Symbols / SKYE $0.70 +0.11% Skye Bioscience, Inc.

Healthcare • Biotechnology • United States • NGM
SKYE Chart
About

Skye Bioscience, Inc., a clinical-stage biotechnology company, focuses on developing molecules that modulate G-protein-coupled receptors (GPCRs) to treat obesity, overweight, and metabolic diseases. Its lead product candidate is nimacimab, a peripherally restricted negative allosteric modulating antibody targeting cannabinoid receptor 1, a key GPCR involved in metabolic regulation. The company was formerly known as Emerald Bioscience, Inc. and changed its name to Skye Bioscience, Inc. in January 2021. Skye Bioscience, Inc. is headquartered in San Diego, California.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 23.33M
Enterprise Value -2.17M Income -55.92M Sales —
Book/sh 0.60 Cash/sh 0.77 Dividend Yield —
Payout 0.00% Employees 12 IPO —
P/E — Forward P/E -0.65 PEG —
P/S — P/B 1.16 P/C —
EV/EBITDA 0.04 EV/Sales — Quick Ratio 3.14
Current Ratio 3.30 Debt/Eq 1.37 LT Debt/Eq —
EPS (ttm) -1.41 EPS next Y -1.07 EPS Growth —
Revenue Growth — Earnings 2026-05-07 ROA -71.93%
ROE -126.85% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 33.38M
Shs Float 21.20M Short Float 6.84% Short Ratio 1.44
Short Interest — 52W High 5.75 52W Low 0.57
Beta 2.87 Avg Volume 583.84K Volume 19.37K
Target Price $8.25 Recom Buy Prev Close $0.70
Price $0.70 Change 0.11%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$8.25
Mean price target
2. Current target
$0.70
Latest analyst target
3. DCF / Fair value
$-12.38
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$0.70
Low
$2.00
High
$20.00
Mean
$8.25

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-09-30 init HC Wainwright & Co. — → Buy $20
2025-08-15 init Evercore ISI Group — → Outperform $10
2025-06-24 reit JMP Securities Market Outperform → Market Outperform $15
2025-03-21 main Craig-Hallum Buy → Buy $14
2025-03-21 reit Citizens Capital Markets Market Outperform → Market Outperform $15
2025-02-28 init William Blair — → Outperform —
2024-09-30 init Scotiabank — → Sector Outperform $20
2024-09-20 reit Piper Sandler Overweight → Overweight $20
2024-09-20 reit Cantor Fitzgerald Overweight → Overweight $14
2024-09-10 init JMP Securities — → Market Outperform $15
2024-09-09 reit Cantor Fitzgerald Overweight → Overweight $14
2024-09-06 reit Cantor Fitzgerald Overweight → Overweight $14
2024-08-27 reit Cantor Fitzgerald Overweight → Overweight $14
2024-07-09 init Craig-Hallum — → Buy $18
2024-07-01 reit Cantor Fitzgerald Overweight → Overweight $14
2024-06-18 reit Cantor Fitzgerald Overweight → Overweight $14
2024-06-17 reit Cantor Fitzgerald Overweight → Overweight $14
2024-05-23 init Cantor Fitzgerald — → Overweight $21
2024-04-12 init Oppenheimer — → Outperform $25
2024-03-14 reit Piper Sandler Overweight → Overweight $20
News
