Symbols / ZNTL $4.33 +56.70% Zentalis Pharmaceuticals, Inc.

Healthcare • Biotechnology • United States • NGM
ZNTL Chart
About

Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers in the United States. The company develops azenosertib, which is in a Phase 3 clinical trial for the treatment of ovarian cancer and other tumor types. It also develops ZN-c3-001, a phase 1 study that evaluated azenosertib monotherapy in solid tumors; and MAMMOTH (ZN-c3-006) is a Phase 1/2 clinical trial of azenosertib in patients with PARP-inhibitor resistant ovarian cancer. It has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC. Zentalis Pharmaceuticals, Inc. was incorporated in 2014 and is headquartered in San Diego, California.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 306.78M
Enterprise Value -10.55M Income -137.06M Sales —
Book/sh 3.13 Cash/sh 3.47 Dividend Yield —
Payout 0.00% Employees 106 IPO —
P/E — Forward P/E -2.55 PEG —
P/S — P/B 1.38 P/C —
EV/EBITDA 0.07 EV/Sales — Quick Ratio 6.73
Current Ratio 6.93 Debt/Eq 18.30 LT Debt/Eq —
EPS (ttm) -1.91 EPS next Y -1.70 EPS Growth —
Revenue Growth — Earnings 2026-05-14 ROA -24.48%
ROE -49.54% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 70.93M
Shs Float 48.67M Short Float 7.62% Short Ratio 5.74
Short Interest — 52W High 4.36 52W Low 1.01
Beta 1.66 Avg Volume 1.09M Volume 10.44M
Target Price $5.31 Recom Buy Prev Close $2.76
Price $4.33 Change 56.70%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$5.31
Mean price target
2. Current target
$4.33
Latest analyst target
3. DCF / Fair value
$-19.25
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$4.33
Low
$2.00
High
$10.00
Mean
$5.31

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-27 reit Guggenheim Buy → Buy $6
2025-11-12 main Morgan Stanley Equal-Weight → Equal-Weight $4
2025-08-07 main Wells Fargo Equal-Weight → Equal-Weight $5
2025-05-15 reit Wedbush Neutral → Neutral $4
2025-05-15 reit HC Wainwright & Co. Buy → Buy $10
2025-03-28 reit Wedbush Neutral → Neutral $4
2025-03-27 reit HC Wainwright & Co. Buy → Buy $10
2025-03-17 reit HC Wainwright & Co. Buy → Buy $10
2025-01-30 main Wells Fargo Equal-Weight → Equal-Weight $6
2025-01-29 main HC Wainwright & Co. Buy → Buy $10
2025-01-28 main UBS Neutral → Neutral $2
2024-11-15 main Guggenheim Buy → Buy $8
2024-11-15 reit HC Wainwright & Co. Buy → Buy $20
2024-09-16 reit Oppenheimer Outperform → Outperform $20
2024-08-12 up Wedbush Underperform → Neutral $4
2024-08-12 reit HC Wainwright & Co. Buy → Buy $20
2024-06-20 down UBS Buy → Neutral $5
2024-06-18 down Wells Fargo Overweight → Equal-Weight $9
2024-06-18 main Stifel Buy → Buy $10
2024-06-18 main HC Wainwright & Co. Buy → Buy $20
News
RSS: Latest ZNTL news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-02-10 VULTAGGIO VINCENT Officer — 40,224 $2.39 $97,557
