Symbols / SHPH $0.76 +12.86% Shuttle Pharmaceuticals Holdings, Inc.

Healthcare • Drug Manufacturers - Specialty & Generic • United States • NCM
SHPH Chart
About

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Drug Manufacturers - Spe Market Cap 4.24M
Enterprise Value 4.14M Income -11.72M Sales —
Book/sh 1.13 Cash/sh 0.06 Dividend Yield —
Payout 0.00% Employees — IPO —
P/E — Forward P/E — PEG —
P/S — P/B 0.67 P/C —
EV/EBITDA -0.36 EV/Sales — Quick Ratio 0.04
Current Ratio 0.06 Debt/Eq 10.30 LT Debt/Eq —
EPS (ttm) -7.16 EPS next Y — EPS Growth —
Revenue Growth — Earnings — ROA -114.74%
ROE -7.91% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 5.59M
Shs Float 5.56M Short Float 0.70% Short Ratio 0.47
Short Interest — 52W High 13.62 52W Low 0.50
Beta — Avg Volume 2.69M Volume 223.68K
Target Price — Recom None Prev Close $0.67
Price $0.76 Change 12.86%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
—
Mean price target
2. Current target
$0.76
Latest analyst target
3. DCF / Fair value
$0.84
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$0.76
Low
—
High
—
Mean
—
News
RSS: Latest SHPH news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2024-12-31 SCHAFER JOSHUA Director — 209,790 — —
2024-12-31 RICHARDS STEVEN M Director — 209,790 — —
2024-12-23 SCHAFER JOSHUA Director — 209,790 — —
2024-12-23 RICHARDS STEVEN M Director — 209,790 — —
2024-12-23 BROWN MILTON Director — 209,790 — —
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
11.92
+54.84%
7.70
+30.61%
5.89
+151.40%
2.34
Research And Development
4.05
+12.05%
3.62
+2.89%
3.52
+235.80%
1.05
Selling General And Administration
7.86
+92.82%
4.08
+71.66%
2.38
+83.22%
1.30
General And Administrative Expense
7.86
+92.82%
4.08
+71.66%
2.38
+83.22%
1.30
Other Gand A
7.86
+92.82%
4.08
+71.66%
2.38
+83.22%
1.30
Total Expenses
11.92
+54.84%
7.70
+30.61%
5.89
+151.40%
2.34
Operating Income
-11.92
-54.84%
-7.70
-30.61%
-5.89
-151.40%
-2.34
Total Operating Income As Reported
-11.92
-54.84%
-7.70
-30.61%
-5.89
-151.40%
-2.34
EBITDA
-11.36
-46.04%
-7.78
-94.94%
-3.99
+11.50%
-4.51
Normalized EBITDA
-11.63
-54.43%
-7.53
-29.68%
-5.81
-129.71%
-2.53
Reconciled Depreciation
0.29
+5210.40%
0.01
-19.79%
0.01
+14.05%
0.01
EBIT
-11.65
-49.66%
-7.78
-94.74%
-4.00
+11.47%
-4.52
Total Unusual Items
0.27
+207.66%
-0.25
-113.72%
1.82
+191.63%
-1.98
Total Unusual Items Excluding Goodwill
0.27
+207.66%
-0.25
-113.72%
1.82
+191.63%
-1.98
Special Income Charges
0.34
+141.11%
-0.83
-74.66%
-0.48
+65.77%
-1.39
Other Special Charges
-0.34
-141.11%
0.83
+74.66%
0.48
-65.77%
1.39
Write Off
—
—
—
—
Net Income
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Pretax Income
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Net Non Operating Interest Income Expense
-0.07
+94.72%
-1.32
+47.46%
-2.52
-275.20%
-0.67
Interest Expense Non Operating
0.07
-94.79%
1.36
-47.59%
2.60
+439.89%
0.48
Net Interest Income
-0.07
+94.72%
-1.32
+47.46%
-2.52
-275.20%
-0.67
Interest Expense
0.07
-94.79%