RSS: Latest SKYE news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2025-08-22 SCHWAB ANDREW J. Director and Beneficial Owner of more than 10% of a Class of Security — 231,405 $3.42 $800,548
2025-08-22 5AM PARTNERS VII, LLC Beneficial Owner of more than 10% of a Class of Security — 231,405 $3.42 $800,548
2024-11-18 GRAYSON PAUL A. Director — 86,551 $4.99 $432,061
2024-11-18 DHILLON PUNIT S Chief Executive Officer — 82,910 $4.99 $413,925
2024-11-18 ARSENAULT KAITLYN MELANIE Chief Financial Officer — 43,396 $4.99 $216,652
2024-11-18 ARSENAULT KAITLYN MELANIE Chief Financial Officer — 43,216 $4.99 $215,754
2024-11-18 DIEP TUAN TU Officer — 19,574 $4.99 $97,722
2024-09-13 SCHWAB ANDREW J. Director and Beneficial Owner of more than 10% of a Class of Security — 266,337 $6.06 $1,750,352
2024-09-13 5AM PARTNERS VII, LLC Beneficial Owner of more than 10% of a Class of Security — 266,337 $6.06 $1,750,352
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
58.16
+59.67%
36.43
+166.44%
13.67
+12.93%
12.11
Research And Development
42.36
+126.51%
18.70
+221.36%
5.82
-3.20%
6.01
Selling General And Administration
15.80
-10.85%
17.73
+125.74%
7.85
+28.84%
6.09
General And Administrative Expense
15.80
-10.85%
17.73
+125.74%
7.85
+28.84%
6.09
Other Gand A
15.80
-10.85%
17.73
+125.74%
7.85
+28.84%
6.09
Total Expenses
58.16
+59.67%
36.43
+166.44%
13.67
+12.93%
12.11
Operating Income
-58.16
-59.67%
-36.43
-166.44%
-13.67
-12.93%
-12.11
Total Operating Income As Reported
-58.16
-92.64%
-30.19
+13.08%
-34.74
-89.69%
-18.31
EBITDA
-55.20
-118.25%
-25.29
+30.94%
-36.62
-95.87%
-18.70
Normalized EBITDA
-55.56
-68.95%
-32.88
-121.59%
-14.84
-22.70%
-12.09
Reconciled Depreciation
0.72
+142.22%
0.30
+140.35%
0.12
+8.05%
0.11
EBIT
-55.92
-118.53%
-25.59
+30.36%
-36.74
-95.33%
-18.81
Total Unusual Items
0.36
-95.25%
7.59
+134.86%
-21.78
-229.89%
-6.60
Total Unusual Items Excluding Goodwill
0.36
-95.25%
7.59
+134.86%
-21.78
-229.89%
-6.60
Special Income Charges
0.36
-95.25%
7.59
+134.86%
-21.78
-226.93%
-6.66
Other Special Charges
—
-6.23
-129.60%
21.06
+239.44%
6.21
Restructuring And Mergern Acquisition
—
—
0.41
-10.33%
0.46
Write Off
—
—
—
0.46
Net Income
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Pretax Income
-55.92
-110.56%
-26.56
+29.45%
-37.64
-93.28%
-19.47
Net Non Operating Interest Income Expense
1.88
-17.35%
2.28
+382.71%
-0.81
-5.21%
-0.77
Interest Expense Non Operating
0.00
-100.00%
0.97
+7.85%
0.90
+35.17%
0.66
Net Interest Income
1.88
-17.35%
2.28
+382.71%
-0.81
-5.21%
-0.77
Interest Expense
0.00
-100.00%
0.97
+7.85%
0.90
+35.17%
0.66
Interest Income Non Operating
1.88
-42.27%
3.26
+3164.36%
0.10
+425.87%
0.02
Interest Income
1.88
-42.27%
3.26
+3164.36%
0.10
+425.87%
0.02
Other Income Expense
0.36
-95.25%
7.59
+132.77%
-23.16
-250.84%
-6.60
Other Non Operating Income Expenses
-0.00
+77.18%
-0.00
+99.84%
-1.38
—
Gain On Sale Of Security
