Symbols / PSTV $3.33 -6.46% Plus Therapeutics, Inc.

Healthcare • Biotechnology • United States • NCM
PSTV Chart
About

Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. The company's lead radiotherapeutic candidate is rhenium obisbemeda, a patented radiotherapy for patients with central nervous system and other cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers. It also develops Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere to treat various solid organ cancers, such as primary and secondary liver cancers by intra-arterial injection. In addition, it develops and commercializes laboratory-developed tests comprising the CNSide Test to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The company was formerly known as Cytori Therapeutics, Inc. and changed its name to Plus Therapeutics, Inc. in July 2019. Plus Therapeutics, Inc. was founded in 1996 and is headquartered in Houston, Texas.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 22.85M
Enterprise Value 16.64M Income -22.39M Sales 5.21M
Book/sh 0.72 Cash/sh 1.25 Dividend Yield —
Payout 0.00% Employees 28 IPO —
P/E — Forward P/E -1.48 PEG —
P/S 4.38 P/B 4.62 P/C —
EV/EBITDA -1.12 EV/Sales 3.19 Quick Ratio 0.73
Current Ratio 1.23 Debt/Eq 20.55 LT Debt/Eq —
EPS (ttm) -7.25 EPS next Y -2.25 EPS Growth —
Revenue Growth -3.20% Earnings 2026-03-04 ROA -83.29%
ROE — ROIC — Gross Margin -60.73%
Oper. Margin -4.20% Profit Margin 0.00% Shs Outstand 6.86M
Shs Float 6.34M Short Float 11.73% Short Ratio 4.36
Short Interest — 52W High 30.50 52W Low 3.25
Beta 1.02 Avg Volume 424.84K Volume 550.00K
Target Price $146.88 Recom Buy Prev Close $3.56
Price $3.33 Change -6.46%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$146.88
Mean price target
2. Current target
$3.33
Latest analyst target
3. DCF / Fair value
$-35.67
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$3.33
Low
$25.00
High
$475.00
Mean
$146.88

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-31 down D. Boral Capital Buy → Hold —
2026-03-19 main D. Boral Capital Buy → Buy $3
2026-01-23 main HC Wainwright & Co. Buy → Buy $1
2026-01-22 main D. Boral Capital Buy → Buy $4
2026-01-08 main D. Boral Capital Buy → Buy $5
2025-12-11 main D. Boral Capital Buy → Buy $5
2025-12-01 main D. Boral Capital Buy → Buy $5
2025-11-21 main Ascendiant Capital Buy → Buy $19
2025-11-20 main D. Boral Capital Buy → Buy $5
2025-11-03 main HC Wainwright & Co. Buy → Buy $2
2025-10-31 main D. Boral Capital Buy → Buy $5
2025-10-21 main D. Boral Capital Buy → Buy $5
2025-10-06 main Ascendiant Capital Buy → Buy $21
2025-09-25 main D. Boral Capital Buy → Buy $5
2025-09-22 main D. Boral Capital Buy → Buy $5
2025-09-18 main D. Boral Capital Buy → Buy $5
2025-09-03 up D. Boral Capital Hold → Buy $5
