Symbols / VOR $17.84 +21.36% Vor Biopharma Inc.

Healthcare • Biotechnology • United States • NMS
VOR Chart
About

Vor Biopharma Inc. operates as a clinical-stage cell and genome engineering company. The company offers the Vor Bio platform, a technology platform for the treatment of acute myeloid leukemia (AML) and other blood cancers. It develops tremtelectogene empogeditemcel (trem-cel), a genome-edited hematopoietic stem and progenitor allogeneic donor product candidate to treat acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and other blood cancers; trem-cel in combination with Mylotarg to treat patients in VBP101, which is in phase 1 / 2; and VCAR33, a CAR-T therapy designed to target CD33, which is under preclinical studies to treat AML post-transplant. The company also develops trem-cel + VCAR33 treatment system, CD33-directed CAR-T program, which is under pre-clinical studies for the treatment of AML; VADC45 for the treatment of hematologic malignancies, conditioning, and immune reset, which is under preclinical studies; and CD33-CLL1 treatment system made with CD33-CLL1 multiplex-edited HSC therapy and a CD33-CLL1 multi-specific CAR-T therapy, which is under preclinical studies for the treatment of AML. It has a license agreement with Columbia University and the National Institutes of Health for patents; and with Editas Medicine, Inc. for ex-vivo Cas9 gene-edited HSC therapies for the treatment and/or prevention of hematological malignancies. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 871.44M
Enterprise Value -14.37M Income -2.45B Sales —
Book/sh -246.54 Cash/sh 16.37 Dividend Yield —
Payout 0.00% Employees 154 IPO —
P/E — Forward P/E -3.19 PEG —
P/S — P/B -0.07 P/C —
EV/EBITDA 0.04 EV/Sales — Quick Ratio 9.05
Current Ratio 9.16 Debt/Eq — LT Debt/Eq —
EPS (ttm) -70.50 EPS next Y -5.59 EPS Growth —
Revenue Growth — Earnings 2026-05-15 ROA -144.27%
ROE — ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 48.85M
Shs Float 7.21M Short Float 9.09% Short Ratio 5.44
Short Interest — 52W High 65.80 52W Low 2.62
Beta 2.04 Avg Volume 935.36K Volume 2.41M
Target Price $43.29 Recom Strong_buy Prev Close $14.70
Price $17.84 Change 21.36%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$43.29
Mean price target
2. Current target
$17.84
Latest analyst target
3. DCF / Fair value
$-67.58
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$17.84
Low
$30.00
High
$55.00
Mean
$43.29

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-31 main Wedbush Neutral → Neutral $15
2026-03-30 init Jefferies — → Buy $50
2026-03-19 init Wells Fargo — → Overweight $30
2026-01-09 init Citigroup — → Buy $50
2025-12-19 main JP Morgan Overweight → Overweight $40
2025-12-17 init TD Cowen — → Buy —
2025-12-09 init JP Morgan — → Overweight $43
2025-11-14 main HC Wainwright & Co. Buy → Buy $32
2025-10-29 main HC Wainwright & Co. Buy → Buy $55
2025-10-15 up Baird Neutral → Outperform $64
2025-08-14 reit HC Wainwright & Co. Buy → Buy $3
2025-06-30 up HC Wainwright & Co. Neutral → Buy $3
2025-06-27 main Baird Neutral → Neutral $1
2025-06-26 reit Wedbush Neutral → Neutral $0
2025-05-09 down JMP Securities Market Outperform → Market Perform $6
2025-05-09 down HC Wainwright & Co. Buy → Neutral —
2025-03-21 reit Oppenheimer Outperform → Outperform $8
2025-03-21 main Stifel Buy → Buy $5
2025-03-21 main HC Wainwright & Co. Buy → Buy $13
2024-12-10 reit HC Wainwright & Co. Buy → Buy $18
News
RSS: Latest VOR news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2025-10-30 RA CAPITAL MANAGEMENT, L.P. Beneficial Owner of more than 10% of a Class of Security — 400,408 $25.12 $10,368,938
2025-10-27 RA CAPITAL MANAGEMENT, L.P. Beneficial Owner of more than 10% of a Class of Security — 221,166 $28.01 $6,204,863
2025-10-21 RA CAPITAL MANAGEMENT, L.P. Beneficial Owner of more than 10% of a Class of Security — 117,050 $28.11 $3,433,992
2025-10-21 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 37,533 $30.05 $1,133,103
