STRO Chart
About

Sutro Biopharma, Inc. operates as a oncology company. The company develops site-specific and novel-format antibody drug conjugates (ADCs) that enables its proprietary integrated cell-free protein synthesis platform, XpressCF; and site-specific conjugation platform, XpressCF+. Its lead product candidate includes STRO-004, a tissue factor (TF) targeting ADC for the treatment of TF-expressing solid tumors, including cervical, lung, and breast cancer. The company also develops VAX-24 and Vax-31 pneumococcal conjugate vaccine candidates that is in Phase II/III clinical trials for the treatment of invasive pneumococcal disease; and STRO-003, an ADC directed against an anti-receptor tyrosine kinase-like orphan receptor 1 (ROR1) for the treatment of solid tumors, such as triple negative breast cancer, non-small cell lung cancer, and ovarian cancer, as well as hematological cancers. Sutro Biopharma, Inc. has collaboration and license agreements with Vaxcyte to discover and develop vaccine candidates for the treatment or prophylaxis of infectious diseases; Tasly Biopharmaceuticals Co., Ltd. to develop and commercialize STRO-002 in Greater China; Ipsen to develop and commercialize STRO-003, an ADC targeting ROR1; and Astellas Pharma Inc. to develop immunostimulatory ADC. The company was formerly known as Fundamental Applied Biology, Inc. Sutro Biopharma, Inc. was incorporated in 2003 and is headquartered in South San Francisco, California.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 416.74M
Enterprise Value 66.57M Income -216.77M Sales 105.65M
Book/sh -10.26 Cash/sh 19.69 Dividend Yield
Payout 0.00% Employees 178 IPO
P/E Forward P/E -2.35 PEG
P/S 3.94 P/B -2.48 P/C
EV/EBITDA -0.52 EV/Sales 0.63 Quick Ratio 2.39
Current Ratio 2.53 Debt/Eq LT Debt/Eq
EPS (ttm) -26.00 EPS next Y -10.81 EPS Growth
Revenue Growth 13.80% Earnings 2025-11-06 16:00 ROA -25.80%
ROE -18.10% ROIC Gross Margin 136.66%
Oper. Margin -4.01% Profit Margin -205.18% Shs Outstand 16.39M
Shs Float 7.78M Short Float 3.95% Short Ratio 4.70
Short Interest 52W High 26.54 52W Low 5.20
Beta 1.48 Avg Volume 131.32K Volume 179.40K
Target Price $21.25 Recom None Prev Close $24.98
Price $25.43 Change 1.80%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$21.25
Mean price target
2. Current target
$25.43
Latest analyst target
3. DCF / Fair value
$-155.86
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$25.43
Low
$8.00
High
$51.00
Mean
$21.25

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-20 up Citizens Market Perform → Market Outperform $23
2025-12-22 main HC Wainwright & Co. Neutral → Neutral $10
2025-08-12 main Wells Fargo Equal-Weight → Equal-Weight $3
2025-06-16 up Piper Sandler Neutral → Overweight $2
2025-05-19 main B of A Securities Underperform → Underperform $1
2025-04-29 reit HC Wainwright & Co. Neutral → Neutral $2
2025-03-17 down HC Wainwright & Co. Buy → Neutral $2
2025-03-14 down Citizens Capital Markets Market Outperform → Market Perform