2025-08-18 main Maxim Group Buy → Buy $3
2025-06-27 main HC Wainwright & Co. Buy → Buy $3
2025-06-25 main D. Boral Capital Hold → Hold $9
News
RSS: Latest PSTV news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-04-01 HEDRICK MARC HAMILTON Chief Executive Officer — 361,313 — —
2026-04-01 SIMS ANDREW JOHN HUGH MACINTYRE Chief Financial Officer — 67,452 — —
2025-12-31 HEDRICK MARC HAMILTON Chief Executive Officer — 159,681 — —
2025-12-31 SIMS ANDREW JOHN HUGH MACINTYRE Chief Financial Officer — 38,323 — —
2025-11-04 SIMS ANDREW JOHN HUGH MACINTYRE Chief Financial Officer — 20,000 $0.51 $10,200
2025-10-01 HEDRICK MARC HAMILTON Chief Executive Officer — 159,681 — —
2025-10-01 SIMS ANDREW JOHN HUGH MACINTYRE Chief Financial Officer — 38,323 — —
2025-08-22 LENK ROBERT P Director — 110,000 $0.49 $53,779
2024-09-13 HAWKINS RICHARD JAMES Director — 4,000 $1.50 $5,996
2024-09-12 HAWKINS RICHARD JAMES Director — 6,285 $1.35 $8,512
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
15.30
+4.10%
14.70
+10.31%
13.32
-32.42%
19.71
Research And Development
8.38
-20.80%
10.58
+9.18%
9.69
-0.08%
9.70
Selling General And Administration
12.13
+22.06%
9.94
+16.33%
8.54
-16.55%
10.24
General And Administrative Expense
12.13
+22.06%
9.94
+16.33%
8.54
-16.55%
10.24
Salaries And Wages
—
—
—
0.52
Other Gand A
12.13
+22.06%
9.94
+16.33%
8.54
-16.55%
10.24
Other Operating Expenses
-5.21
+10.49%
-5.82
-18.54%
-4.91
-2093.30%
-0.22
Total Expenses
15.30
+4.10%
14.70
+10.31%
13.32
-32.42%
19.71
Operating Income
-15.30
-4.10%
-14.70
-10.31%
-13.32
+32.42%
-19.71
Total Operating Income As Reported
-15.30
-4.10%
-14.70
-10.31%
-13.32
+32.42%
-19.71
EBITDA
-18.33
-118.71%
-8.38
+31.81%
-12.29
+35.11%
-18.95
Normalized EBITDA
-15.70
-11.86%
-14.04
-14.18%
-12.29
+35.11%
-18.95
Reconciled Depreciation
0.45
-48.97%
0.87
+38.85%
0.63
+1.45%
0.62
EBIT
-18.78
-102.91%
-9.25
+28.38%
-12.92
+33.96%
-19.56
Total Unusual Items
-2.63
-146.53%
5.65
—
0.00
Total Unusual Items Excluding Goodwill
-2.63
-146.53%
5.65
—
0.00
Special Income Charges
—
—
—
0.00
Net Income
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Pretax Income
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Net Non Operating Interest Income Expense
-3.49
-1.22%
-3.45
-69120.00%
0.01
+100.89%
-0.56
Interest Expense Non Operating
3.61
-3.09%
3.72
+842.78%
0.40
-44.44%
0.71
Net Interest Income
-3.49
-1.22%
-3.45
-69120.00%
0.01
+100.89%
-0.56
Interest Expense
3.61
-3.09%
3.72
+842.78%
0.40
-44.44%
0.71
Interest Income Non Operating
0.12
-57.51%
0.27
-31.75%
0.40
+172.11%
0.15
Interest Income
0.12
-57.51%
0.27
-31.75%
0.40
+172.11%
0.15
Other Income Expense
-3.60
-169.56%
5.17
—
0.00
Other Non Operating Income Expenses
-0.96
-98.35%
-0.49
—
0.00
Gain On Sale Of Security
-2.63
-146.53%
5.65
—
0.00
