SRPT Chart
About

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, siRNA platform, gene therapy, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 45 skipping; and ELEVIDYS, an AAV-based gene therapy, which is contraindicated in patients with any deletion in exon 8 and/or exon 9 in the Duchenne gene. The company also develops SRP-9003, a gene therapy program for the treatment of LGMD2E; SRP-1001 to selectively target and knockdown DUX4 using RNAi in Phase 1/2a clinical trials; and SRP-1003 for reduction of expression of the DMPK gene in Phase 1/2a clinical trials. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Arrowhead Pharmaceuticals, Inc.; University of Western Australia; Nationwide Children's Hospital; Hansa Biopharma; and Duke University. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 1.79B
Enterprise Value 1.85B Income -713.41M Sales 2.20B
Book/sh 10.87 Cash/sh 8.95 Dividend Yield
Payout 0.00% Employees 835 IPO
P/E Forward P/E 6.16 PEG
P/S 0.82 P/B 1.57 P/C
EV/EBITDA -3.02 EV/Sales 0.84 Quick Ratio 1.33
Current Ratio 2.32 Debt/Eq 91.14 LT Debt/Eq
EPS (ttm) -7.13 EPS next Y 2.77 EPS Growth
Revenue Growth -32.70% Earnings 2026-05-06 ROA -11.24%
ROE -53.47% ROIC Gross Margin -7.43%
Oper. Margin -92.58% Profit Margin -32.45% Shs Outstand 104.99M
Shs Float 91.78M Short Float 23.45% Short Ratio 8.87
Short Interest 52W High 81.87 52W Low 10.42
Beta 0.46 Avg Volume 2.70M Volume 854.62K
Target Price $20.61 Recom Hold Prev Close $16.66
Price $17.09 Change 2.58%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$20.61
Mean price target
2. Current target
$16.84
Latest analyst target
3. DCF / Fair value
$16.44
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$16.84
Low
$5.00
High
$38.00
Mean
$20.61

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-13 main Mizuho Outperform → Outperform $31
2026-03-10 main Citigroup Sell → Sell $9
2026-03-02 reit HC Wainwright & Co. Sell → Sell $5
2026-02-27 main Wells Fargo Overweight → Overweight $38
2026-01-27 reit HC Wainwright & Co. Sell → Sell $5
2026-01-23 main Wedbush Outperform → Outperform $34
2026-01-14 reit HC Wainwright & Co. Sell → Sell $5
2025-12-09 init Wedbush — → Outperform $32
2025-11-05 main Barclays Equal-Weight → Equal-Weight $20
2025-11-05 main Wells Fargo Overweight → Overweight $45
2025-11-05 main Guggenheim Buy → Buy $19
2025-11-05 up Mizuho Neutral → Outperform $26
2025-11-04 main Baird Neutral → Neutral $15
2025-10-30 main Piper Sandler Neutral → Neutral $16
2025-09-22 up BMO Capital Market Perform → Outperform $50
2025-09-15 reit Guggenheim Buy → Buy $22
2025-09-09 main Leerink Partners Market Perform → Market Perform $15
2025-08-25 reit HC Wainwright & Co. Sell → Sell $5
2025-08-21 main B of A Securities Underperform → Underperform $16
2025-08-20 main B of A Securities Underperform → Underperform $17
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 7239 123208.0 Sale at price 17.02 per share. MAYO STEPHEN L. Director 2026-03-12 00:00:00 D
1 8125 nan RODINO-KLAPAC LOUISE Officer 2026-02-27 00:00:00 D
2 8125 nan ESTEPAN IAN MICHAEL Chief Operating Officer 2026-02-27 00:00:00 D
3 7450 102140.0 Conversion of Exercise of derivative security at price 13.71 per share. ESTEPAN IAN MICHAEL Chief Operating Officer 2026-02-26 00:00:00 D