2025-03-14 down Wedbush Outperform → Neutral $2
2025-03-14 down B of A Securities Buy → Underperform $1
2024-12-11 main Wells Fargo Equal-Weight → Equal-Weight $4
2024-12-11 reit JMP Securities Market Outperform → Market Outperform $17
2024-11-18 reit HC Wainwright & Co. Buy → Buy $12
2024-10-11 reit Piper Sandler Overweight → Overweight $11
2024-10-11 reit HC Wainwright & Co. Buy → Buy $12
2024-09-16 reit JMP Securities Market Outperform → Market Outperform $17
2024-09-16 reit HC Wainwright & Co. Buy → Buy $12
2024-08-16 main Truist Securities Buy → Buy $15
2024-08-14 reit HC Wainwright & Co. Buy → Buy $12
2024-05-15 main Oppenheimer Outperform → Outperform $10
Insider Transactions
Date Shares Url Text Insider Position Transaction Start Date Ownership Value
0 788 CHUNG JANE Chief Executive Officer 2026-03-04 00:00:00 D nan
1 675 PAULING DAVID J.D. General Counsel 2026-03-04 00:00:00 D nan
2 10938 CHUNG JANE Chief Executive Officer 2026-03-02 00:00:00 D nan
3 3968 GERBER HANS-PETER PH.D. Officer 2026-03-02 00:00:00 D nan
4 3698 PAULING DAVID J.D. General Counsel 2026-03-02 00:00:00 D nan
5 2500 CHUNG JANE Chief Executive Officer 2025-12-12 00:00:00 D nan
6 50000 Purchase at price 0.80 per share. MATSUI CONNIE L Director 2025-10-15 00:00:00 D 39950.0
7 19750 Purchase at price 0.81 per share. CHOW GREGORY KWOK LEE Chief Financial Officer 2025-10-15 00:00:00 D 15998.0
8 12500 Purchase at price 0.80 per share. CHUNG JANE Chief Executive Officer 2025-10-15 00:00:00 D 10011.0
9 17000 Purchase at price 0.80 per share. GERBER HANS-PETER PH.D. Officer 2025-10-15 00:00:00 D 13607.0
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.002.08M2.55M0.00
TaxRateForCalcs0.210.210.210.00
NormalizedEBITDA-186.81M-67.95M-119.80M-93.10M
TotalUnusualItems9.92M12.13M-4.45M
TotalUnusualItemsExcludingGoodwill9.92M12.13M-4.45M
NetIncomeFromContinuingOperationNetMinorityInterest-227.46M-106.79M-119.20M-105.54M
ReconciledDepreciation7.22M6.82M5.69M4.84M
EBITDA-186.81M-58.03M-107.67M-97.56M
EBIT-194.03M-64.85M-113.36M-102.40M
NetInterestIncome13.36M-9.24M109.00K-2.56M
InterestExpense31.07M23.75M3.35M3.14M
InterestIncome44.42M14.51M3.46M577.00K
NormalizedIncome-227.46M-114.63M-128.79M-101.08M
NetIncomeFromContinuingAndDiscontinuedOperation-227.46M-106.79M-119.20M-105.54M
TotalExpenses300.50M243.01M196.72M160.40M
TotalOperatingIncomeAsReported-238.45M-89.28M-128.94M-98.52M
DilutedAverageShares7.68M6.02M5.07M4.61M
BasicAverageShares7.68M6.02M5.07M4.61M
DilutedEPS-29.60-17.80-23.50-22.90
BasicEPS-29.60-17.80-23.50-22.90
DilutedNIAvailtoComStockholders-227.46M-106.79M-119.20M-105.54M
NetIncomeCommonStockholders-227.46M-106.79M-119.20M-105.54M
NetIncome-227.46M-106.79M-119.20M-105.54M
NetIncomeIncludingNoncontrollingInterests-227.46M-106.79M-119.20M-105.54M
NetIncomeContinuousOperations-227.46M-106.79M-119.20M-105.54M
TaxProvision2.36M18.19M2.50M0.00
PretaxIncome-225.10M-88.60M-116.70M-105.54M
OtherIncomeExpense9.92M12.13M-4.45M
GainOnSaleOfSecurity9.92M12.13M-4.45M