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Net Income From Continuing Operation Net Minority Interest
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Net Income From Continuing And Discontinued Operation
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Net Income Continuous Operations
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Normalized Income
-19.75
-6.03%
-18.63
-39.92%
-13.32
+34.32%
-20.27
Net Income Common Stockholders
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Diluted EPS
-0.29
+99.50%
-58.50
+44.81%
-106.00
+63.29%
-288.75
Basic EPS
-0.29
+99.41%
-48.75
+54.01%
-106.00
+63.29%
-288.75
Basic Average Shares
77.80
+29192.80%
0.27
+111.41%
0.13
+79.45%
0.07
Diluted Average Shares
77.80
+25158.78%
0.31
+145.17%
0.13
+79.45%
0.07
Diluted NI Availto Com Stockholders
-22.39
-24.19%
-18.02
-35.36%
-13.32
+34.32%
-20.27
Average Dilution Earnings
0.00
+100.00%
-5.05
—
—
Gain On Sale Of PPE
—
—
—
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31
Total Assets
16.32
+146.12%
6.63
-41.75%
11.39
Current Assets
15.17
+188.46%
5.26
-46.52%
9.83
Cash Cash Equivalents And Short Term Investments
8.61
+138.82%
3.61
-57.84%
8.55
Cash And Cash Equivalents
4.26
+5500.00%
0.08
-99.11%
8.55
Other Short Term Investments
4.36
+23.40%
3.53
0.00
Receivables
0.32
-43.61%
0.57
0.00
Other Receivables
0.32
-43.61%
0.57
—
Prepaid Assets
1.34
+107.43%
0.65
-38.24%
1.05
Current Deferred Assets
0.39
-9.63%
0.44
+86.32%
0.23
Restricted Cash
4.50
0.00
—
Other Current Assets
—
—
—
Total Non Current Assets
1.16
-15.94%
1.37
-11.58%
1.55
Net PPE
0.33
-37.24%
0.52
-52.98%
1.11
Gross PPE
3.66
+0.03%
3.66
+0.47%
3.64
Accumulated Depreciation
-3.33
-6.21%
-3.14
-23.82%
-2.54
Properties
0.00
0.00
0.00
Machinery Furniture Equipment
1.78
+0.22%
1.78
+8.95%
1.63
Other Properties
0.07
-4.11%
0.07
-63.86%
0.20
Leases
1.81
+0.00%
1.81
+0.00%
1.81
Goodwill And Other Intangible Assets
0.70
-16.17%
0.84
+103.14%
0.41
Goodwill
0.37
+0.00%
0.37
+0.00%
0.37
Other Intangible Assets
0.33
-29.00%
0.47
+1016.67%
0.04
Other Non Current Assets
0.12
+925.00%
0.01
-62.50%
0.03
Total Liabilities Net Minority Interest
12.33
-20.88%
15.58
+22.35%
12.74
Current Liabilities
12.31
-20.82%
15.55
+44.97%
10.73
Payables And Accrued Expenses
5.50
-49.70%
10.93
+74.60%
6.26
Payables
3.28
-65.42%
9.47
+99.12%
4.76
Accounts Payable
3.28
-65.42%
9.47
+99.12%
4.76
Current Accrued Expenses
2.22
+52.47%
1.46
-2.99%
1.50
Pensionand Other Post Retirement Benefit Plans Current
0.42
+18.26%
0.36
-3.78%
0.37
Current Debt And Capital Lease Obligation
0.81
-75.84%
3.34
-18.55%
4.10
Current Debt
0.75
-77.22%
3.29
-17.20%
3.98
Other Current Borrowings
—
—
3.98
Current Capital Lease Obligation
0.06
+27.27%
0.04
-63.33%
0.12
Current Deferred Liabilities
0.93
+0.00%
0.93