2026-02-09 EASTLAND JULIA MARIE Chief Executive Officer — 8,755 $2.39 $21,239
2026-02-09 BRUNS INGMAR Officer — 3,297 $2.39 $7,998
2026-02-03 VULTAGGIO VINCENT Officer — 3,096 $2.52 $7,875
2025-12-15 MATRIX CAPITAL MANAGEMENT COMPANY, LP Beneficial Owner of more than 10% of a Class of Security — 7,500,000 $1.33 $9,975,000
2025-06-17 MYERS SCOTT DUNSETH Director — 57,603 $0.00 $0
2025-06-17 WALKER LUKE NATHANIEL Director — 57,603 $0.00 $0
2025-06-17 JOHNSON DAVID MICHAEL Director — 57,603 $0.00 $0
2025-06-17 SKVARKA JAN Director — 57,603 $0.00 $0
2025-06-17 KARIUKI ENOCH Director — 57,603 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
-100.00%
67.42
0.00
0.00
Operating Revenue
0.00
-100.00%
67.42
0.00
0.00
Operating Expense
145.01
-43.11%
254.88
+0.37%
253.94
+11.73%
227.29
Research And Development
107.30
-36.05%
167.77
-11.51%
189.59
+9.76%
172.73
Selling General And Administration
37.72
-56.70%
87.11
+35.37%
64.35
+17.96%
54.55
General And Administrative Expense
37.72
-56.70%
87.11
+35.37%
64.35
+17.96%
54.55
Other Gand A
37.72
-56.70%
87.11
+35.37%
64.35
+17.96%
54.55
Total Expenses
145.01
-43.11%
254.88
+0.37%
253.94
+11.73%
227.29
Operating Income
-145.01
+22.64%
-187.46
+26.18%
-253.94
-11.73%
-227.29
Total Operating Income As Reported
-152.81
+20.08%
-191.19
+36.16%
-299.51
-31.78%
-227.29
EBITDA
-144.27
+22.50%
-186.17
+26.28%
-252.55
-11.82%
-225.86
Normalized EBITDA
-152.67
+26.58%
-207.94
+9.44%
-229.60
+0.97%
-231.85
Reconciled Depreciation
0.74
-42.67%
1.29
-7.20%
1.39
-2.59%
1.43
EBIT
-145.01
+22.64%
-187.46
+26.18%
-253.94
-11.73%
-227.29
Total Unusual Items
8.39
-61.44%
21.77
+194.85%
-22.95
-483.35%
5.99
Total Unusual Items Excluding Goodwill
8.39
-61.44%
21.77
+194.85%
-22.95
-483.35%
5.99
Special Income Charges
-7.80
-108.67%
-3.74
+91.80%
-45.57
0.00
Other Special Charges
—
—
45.57
—
Impairment Of Capital Assets
0.00
-100.00%
3.74
0.00
0.00
Restructuring And Mergern Acquisition
7.80
0.00
0.00
—
Net Income
-137.06
+17.35%
-165.84
+43.24%
-292.19
-23.39%
-236.81
Pretax Income
-136.62
+17.55%
-165.69
+40.16%
-276.89
-25.12%
-221.30
Other Income Expense
8.39
-61.44%
21.77
+194.85%
-22.95
-483.35%
5.99
Gain On Sale Of Security
16.19
-36.52%
25.50
+12.76%
22.62
+277.77%
5.99
Gain On Sale Of Business
—
—
0.00
0.00
Tax Provision
0.44
+149.72%
0.18
+129.45%
-0.60
-28.14%
-0.47
Tax Rate For Calcs
0.00
+0.00%
0.00
+10400.00%
0.00
+0.00%
0.00
Tax Effect Of Unusual Items
1.76
-61.44%
4.57
+10058.78%
-0.05
-483.35%
0.01
Net Income Including Noncontrolling Interests
-137.06
+17.37%
-165.87
+43.26%
-292.31
-23.28%
-237.11
Net Income From Continuing Operation Net Minority Interest
-137.06
+17.35%
-165.84
+43.24%
-292.19
-23.39%
-236.81
Net Income From Continuing And Discontinued Operation