—
—
0.00
-99.99%
0.06
Gain On Sale Of Business
—
0.00
+100.00%
-0.41
+10.33%
-0.46
Tax Provision
0.01
-46.38%
0.01
+179.75%
0.00
-46.60%
0.01
Tax Rate For Calcs
0.00
+0.00%
0.00
+0.00%
0.00
+0.00%
0.00
Tax Effect Of Unusual Items
0.08
-95.25%
1.59
+134.86%
-4.57
-229.89%
-1.39
Net Income Including Noncontrolling Interests
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Net Income From Continuing Operation Net Minority Interest
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Net Income From Continuing And Discontinued Operation
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Net Income Continuous Operations
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Normalized Income
-56.21
-72.60%
-32.57
-59.33%
-20.44
-43.27%
-14.27
Net Income Common Stockholders
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Diluted EPS
-1.41
-93.15%
-0.73
+86.41%
-5.37
+38.77%
-8.77
Basic EPS
-1.41
-93.15%
-0.73
+86.41%
-5.37
+38.77%
-8.77
Basic Average Shares
39.66
+8.70%
36.49
+420.79%
7.01
+215.43%
2.22
Diluted Average Shares
39.66
+8.70%
36.49
+420.79%
7.01
+215.43%
2.22
Diluted NI Availto Com Stockholders
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Gain On Sale Of PPE
0.36
-73.44%
1.36
+542.36%
-0.31
0.00
Total Other Finance Cost
—
0.02
+81.57%
0.01
-92.55%
0.12
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
28.31
-61.09%
72.76
+509.39%
11.94
+31.05%
9.11
Current Assets
27.09
-61.75%
70.83
+507.92%
11.65
+30.27%
8.94
Cash Cash Equivalents And Short Term Investments
25.74
-62.38%
68.42
+5345.15%
1.26
+0.96%
1.24
Cash And Cash Equivalents
5.88
-91.40%
68.42
+5345.15%
1.26
+0.96%
1.24
Cash Financial
—
—
1.26
+0.96%
1.24
Other Short Term Investments
19.85
0.00
—
—
Receivables
0.01
+106.79%
0.01
-96.80%
0.16
+113.49%
0.07
Taxes Receivable
0.01
+106.79%
0.01
-96.80%
0.16
+113.49%
0.07
Prepaid Assets
1.33
-39.40%
2.20
+267.95%
0.60
-32.25%
0.88
Restricted Cash
—
0.00
-100.00%
9.08
+198157.69%
0.00
Assets Held For Sale Current
—
—
0.00
-100.00%
6.43
Other Current Assets
0.01
-93.35%
0.21
-62.88%
0.56
+82.39%
0.31
Total Non Current Assets
1.22
-37.03%
1.94
+568.76%
0.29
+73.03%
0.17
Net PPE
1.17
-38.09%
1.88
+569.35%
0.28
+76.84%
0.16
Gross PPE
1.94
-8.36%
2.12
+461.76%
0.38
+136.85%
0.16
Accumulated Depreciation
-0.77
-231.31%
-0.23
-144.69%
-0.10
—
Properties
0.00
0.00
0.00
0.00
Buildings And Improvements
—
—
0.04
-50.74%
0.09
Machinery Furniture Equipment
1.65
+0.38%
1.64
+1216.45%
0.12
—
Other Properties
0.27
-40.73%
0.45
+89.03%
0.24
+234.29%
0.07
Leases
0.02
+0.00%
0.02
+71.41%
0.01
—
Other Non Current Assets
0.05
+0.00%
0.05
+548.81%
0.01
+0.00%
0.01
Total Liabilities Net Minority Interest
8.29
+79.73%
4.61
-67.23%
14.07
+16.12%
12.12
Current Liabilities
8.21
+89.11%
4.34
-68.79%
13.90
+14.70%
12.12
Payables And Accrued Expenses
5.38
+49.19%
3.61
-57.50%
8.49
+219.82%
2.65
Payables
2.03