1.36
-47.59%
2.60
+439.89%
0.48
Interest Income Non Operating
0.00
-97.14%
0.04
-51.80%
0.08
0.00
Interest Income
0.00
-97.14%
0.04
-51.80%
0.08
0.00
Other Income Expense
0.26
+309.22%
-0.13
-106.97%
1.82
+191.63%
-1.98
Other Non Operating Income Expenses
-0.00
-102.73%
0.12
—
0.33
Gain On Sale Of Security
-0.07
-112.73%
0.58
-74.52%
2.29
+490.19%
-0.59
Tax Provision
—
—
—
0.00
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Net Income From Continuing Operation Net Minority Interest
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Net Income From Continuing And Discontinued Operation
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Net Income Continuous Operations
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Normalized Income
-11.99
-34.78%
-8.90
-5.79%
-8.41
-178.94%
-3.01
Net Income Common Stockholders
-11.72
-28.18%
-9.14
-38.71%
-6.59
+2.29%
-6.75
Otherunder Preferred Stock Dividend
—
—
0.00
-100.00%
0.94
Diluted EPS
—
-82.60
+6.40%
-88.25
+29.96%
-126.00
Basic EPS
—
-79.65
+9.75%
-88.25
+29.96%
-126.00
Basic Average Shares
—
0.11
+53.79%
0.07
+39.51%
0.05
Diluted Average Shares
—
0.12
+54.71%
0.07
+39.51%
0.05
Diluted NI Availto Com Stockholders
-11.72
-28.18%
-9.14
-38.71%
-6.59
+2.29%
-6.75
Preferred Stock Dividends
—
—
—
0.81
Total Other Finance Cost
—
—
0.10
-45.11%
0.19
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
10.48
+317.99%
2.51
-57.89%
5.95
-31.22%
8.65
Current Assets
0.50
-77.25%
2.21
-60.47%
5.59
-34.80%
8.58
Cash Cash Equivalents And Short Term Investments
0.33
-82.61%
1.92
-64.86%
5.46
-35.09%
8.42
Cash And Cash Equivalents
0.33
-82.61%
1.92
-25.47%
2.58
-69.39%
8.42
Cash Equivalents
0.08
+6221.70%
0.00
-99.88%
1.03
-65.86%
3.01
Cash Financial
0.26
-86.56%
1.92
+23.79%
1.55
-71.35%
5.41
Other Short Term Investments
—
0.00
-100.00%
2.89
0.00
Receivables
—
0.00
-100.00%
0.01
0.00
Accounts Receivable
—
—
—
—
Accrued Interest Receivable
—
0.00
-100.00%
0.01
0.00
Prepaid Assets
0.17
-41.91%
0.29
+154.01%
0.11
-28.96%
0.16
Other Current Assets
0.00
—
—
—
Total Non Current Assets
9.97
+3276.43%
0.30
-17.66%
0.36
+377.07%
0.08
Net PPE
0.12
-59.47%
0.30
-17.66%
0.36
+422.06%
0.07
Gross PPE
0.12
-59.47%
0.30
-17.66%
0.36
+95.40%
0.18
Accumulated Depreciation
—
—
-0.12
-5.93%
-0.11
Machinery Furniture Equipment
—
—
—
0.01
Other Properties
0.12
-59.47%
0.30
-17.66%
0.36
+95.40%
0.18
Goodwill And Other Intangible Assets
9.84
0.00
—
—
Non Current Deferred Assets
0.01
0.00
—
—
Other Non Current Assets
—
—
—
0.01
Total Liabilities Net Minority Interest
8.22
+357.48%
1.80
-5.21%
1.90
+94.32%
0.98
Current Liabilities
7.97
+419.43%
1.53
+47.16%
1.04
+6.82%
0.98
Payables And Accrued Expenses
5.89
+884.27%
0.60
+51.97%
0.39
+73.17%
0.23
Payables
5.89
+887.21%
0.60
+110.59%
0.28
+119.20%
0.13
Accounts Payable
1.45
+143.68%
0.60
+110.59%
0.28
+119.20%
0.13
Other Payable
4.44
—
—
—
Dividends Payable
—
—
—
0.00
Current Accrued Expenses
0.00
-100.00%
0.00
-98.38%
0.11
+12.55%
0.10