NetNonOperatingInterestIncomeExpense13.36M-9.24M109.00K-2.56M
InterestExpenseNonOperating31.07M23.75M3.35M3.14M
InterestIncomeNonOperating44.42M14.51M3.46M577.00K
OperatingIncome-238.45M-89.28M-128.94M-98.52M
OperatingExpense300.50M243.01M196.72M160.40M
ResearchAndDevelopment252.04M180.43M137.17M104.40M
SellingGeneralAndAdministration48.45M62.58M59.54M56.00M
GeneralAndAdministrativeExpense48.45M62.58M59.54M56.00M
OtherGandA48.45M62.58M59.54M56.00M
TotalRevenue62.04M153.73M67.77M61.88M
OperatingRevenue62.04M153.73M67.77M61.88M
Line Item2023-12-31
TreasurySharesNumber0.00
OrdinarySharesNumber8.25M6.10M5.75M4.63M
ShareIssued8.25M6.10M5.75M4.63M
TotalDebt23.15M33.63M50.43M57.37M
TangibleBookValue44.60M149.65M217.05M252.56M
InvestedCapital44.60M153.71M233.32M277.68M
WorkingCapital211.42M327.80M286.61M176.78M
NetTangibleAssets44.60M149.65M217.05M252.56M
CapitalLeaseObligations23.15M29.57M34.16M32.26M
CommonStockEquity44.60M149.65M217.05M252.56M
TotalCapitalization44.60M149.65M220.82M268.30M
TotalEquityGrossMinorityInterest44.60M149.65M217.05M252.56M
StockholdersEquity44.60M149.65M217.05M252.56M
GainsLossesNotAffectingRetainedEarnings39.00K21.00K-618.00K-314.00K
OtherEquityAdjustments39.00K21.00K-618.00K-314.00K
RetainedEarnings-786.87M-559.41M-452.62M-333.41M
AdditionalPaidInCapital831.35M708.98M670.22M586.24M
CapitalStock83.00K61.00K58.00K46.00K
CommonStock83.00K61.00K58.00K46.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest342.61M321.09M189.90M88.84M
TotalNonCurrentLiabilitiesNetMinorityInterest210.71M227.34M123.35M47.11M
OtherNonCurrentLiabilities1.69M1.69M119.00K146.00K
NonCurrentDeferredLiabilities193.34M202.49M89.89M0.00
NonCurrentDeferredRevenue193.34M202.49M89.89M0.00
LongTermDebtAndCapitalLeaseObligation15.67M23.15M33.34M46.96M
LongTermCapitalLeaseObligation15.67M23.15M29.57M31.22M
LongTermDebt3.77M15.74M
CurrentLiabilities131.89M93.75M66.55M41.74M
OtherCurrentLiabilities4.01M3.90M3.08M3.08M
CurrentDeferredLiabilities69.78M20.67M16.76M5.50M
CurrentDeferredRevenue69.78M20.67M16.76M5.50M
CurrentDebtAndCapitalLeaseObligation7.48M10.48M17.09M10.41M
CurrentCapitalLeaseObligation7.48M6.42M4.58M1.04M
CurrentDebt4.06M12.50M9.38M
OtherCurrentBorrowings4.06M12.50M9.38M
PensionandOtherPostRetirementBenefitPlansCurrent12.90M14.69M13.14M11.42M
PayablesAndAccruedExpenses37.72M44.02M16.48M14.41M
CurrentAccruedExpenses27.22M19.41M11.68M8.40M
Payables10.49M24.61M4.80M6.01M
TotalTaxPayable18.00K15.16M0.00
AccountsPayable10.47M9.44M4.80M6.01M
TotalAssets387.21M470.74M406.94M341.41M
TotalNonCurrentAssets43.90M49.19M53.79M122.89M
OtherNonCurrentAssets8.03M4.44M2.73M2.53M
InvestmentsAndAdvances0.0068.78M
InvestmentinFinancialAssets0.0068.78M
AvailableForSaleSecurities68.78M
NetPPE35.87M44.76M51.06M51.59M
AccumulatedDepreciation-48.63M-42.16M-37.91M-33.43M
GrossPPE84.50M86.92M88.97M85.02M
Leases24.20M23.61M23.21M23.65M
ConstructionInProgress497.00K497.00K1.69M506.00K
OtherProperties57.93M60.82M62.29M59.27M
MachineryFurnitureEquipment1.87M1.99M1.78M1.59M
