Symbols / SHPH
SHPH Chart
About
Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.
Fundamentals
Scroll to Statements| Sector | Healthcare | Industry | Drug Manufacturers - Spe | Market Cap | 3.51M |
| Enterprise Value | 256.14K | Income | -10.71M | Sales | — |
| Book/sh | 1.13 | Cash/sh | 1.31 | Dividend Yield | — |
| Payout | 0.00% | Employees | 9 | IPO | — |
| P/E | — | Forward P/E | — | PEG | — |
| P/S | — | P/B | 0.96 | P/C | — |
| EV/EBITDA | -0.02 | EV/Sales | — | Quick Ratio | 1.07 |
| Current Ratio | 1.66 | Debt/Eq | 47.87 | LT Debt/Eq | — |
| EPS (ttm) | -3.42 | EPS next Y | — | EPS Growth | — |
| Revenue Growth | — | Earnings | — | ROA | -3.23% |
| ROE | -271.76% | ROIC | — | Gross Margin | 0.00% |
| Oper. Margin | 0.00% | Profit Margin | 0.00% | Shs Outstand | 3.25M |
| Shs Float | 1.59M | Short Float | 23.32% | Short Ratio | 0.09 |
| Short Interest | — | 52W High | 16.90 | 52W Low | 1.00 |
| Beta | 0.46 | Avg Volume | 2.68M | Volume | 25.14K |
| Target Price | — | Recom | None | Prev Close | $1.05 |
| Price | $1.08 | Change | 2.86% |
Valuation Models
Price estimates from analyst targets and simple models.
1. Analyst consensus
—
Mean price target
2. Current target
$1.07
Latest analyst target
3. DCF / Fair value
$-38.14
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.07
Low
—
High
—
Mean
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- Shuttle Pharma (NASDAQ: SHPH) to issue 625,156-share pre-funded warrant; $2.5M placement - Stock Titan Mon, 03 Nov 2025 08
- Why Shuttle Pharmaceuticals (SHPH) Stock Surged Overnight? - Benzinga Fri, 21 Nov 2025 08
- Shuttle Pharmaceuticals stock soars after AI acquisition letter of intent - Investing.com hu, 09 Oct 2025 07
- Why Does SHPH Stock Dip? - StocksToTrade Fri, 21 Nov 2025 08
- Utah lets AI refill meds—and how a drug discovery platform fits this shift - Stock Titan ue, 13 Jan 2026 08
- Shuttle Pharma Rockets Over 100% As AI Drug Discovery Gains Attention - Nasdaq ue, 20 Jan 2026 08
- SHPH Stock Surge: AI Acquisition in Focus - timothysykes.com Fri, 21 Nov 2025 08
- Shuttle Pharmaceuticals CFO Resigns, Interim CEO Steps In - The Globe and Mail Sat, 29 Nov 2025 08
- Shuttle Pharmaceuticals stock falls after closing Molecule.ai acquisition - Investing.com Fri, 21 Nov 2025 08
- Shuttle Pharmaceuticals says reverse stock split to become effective June 16 - Yahoo Finance Fri, 13 Jun 2025 07
- Shuttle Pharmaceuticals (NASDAQ: SHPH) closes $8M Molecule.ai deal with $2M earnout - Stock Titan Fri, 21 Nov 2025 08
- What Does the Market Think About Shuttle Pharmaceuticals Holdings Inc? - Benzinga Wed, 21 Jan 2026 08
- Shuttle Pharma secures $2.5 million in above-market financing deal - Investing.com Mon, 03 Nov 2025 08
- Shuttle Pharma (NASDAQ: SHPH) signs LOI to acquire Molecule.ai for $10M in cash and stock - Stock Titan Wed, 22 Oct 2025 07
- Shuttle Pharmaceuticals stock surges on AI acquisition plans - Investing.com ue, 21 Oct 2025 07
Insider Transactions
| Date | Shares | Url | Text | Insider | Position | Transaction | Start Date | Ownership |
|---|---|---|---|---|---|---|---|---|
| 0 | 209790 | — | — | SCHAFER JOSHUA | Director | — | 2024-12-31 00:00:00 | D |
| 1 | 209790 | — | — | RICHARDS STEVEN M | Director | — | 2024-12-31 00:00:00 | D |