Current Debt And Capital Lease Obligation
0.08
-91.75%
0.94
+44.24%
0.65
-13.34%
0.75
Current Debt
—
0.87
+46.72%
0.60
-13.05%
0.69
Other Current Borrowings
—
0.68
+14.80%
0.60
—
Current Capital Lease Obligation
0.08
+26.74%
0.06
+16.06%
0.05
-16.47%
0.06
Other Current Liabilities
2.00
—
—
—
Total Non Current Liabilities Net Minority Interest
0.25
-3.31%
0.26
-69.15%
0.85
0.00
Long Term Debt And Capital Lease Obligation
0.15
-34.92%
0.24
-45.79%
0.44
0.00
Long Term Debt
—
—
0.14
—
Long Term Capital Lease Obligation
0.15
-34.92%
0.24
-21.71%
0.30
0.00
Stockholders Equity
2.25
+217.91%
0.71
-82.51%
4.06
-47.18%
7.68
Common Stock Equity
2.25
+217.91%
0.71
-82.51%
4.06
-47.18%
7.68
Capital Stock
0.00
+900.00%
0.00
-90.00%
0.00
+17.65%
0.00
Common Stock
0.00
+900.00%
0.00
-90.00%
0.00
+17.65%
0.00
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
1.92
+1079.78%
0.16
+102.95%
0.08
+18.13%
0.07
Ordinary Shares Number
1.92
+1079.78%
0.16
+102.95%
0.08
+18.13%
0.07
Additional Paid In Capital
48.55
+37.60%
35.29
+19.66%
29.49
+11.20%
26.52
Retained Earnings
-46.30
-33.90%
-34.58
-35.96%
-25.43
-34.99%
-18.84
Total Equity Gross Minority Interest
2.25
+217.91%
0.71
-82.51%
4.06
-47.18%
7.68
Total Capitalization
2.25
+217.91%
0.71
-83.08%
4.19
-45.42%
7.68
Working Capital
-7.46
-1202.27%
0.68
-85.12%
4.55
-40.14%
7.60
Invested Capital
2.25
+42.36%
1.58
-66.92%
4.79
-42.76%
8.36
Total Debt
0.23
-80.22%
1.17
+7.89%
1.09
+45.36%
0.75
Net Debt
—
—
—
—
Capital Lease Obligations
0.23
-22.36%
0.30
-16.15%
0.36
+467.64%
0.06
Net Tangible Assets
-7.59
-1169.84%
0.71
-82.51%
4.06
-47.18%
7.68
Tangible Book Value
-7.59
-1169.84%
0.71
-82.51%
4.06
-47.18%
7.68
Current Notes Payable
0.00
-100.00%
0.19
0.00
-100.00%
0.69
Derivative Product Liabilities
0.10
+294.32%
0.03
-93.90%
0.41
0.00
Interest Payable
0.00
-100.00%
0.00
-98.38%
0.11
+12.55%
0.10
Other Equity Interest
—
—
—
—
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-9.48
-29.40%
-7.33
-31.29%
-5.58
-109.31%
-2.67
Cash Flow From Continuing Operating Activities
-9.48
-29.40%
-7.33
-31.29%
-5.58
-109.31%
-2.67
Net Income From Continuing Operations
-11.72
-28.18%
-9.14
-38.71%
-6.59
-31.96%
-5.00
Depreciation Amortization Depletion
0.29
+5210.40%
0.01
-19.79%
0.01
+14.05%
0.01
Depreciation
0.29
+5210.40%
0.01
-19.79%
0.01
+14.05%
0.01
Depreciation And Amortization
0.29
+5210.40%
0.01
-19.79%
0.01
+14.05%
0.01
Other Non Cash Items
0.06
-95.18%
1.29
-46.78%
2.42
+10046.43%
-0.02
Stock Based Compensation
0.93
+259.19%
0.26
+42.75%
0.18
-23.40%
0.24
Asset Impairment Charge
0.11
0.00
—
—
Operating Gains Losses
0.42
+67.38%
0.25
+114.28%
-1.74
-167.78%
2.57
Gain Loss On Investment Securities
0.07
+112.73%
-0.58
+73.70%
-2.22
-385.69%
0.78
Unrealized Gain Loss On Investment Securities
0.00
+102.73%
-0.12
-71.24%
-0.07
0.00
Change In Working Capital
0.54
+289.18%
0.14
-37.04%
0.22
+147.67%
-0.46
Change In Receivables
0.00
-100.00%
0.01
+200.00%
-0.01
0.00
Changes In Account Receivables
—
—
—
0.00
Change In Prepaid Assets