-137.06
+17.35%
-165.84
+43.24%
-292.19
-23.39%
-236.81
Net Income Continuous Operations
-137.06
+17.37%
-165.87
+43.26%
-292.31
-23.28%
-237.11
Minority Interests
0.00
-100.00%
0.03
-75.44%
0.11
-62.87%
0.31
Normalized Income
-143.69
+21.50%
-183.04
+32.03%
-269.29
-10.92%
-242.78
Net Income Common Stockholders
-137.06
+17.35%
-165.84
+43.24%
-292.19
-23.39%
-236.81
Diluted EPS
—
-2.33
+47.87%
-4.47
+0.22%
-4.48
Basic EPS
—
-2.33
+47.87%
-4.47
+0.22%
-4.48
Basic Average Shares
—
71.08
+8.67%
65.41
+23.75%
52.86
Diluted Average Shares
—
71.08
+8.67%
65.41
+23.75%
52.86
Diluted NI Availto Com Stockholders
-137.06
+17.35%
-165.84
+43.24%
-292.19
-23.39%
-236.81
Earnings From Equity Interest Net Of Tax
0.00
0.00
+100.00%
-16.01
+1.65%
-16.28
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
288.97
-32.85%
430.34
-22.00%
551.69
+2.30%
539.31
Current Assets
253.19
-34.42%
386.07
-22.28%
496.72
+9.91%
451.93
Cash Cash Equivalents And Short Term Investments
245.89
-33.74%
371.08
-23.16%
482.92
+10.41%
437.37
Cash And Cash Equivalents
35.99
+6.18%
33.90
+20.91%
28.04
-34.90%
43.07
Other Short Term Investments
209.90
-37.75%
337.18
-25.87%
454.88
+15.36%
394.30
Receivables
0.00
-100.00%
5.00
0.00
-100.00%
7.04
Accounts Receivable
—
—
—
—
Other Receivables
—
5.00
—
6.53
Accrued Interest Receivable
—
—
—
0.51
Prepaid Assets
—
—
—
14.56
Restricted Cash
—
—
—
0.00
Other Current Assets
7.30
-26.89%
9.98
-27.66%
13.80
-5.24%
14.56
Total Non Current Assets
35.78
-19.19%
44.27
-19.46%
54.97
-37.09%
87.38
Net PPE
29.04
-21.99%
37.23
-10.80%
41.73
-16.66%
50.08
Gross PPE
31.82
-23.34%
41.50
-7.54%
44.88
-13.91%
52.14
Accumulated Depreciation
-2.77
+35.10%
-4.27
-35.77%
-3.15
-52.82%
-2.06
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
1.38
-3.30%
1.42
-4.50%
1.49
-32.73%
2.21
Construction In Progress
—
0.00
-100.00%
0.17
+367.57%
0.04
Other Properties
26.27
-26.84%
35.91
-7.89%
38.98
-13.36%
44.99
Leases
4.17
+0.00%
4.17
-1.58%
4.24
-13.41%
4.89
Goodwill And Other Intangible Assets
—
0.00
-100.00%
3.74
+0.00%
3.74
Goodwill
—
0.00
-100.00%
3.74
+0.00%
3.74
Investments And Advances
—
—
0.00
-100.00%
21.21
Long Term Equity Investment
—
—
0.00
-100.00%
21.21
Non Current Prepaid Assets
—
—
—
9.72
Other Non Current Assets
6.74
-4.39%
7.04
-25.84%
9.50
-23.09%
12.35
Total Liabilities Net Minority Interest
72.76
-21.89%
93.15
-18.50%
114.30
+8.56%
105.29
Current Liabilities
36.56
-30.66%
52.73
-23.99%
69.37
+22.45%
56.65
Payables And Accrued Expenses
36.56
-30.66%
52.73
-23.99%
69.37
+22.45%
56.65
Payables
7.21
-3.09%
7.44
-50.17%
14.93
+32.71%
11.25
Accounts Payable
7.21
-3.09%
7.44
-50.17%
14.93
+32.71%
11.25
Current Accrued Expenses
29.35
-35.19%
45.29
-16.81%
54.44
+19.91%
45.40
Pensionand Other Post Retirement Benefit Plans Current
—
—
—
—
Total Tax Payable
