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About

Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline consist of UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SC291, a HIP-modified allogeneic CD19-dirtected allogeneic CAR T cell product candidate which is in phase 1 clinical trial to treat systemic lupus erythematosus and ANCA-associated vasculitis, as well as in preclinical trial to treat other indications and b-cell mediated autoimmune disease; and SG299, a CD8-targeted fusosome, which is in preclinical trial to treat patients with hematologic malignancies and B cell mediated autoimmune diseases. It also develops SC262, a hypoimmune-modified CD22-directed allogeneic CAR T program, which is in phase 1 to treat non-Hodgkin's lymphoma; and SG299, a CD8-targeted fusosome, which is in preclinical trial to treat patients with hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.

Fundamentals
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Sector Healthcare Industry Biotechnology Market Cap 1.13B
Enterprise Value 1.06B Income -234.41M Sales —
Book/sh 0.74 Cash/sh 0.57 Dividend Yield —
Payout 0.00% Employees 194 IPO —
P/E — Forward P/E -7.47 PEG —
P/S — P/B 5.68 P/C —
EV/EBITDA -6.02 EV/Sales — Quick Ratio 4.31
Current Ratio 4.55 Debt/Eq 45.95 LT Debt/Eq —
EPS (ttm) -0.96 EPS next Y -0.57 EPS Growth —
Revenue Growth — Earnings 2026-03-16 ROA -23.90%
ROE -96.11% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 266.37M
Shs Float 176.96M Short Float 37.76% Short Ratio 14.61
Short Interest — 52W High 6.55 52W Low 1.26
Beta 1.97 Avg Volume 3.52M Volume 1.35M
Target Price $8.71 Recom Strong_buy Prev Close $4.07
Price $4.23 Change 3.93%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$8.71
Mean price target
2. Current target
$4.23
Latest analyst target
3. DCF / Fair value
$-6.32
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$4.23
Low
$6.00
High
$12.00
Mean
$8.71

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-06 main B of A Securities Buy → Buy $7
2025-11-07 main Wedbush Outperform → Outperform $6
2025-11-07 main HC Wainwright & Co. Buy → Buy $9
2025-10-30 main Citizens Market Outperform → Market Outperform $8
2025-09-24 init Wedbush — → Outperform $5
2025-06-24 reit JMP Securities Market Outperform → Market Outperform $5
2025-04-24 reit HC Wainwright & Co. Buy → Buy $11
2025-03-18 up Citizens Capital Markets Market Perform → Market Outperform $5
2025-03-18 reit HC Wainwright & Co. Buy → Buy $11
2025-03-14 init Jefferies — → Buy $7
2025-01-08 main HC Wainwright & Co. Buy → Buy $11
2025-01-08 up TD Cowen Hold → Buy —
2024-11-27 reit HC Wainwright & Co. Buy → Buy $8
2024-11-11 reit HC Wainwright & Co. Buy → Buy $8
2024-11-05 main HC Wainwright & Co. Buy → Buy $8
2024-11-05 down JMP Securities Market Outperform → Market Perform —
2024-08-09 main Citigroup Buy → Buy $15
2024-08-09 main HC Wainwright & Co. Buy → Buy $11
2024-05-09 reit HC Wainwright & Co. Buy → Buy $12
2024-03-01 main JMP Securities Market Outperform → Market Outperform $15
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 6157 — — Stock Award(Grant) at price 0.00 per share. BISHOP HANS EDGAR Director — 2026-01-05 00:00:00 D
1 7500 nan — — WYRICK SUSAN D Chief Financial Officer — 2026-01-02 00:00:00 D
2 3400 nan — — WYRICK SUSAN D Chief Financial Officer — 2025-12-12 00:00:00 D
3 20000 nan — — WYRICK SUSAN D Chief Financial Officer — 2025-12-03 00:00:00 D
4 5628 — — Stock Award(Grant) at price 0.00 per share. BISHOP HANS EDGAR Director — 2025-10-06 00:00:00 D
