
InvestingCashFlow-693.00-1.35K-1.98K94.62K
CashFlowFromContinuingInvestingActivities-693.00-1.35K-1.98K94.62K
NetOtherInvestingChanges2.36K
NetInvestmentPurchaseAndSale-693.00-1.35K0.00-33.00
SaleOfInvestment32.36K31.01K31.01K33.07K
PurchaseOfInvestment-33.05K-32.36K-31.01K-33.10K
NetBusinessPurchaseAndSale2.35K
SaleOfBusiness2.35K
NetPPEPurchaseAndSale0.00-1.98K92.29K
SaleOfPPE0.0098.33K
PurchaseOfPPE0.00-1.98K-6.04K
OperatingCashFlow-27.18M-10.84M-17.03M-9.31M
CashFlowFromContinuingOperatingActivities-27.18M-10.84M-17.03M-9.31M
ChangeInWorkingCapital-11.73M2.94M5.40M-1.56M
ChangeInOtherWorkingCapital-1.40M
ChangeInPayablesAndAccruedExpense-7.13M3.13M5.72M439.81K
ChangeInAccruedExpense-1.03M-1.83M3.05M471.46K
ChangeInPayable-6.11M4.96M2.68M-31.65K
ChangeInAccountPayable-6.11M4.96M2.68M-31.65K
ChangeInPrepaidAssets-4.60M-187.32K-318.75K-600.63K
ChangeInReceivables-17.28K
OtherNonCashItems3.52M241.85K366.02K
StockBasedCompensation825.81K271.54K487.63K515.63K
DepreciationAmortizationDepletion0.0021.16K11.22K45.83K
DepreciationAndAmortization0.0021.16K11.22K45.83K
AmortizationCashFlow0.0020.84K5.07K5.25K
AmortizationOfIntangibles0.0020.84K5.07K5.25K
Depreciation0.00321.006.14K40.58K
OperatingGainsLosses-22.58M-868.55K-5.11M1.12M
GainLossOnInvestmentSecurities-22.58M-866.74K-4.11M1.10M
NetForeignCurrencyExchangeGainLoss0.00-1.82K305.41K85.07K
GainLossOnSaleOfPPE0.00-59.16K
NetIncomeFromContinuingOperations2.78M-13.21M-18.06M-9.79M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for PMN
Date User Broker Pattern Type Position Size Entry Price Trade P&L Status