2025-10-17 RA CAPITAL HEALTHCARE FUND,L.P. Director and Beneficial Owner of more than 10% of a Class of Security — 464,025 $29.12 $13,707,361
2025-10-16 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 73,676 $30.45 $2,348,744
2025-10-14 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 96,657 $30.32 $3,003,706
2025-10-09 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 124,146 $31.92 $4,116,369
2025-10-07 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 98,387 $33.84 $3,553,499
2025-10-03 REPROGRAMMED INTERCHANGE LLC Beneficial Owner of more than 10% of a Class of Security — 41,752 $37.21 $1,646,237
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Total Revenue
0.00
0.00
0.00
0.00
Operating Revenue
0.00
0.00
0.00
0.00
Operating Expense
121.19
-3.85%
126.04
+34.92%
93.42
+35.35%
69.02
Research And Development
93.31
-1.07%
94.31
+46.11%
64.55
+35.81%
47.53
Selling General And Administration
27.88
-12.12%
31.72
+9.88%
28.87
+34.34%
21.49
General And Administrative Expense
27.88
-12.12%
31.72
+9.88%
28.87
+34.34%
21.49
Other Gand A
27.88
-12.12%
31.72
+9.88%
28.87
+34.34%
21.49
Total Expenses
121.19
-3.85%
126.04
+34.92%
93.42
+35.35%
69.02
Operating Income
-121.19
+3.85%
-126.04
-34.92%
-93.42
-35.35%
-69.02
Total Operating Income As Reported
-121.19
+3.85%
-126.04
-34.92%
-93.42
-35.35%
-69.02
EBITDA
-117.66
+3.99%
-122.54
-34.82%
-90.89
-34.49%
-67.58
Normalized EBITDA
-117.66
+3.99%
-122.54
-34.82%
-90.89
-34.49%
-67.58
Reconciled Depreciation
3.53
+1.03%
3.49
+38.30%
2.52
+76.08%
1.43
EBIT
-121.19
+3.85%
-126.04
-34.92%
-93.42
-35.35%
-69.02
Net Income
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Pretax Income
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Net Non Operating Interest Income Expense
4.27
-47.74%
8.17
+517.30%
1.32
+1012.61%
0.12
Net Interest Income
4.27
-47.74%
8.17
+517.30%
1.32
+1012.61%
0.12
Interest Income Non Operating
4.27
-47.74%
8.17
+517.30%
1.32
+1012.61%
0.12
Interest Income
4.27
-47.74%
8.17
+517.30%
1.32
+1012.61%
0.12
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Net Income From Continuing Operation Net Minority Interest
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Net Income From Continuing And Discontinued Operation
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Net Income Continuous Operations
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Normalized Income
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Net Income Common Stockholders
-116.91
+0.81%
-117.86
-27.98%
-92.09
-31.32%
-70.13
Diluted EPS
-34.00
+2.86%
-35.00
+24.89%
-46.60
-10.95%
-42.00
Basic EPS
-34.00
+2.86%
-35.00
+24.89%
-46.60
-10.95%
-42.00
Basic Average Shares
3.44
+2.25%
3.36
+69.89%
1.98
+18.30%
1.67
Diluted Average Shares
3.44
+2.25%
3.36
+69.89%
1.98
+18.30%
1.67
Diluted NI Availto Com Stockholders
-116.91
+0.81%
-117.86
-27.98%
-92.09
-31.32%
-70.13
Preferred Stock Dividends
—
—
—
1.23
Line Item Trend 2024-12-31 2021-12-31
Total Assets
142.89
-41.10%
242.59
Current Assets
96.51
-54.99%
214.40
Cash Cash Equivalents And Short Term Investments
91.93
-55.69%
207.47
Cash And Cash Equivalents
81.95
-31.60%
119.80
Other Short Term Investments
9.98
-88.62%
87.67
Prepaid Assets
4.20
-13.13%
4.84
Other Current Assets
0.38
-81.85%
2.09
Total Non Current Assets
46.38
+64.53%
28.19
Net PPE
41.59
+84.65%
22.52
Gross PPE
52.80
+114.58%
24.61
Accumulated Depreciation
-11.21
-438.10%
-2.08
Properties
—
0.00
Machinery Furniture Equipment
1.05
+231.86%
0.32
Construction In Progress
0.04
0.00
Other Properties
51.71
+112.90%
24.29
Leases
—
0.06
Other Non Current Assets
4.80
-15.38%
5.67
Total Liabilities Net Minority Interest
46.23
+75.59%
26.33
Current Liabilities
18.61
+83.32%
10.15
Payables And Accrued Expenses
8.19
+165.45%
3.08
Payables
1.50
-2.59%
1.54
Accounts Payable
1.50
-2.59%
1.54
Current Accrued Expenses
6.68
+334.03%
1.54
Pensionand Other Post Retirement Benefit Plans Current
5.85
+40.07%
4.18