| 2 | 209790 | — | — | SCHAFER JOSHUA | Director | — | 2024-12-23 00:00:00 | D |
| 3 | 209790 | — | — | RICHARDS STEVEN M | Director | — | 2024-12-23 00:00:00 | D |
| 4 | 209790 | — | — | BROWN MILTON | Director | — | 2024-12-23 00:00:00 | D |
| 5 | 100000 | — | — | VANDER HOEK MICHAEL | Chief Financial Officer | — | 2024-03-08 00:00:00 | D |
Financials
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|
| TaxEffectOfUnusualItems | 0.00 | 0.00 | 0.00 | 0.00 |
| TaxRateForCalcs | 0.00 | 0.00 | 0.00 | 0.00 |
| NormalizedEBITDA | -7.53M | -5.81M | -2.53M | -1.68M |
| TotalUnusualItems | -249.16K | 1.82M | -1.98M | 641.65K |
| TotalUnusualItemsExcludingGoodwill | -249.16K | 1.82M | -1.98M | 641.65K |
| NetIncomeFromContinuingOperationNetMinorityInterest | -9.14M | -6.59M | -5.00M | -1.15M |
| ReconciledDepreciation | 5.46K | 6.81K | 5.97K | 60.83K |
| EBITDA | -7.78M | -3.99M | -4.51M | -1.04M |
| EBIT | -7.78M | -4.00M | -4.52M | -1.10M |
| NetInterestIncome | -1.32M | -2.52M | -670.61K | -50.79K |
| InterestExpense | 1.36M | 2.60M | 480.70K | 50.79K |
| InterestIncome | 38.14K | 79.12K | 0.00 | |
| NormalizedIncome | -8.90M | -8.41M | -3.01M | -1.79M |
| NetIncomeFromContinuingAndDiscontinuedOperation | -9.14M | -6.59M | -5.00M | -1.15M |
| TotalExpenses | 7.70M | 5.89M | 2.34M | 1.74M |
| TotalOperatingIncomeAsReported | -7.70M | -5.89M | -2.34M | -1.74M |
| DilutedAverageShares | 115.49K | 74.65K | 53.51K | 66.42K |
| BasicAverageShares | 114.80K | 74.65K | 53.51K | 66.42K |
| DilutedEPS | -82.50 | -88.25 | -126.00 | -18.90 |
| BasicEPS | -79.75 | -88.25 | -126.00 | -18.90 |
| DilutedNIAvailtoComStockholders | -9.14M | -6.59M | -6.75M | -1.26M |
| NetIncomeCommonStockholders | -9.14M | -6.59M | -6.75M | -1.26M |
| OtherunderPreferredStockDividend | 0.00 | 941.00K | ||
| PreferredStockDividends | 810.07K | 103.06K | ||
| NetIncome | -9.14M | -6.59M | -5.00M | -1.15M |
| NetIncomeIncludingNoncontrollingInterests | -9.14M | -6.59M | -5.00M | -1.15M |
| NetIncomeContinuousOperations | -9.14M | -6.59M | -5.00M | -1.15M |
| TaxProvision | 0.00 | 0.00 | ||
| PretaxIncome | -9.14M | -6.59M | -5.00M | -1.15M |
| OtherIncomeExpense | -126.61K | 1.82M | -1.98M | 641.65K |
| OtherNonOperatingIncomeExpenses | 122.55K | 328.69K | ||
| SpecialIncomeCharges | -833.50K | -477.22K | -1.39M | 62.50K |
| OtherSpecialCharges | 833.50K | 477.22K | 1.39M | -62.50K |
| WriteOff | 0.00 | |||
| GainOnSaleOfSecurity | 584.34K | 2.29M | -587.67K | 579.15K |
| NetNonOperatingInterestIncomeExpense | -1.32M | -2.52M | -670.61K | -50.79K |
| TotalOtherFinanceCost | 104.25K | 189.91K | ||
| InterestExpenseNonOperating | 1.36M | 2.60M | 480.70K | 50.79K |
| InterestIncomeNonOperating | 38.14K | 79.12K | 0.00 | |
| OperatingIncome | -7.70M | -5.89M | -2.34M | -1.74M |
| OperatingExpense | 7.70M | 5.89M | 2.34M | 1.74M |
| ResearchAndDevelopment | 3.62M | 3.52M | 1.05M | 1.02M |
| SellingGeneralAndAdministration | 4.08M | 2.38M | 1.30M | 721.18K |
| GeneralAndAdministrativeExpense | 4.08M | 2.38M | 1.30M | 721.18K |
| OtherGandA | 4.08M | 2.38M | 1.30M | 721.18K |
| TotalRevenue | 0.00 | 0.00 | 0.00 | 0.00 |
| OperatingRevenue | 0.00 | 0.00 | 0.00 | 0.00 |
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|
| OrdinarySharesNumber | 163.06K | 80.35K | 68.02K | 66.42K |