Properties0.000.000.000.00
CurrentAssets343.31M421.54M353.15M218.51M
OtherCurrentAssets17.80M9.85M11.67M8.12M
PrepaidAssets8.12M
Receivables8.62M36.08M7.12M12.45M
AccountsReceivable8.62M36.08M7.12M12.45M
CashCashEquivalentsAndShortTermInvestments316.89M375.62M334.36M197.94M
OtherShortTermInvestments126.59M306.35M287.11M167.52M
CashAndCashEquivalents190.30M69.27M47.25M30.41M
CashEquivalents29.45M
CashFinancial963.00K
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-194.64M-115.93M-4.31M-97.00M
RepurchaseOfCapitalStock0.000.00-7.00K
RepaymentOfDebt-4.08M-12.50M-9.38M0.00
IssuanceOfDebt0.000.00
IssuanceOfCapitalStock96.53M11.97M56.27M0.00
CapitalExpenditure-3.10M-4.32M-7.86M-15.32M
InterestPaidSupplementalData310.00K1.13M1.87M2.05M
IncomeTaxPaidSupplementalData17.52M379.00K0.00103.00K
EndCashPosition191.16M70.14M48.13M31.29M
BeginningCashPosition70.14M48.13M31.29M207.02M
ChangesInCash121.02M22.01M16.84M-175.74M
FinancingCashFlow94.05M137.55M48.31M3.26M
CashFlowFromContinuingFinancingActivities94.05M137.55M48.31M3.26M
NetOtherFinancingCharges-509.00K135.72M-463.00K-987.00K
ProceedsFromStockOptionExercised2.12M2.37M1.88M4.25M
NetCommonStockIssuance96.53M11.97M56.27M-7.00K
CommonStockPayments0.000.00-7.00K
CommonStockIssuance96.53M11.97M56.27M0.00
NetIssuancePaymentsOfDebt-4.08M-12.50M-9.38M0.00
NetLongTermDebtIssuance-4.08M-12.50M-9.38M0.00
LongTermDebtPayments-4.08M-12.50M-9.38M0.00
LongTermDebtIssuance0.000.00
InvestingCashFlow218.51M-3.92M-35.02M-97.31M
CashFlowFromContinuingInvestingActivities218.51M-3.92M-35.02M-97.31M
NetOtherInvestingChanges9.00K9.00K
NetInvestmentPurchaseAndSale221.61M391.00K-27.17M-82.00M
SaleOfInvestment683.13M460.69M189.50M166.73M
PurchaseOfInvestment-461.52M-460.30M-216.67M-248.73M
NetPPEPurchaseAndSale-3.10M-4.32M-7.86M-15.32M
PurchaseOfPPE-3.10M-4.32M-7.86M-15.32M
OperatingCashFlow-191.54M-111.62M3.55M-81.68M
CashFlowFromContinuingOperatingActivities-191.54M-111.62M3.55M-81.68M
ChangeInWorkingCapital8.90M-34.38M104.41M-17.62M
ChangeInOtherWorkingCapital6.06M-31.05M95.37M-12.61M
ChangeInOtherCurrentLiabilities-6.42M-4.58M1.90M-2.73M
ChangeInPayablesAndAccruedExpense-6.65M30.11M5.34M8.57M
ChangeInAccruedExpense-7.35M25.30M6.56M5.87M
ChangeInPayable706.00K4.81M-1.23M2.71M
ChangeInAccountPayable706.00K4.81M-1.23M2.71M
ChangeInPrepaidAssets-11.56M109.00K-3.54M-3.96M
ChangeInReceivables27.46M-28.96M5.34M-6.89M
ChangesInAccountReceivables27.46M-28.96M5.34M-6.89M
OtherNonCashItems36.97M16.82M2.92M6.16M
StockBasedCompensation24.69M24.91M26.30M23.24M
UnrealizedGainLossOnInvestmentSecurities0.00-9.92M-12.13M4.45M
AmortizationOfSecurities-9.72M-9.07M-364.00K2.78M
DepreciationAmortizationDepletion7.22M6.82M5.69M4.84M
DepreciationAndAmortization7.22M6.82M5.69M4.84M
OperatingGainsLosses-32.14M-4.07M
GainLossOnInvestmentSecurities-32.14M-4.07M
NetIncomeFromContinuingOperations-227.46M-106.79M-119.20M-105.54M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for STRO
Date User Broker Pattern Type Position Size Entry Price Trade P&L Status