Current Debt And Capital Lease Obligation
4.21
+129.20%
1.84
Current Capital Lease Obligation
4.21
+129.20%
1.84
Other Current Liabilities
0.36
-66.13%
1.05
Total Non Current Liabilities Net Minority Interest
27.61
+70.74%
16.17
Long Term Debt And Capital Lease Obligation
27.61
+70.74%
16.17
Long Term Capital Lease Obligation
27.61
+70.74%
16.17
Stockholders Equity
96.66
-55.30%
216.26
Common Stock Equity
96.66
-55.30%
216.26
Capital Stock
0.01
+225.00%
0.00
Common Stock
0.01
+225.00%
0.00
Preferred Stock
0.00
0.00
Share Issued
6.24
+233.85%
1.87
Ordinary Shares Number
6.24
+235.65%
1.86
Treasury Shares Number
0.00
-100.00%
0.01
Additional Paid In Capital
553.62
+59.83%
346.38
Retained Earnings
-456.99
-251.20%
-130.12
Gains Losses Not Affecting Retained Earnings
0.02
0.00
Other Equity Adjustments
0.02
—
Total Equity Gross Minority Interest
96.66
-55.30%
216.26
Total Capitalization
96.66
-55.30%
216.26
Working Capital
77.89
-61.86%
204.25
Invested Capital
96.66
-55.30%
216.26
Total Debt
31.83
+76.71%
18.01
Capital Lease Obligations
31.83
+76.71%
18.01
Net Tangible Assets
96.66
-55.30%
216.26
Tangible Book Value
96.66
-55.30%
216.26
Line Item Trend 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Operating Cash Flow
-99.66
+0.63%
-100.29
-17.79%
-85.14
-23.14%
-69.14
Cash Flow From Continuing Operating Activities
-99.66
+0.63%
-100.29
-17.79%
-85.14
-23.14%
-69.14
Net Income From Continuing Operations
-116.91
+0.81%
-117.86
-27.98%
-92.09
-33.67%
-68.90
Depreciation Amortization Depletion
3.53
+1.03%
3.49
+38.30%
2.52
+76.08%
1.43
Depreciation
3.53
+1.03%
3.49
+38.30%
2.52
+76.08%
1.43
Depreciation And Amortization
3.53
+1.03%
3.49
+38.30%
2.52
+76.08%
1.43
Other Non Cash Items
5.04
+6.64%
4.73
+32.11%
3.58
+12.13%
3.19
Stock Based Compensation
9.85
-26.31%
13.36
+24.94%
10.70
+147.86%
4.32
Operating Gains Losses
-0.02
—
—
—
Gain Loss On Sale Of PPE
-0.02
0.00
—
—
Change In Working Capital
0.01
-99.23%
0.65
+106.61%
-9.84
-7.09%
-9.19
Change In Prepaid Assets
-0.83
-125.54%
3.27
+1353.33%
0.23
+103.54%
-6.36
Change In Payables And Accrued Expense
2.24
-21.37%
2.85
+155.83%
1.11
+175.06%
0.41
Change In Other Current Assets
2.43
+228.72%
-1.89
-161.72%
-0.72
-7.93%
-0.67
Change In Other Current Liabilities
-3.83
-6.89%
-3.58
+65.73%
-10.45
-308.52%
-2.56
Investing Cash Flow
96.86
+36.40%
71.01
+175.47%
-94.09
-2.66%
-91.65
Cash Flow From Continuing Investing Activities
96.86
+36.40%
71.01
+175.47%
-94.09
-2.66%
-91.65
Net PPE Purchase And Sale
-0.23
+78.58%
-1.07
+87.37%
-8.46
-117.31%
-3.89
Purchase Of PPE
-0.23
+78.58%
-1.07
+87.37%
-8.46
-117.31%
-3.89
Capital Expenditure
-0.23
+78.58%
-1.07
+87.37%
-8.46
-117.31%
-3.89
Net Investment Purchase And Sale
97.09
+34.70%
72.08
+184.17%
-85.63
+2.42%
-87.76
Purchase Of Investment
-9.91
+86.77%
-74.92
+39.18%
-123.19
-40.38%
-87.76
Sale Of Investment
107.00
-27.21%
147.00
+291.37%
37.56
0.00
Financing Cash Flow
53.39
+1717.29%
2.94
-97.49%
117.14
-49.71%
232.91
Cash Flow From Continuing Financing Activities
53.39
+1717.29%
2.94
-97.49%
117.14
-49.71%
232.91
Net Common Stock Issuance
55.83
+1119.42%
4.58
-96.05%
115.97
-38.70%
189.20
Proceeds From Stock Option Exercised
-0.11
+88.30%
-0.92
-179.23%
1.17
+110.67%
0.55
Net Other Financing Charges
-2.33
-224.27%
-0.72
—
-2.21
Changes In Cash
50.59
+292.02%
-26.35
+57.57%
-62.09
-186.10%
72.12
Beginning Cash Position
33.77
-43.82%
60.12
-50.81%
122.21
+143.95%
50.10
End Cash Position
84.36
+149.79%
33.77
-43.82%
60.12
-50.81%
122.21
Free Cash Flow
-99.89
+1.45%
-101.36
-8.28%
-93.61
-28.16%
-73.04
Amortization Of Securities
-1.15
+75.34%
-4.66
-38733.33%
-0.01
—
Common Stock Issuance
55.83
+1119.42%
4.58
-96.05%
115.97
-38.70%
189.20
Issuance Of Capital Stock
55.83
+1119.42%
4.58
-96.05%
115.97
-50.56%
234.57
Net Preferred Stock Issuance
—
—
0.00
-100.00%
45.38
Preferred Stock Issuance
—
—
0.00
-100.00%
45.38
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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