—
—
—
—
Income Tax Payable
—
—
—
—
Current Debt And Capital Lease Obligation
—
—
—
—
Current Capital Lease Obligation
—
—
—
—
Total Non Current Liabilities Net Minority Interest
36.20
-10.44%
40.43
-10.02%
44.93
-7.63%
48.64
Long Term Debt And Capital Lease Obligation
35.70
-9.79%
39.58
-8.28%
43.15
-4.46%
45.17
Long Term Capital Lease Obligation
35.70
-9.79%
39.58
-8.28%
43.15
-4.46%
45.17
Non Current Deferred Liabilities
—
—
0.00
-100.00%
0.85
Non Current Deferred Taxes Liabilities
—
—
0.00
-100.00%
0.85
Other Non Current Liabilities
0.50
-41.11%
0.85
-52.30%
1.78
-32.06%
2.62
Stockholders Equity
216.20
-35.88%
337.19
-22.89%
437.28
+0.80%
433.80
Common Stock Equity
216.20
-35.88%
337.19
-22.89%
437.28
+0.80%
433.80
Capital Stock
0.07
-2.82%
0.07
+1.43%
0.07
+18.64%
0.06
Common Stock
0.07
-2.82%
0.07
+1.43%
0.07
+18.64%
0.06
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
69.09
-3.08%
71.28
+0.73%
70.77
+19.37%
59.28
Ordinary Shares Number
69.09
-3.08%
71.28
+0.73%
70.77
+19.37%
59.28
Additional Paid In Capital
1,407.39
+1.18%
1,390.95
+5.09%
1,323.58
+28.32%
1,031.46
Retained Earnings
-1,191.45
-13.00%
-1,054.39
-18.66%
-888.56
-49.00%
-596.37
Gains Losses Not Affecting Retained Earnings
0.20
-64.87%
0.56
-74.57%
2.19
+262.16%
-1.35
Minority Interest
—
0.00
-100.00%
0.11
-51.58%
0.22
Other Equity Adjustments
0.20
-64.87%
0.56
-74.57%
2.19
+262.16%
-1.35
Total Equity Gross Minority Interest
216.20
-35.88%
337.19
-22.91%
437.39
+0.78%
434.02
Total Capitalization
216.20
-35.88%
337.19
-22.89%
437.28
+0.80%
433.80
Working Capital
216.63
-35.01%
333.34
-22.00%
427.35
+8.11%
395.29
Invested Capital
216.20
-35.88%
337.19
-22.89%
437.28
+0.80%
433.80
Total Debt
35.70
-9.79%
39.58
-8.28%
43.15
-4.46%
45.17
Capital Lease Obligations
35.70
-9.79%
39.58
-8.28%
43.15
-4.46%
45.17
Net Tangible Assets
216.20
-35.88%
337.19
-22.23%
433.55
+0.81%
430.07
Tangible Book Value
216.20
-35.88%
337.19
-22.23%
433.55
+0.81%
430.07
Investmentsin Associatesat Cost
—
—
0.00
-100.00%
21.21
Investmentsin Joint Venturesat Cost
—
—
—
21.21
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-125.25
+26.70%
-170.86
+17.79%
-207.82
-26.91%
-163.75
Cash Flow From Continuing Operating Activities
-125.25
+26.70%
-170.86
+17.79%
-207.82
-26.91%
-163.75
Net Income From Continuing Operations
-137.06
+17.37%
-165.87
+43.26%
-292.31
-23.28%
-237.11
Depreciation Amortization Depletion
0.74
-42.67%
1.29
-7.20%
1.39
-2.59%
1.43
Depreciation And Amortization
0.74
-42.67%
1.29
-7.20%
1.39
-2.59%
1.43
Other Non Cash Items
—
-47.42
-415.22%
15.04
—
Stock Based Compensation
20.72
-69.20%
67.27
+22.70%
54.82
+17.04%
46.84
Asset Impairment Charge
4.14
+10.71%
3.74
-24.57%
4.95
0.00
Deferred Tax
0.00
0.00
+100.00%
-0.85
-10.92%
-0.77
Deferred Income Tax
0.00
0.00
+100.00%
-0.85