0.00
Current Deferred Revenue
0.93
+0.00%
0.93
0.00
Other Current Liabilities
4.66
—
—
Total Non Current Liabilities Net Minority Interest
0.01
-51.61%
0.03
-98.46%
2.01
Long Term Debt And Capital Lease Obligation
0.01
-51.61%
0.03
-63.53%
0.09
Long Term Debt
—
—
—
Long Term Capital Lease Obligation
0.01
-51.61%
0.03
-63.53%
0.09
Non Current Deferred Liabilities
—
0.00
-100.00%
1.92
Non Current Deferred Revenue
—
0.00
-100.00%
1.92
Stockholders Equity
4.00
+144.65%
-8.95
-563.87%
-1.35
Common Stock Equity
4.00
+144.65%
-8.95
-563.87%
-1.35
Capital Stock
0.14
+2216.67%
0.01
+20.00%
0.01
Common Stock
0.14
+2216.67%
0.01
+20.00%
0.01
Preferred Stock
0.00
0.00
0.00
Share Issued
5.56
+2157.35%
0.25
+36.09%
0.18
Ordinary Shares Number
5.55
+2251.90%
0.24
+32.68%
0.18
Treasury Shares Number
0.01
+0.00%
0.01
+228.99%
0.00
Additional Paid In Capital
520.22
+7.26%
485.02
+1.20%
479.27
Retained Earnings
-515.87
-4.54%
-493.48
-2.70%
-480.50
Treasury Stock
0.50
+0.00%
0.50
+296.83%
0.13
Total Equity Gross Minority Interest
4.00
+144.65%
-8.95
-563.87%
-1.35
Total Capitalization
4.00
+144.65%
-8.95
-563.87%
-1.35
Working Capital
2.86
+127.75%
-10.29
-1052.52%
-0.89
Invested Capital
4.75
+183.90%
-5.66
-315.26%
2.63
Total Debt
0.82
-75.62%
3.37
-19.47%
4.18
Net Debt
—
3.22
—
Capital Lease Obligations
0.07
-5.33%
0.07
-63.41%
0.20
Net Tangible Assets
3.29
+133.62%
-9.79
-455.62%
-1.76
Tangible Book Value
3.29
+133.62%
-9.79
-455.62%
-1.76
Derivative Product Liabilities
—
—
—
Interest Payable
0.00
-100.00%
0.12
0.00
Line Of Credit
0.75
-77.22%
3.29
-17.20%
3.98
Preferred Shares Number
0.00
+0.00%
0.00
+0.00%
0.00
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-20.77
-96.84%
-10.55
+17.87%
-12.85
+0.93%
-12.97
Cash Flow From Continuing Operating Activities
-20.77
-96.84%
-10.55
+17.87%
-12.85
+0.93%
-12.97
Net Income From Continuing Operations
-22.39
-72.49%
-12.98
+2.54%
-13.32
+34.32%
-20.27
Depreciation Amortization Depletion
0.45
-48.97%
0.87
+38.85%
0.63
+1.45%
0.62
Depreciation
—
0.60
+0.00%
0.60
+20.00%
0.50
Amortization Cash Flow
—
0.10
+0.00%
0.10
+0.00%
0.10
Depreciation And Amortization
0.45
-48.97%
0.87
+38.85%
0.63
+1.45%
0.62
Amortization Of Intangibles
—
0.10
+0.00%
0.10
+0.00%
0.10
Other Non Cash Items
3.06
-13.65%
3.54
+828.01%
0.38
-1.55%
0.39
Stock Based Compensation
1.54
+180.00%
0.55
-3.34%
0.57
-6.11%
0.61
Asset Impairment Charge
—
—
0.12
+25.81%
0.09
Operating Gains Losses
2.62
+146.25%
-5.65
-282800.00%
0.00
—
Gain Loss On Investment Securities
2.63
+146.53%
-5.65
—
—
Unrealized Gain Loss On Investment Securities
—
—
—
-0.00
Gain Loss On Sale Of PPE
—
0.00
-100.00%
0.00
0.00
Change In Working Capital
-6.04
-287.49%
3.22
+388.71%
-1.12
-119.94%
5.60
Change In Receivables
0.25
+143.61%
-0.57
0.00
—