+257.21%
0.57
-40.50%
0.96
-49.40%
1.89
Accounts Payable
2.03
+257.21%
0.57
-40.50%
0.96
-46.70%
1.79
Other Payable
—
—
—
0.06
Current Accrued Expenses
3.35
+10.22%
3.04
-59.66%
7.53
+886.97%
0.76
Current Debt And Capital Lease Obligation
0.19
+3.96%
0.18
-95.89%
4.44
+124.16%
1.98
Current Debt
—
—
4.37
+129.64%
1.90
Other Current Borrowings
—
—
4.37
+129.64%
1.90
Current Capital Lease Obligation
0.19
+3.96%
0.18
+153.24%
0.07
-8.47%
0.08
Other Current Liabilities
2.63
+379.64%
0.55
-43.36%
0.97
-87.04%
7.48
Total Non Current Liabilities Net Minority Interest
0.08
-69.25%
0.27
+59.53%
0.17
0.00
Long Term Debt And Capital Lease Obligation
0.08
-69.25%
0.27
+59.53%
0.17
0.00
Long Term Capital Lease Obligation
0.08
-69.25%
0.27
+59.53%
0.17
0.00
Stockholders Equity
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Common Stock Equity
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Capital Stock
0.03
+7.76%
0.03
+150.83%
0.01
+237.96%
0.00
Common Stock
0.03
+7.76%
0.03
+150.83%
0.01
+237.96%
0.00
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
33.38
+7.76%
30.97
+150.82%
12.35
+237.95%
3.65
Ordinary Shares Number
33.38
+7.76%
30.97
+150.82%
12.35
+237.95%
3.65
Additional Paid In Capital
206.87
+3.92%
199.07
+94.71%
102.24
+60.43%
63.73
Retained Earnings
-186.87
-42.71%
-130.95
-25.45%
-104.38
-56.41%
-66.74
Total Equity Gross Minority Interest
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Total Capitalization
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Working Capital
18.89
-71.59%
66.49
+3054.83%
-2.25
+29.14%
-3.18
Invested Capital
20.02
-70.62%
68.15
+2942.24%
2.24
+302.87%
-1.10
Total Debt
0.27
-39.94%
0.46
-90.13%
4.62
+132.80%
1.98
Net Debt
—
—
3.12
+372.55%
0.66
Capital Lease Obligations
0.27
-39.94%
0.46
+87.28%
0.24
+209.11%
0.08
Net Tangible Assets
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Tangible Book Value
20.02
-70.62%
68.15
+3296.88%
-2.13
+29.13%
-3.01
Dueto Related Parties Current
—
—
0.00
-100.00%
0.10
Interest Payable
—
0.00
-100.00%
0.36
+2181.38%
0.02
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-43.06
-70.63%
-25.24
-80.89%
-13.95
-9.48%
-12.74
Cash Flow From Continuing Operating Activities
-43.06
-70.63%
-25.24
-80.89%
-13.95
-9.48%
-12.74
Net Income From Continuing Operations
-55.92
-110.50%
-26.57
+29.43%
-37.64
-93.23%
-19.48
Depreciation Amortization Depletion
0.72
+142.22%
0.30
+140.35%
0.12
+8.05%
0.11
Depreciation And Amortization
0.72
+142.22%
0.30
+140.35%
0.12
+8.05%
0.11
Other Non Cash Items
—
-3.64
-330.50%
1.58
-76.86%
6.82
Stock Based Compensation
7.77
-6.61%
8.32
+742.27%
0.99
+56.99%
0.63
Asset Impairment Charge
0.00
-100.00%
0.33
0.00
—
Operating Gains Losses
-0.36
+73.23%
-1.35
-106.28%
21.47
+36050.49%
-0.06
Gain Loss On Investment Securities
—
—
-0.00
+99.99%
-0.06
Net Foreign Currency Exchange Gain Loss
—
0.00
+100.00%
-0.05