| ShareIssued | 163.06K | 80.35K | 68.02K | 66.42K |
| NetDebt | 344.75K | |||
| TotalDebt | 1.17M | 1.09M | 748.30K | 978.88K |
| TangibleBookValue | 709.15K | 4.06M | 7.68M | -1.63M |
| InvestedCapital | 1.58M | 4.79M | 8.36M | -778.63K |
| WorkingCapital | 677.15K | 4.55M | 7.60M | -1.71M |
| NetTangibleAssets | 709.15K | 4.06M | 7.68M | -1.63M |
| CapitalLeaseObligations | 299.00K | 356.61K | 62.82K | 129.38K |
| CommonStockEquity | 709.15K | 4.06M | 7.68M | -1.63M |
| TotalCapitalization | 709.15K | 4.19M | 7.68M | -1.63M |
| TotalEquityGrossMinorityInterest | 709.15K | 4.06M | 7.68M | -1.63M |
| StockholdersEquity | 709.15K | 4.06M | 7.68M | -1.63M |
| OtherEquityInterest | 16.34K | |||
| RetainedEarnings | -34.58M | -25.43M | -18.84M | -5.80M |
| AdditionalPaidInCapital | 35.29M | 29.49M | 26.52M | 4.15M |
| CapitalStock | 41.00 | 20.00 | 17.00 | 93.00 |
| CommonStock | 41.00 | 20.00 | 17.00 | 93.00 |
| PreferredStock | 0.00 | 0.00 | 0.00 | 0.00 |
| TotalLiabilitiesNetMinorityInterest | 1.80M | 1.90M | 975.68K | 2.28M |
| TotalNonCurrentLiabilitiesNetMinorityInterest | 263.37K | 853.73K | 0.00 | 62.44K |
| DerivativeProductLiabilities | 25.28K | 414.51K | 0.00 | |
| LongTermDebtAndCapitalLeaseObligation | 238.09K | 439.22K | 0.00 | 62.44K |
| LongTermCapitalLeaseObligation | 238.09K | 304.13K | 0.00 | 62.44K |
| LongTermDebt | 135.09K | |||
| CurrentLiabilities | 1.53M | 1.04M | 975.68K | 2.22M |
| OtherCurrentLiabilities | 94.03K | |||
| CurrentDebtAndCapitalLeaseObligation | 935.38K | 648.48K | 748.30K | 916.43K |
| CurrentCapitalLeaseObligation | 60.91K | 52.48K | 62.82K | 66.93K |
| CurrentDebt | 874.48K | 596.00K | 685.47K | 849.50K |
| OtherCurrentBorrowings | 684.21K | 596.00K | ||
| CurrentNotesPayable | 190.27K | 0.00 | 685.47K | 849.50K |
| PayablesAndAccruedExpenses | 598.38K | 393.76K | 227.38K | 1.21M |
| CurrentAccruedExpenses | 1.78K | 110.45K | 98.14K | 47.50K |
| InterestPayable | 1.78K | 110.45K | 98.14K | 47.50K |
| Payables | 596.60K | 283.31K | 129.25K | 1.16M |
| DividendsPayable | 0.00 | 331.06K | ||
| AccountsPayable | 596.60K | 283.31K | 129.25K | 828.31K |
| TotalAssets | 2.51M | 5.95M | 8.65M | 651.64K |
| TotalNonCurrentAssets | 295.37K | 358.73K | 75.19K | 142.03K |
| OtherNonCurrentAssets | 6.48K | 6.48K | ||
| NetPPE | 295.37K | 358.73K | 68.71K | 135.55K |
| AccumulatedDepreciation | -121.69K | -114.88K | -257.13K | |
| GrossPPE | 295.37K | 358.73K | 183.59K | 392.67K |
| OtherProperties | 295.37K | 358.73K | 183.59K | 383.81K |
| MachineryFurnitureEquipment | 8.86K | 8.86K | ||
| CurrentAssets | 2.21M | 5.59M | 8.58M | 509.62K |
| PrepaidAssets | 290.77K | 114.47K | 161.15K | 4.87K |
| Receivables | 0.00 | 14.90K | 0.00 | 0.00 |
| AccruedInterestReceivable | 0.00 | 14.90K | 0.00 | |
| AccountsReceivable | 0.00 | |||
| CashCashEquivalentsAndShortTermInvestments | 1.92M | 5.46M | 8.42M | 504.75K |
| OtherShortTermInvestments | 0.00 | 2.89M | 0.00 | |
| CashAndCashEquivalents | 1.92M | 2.58M | 8.42M | 504.75K |
| CashEquivalents | 1.20K | 1.03M | 3.01M | |
| CashFinancial | 1.92M | 1.55M | 5.41M | 504.75K |
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|
| FreeCashFlow | -7.33M | -5.60M | -2.67M | -300.34K |
| RepaymentOfDebt | -906.54K | -685.47K | -50.00K | 0.00 |
| IssuanceOfDebt | 1.04M | 3.94M | 650.72K | 687.93K |