5 7842 — — Stock Award(Grant) at price 0.00 per share. BISHOP HANS EDGAR Director — 2025-07-07 00:00:00 D
6 16339 — — Stock Award(Grant) at price 0.00 per share. BISHOP HANS EDGAR Director — 2025-04-07 00:00:00 D
7 11041 nan — — CASSIDY BERNARD J General Counsel — 2025-03-07 00:00:00 D
8 3250 nan — — WYRICK SUSAN D Chief Financial Officer — 2025-03-07 00:00:00 D
9 50000 nan — — HARR STEVEN D Chief Executive Officer — 2025-03-07 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-255.33M-268.58M-256.94M-345.84M
NetIncomeFromContinuingOperationNetMinorityInterest-266.76M-283.25M-269.48M-355.93M
ReconciledDepreciation17.39M24.56M15.62M11.07M
EBITDA-255.33M-268.58M-256.94M-345.84M
EBIT-272.72M-293.14M-272.56M-356.91M
NetInterestIncome10.47M9.94M3.76M676.00K
InterestIncome10.47M9.94M3.76M676.00K
NormalizedIncome-266.76M-283.25M-269.48M-355.93M
NetIncomeFromContinuingAndDiscontinuedOperation-266.76M-283.25M-269.48M-355.93M
TotalExpenses272.72M293.14M272.56M356.91M
TotalOperatingIncomeAsReported-272.72M-293.14M-272.56M-356.91M
DilutedAverageShares230.89M194.54M188.34M166.43M
BasicAverageShares230.89M194.54M188.34M166.43M
DilutedEPS-1.16-1.46-1.43-2.14
BasicEPS-1.16-1.46-1.43-2.14
DilutedNIAvailtoComStockholders-266.76M-283.25M-269.48M-355.93M
NetIncomeCommonStockholders-266.76M-283.25M-269.48M-355.93M
NetIncome-266.76M-283.25M-269.48M-355.93M
NetIncomeIncludingNoncontrollingInterests-266.76M-283.25M-269.48M-355.93M
NetIncomeContinuousOperations-266.76M-283.25M-269.48M-355.93M
TaxProvision0.00
PretaxIncome-266.76M-283.25M-269.48M-355.93M
OtherIncomeExpense-4.51M-52.00K-674.00K305.00K
OtherNonOperatingIncomeExpenses-4.51M-52.00K-674.00K305.00K
NetNonOperatingInterestIncomeExpense10.47M9.94M3.76M676.00K
InterestIncomeNonOperating10.47M9.94M3.76M676.00K
OperatingIncome-272.72M-293.14M-272.56M-356.91M
OperatingExpense272.72M293.14M272.56M356.91M
ResearchAndDevelopment208.68M219.84M201.00M306.50M
SellingGeneralAndAdministration64.04M73.30M71.56M50.41M
GeneralAndAdministrativeExpense64.04M73.30M71.56M50.41M
OtherGandA64.04M73.30M71.56M50.41M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2024-12-312023-12-312022-12-312021-12-31
OrdinarySharesNumber223.92M197.86M191.02M184.93M
ShareIssued223.92M197.86M191.02M184.93M
TotalDebt94.20M104.10M108.25M110.94M
TangibleBookValue50.68M87.68M299.49M528.68M
InvestedCapital250.50M287.51M499.31M728.50M
WorkingCapital115.38M149.03M332.93M458.87M
NetTangibleAssets50.68M87.68M299.49M528.68M
CapitalLeaseObligations94.20M104.10M108.25M110.94M
CommonStockEquity250.50M287.51M499.31M728.50M
TotalCapitalization250.50M287.51M499.31M728.50M
TotalEquityGrossMinorityInterest250.50M287.51M499.31M728.50M
StockholdersEquity250.50M287.51M499.31M728.50M
GainsLossesNotAffectingRetainedEarnings14.00K-60.00K-4.33M-1.37M
OtherEquityAdjustments14.00K-60.00K-4.33M-1.37M
RetainedEarnings-1.60B-1.34B-1.05B-785.36M
AdditionalPaidInCapital1.86B1.63B1.56B1.52B
CapitalStock22.00K20.00K19.00K18.00K
CommonStock22.00K20.00K19.00K18.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest250.52M277.79M323.40M400.90M
TotalNonCurrentLiabilitiesNetMinorityInterest205.08M213.31M211.90M301.67M
OtherNonCurrentLiabilities123.42M122.41M116.04M199.89M
LongTermDebtAndCapitalLeaseObligation81.66M90.90M95.86M101.78M
LongTermCapitalLeaseObligation81.66M90.90M95.86M101.78M
CurrentLiabilities45.43M64.49M111.50M99.23M
OtherCurrentLiabilities55.34M56.38M
CurrentDebtAndCapitalLeaseObligation12.53M13.20M12.39M9.16M