-10.92%
-0.77
Operating Gains Losses
-0.66
-617.39%
-0.09
-100.56%
16.42
+0.50%
16.34
Unrealized Gain Loss On Investment Securities
-1.24
+76.30%
-5.23
0.00
0.00
Gain Loss On Sale Of PPE
-0.66
-4976.92%
-0.01
-103.20%
0.41
+625.00%
0.06
Change In Working Capital
-9.12
+44.85%
-16.54
-382.06%
5.86
-55.75%
13.25
Change In Receivables
5.00
+200.00%
-5.00
0.00
0.00
Changes In Account Receivables
5.00
+200.00%
-5.00
0.00
0.00
Change In Prepaid Assets
2.99
-51.87%
6.22
+209.51%
-5.68
+14.03%
-6.61
Change In Payables And Accrued Expense
-17.32
+3.92%
-18.02
-265.05%
10.92
-29.68%
15.53
Change In Payable
-17.32
+3.92%
-18.02
-265.05%
10.92
-29.68%
15.53
Change In Account Payable
-17.32
+3.92%
-18.02
-265.05%
10.92
-29.68%
15.53
Change In Other Working Capital
0.20
-23.86%
0.26
-57.62%
0.62
-85.61%
4.33
Investing Cash Flow
131.62
-25.45%
176.56
+497.14%
-44.46
+61.06%
-114.18
Cash Flow From Continuing Investing Activities
131.62
-25.45%
176.56
+497.14%
-44.46
+61.06%
-114.18
Net PPE Purchase And Sale
0.70
+547.44%
-0.16
+73.24%
-0.58
+77.12%
-2.55
Purchase Of PPE
0.00
+100.00%
-0.22
+62.09%
-0.58
+77.12%
-2.55
Sale Of PPE
0.70
+973.85%
0.07
0.00
0.00
Capital Expenditure
—
-0.22
+62.09%
-0.58
+77.12%
-2.55
Net Investment Purchase And Sale
130.93
-25.91%
176.72
+502.77%
-43.88
+60.70%
-111.63
Purchase Of Investment
-139.49
-9.01%
-127.96
+76.70%
-549.18
-3.00%
-533.16
Sale Of Investment
270.41
-11.25%
304.68
-39.70%
505.31
+19.87%
421.53
Net Business Purchase And Sale
—
—
0.00
0.00
Purchase Of Business
—
—
0.00
0.00
Gain Loss On Sale Of Business
0.00
+100.00%
-0.08
0.00
0.00
Financing Cash Flow
-4.28
-4064.81%
0.11
-99.95%
237.30
-9.09%
261.04
Cash Flow From Continuing Financing Activities
-4.28
-4064.81%
0.11
-99.95%
237.30
-9.09%
261.04
Net Common Stock Issuance
-4.28
-1326.93%
0.35
-99.85%
237.30
-9.09%
261.04
Common Stock Payments
-9.98
0.00
0.00
—
Repurchase Of Capital Stock
-9.98
0.00
0.00
—
Net Other Financing Charges
—
-0.24
—
—
Changes In Cash
2.09
-63.95%
5.81
+138.79%
-14.98
+11.32%
-16.89
Beginning Cash Position
36.53
+18.91%
30.72
-32.78%
45.70
-26.98%
62.58
End Cash Position
38.62
+5.73%
36.53
+18.91%
30.72
-32.78%
45.70
Free Cash Flow
-125.25
+26.79%
-171.08
+17.91%
-208.41
-25.32%
-166.30
Income Tax Paid Supplemental Data
0.09
-76.32%
0.36
+156.43%
0.14
+1066.67%
0.01
Amortization Of Securities
-2.76
+65.47%
-8.00
+39.18%
-13.16
-253.21%
-3.73
Common Stock Issuance
5.69
+1531.52%
0.35
-99.85%
237.30
-9.09%
261.04
Earnings Losses From Equity Investments
0.00
0.00
-100.00%
16.01
-1.65%
16.28
Issuance Of Capital Stock
5.69
+1531.52%
0.35
-99.85%
237.30
-9.09%
261.04
Net Preferred Stock Issuance
—
—
—
0.00
Preferred Stock Issuance
—
—
—
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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