Changes In Account Receivables
—
—
—
—
Change In Payables And Accrued Expense
-5.62
-219.52%
4.70
+227.88%
-3.68
-156.99%
6.45
Change In Other Working Capital
—
-1.00
-454.80%
0.28
-82.90%
1.64
Change In Other Current Assets
-0.76
-450.00%
0.22
-90.91%
2.40
+201.18%
-2.37
Change In Other Current Liabilities
0.09
+171.54%
-0.13
-11.11%
-0.12
+9.30%
-0.13
Investing Cash Flow
-0.85
+79.23%
-4.11
-2469.38%
-0.16
+78.92%
-0.76
Cash Flow From Continuing Investing Activities
-0.85
+79.23%
-4.11
-2469.38%
-0.16
+78.92%
-0.76
Net PPE Purchase And Sale
-0.04
+74.66%
-0.15
+8.75%
-0.16
+68.57%
-0.51
Purchase Of PPE
-0.07
+54.11%
-0.15
+8.75%
-0.16
+68.57%
-0.51
Sale Of PPE
0.03
0.00
—
0.00
Capital Expenditure
-0.07
+90.30%
-0.69
-331.88%
-0.16
+78.92%
-0.76
Net Investment Purchase And Sale
-0.82
+76.11%
-3.42
0.00
—
Purchase Of Investment
-9.35
+40.01%
-15.59
0.00
—
Sale Of Investment
8.54
-29.86%
12.17
0.00
—
Net Intangibles Purchase And Sale
0.00
+100.00%
-0.55
0.00
+100.00%
-0.25
Purchase Of Intangibles
0.00
+100.00%
-0.55
0.00
+100.00%
-0.25
Net Other Investing Changes
—
—
—
-0.25
Financing Cash Flow
30.31
+389.91%
6.19
+79.59%
3.44
-74.39%
13.45
Cash Flow From Continuing Financing Activities
30.31
+389.91%
6.19
+79.59%
3.44
-74.39%
13.45
Net Issuance Payments Of Debt
-2.51
-256.11%
-0.70
+56.22%
-1.61
+0.00%
-1.61
Issuance Of Debt
4.49
+36.33%
3.29
0.00
—
Repayment Of Debt
-7.00
-75.05%
-4.00
-148.51%
-1.61
+0.00%
-1.61
Long Term Debt Issuance
3.74
0.00
—
—
Long Term Debt Payments
-3.70
+7.33%
-4.00
-148.51%
-1.61
+0.00%
-1.61
Net Long Term Debt Issuance
0.04
+100.88%
-4.00
-148.51%
-1.61
+0.00%
-1.61
Short Term Debt Issuance
0.75
-77.22%
3.29
0.00
—
Short Term Debt Payments
-3.29
0.00
—
—
Net Short Term Debt Issuance
-2.54
-177.22%
3.29
0.00
—
Net Common Stock Issuance
38.54
+459.29%
6.89
+27.59%
5.40
-65.89%
15.83
Common Stock Payments
0.00
+100.00%
-0.37
-196.83%
-0.13
0.00
Repurchase Of Capital Stock
0.00
+100.00%
-0.37
-196.83%
-0.13
0.00
Proceeds From Stock Option Exercised
—
—
—
0.00
Net Other Financing Charges
-5.72
—
-0.35
+54.98%
-0.77
Changes In Cash
8.68
+202.41%
-8.48
+11.37%
-9.57
-3316.43%
-0.28
Beginning Cash Position
0.08
-99.11%
8.55
-52.79%
18.12
-1.52%
18.40
End Cash Position
8.76
+11423.68%
0.08
-99.11%
8.55
-52.79%
18.12
Free Cash Flow
-20.84
-85.34%
-11.24
+13.57%
-13.01
+5.24%
-13.73
Interest Paid Supplemental Data
0.00
-100.00%
0.03
-85.59%
0.22
-32.11%
0.33
Amortization Of Securities
-0.01
+91.89%
-0.11
0.00
—
Common Stock Issuance
38.54
+430.50%
7.26
+31.45%
5.53
-65.09%
15.83
Issuance Of Capital Stock
38.54
+430.50%
7.26
+31.45%
5.53
-65.09%
15.83
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Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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