4 10500 143955.0 Conversion of Exercise of derivative security at price 13.71 per share. NICAISE CLAUDE M.D. Director 2026-01-29 00:00:00 D
5 10500 143955.0 Conversion of Exercise of derivative security at price 13.71 per share. BEHRENS M KATHLEEN Director 2026-01-27 00:00:00 D
6 13187 294202.0 Sale at price 22.31 per share. ESTEPAN IAN MICHAEL Chief Operating Officer 2025-12-16 00:00:00 D
7 539084 Stock Award(Grant) at price 0.00 per share. INGRAM DOUGLAS S Chief Executive Officer 2025-12-05 00:00:00 D
8 143875 Stock Award(Grant) at price 0.00 per share. RODINO-KLAPAC LOUISE Officer 2025-09-03 00:00:00 D
9 143875 Stock Award(Grant) at price 0.00 per share. ESTEPAN IAN MICHAEL Chief Operating Officer 2025-09-03 00:00:00 D
Financials
Line Item2025-12-312024-12-312023-12-312022-12-31
TaxEffectOfUnusualItems-8.62M-768.12K-87.96M-25.48M
TaxRateForCalcs0.210.100.210.21
NormalizedEBITDA-578.50M324.73M-34.84M-473.54M
TotalUnusualItems-41.06M-7.84M-418.85M-121.32M
TotalUnusualItemsExcludingGoodwill-41.06M-7.84M-418.85M-121.32M
NetIncomeFromContinuingOperationNetMinorityInterest-713.41M235.24M-535.98M-703.49M
ReconciledDepreciation44.52M37.72M44.40M41.86M
ReconciledCostOfRevenue797.71M283.78M107.50M98.84M
EBITDA-619.56M316.89M-453.69M-594.85M
EBIT-664.09M279.17M-498.09M-636.72M
NetInterestIncome-1.45M53.38M63.96M-25.52M
InterestExpense38.14M18.39M22.01M53.25M
InterestIncome36.69M71.77M85.97M27.72M
NormalizedIncome-680.97M242.31M-205.09M-607.65M
NetIncomeFromContinuingAndDiscontinuedOperation-713.41M235.24M-535.98M-703.49M
TotalExpenses2.86B1.68B1.51B1.47B
TotalOperatingIncomeAsReported-699.78M218.08M-267.82M-536.20M
DilutedAverageShares100.12M107.88M92.40M87.56M
BasicAverageShares100.12M95.08M92.40M87.56M
DilutedEPS-7.132.34-5.80-8.03
BasicEPS-7.132.47-5.80-8.03
DilutedNIAvailtoComStockholders-713.41M235.24M-535.98M-703.49M
NetIncomeCommonStockholders-713.41M235.24M-535.98M-703.49M
NetIncome-713.41M235.24M-535.98M-703.49M
NetIncomeIncludingNoncontrollingInterests-713.41M235.24M-535.98M-703.49M
NetIncomeContinuousOperations-713.41M235.24M-535.98M-703.49M
TaxProvision11.19M25.54M15.88M13.53M
PretaxIncome-702.23M260.77M-520.10M-689.96M
OtherIncomeExpense-43.00M-10.68M-316.23M-128.24M
OtherNonOperatingIncomeExpenses-1.94M-2.85M102.62M-6.92M
SpecialIncomeCharges-25.15M-7.84M-418.85M-121.32M
GainOnSaleOfPPE0.00102.00M
OtherSpecialCharges-16.86M387.33M125.44M10.00M
WriteOff0.000.0030.32M2.58M
ImpairmentOfCapitalAssets4.49M
RestructuringAndMergernAcquisition42.01M7.84M1.20M-6.70M
SecuritiesAmortization-11.23M-157.00K
GainOnSaleOfSecurity-15.91M-2.79M1.53M
NetNonOperatingInterestIncomeExpense-1.45M53.38M63.96M-25.52M
InterestExpenseNonOperating38.14M18.39M22.01M53.25M
InterestIncomeNonOperating36.69M71.77M85.97M27.72M
OperatingIncome-657.77M218.08M-267.82M-536.20M
OperatingExpense2.02B1.36B1.36B1.33B
DepreciationAmortizationDepletionIncomeStatement2.62M2.40M1.56M714.00K
DepreciationAndAmortizationInIncomeStatement2.62M2.40M1.56M714.00K
Amortization2.62M2.40M1.56M714.00K
AmortizationOfIntangiblesIncomeStatement2.62M2.40M1.56M714.00K
ResearchAndDevelopment1.52B804.52M877.39M877.09M
SellingGeneralAndAdministration491.72M557.87M481.87M451.42M
GeneralAndAdministrativeExpense491.72M557.87M481.87M451.42M
OtherGandA262.27M276.07M224.53M157.57M
SalariesAndWages229.45M281.80M257.34M293.85M
GrossProfit1.36B1.58B1.09B793.02M