0.12
+169.12%
-0.18
-477.72%
0.05
+129.87%
-0.16
Change In Payables And Accrued Expense
0.42
+40.39%
0.30
+80.33%
0.17
+155.31%
-0.30
Change In Accrued Expense
-0.00
+86.55%
-0.01
-207.74%
0.01
-82.29%
0.07
Change In Payable
0.42
+35.01%
0.31
+103.36%
0.15
+141.60%
-0.37
Change In Account Payable
0.42
+35.01%
0.31
+103.36%
0.15
+141.60%
-0.37
Change In Other Working Capital
-0.00
-959.79%
0.00
-98.21%
0.02
+381.06%
-0.01
Change In Other Current Assets
0.00
0.00
-100.00%
0.01
0.00
Change In Other Current Liabilities
—
—
—
-0.07
Investing Cash Flow
-3.06
-204.83%
2.92
+203.04%
-2.83
0.00
Cash Flow From Continuing Investing Activities
-3.06
-204.83%
2.92
+203.04%
-2.83
0.00
Net PPE Purchase And Sale
—
0.00
+100.00%
-0.02
0.00
Purchase Of PPE
—
0.00
+100.00%
-0.02
0.00
Capital Expenditure
-3.06
—
-0.02
—
Capital Expenditure Reported
-0.01
0.00
—
—
Net Investment Purchase And Sale
0.00
-100.00%
2.92
+203.74%
-2.81
0.00
Purchase Of Investment
0.00
+100.00%
-0.04
+98.55%
-3.00
0.00
Sale Of Investment
0.00
-100.00%
2.96
+1475.00%
0.19
0.00
Net Intangibles Purchase And Sale
-3.04
0.00
—
—
Purchase Of Intangibles
-3.04
0.00
—
—
Financing Cash Flow
10.95
+191.66%
3.76
+46.11%
2.57
-75.71%
10.58
Cash Flow From Continuing Financing Activities
10.95
+191.66%
3.76
+46.11%
2.57
-75.71%
10.58
Net Issuance Payments Of Debt
-0.19
-242.56%
0.13
-95.89%
3.25
+440.94%
0.60
Issuance Of Debt
0.00
-100.00%
1.04
-73.57%
3.94
+504.72%
0.65
Repayment Of Debt
-0.19
+79.01%
-0.91
-32.25%
-0.69
-1270.95%
-0.05
Long Term Debt Issuance
—
0.79
-79.92%
3.94
+555.05%
0.60
Long Term Debt Payments
—
-0.85
0.00
0.00
Net Long Term Debt Issuance
—
-0.06
-101.44%
3.94
+555.05%
0.60
Short Term Debt Issuance
0.00
-100.00%
1.04
0.00
-100.00%
0.05
Short Term Debt Payments
-0.19
+79.01%
-0.91
-32.25%
-0.69
-1270.95%
-0.05
Net Short Term Debt Issuance
-0.19
-242.56%
0.13
+119.47%
-0.69
0.00
Net Common Stock Issuance
9.49
+137.68%
3.99
0.00
-100.00%
10.00
Cash Dividends Paid
0.00
0.00
—
—
Proceeds From Stock Option Exercised
2.28
+313293.14%
0.00
+100.21%
-0.34
—
Net Other Financing Charges
-0.56
-111.09%
-0.26
+21.01%
-0.33
-1826.19%
-0.02
Changes In Cash
-1.59
-141.69%
-0.66
+88.76%
-5.84
-173.82%
7.91
Beginning Cash Position
1.92
-25.47%
2.58
-69.39%
8.42
+1567.60%
0.50
End Cash Position
0.33
-82.61%
1.92
-25.47%
2.58
-69.39%
8.42
Free Cash Flow
-12.54
-71.12%
-7.33
-30.84%
-5.60
-110.03%
-2.67
Interest Paid Supplemental Data
0.13
+44.70%
0.09
-47.46%
0.16
+320.42%
0.04
Income Tax Paid Supplemental Data
0.00
0.00
0.00
0.00
Change In Interest Payable
-0.00
+86.55%
-0.01
-207.74%
0.01
-82.29%
0.07
Common Stock Issuance
9.49
+137.68%
3.99
0.00
-100.00%
10.00
Interest Paid CFF
-0.07
+31.02%
-0.11
—
—
Interest Paid CFO
-0.12
0.00
—
—
Issuance Of Capital Stock
9.49
+137.68%
3.99
0.00
-100.00%
10.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Trades
Date User Broker Pattern Type Position Size Entry Price Trade P&L Status
Posts
Published Title Author Category