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About

Sensei Biotherapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of therapeutics for cancer patients. The company's Tumor Microenvironment Activated Biologics platform is designed to generate highly selective therapeutics that disable immunosuppressive signals or activate immunostimulatory signals selectively in the tumor microenvironment. It also offers Solnerstotug, an active monoclonal antibody that is in clinical Phase 1/2 targeting the immune checkpoint VISTA for the treatment of solid tumors. The company's pipeline includes SNS-102 and SNS-103, an active monoclonal antibody, which are in early development stages for the treatment of solid tumors, as well as SNS-201 is a bispecific antibody targeting CD28. It has a collaboration with The University of Washington to conduct preclinical studies for its solnerstotug program. The company was formerly known as Panacea Pharmaceuticals, Inc. Sensei Biotherapeutics, Inc. was incorporated in 1999 and is headquartered in Rockville, Maryland.

Fundamentals
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Sector Healthcare Industry Biotechnology Market Cap 44.23M
Enterprise Value 21.21M Income -24.14M Sales —
Book/sh 18.24 Cash/sh 19.85 Dividend Yield —
Payout 0.00% Employees 14 IPO —
P/E — Forward P/E -31.31 PEG —
P/S — P/B 1.92 P/C —
EV/EBITDA -0.90 EV/Sales — Quick Ratio 5.64
Current Ratio 5.81 Debt/Eq 8.78 LT Debt/Eq —
EPS (ttm) -19.14 EPS next Y -1.12 EPS Growth —
Revenue Growth — Earnings 2025-11-14 07:00 ROA -37.04%
ROE -70.18% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 1.26M
Shs Float 858.19K Short Float 3.08% Short Ratio 0.25
Short Interest — 52W High 35.00 52W Low 5.00
Beta 0.28 Avg Volume 310.36K Volume 247.35K
Target Price — Recom None Prev Close $32.63
Price $35.07 Change 7.48%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
—
Mean price target
2. Current target
$35.07
Latest analyst target
3. DCF / Fair value
$-189.85
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$35.07
Low
—
High
—
Mean
—

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-10-30 down HC Wainwright & Co. Buy → Neutral —
2025-08-05 main HC Wainwright & Co. Buy → Buy $30
2025-03-28 main Oppenheimer Outperform → Outperform $4
2025-03-28 reit HC Wainwright & Co. Buy → Buy $4
2025-01-10 reit HC Wainwright & Co. Buy → Buy $4
2025-01-08 main HC Wainwright & Co. Buy → Buy $4
2024-08-07 reit HC Wainwright & Co. Buy → Buy $4
2024-05-24 reit HC Wainwright & Co. Buy → Buy $4
2024-05-24 reit Stephens & Co. Overweight → Overweight $5
2024-05-14 init Stephens & Co. — → Overweight $5
2023-12-04 init HC Wainwright & Co. — → Buy $4
2022-12-13 init Citigroup — → Buy $6
2022-10-03 up Oppenheimer Perform → Outperform $5
2022-03-10 main Piper Sandler — → Overweight $10
2021-07-01 down Berenberg Buy → Hold $12
2021-06-29 down Oppenheimer Outperform → Perform —
2021-03-01 init Oppenheimer — → Outperform $36
2021-03-01 init Piper Sandler — → Overweight $25
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 6612 54575 — Sale at price 7.92 - 8.59 per share. PEYER JAMES Beneficial Owner of more than 10% of a Class of Security — 2025-12-09 00:00:00 I
1 395 2528 — Conversion of Exercise of derivative security at price 6.40 per share. PEYER JAMES Beneficial Owner of more than 10% of a Class of Security — 2025-12-09 00:00:00 I
2 6612 54575 — Sale at price 7.92 - 8.59 per share. CAMBRIAN BIOPHARMA INC Beneficial Owner of more than 10% of a Class of Security — 2025-12-09 00:00:00 D