CostOfRevenue839.61M319.10M150.34M139.99M
TotalRevenue2.20B1.90B1.24B933.01M
OperatingRevenue2.20B1.90B1.24B933.01M
Line Item2025-12-31
TreasurySharesNumber650.88K
OrdinarySharesNumber104.96M96.90M93.73M87.95M
ShareIssued105.62M96.90M93.73M87.95M
NetDebt27.69M34.11M809.57M577.51M
TotalDebt1.04B1.34B1.40B1.62B
TangibleBookValue1.11B1.50B829.72M377.37M
InvestedCapital1.97B2.66B2.10B1.93B
WorkingCapital1.44B2.34B1.93B1.94B
NetTangibleAssets1.11B1.50B829.72M377.37M
CapitalLeaseObligations210.77M205.95M158.81M73.07M
CommonStockEquity1.14B1.53B859.34M384.95M
TotalCapitalization1.97B2.66B1.99B1.93B
TotalEquityGrossMinorityInterest1.14B1.53B859.34M384.95M
StockholdersEquity1.14B1.53B859.34M384.95M
GainsLossesNotAffectingRetainedEarnings272.00K-218.00K918.00K-1.66M
OtherEquityAdjustments272.00K-218.00K918.00K-1.66M
TreasuryStock25.26M0.00
RetainedEarnings-4.88B-4.21B-4.45B-3.91B
AdditionalPaidInCapital6.04B5.74B5.30B4.30B
CapitalStock11.00K10.00K9.00K9.00K
CommonStock11.00K10.00K9.00K9.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest2.21B2.44B2.41B2.74B
TotalNonCurrentLiabilitiesNetMinorityInterest1.11B1.70B1.75B2.12B
OtherNonCurrentLiabilities1.53M49.15M41.10M36.94M
NonCurrentDeferredLiabilities83.91M325.00M437.00M485.00M
NonCurrentDeferredRevenue83.91M325.00M437.00M485.00M
LongTermDebtAndCapitalLeaseObligation1.03B1.33B1.27B1.60B
LongTermCapitalLeaseObligation199.38M192.47M140.97M57.58M
LongTermDebt828.97M1.14B1.13B1.54B
CurrentLiabilities1.10B731.68M653.66M619.60M
OtherCurrentLiabilities15.49M15.05M
CurrentDeferredLiabilities443.40M130.26M50.42M89.24M
CurrentDeferredRevenue443.40M130.26M50.42M89.24M
CurrentDebtAndCapitalLeaseObligation11.39M13.47M123.33M15.49M
CurrentCapitalLeaseObligation11.39M13.47M17.84M15.49M
CurrentDebt105.48M
OtherCurrentBorrowings105.48M
PensionandOtherPostRetirementBenefitPlansCurrent58.61M91.12M78.73M65.95M
CurrentProvisions117.52M109.16M100.08M68.78M
PayablesAndAccruedExpenses464.38M387.68M301.11M380.14M
CurrentAccruedExpenses178.78M155.85M122.42M271.75M
InterestPayable20.71M4.19M4.39M4.96M
Payables285.60M231.83M178.68M108.40M
TotalTaxPayable4.75M17.39M13.77M12.52M
IncomeTaxPayable4.75M17.39M13.77M12.52M
AccountsPayable280.84M214.44M164.92M95.88M
TotalAssets3.35B3.96B3.26B3.13B
TotalNonCurrentAssets811.76M889.71M685.25M570.50M
OtherNonCurrentAssets202.86M206.96M212.32M183.65M
NonCurrentPrepaidAssets95.95M30.34M79.67M102.96M
NonCurrentDeferredAssets2.82M2.25M
NonCurrentDeferredTaxesAssets2.82M2.25M
InvestmentsAndAdvances10.57M136.87M6.53M31.32M
OtherInvestments10.57M136.87M6.53M31.32M
GoodwillAndOtherIntangibleAssets28.95M26.89M29.62M7.58M
OtherIntangibleAssets28.95M26.89M29.62M7.58M
NetPPE470.62M488.65M357.11M244.99M
AccumulatedDepreciation-280.92M-234.15M-190.97M-148.88M
GrossPPE751.53M722.79M548.08M393.87M
Leases349.73M155.07M99.99M97.33M
ConstructionInProgress5.58M165.90M91.09M23.59M
OtherProperties260.81M278.19M238.05M156.76M
MachineryFurnitureEquipment73.03M62.28M60.71M58.08M
BuildingsAndImprovements52.23M51.18M48.06M47.94M
LandAndImprovements10.17M10.17M10.17M10.17M
Properties0.000.000.000.00
CurrentAssets2.54B3.07B2.58B2.56B
OtherCurrentAssets9.20M9.21M12.48M6.82M
PrepaidAssets154.73M309.77M130.77M96.10M
Inventory914.74M749.96M322.86M203.97M
Receivables519.61M649.73M436.98M261.60M
OtherReceivables104.12M34.61M29.79M41.76M