| IssuanceOfCapitalStock | 3.99M | 0.00 | 10.00M | 0.00 |
| CapitalExpenditure | -19.05K | |||
| InterestPaidSupplementalData | 86.59K | 164.81K | 39.20K | 293.00 |
| IncomeTaxPaidSupplementalData | 0.00 | 0.00 | 0.00 | 0.00 |
| EndCashPosition | 1.92M | 2.58M | 8.42M | 504.75K |
| BeginningCashPosition | 2.58M | 8.42M | 504.75K | 117.15K |
| ChangesInCash | -656.27K | -5.84M | 7.91M | 387.60K |
| FinancingCashFlow | 3.76M | 2.57M | 10.58M | 687.93K |
| CashFlowFromContinuingFinancingActivities | 3.76M | 2.57M | 10.58M | 687.93K |
| NetOtherFinancingCharges | -371.68K | -334.44K | -17.36K | |
| ProceedsFromStockOptionExercised | 729.00 | -345.00K | ||
| NetCommonStockIssuance | 3.99M | 0.00 | 10.00M | 0.00 |
| CommonStockIssuance | 3.99M | 0.00 | 10.00M | 0.00 |
| NetIssuancePaymentsOfDebt | 133.46K | 3.25M | 600.72K | 687.93K |
| NetShortTermDebtIssuance | 190.27K | -685.47K | 0.00 | 687.93K |
| ShortTermDebtPayments | -59.73K | -685.47K | -50.00K | 0.00 |
| ShortTermDebtIssuance | 250.00K | 0.00 | 50.00K | 687.93K |
| NetLongTermDebtIssuance | -56.81K | 3.94M | 600.72K | |
| LongTermDebtPayments | -846.81K | 0.00 | 0.00 | |
| LongTermDebtIssuance | 790.00K | 3.94M | 600.72K | |
| InvestingCashFlow | 2.92M | -2.83M | 0.00 | 0.00 |
| CashFlowFromContinuingInvestingActivities | 2.92M | -2.83M | 0.00 | 0.00 |
| NetInvestmentPurchaseAndSale | 2.92M | -2.81M | 0.00 | |
| SaleOfInvestment | 2.96M | 187.90K | 0.00 | |
| PurchaseOfInvestment | -43.59K | -3.00M | 0.00 | |
| NetPPEPurchaseAndSale | 0.00 | -19.05K | 0.00 | 0.00 |
| PurchaseOfPPE | 0.00 | -19.05K | 0.00 | 0.00 |
| OperatingCashFlow | -7.33M | -5.58M | -2.67M | -300.34K |
| CashFlowFromContinuingOperatingActivities | -7.33M | -5.58M | -2.67M | -300.34K |
| ChangeInWorkingCapital | 138.91K | 220.63K | -462.79K | 519.15K |
| ChangeInOtherWorkingCapital | 286.00 | 16.00K | -5.69K | |
| ChangeInOtherCurrentLiabilities | -66.55K | -58.47K | ||
| ChangeInOtherCurrentAssets | 0.00 | 6.48K | 0.00 | |
| ChangeInPayablesAndAccruedExpense | 300.02K | 166.38K | -300.81K | 358.45K |
| ChangeInAccruedExpense | -13.27K | 12.32K | 69.57K | 47.11K |
| ChangeInInterestPayable | -13.27K | 12.32K | 69.57K | 47.11K |
| ChangeInPayable | 313.30K | 154.06K | -370.38K | 311.35K |
| ChangeInAccountPayable | 313.30K | 154.06K | -370.38K | 311.35K |
| ChangeInPrepaidAssets | -176.30K | 46.67K | -156.28K | 7.71K |
| ChangeInReceivables | 14.90K | -14.90K | 0.00 | 211.46K |
| ChangesInAccountReceivables | 0.00 | 211.46K | ||
| OtherNonCashItems | 1.29M | 2.42M | -24.31K | 3.39K |
| StockBasedCompensation | 259.74K | 181.96K | 237.55K | 910.07K |
| UnrealizedGainLossOnInvestmentSecurities | -122.55K | -71.57K | 0.00 | |
| DepreciationAmortizationDepletion | 5.46K | 6.81K | 5.97K | 60.83K |
| DepreciationAndAmortization | 5.46K | 6.81K | 5.97K | 60.83K |
| Depreciation | 5.46K | 6.81K | 5.97K | 60.83K |
| OperatingGainsLosses | 249.16K | -1.74M | 2.57M | -641.65K |
| GainLossOnInvestmentSecurities | -584.34K | -2.22M | 777.59K | -579.15K |
| NetIncomeFromContinuingOperations | -9.14M | -6.59M | -5.00M | -1.15M |
SEC Filings
Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.
Public Trades for SHPH
| Date | User | Asset | Broker | Type | Position Size | Entry Price | Patterns |
|---|