3 395 2528 — Conversion of Exercise of derivative security at price 6.40 per share. CAMBRIAN BIOPHARMA INC Beneficial Owner of more than 10% of a Class of Security — 2025-12-09 00:00:00 D
4 21295 228061 — Sale at price 9.06 - 11.40 per share. PEYER JAMES Beneficial Owner of more than 10% of a Class of Security — 2025-12-05 00:00:00 I
5 21295 228061 — Sale at price 9.06 - 11.40 per share. CAMBRIAN BIOPHARMA INC Beneficial Owner of more than 10% of a Class of Security — 2025-12-05 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-27.79M-32.30M-47.02M-36.01M
TotalUnusualItems-951.00K-302.00K0.00567.00K
TotalUnusualItemsExcludingGoodwill-951.00K-302.00K0.00567.00K
NetIncomeFromContinuingOperationNetMinorityInterest-30.16M-34.10M-48.59M-36.79M
ReconciledDepreciation1.32M1.35M1.35M685.00K
EBITDA-28.75M-32.61M-47.02M-35.44M
EBIT-30.07M-33.96M-48.37M-36.12M
NetInterestIncome2.46M3.48M1.56M130.00K
InterestExpense90.00K144.00K219.00K670.00K
InterestIncome2.55M3.62M1.78M800.00K
NormalizedIncome-29.21M-33.80M-48.59M-37.36M
NetIncomeFromContinuingAndDiscontinuedOperation-30.16M-34.10M-48.59M-36.79M
TotalExpenses31.66M37.06M50.19M37.48M
TotalOperatingIncomeAsReported-32.61M-37.06M-50.19M-37.48M
DilutedAverageShares1.26M1.40M1.54M1.39M
BasicAverageShares1.26M1.40M1.54M1.39M
DilutedEPS-24.00-24.40-31.60-26.60
BasicEPS-24.00-24.40-31.60-26.60
DilutedNIAvailtoComStockholders-30.16M-34.10M-48.59M-36.79M
NetIncomeCommonStockholders-30.16M-34.10M-48.59M-36.79M
NetIncome-30.16M-34.10M-48.59M-36.79M
NetIncomeIncludingNoncontrollingInterests-30.16M-34.10M-48.59M-36.79M
NetIncomeContinuousOperations-30.16M-34.10M-48.59M-36.79M
PretaxIncome-30.16M-34.10M-48.59M-36.79M
OtherIncomeExpense-954.00K-517.00K36.00K558.00K
OtherNonOperatingIncomeExpenses-3.00K-215.00K36.00K-9.00K
SpecialIncomeCharges-951.00K-302.00K0.00567.00K
GainOnSaleOfPPE0.00-302.00K0.00-9.00K
OtherSpecialCharges-567.00K
ImpairmentOfCapitalAssets951.00K0.00
NetNonOperatingInterestIncomeExpense2.46M3.48M1.56M130.00K
InterestExpenseNonOperating90.00K144.00K219.00K670.00K
InterestIncomeNonOperating2.55M3.62M1.78M800.00K
OperatingIncome-31.66M-37.06M-50.19M-37.48M
OperatingExpense31.66M37.06M50.19M37.48M
ResearchAndDevelopment18.63M18.30M30.38M21.66M
SellingGeneralAndAdministration13.04M18.77M19.80M15.82M
GeneralAndAdministrativeExpense13.04M18.77M19.80M15.82M
OtherGandA13.04M18.77M19.80M15.82M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2023-12-31
TreasurySharesNumber0.00
OrdinarySharesNumber1.26M1.25M1.54M1.53M
ShareIssued1.26M1.25M1.54M1.53M
TotalDebt3.85M6.21M8.03M2.35M
TangibleBookValue38.39M64.89M103.41M146.51M
InvestedCapital38.39M64.89M103.41M146.51M
WorkingCapital36.48M61.61M99.52M143.65M
NetTangibleAssets38.39M64.89M103.41M146.51M
CapitalLeaseObligations3.85M6.21M8.03M2.35M
CommonStockEquity38.39M64.89M103.41M146.51M
TotalCapitalization38.39M64.89M103.41M146.51M
TotalEquityGrossMinorityInterest38.39M64.89M103.41M146.51M
StockholdersEquity38.39M64.89M103.41M146.51M
GainsLossesNotAffectingRetainedEarnings-13.00K-209.00K-1.00M-333.00K
OtherEquityAdjustments-13.00K-209.00K-1.00M-333.00K
RetainedEarnings-262.05M-231.90M-197.79M-149.21M
AdditionalPaidInCapital300.45M297.00M302.20M296.05M
CapitalStock3.00K3.00K3.00K3.00K
CommonStock3.00K3.00K3.00K3.00K
PreferredStock0.000.000.00
TotalLiabilitiesNetMinorityInterest6.97M9.48M14.97M6.71M
TotalNonCurrentLiabilitiesNetMinorityInterest1.53M3.84M5.90M1.82M
OtherNonCurrentLiabilities67.00K149.00K
PreferredSecuritiesOutsideStockEquity0.00
LongTermDebtAndCapitalLeaseObligation1.53M3.77M5.90M1.67M
LongTermCapitalLeaseObligation1.53M3.77M5.90M1.67M
CurrentLiabilities5.45M5.64M9.07M4.89M