TaxesReceivable15.60M13.13M6.86M1.90M
AccruedInterestReceivable1.66M1.97M2.73M3.31M
AccountsReceivable398.23M601.99M400.33M214.63M
CashCashEquivalentsAndShortTermInvestments939.65M1.35B1.68B1.99B
OtherShortTermInvestments138.37M251.78M1.25B1.02B
CashAndCashEquivalents801.28M1.10B428.43M966.78M
Line Item2025-12-312024-12-312023-12-312022-12-31
FreeCashFlow-315.33M-352.74M-588.34M-357.60M
RepurchaseOfCapitalStock-25.01M0.000.00
RepaymentOfDebt-162.59M-68.00K0.00-823.23M
IssuanceOfDebt0.000.001.13B0.00
IssuanceOfCapitalStock20.00M0.000.000.00
CapitalExpenditure-109.85M-146.96M-87.34M-32.25M
InterestPaidSupplementalData14.91M15.86M15.92M44.42M
IncomeTaxPaidSupplementalData37.63M22.59M15.08M1.70M
EndCashPosition814.41M1.12B444.01M985.80M
BeginningCashPosition1.12B444.01M985.80M2.13B
ChangesInCash-304.18M674.58M-541.79M-1.14B
FinancingCashFlow-168.34M124.81M125.00M232.51M
CashFlowFromContinuingFinancingActivities-168.34M124.81M125.00M232.51M
NetOtherFinancingCharges-19.45M-6.89M-716.00K-7.76M
ProceedsFromStockOptionExercised18.70M124.87M131.89M-70.94M
NetCommonStockIssuance-5.01M0.000.000.00
CommonStockPayments-25.01M0.000.00
CommonStockIssuance20.00M0.000.000.00
NetIssuancePaymentsOfDebt-162.59M-68.00K0.00304.17M
NetLongTermDebtIssuance-162.59M-68.00K0.00304.17M
LongTermDebtPayments-162.59M-68.00K0.00-823.23M
LongTermDebtIssuance0.000.001.13B0.00
InvestingCashFlow69.64M755.56M-165.80M-1.05B
CashFlowFromContinuingInvestingActivities69.64M755.56M-165.80M-1.05B
NetOtherInvestingChanges102.00M-2.43M102.00M
NetInvestmentPurchaseAndSale5.39M902.52M-180.46M-1.01B
SaleOfInvestment295.87M2.00B1.87B923.22M
PurchaseOfInvestment-290.48M-1.10B-2.05B-1.94B
NetBusinessPurchaseAndSale174.09M0.000.000.00
SaleOfBusiness174.09M0.000.00
PurchaseOfBusiness0.00
NetIntangiblesPurchaseAndSale-7.88M-10.00M-11.24M-1.43M
PurchaseOfIntangibles-7.88M-10.00M-11.24M-1.43M
NetPPEPurchaseAndSale-101.97M-136.96M-76.11M-30.82M
PurchaseOfPPE-101.97M-136.96M-76.11M-30.82M
OperatingCashFlow-205.48M-205.79M-500.99M-325.35M
CashFlowFromContinuingOperatingActivities-205.48M-205.79M-500.99M-325.35M
ChangeInWorkingCapital78.04M-716.61M-481.09M-39.47M
ChangeInOtherWorkingCapital72.05M-32.16M-86.83M-89.24M
ChangeInOtherCurrentAssets-79.78M-9.68M1.81M-27.94M
ChangeInPayablesAndAccruedExpense104.27M110.65M-50.13M147.57M
ChangeInPayable104.27M110.65M-50.13M147.57M
ChangeInAccountPayable104.27M110.65M-50.13M147.57M
ChangeInPrepaidAssets78.84M-188.59M-12.52M42.56M
ChangeInInventory-301.09M-395.17M-147.71M-50.78M
ChangeInReceivables203.75M-201.66M-185.70M-61.64M
ChangesInAccountReceivables203.75M-201.66M-185.70M-61.64M
OtherNonCashItems70.59M69.83M-98.01M19.33M
StockBasedCompensation123.40M184.30M182.51M233.02M
AssetImpairmentCharge182.30M0.0030.32M2.58M
AmortizationOfSecurities-5.29M-40.28M-46.18M-10.65M
DepreciationAmortizationDepletion44.52M37.72M44.40M41.86M
DepreciationAndAmortization44.52M37.72M44.40M41.86M
OperatingGainsLosses14.38M24.00M403.02M131.48M
EarningsLossesFromEquityInvestments17.29M0.000.00
GainLossOnInvestmentSecurities7.84M1.20M-6.70M
GainLossOnSaleOfPPE13.95M16.17M14.49M12.73M
NetIncomeFromContinuingOperations-713.41M235.24M-535.98M-703.49M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for SRPT
Date User Broker Pattern Type Position Size Entry Price Trade P&L Status