0.00
Gain Loss On Sale Of PPE
—
0.00
-100.00%
21.22
0.00
Change In Working Capital
4.73
+280.01%
-2.63
-460.14%
-0.47
+38.40%
-0.76
Change In Prepaid Assets
-0.30
-3832.60%
-0.01
-100.97%
0.80
+26929.69%
-0.00
Change In Payables And Accrued Expense
1.55
+314.94%
-0.72
-556.68%
-0.11
-111.52%
0.95
Change In Accrued Expense
0.16
+215.06%
-0.13
-122.81%
0.59
+283.58%
0.15
Change In Payable
1.40
+337.91%
-0.59
+16.36%
-0.70
-187.69%
0.80
Change In Account Payable
1.40
+337.91%
-0.59
+16.36%
-0.70
-187.69%
0.80
Change In Other Working Capital
—
—
—
—
Change In Other Current Assets
1.36
+192.93%
-1.46
-198.87%
-0.49
-532.91%
0.11
Change In Other Current Liabilities
2.13
+584.68%
-0.44
+34.10%
-0.67
+63.53%
-1.83
Investing Cash Flow
-19.50
-7839.37%
-0.25
-103.72%
6.60
+26.50%
5.21
Cash Flow From Continuing Investing Activities
-19.50
-7839.37%
-0.25
-103.72%
6.60
+26.50%
5.21
Net PPE Purchase And Sale
0.35
+244.31%
-0.25
-104.45%
5.52
+19771.12%
-0.03
Purchase Of PPE
-0.01
+99.61%
-1.60
-12681.09%
-0.01
+55.27%
-0.03
Sale Of PPE
0.36
-73.44%
1.36
-75.45%
5.53
0.00
Capital Expenditure
-0.01
+99.61%
-1.60
-12681.09%
-0.01
+55.27%
-0.03
Net Investment Purchase And Sale
-19.85
0.00
—
—
Purchase Of Investment
-19.85
0.00
—
—
Net Other Investing Changes
—
—
1.08
-79.46%
5.24
Financing Cash Flow
0.03
-99.96%
83.56
+408.18%
16.44
+7975.36%
-0.21
Cash Flow From Continuing Financing Activities
0.03
-99.96%
83.56
+408.18%
16.44
+7975.36%
-0.21
Net Issuance Payments Of Debt
—
0.00
-100.00%
4.71
+2336.82%
-0.21
Issuance Of Debt
—
0.00
-100.00%
4.97
+630.46%
0.68
Repayment Of Debt
—
0.00
+100.00%
-0.26
+70.92%
-0.89
Long Term Debt Issuance
—
—
0.00
-100.00%
0.68
Long Term Debt Payments
—
0.00
+100.00%
-0.26
+70.92%
-0.89
Net Long Term Debt Issuance
—
0.00
+100.00%
-0.26
-23.05%
-0.21
Short Term Debt Issuance
—
0.00
-100.00%
4.97
0.00
Short Term Debt Payments
—
—
-0.01
+99.02%
-0.62
Net Short Term Debt Issuance
—
0.00
-100.00%
4.97
0.00
Net Common Stock Issuance
0.00
-100.00%
83.56
+612.03%
11.73
0.00
Proceeds From Stock Option Exercised
0.03
+426.36%
0.01
0.00
-100.00%
0.00
Net Other Financing Charges
—
—
-0.01
—
Changes In Cash
-62.53
-207.67%
58.08
+539.11%
9.09
+217.43%
-7.74
Beginning Cash Position
68.42
+561.88%
10.34
+727.52%
1.25
-86.10%
8.99
End Cash Position
5.88
-91.40%
68.42
+561.88%
10.34
+727.52%
1.25
Free Cash Flow
-43.07
-60.46%
-26.84
-92.21%
-13.96
-9.34%
-12.77
Interest Paid Supplemental Data
0.00
-100.00%
0.43
+118.47%
0.20
-40.53%
0.33
Income Tax Paid Supplemental Data
0.01
+3.85%
0.01
+44.44%
0.00
-46.60%
0.01
Change In Interest Payable
0.00
+100.00%
-0.36
-200.00%
0.36
+326.77%
-0.16
Common Stock Issuance
0.00
-100.00%
83.56
+612.03%
11.73
0.00
Issuance Of Capital Stock
0.00
-100.00%
83.56
+612.03%
11.73
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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