CurrentDebtAndCapitalLeaseObligation2.32M2.44M2.13M680.00K
CurrentCapitalLeaseObligation2.32M2.44M2.13M680.00K
PensionandOtherPostRetirementBenefitPlansCurrent1.88M1.51M2.46M1.75M
PayablesAndAccruedExpenses1.25M1.69M4.47M2.46M
Payables2.46M
AccountsPayable2.46M
TotalAssets45.36M74.37M118.38M153.22M
TotalNonCurrentAssets3.43M7.12M9.79M4.68M
OtherNonCurrentAssets48.00K86.00K63.00K39.00K
NetPPE3.38M7.04M9.72M4.64M
AccumulatedDepreciation-1.50M-1.73M-1.44M-1.19M
GrossPPE4.88M8.77M11.17M5.83M
Leases253.00K253.00K253.00K253.00K
OtherProperties4.27M7.98M10.38M4.97M
MachineryFurnitureEquipment354.00K532.00K532.00K606.00K
Properties0.000.000.000.00
CurrentAssets41.93M67.25M108.59M148.54M
OtherCurrentAssets120.00K325.00K344.00K374.00K
CurrentDeferredAssets0.00
PrepaidAssets474.00K1.17M1.13M547.00K
CashCashEquivalentsAndShortTermInvestments41.34M65.76M107.12M147.62M
OtherShortTermInvestments31.34M52.75M89.32M140.46M
CashAndCashEquivalents9.99M13.01M17.80M7.16M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-24.82M-32.20M-39.35M-32.28M
RepurchaseOfCapitalStock0.00-10.38M0.00
RepaymentOfDebt-811.00K-761.00K-629.00K-255.00K
IssuanceOfDebt0.00
IssuanceOfCapitalStock0.00164.09M
CapitalExpenditure-146.00K-180.00K-321.00K-2.03M
InterestPaidSupplementalData0.0057.00K
EndCashPosition9.99M13.01M17.80M7.16M
BeginningCashPosition13.01M17.80M7.16M16.60M
ChangesInCash-3.02M-4.78M10.64M-9.44M
FinancingCashFlow-787.00K-11.17M-287.00K163.94M
CashFlowFromContinuingFinancingActivities-787.00K-11.17M-287.00K163.94M
NetOtherFinancingCharges-10.00K-76.00K
ProceedsFromStockOptionExercised34.00K48.00K342.00K109.00K
NetPreferredStockIssuance0.0023.49M
PreferredStockIssuance0.0023.49M
NetCommonStockIssuance0.00-10.38M0.00140.59M
CommonStockPayments0.00-10.38M0.00
CommonStockIssuance0.00140.59M
NetIssuancePaymentsOfDebt-811.00K-761.00K-629.00K-255.00K
NetLongTermDebtIssuance-811.00K-761.00K-629.00K-255.00K
LongTermDebtPayments-811.00K-761.00K-629.00K-255.00K
LongTermDebtIssuance0.00
InvestingCashFlow22.44M38.41M49.95M-143.12M
CashFlowFromContinuingInvestingActivities22.44M38.41M49.95M-143.12M
NetInvestmentPurchaseAndSale22.59M38.43M50.26M-141.41M
SaleOfInvestment67.18M59.58M97.12M42.26M
PurchaseOfInvestment-44.59M-21.15M-46.87M-183.67M
NetBusinessPurchaseAndSale0.00
PurchaseOfBusiness0.00
NetPPEPurchaseAndSale-146.00K-14.00K-306.00K-1.71M
SaleOfPPE0.00166.00K15.00K318.00K
PurchaseOfPPE-146.00K-180.00K-321.00K-2.03M
OperatingCashFlow-24.67M-32.02M-39.03M-30.26M
CashFlowFromContinuingOperatingActivities-24.67M-32.02M-39.03M-30.26M
ChangeInWorkingCapital-489.00K-4.33M1.01M117.00K
ChangeInOtherWorkingCapital666.00K-650.00K709.00K837.00K
ChangeInOtherCurrentLiabilities-1.65M-1.27M-1.14M205.00K
ChangeInOtherCurrentAssets244.00K22.00K5.00K-327.00K
ChangeInPayablesAndAccruedExpense-445.00K-2.33M2.02M-1.43M
ChangeInAccruedExpense0.00
ChangeInInterestPayable0.00
ChangeInPayable-1.43M
ChangeInAccountPayable-1.43M
ChangeInPrepaidAssets694.00K-99.00K-582.00K828.00K
OtherNonCashItems1.55M1.36M1.19M57.00K
StockBasedCompensation3.13M4.45M5.81M5.66M
AssetImpairmentCharge951.00K0.00
AmortizationOfSecurities-986.00K-1.06M231.00K615.00K
DepreciationAmortizationDepletion1.32M1.35M1.35M685.00K
DepreciationAndAmortization1.32M1.35M1.35M685.00K
Depreciation1.32M1.35M1.35M685.00K
OperatingGainsLosses302.00K-30.00K-596.00K
GainLossOnInvestmentSecurities-15.00K
GainLossOnSaleOfPPE0.00302.00K-15.00K-29.00K
NetIncomeFromContinuingOperations-30.16M-34.10M-48.59M-36.79M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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