CurrentCapitalLeaseObligation12.53M13.20M12.39M9.16M
PensionandOtherPostRetirementBenefitPlansCurrent11.43M19.79M21.25M18.24M
PayablesAndAccruedExpenses21.47M31.51M22.52M15.45M
CurrentAccruedExpenses16.26M27.40M19.66M13.23M
Payables5.21M4.11M2.86M2.22M
AccountsPayable5.21M4.11M2.86M2.22M
TotalAssets501.02M565.30M822.72M1.13B
TotalNonCurrentAssets340.21M351.78M378.28M571.31M
OtherNonCurrentAssets5.12M6.37M9.01M13.82M
InvestmentsAndAdvances0.0010.05M195.88M
InvestmentinFinancialAssets0.0010.05M195.88M
AvailableForSaleSecurities10.05M195.88M
GoodwillAndOtherIntangibleAssets199.82M199.82M199.82M199.82M
OtherIntangibleAssets59.20M59.20M59.20M59.20M
Goodwill140.63M140.63M140.63M140.63M
NetPPE135.27M145.59M159.40M161.78M
AccumulatedDepreciation-54.17M-41.77M-33.98M-18.77M
GrossPPE189.44M187.36M193.38M180.56M
Leases33.34M31.36M34.43M33.85M
ConstructionInProgress40.34M26.33M1.71M1.39M
OtherProperties110.92M126.55M154.33M144.00M
MachineryFurnitureEquipment4.84M3.12M2.91M1.32M
Properties0.000.000.000.00
CurrentAssets160.81M213.51M444.44M558.10M
OtherCurrentAssets4.48M4.49M14.37M7.11M
RestrictedCash3.83M3.83M6.10M0.00
PrepaidAssets7.11M
CashCashEquivalentsAndShortTermInvestments152.50M205.19M423.96M551.00M
OtherShortTermInvestments24.93M71.68M247.20M297.97M
CashAndCashEquivalents127.57M133.52M176.76M253.03M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-256.58M-273.61M-310.93M-280.92M
IssuanceOfDebt7.74M0.000.00
IssuanceOfCapitalStock181.00M27.02M601.00K631.75M
CapitalExpenditure-33.43M-20.03M-20.88M-29.86M
EndCashPosition131.40M137.35M187.27M261.85M
BeginningCashPosition137.35M187.27M261.85M126.95M
ChangesInCash-5.95M-49.92M-74.58M134.90M
FinancingCashFlow199.75M31.65M4.91M631.75M
CashFlowFromContinuingFinancingActivities199.75M31.65M4.91M631.75M
ProceedsFromStockOptionExercised11.01M4.63M4.31M5.35M
NetPreferredStockIssuance0.000.00
PreferredStockIssuance0.000.00
NetCommonStockIssuance181.00M27.02M601.00K631.75M
CommonStockIssuance181.00M27.02M601.00K631.75M
NetIssuancePaymentsOfDebt7.74M0.000.00
NetLongTermDebtIssuance7.74M0.000.00
LongTermDebtIssuance7.74M0.000.00
InvestingCashFlow17.45M172.01M210.56M-245.80M
CashFlowFromContinuingInvestingActivities17.45M172.01M210.56M-245.80M
NetOtherInvestingChanges-4.57M
NetInvestmentPurchaseAndSale50.88M192.04M231.44M-211.36M
SaleOfInvestment276.95M349.79M310.13M280.02M
PurchaseOfInvestment-226.06M-157.74M-78.69M-491.39M
NetBusinessPurchaseAndSale0.00
PurchaseOfBusiness0.00
NetPPEPurchaseAndSale-33.43M-20.03M-20.88M-29.86M
PurchaseOfPPE-33.43M-20.03M-20.88M-29.86M
OperatingCashFlow-223.15M-253.58M-290.05M-251.05M
CashFlowFromContinuingOperatingActivities-223.15M-253.58M-290.05M-251.05M
ChangeInWorkingCapital-1.19M18.61M7.54M9.80M
ChangeInOtherWorkingCapital9.34M10.96M1.56M5.09M
ChangeInPayablesAndAccruedExpense-7.01M-491.00K11.97M5.57M
ChangeInAccruedExpense-8.39M-1.52M10.91M5.84M
ChangeInPayable1.38M1.03M1.06M-266.00K
ChangeInAccountPayable1.38M1.03M1.06M-266.00K
ChangeInPrepaidAssets-3.51M8.14M-5.99M-861.00K
OtherNonCashItems-10.28M-49.03M-82.08M61.64M
StockBasedCompensation37.68M35.53M38.34M22.36M
DeferredTax0.00
DeferredIncomeTax0.00
DepreciationAmortizationDepletion17.39M24.56M15.62M11.07M
DepreciationAndAmortization17.39M24.56M15.62M11.07M
Depreciation17.39M24.56M15.62M11.07M
NetIncomeFromContinuingOperations-266.76M-283.25M-269.48M-355.93M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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